Labshake search
Citations for Tocris :
851 - 873 of 873 citations for 5 Benzyloxy pyrimidine 2 carbonitrile since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
-
bioRxiv - Immunology 2024Quote: ... The following inhibitors were added to the cells for 24 hours before harvesting: the NF-κB inhibitor JSH23 (2 µM, Tocris Bioscience), STING inhibitor H151 (5 µM ...
-
bioRxiv - Cell Biology 2024Quote: ... 1.0×105 cells/cm2 for anti-fibrotic condition consisting in FibroGRO 2% FBS supplemented with 75ng/mL of bFGF and 500nM of TGF-β inhibitor (A83-01, Tocris). iPSC-cFbs were maintained for 7 days in culture replacing medium each second day ...
-
bioRxiv - Neuroscience 2023Quote: ... the medium was then changed to 3N (50:50 DMEM/F12:neurobasal with N2 and B27 supplements) without vitamin A with 2 µM DMH1 (Tocris, 4126), 2 µM XAV939 (Cayman Chemical ...
-
bioRxiv - Cell Biology 2022Quote: ... The FFA2R antagonist CATPB ((S)-3-(2-(3-chlorophenyl)acetamido)-4-(4-(trifluoromethyl)-phenyl) butanoic acid) was from Tocris (Britsol, UK).
-
bioRxiv - Physiology 2023Quote: ... the cell medium was replaced with the experimental medium (2 ml/well) consisting of DMEM containing 1 nM of 1,25-dihydroxyvitamin D3 (Tocris; Cat. #2551), as described previously58 ...
-
bioRxiv - Neuroscience 2023Quote: iPSCs were replated at a density of 2 x 104 cells/cm2 in mTeSR medium containing 10 µM Rho kinase inhibitor (Y-27632, Tocris #5849), which was removed after 24 hours ...
-
bioRxiv - Molecular Biology 2024Quote: ... U2OS cells were extracted 1x PBS containing 0.2% Triton-X100 supplemented with PARP inhibitor (olaparib, 1 μM, Selleckchem #S1060) and PARG inhibitor (PDD 00017273, 1 μM, Tocris #5952) to stabilize ADP-ribosylated species for 5 min on ice prior to fixation with 3% paraformaldehyde/2% sucrose for 15 min at ambient temperature ...
-
bioRxiv - Neuroscience 2024Quote: ... The chemogenetic manipulation was carried out 30 minutes after the intraperitoneal injection of CNO at a dosage of 2 mg/kg (TOCRIS Bioscience) or after the administration of saline ...
-
bioRxiv - Molecular Biology 2024Quote: ... the cells were either plated on laminin-coated 10 cm plates at 1.2×107 cells per plate for continued differentiation or expanded in motor neuron progenitor MNP medium (1× N2B27 medium supplemented with 3 mM CHIR99021, 2 mM DMH1 (Tocris, #4126), 2 mM SB431542 ...
-
bioRxiv - Genetics 2024Quote: ... On Day 3 (after 48 hr) media was replaced with CDM containing 2 μM of the Wnt signaling inhibitor Wnt-C59 (5148, Tocris Bioscience) in CDM ...
-
bioRxiv - Neuroscience 2024Quote: ... hM4Di was activated via intraperitoneal (i. p.) injection of the ligand clozapine N-oxide (CNO dihydrochloride, 1–5 mg/kg, Tocris Bioscience, Catalog number 4936) 25-30 minutes before each training session.
-
bioRxiv - Bioengineering 2021Quote: ... the medium was switched to N2B27 medium supplemented with 100 ng/mL VEGFA (ProSpec, CYT-116) and 2 μM forskolin (Tocris Bioscience, 1099) for two days ...
-
bioRxiv - Genomics 2020Quote: ... supplemented with SMAD inhibitors (DMH-1 2 μM Tocris, Cat.: #4423; SB431542-10 μM Tocris, Cat.: #1614 and CHIR99021 3 μM, CHIR Tocris, Cat.: #4423).
-
bioRxiv - Immunology 2024Quote: ... Bone marrow-derived macrophages were plated at 2×105 cells/mL and treated with PBS or 500 ng/mL PAM3CSK4 (Tocris Bioscience, 4633) for 6 hours ...
-
bioRxiv - Microbiology 2024Quote: ... along with 10 µM GSK-3 α and β inhibitor 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea (Tocris) as previously described20 ...
-
bioRxiv - Developmental Biology 2024Quote: ... Between 1.5 × 106 and 3.0 × 106 cells were added to each well in 2 ml mTeSR medium with 10 μM Rho-kinase inhibitor Y-27632 dihydrochloride (Tocris, UK # 1254). To aggregate the cells into the microwells ...
-
bioRxiv - Neuroscience 2020Quote: ... slices were equilibrated for 10 minutes while being continuously superfused at room temperature with oxygenated aCSF at 1-2 ml/min containing picrotoxin (50 μM, Tocris Bioscience, MO, USA) to block GABAA receptor-mediated inhibitory responses.
-
bioRxiv - Neuroscience 2024Quote: ... a third group of animals were treated as those in group 2 with the addition of CB1 receptor antagonist AM251 (1 µM) (Tocris Bioscience, Bristol, UK). After 8 DIV ...
-
bioRxiv - Cell Biology 2024Quote: All cell lines were washed with PBS then starved of amino acids or FBS for 2 hours before treatment with the GPCR antagonists at 1 µM: CNO (Tocris/bio-techne 6329), Isoprenaline/Carvedilol (Sigma/Merck I6504 ...
-
bioRxiv - Bioengineering 2024Quote: ... FAST-STEM hiPSCs grown to 80% confluency were dissociated into single cells using TypLE for 5 minutes and seeded into the Aggrewell at a density of 1.2×105 cells per-well in 1 mL of mTesR Plus with 10 μg/mL ROCK Inhibitor Y-27632 (Tocris Bioscience, Bristol, UK; 1254) and 1% Penicillin-Streptomycin (Life Technologies ...
-
bioRxiv - Bioengineering 2024Quote: ... was obtained through the administration of exponential doses with concentrations of 1 nM to 10 mM at 2 min intervals before the administration of 10 μM scopolamine (Tocris Bioscience Cat#1414/1G). After another equilibrium period ...
-
bioRxiv - Neuroscience 2020Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
-
bioRxiv - Neuroscience 2024Quote: Slices from 6-month-old mice were pre-incubated ≥1.5hours and then bath-perfused during dLight recording with LRRK2 kinase inhibitor MLi-2 (500 nM, Tocris 5756, 45% Captisol® in PBS) or vehicle-control (45% Captisol® in PBS 377.6µL/L aCSF) ...