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Citations for Tocris :
651 - 700 of 873 citations for 5 Benzyloxy pyrimidine 2 carbonitrile since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2024Quote: ... 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone (L-701-324; Tocris); (R)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid ((R)-CPP ...
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bioRxiv - Neuroscience 2024Quote: ... VU0360172 [N-cyclobutyl-6-(2-(3-fluorophenyl)ethynyl) pyridine-3-carboxamide] was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2024Quote: ... USA) and superfused with ACSF containing 2 mM CaCl2 and 20 µM bicuculline methiodide (Tocris) at a rate of 3 – 4 ml/min at RT ...
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bioRxiv - Cell Biology 2023Quote: ... the samples were blocked for 2 hours in HBSS with 4% BSA (Tocris BioScience, #5217). Incubation with primary antibody rabbit anti progesterone receptor (1:500 in 4% BSA ...
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bioRxiv - Neuroscience 2023Quote: ... and exposure to a cocktail of small molecules containing 2 μM each of Dorsomorphin (Tocris), A83-01 (Tocris ...
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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfallsbioRxiv - Neuroscience 2023Quote: ... a single submaximal concentration (10 µM) of WIN-55,212-2 or HU-210 (Tocris #0966) was used ...
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bioRxiv - Cancer Biology 2023Quote: ... N-(1,3,4-thiadiazol-2-yl) pyridine-3-carboxamide dihydrochloride (TGN-020, Tocris Cat No 5425) was used in vitro at 10-100 μM ...
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bioRxiv - Neuroscience 2023Quote: ... P3029) and 2-methyl-6-(phenylethynyl)pyridine (MPEP; Tocris, Ellisville, MO, Cat. No. 1212/10), solutions were made fresh in sterile saline before use ...
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bioRxiv - Neuroscience 2023Quote: ... organoids were placed in HEPES buffer containing CNQX/APV (2 µM/50 µM, Tocris Bioscience) and imaged immediately.
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bioRxiv - Pharmacology and Toxicology 2023Quote: ... [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl] phenylmethanone (VCP 171; Tocris, 1018830-99-3), 5-[2-(5-nitro-2-furanyl)ethenyl]-2-furancarboxylic acid ...
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bioRxiv - Genomics 2023Quote: ... spent media was replaced with fresh CDM containing 2 µM Wnt-C59 (5148, Tocris Bioscience). CDM was used to replace media on Days 5 ...
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bioRxiv - Immunology 2024Quote: ... 8-to 12-week-old mice were treated with 2 nmol calcipotriol (MC903, Tocris Bioscience) in 10 μL of 100% ethanol (EtOH ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... and (11R)-2-Methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraene (WIN55,212-2) were acquired from Tocris (Bristol, UK). [(1S,2S,5S)-2-[2,6-Dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol (HU308 ...
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bioRxiv - Neuroscience 2024Quote: ... with a dosage of 2 mg/kg of Methoxy-X04 dye (Tocris Bioscience, Bristol, UK). In our setup ...
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bioRxiv - Neuroscience 2021Quote: ... C57bl/6j and global Gabrd-/- mice were infused with saline solution (0.9 % NaCl) or 5 μg allo (2.5 μg/μl, Tocris). For chronic unpredictable stress (CUS) ...
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Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potentialsbioRxiv - Neuroscience 2021Quote: ... 4 or 8 μl of 6-OHDA (5 μg in 1 μl saline containing 0.1% ascorbic acid; Tocris, Bristol ...
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bioRxiv - Molecular Biology 2020Quote: ... and 200 μL of flow buffer supplemented to a final concentration of 5 μM DFHO dye (TOCRIS Bioscience) was added prior to analysis by flow cytometry.
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bioRxiv - Genomics 2022Quote: ... and cultured for 24 hours in iPS media supplemented with 5 μM Y-27632 (Tocris Biosciences, Bristol, UK) prior to maintenance in iPS media ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... or the α7-selective nAChR antagonist methyllycaconitine citrate (MLA; 5 mg/kg in sterile saline; Tocris, Bristol, UK). These pharmacological reagents were injected s.c ...
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bioRxiv - Neuroscience 2023Quote: Gabra6-Cre::Thy1-ChR2::DREADD mice received intra-peritoneal injections of CNO (5 mg/kg; Tocris Bioscience, #4936) 60-90 min before starting eyeblink experiments.
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bioRxiv - Cancer Biology 2023Quote: ... the STING inhibitor C-176 was used at a final concentration of 5 µM (Tocris Bioscience (Bio-Techne), Bristol ...
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bioRxiv - Cell Biology 2023Quote: ... differentiation was initiated by treating the hESCs with cardiomyocyte differentiation basal medium (CDBM) with 5 mM CHIR99021 (Tocris) to activate Wnt/β-catenin signaling and form the mesendoderm layer ...
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bioRxiv - Cell Biology 2024Quote: To induce DNA damage cells were treated with 5 µM or 25 µM of cisplatin (CSP; Tocris #2251) and 13 µM of bleomycin (BLE ...
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bioRxiv - Physiology 2024Quote: ... the medium was replaced by RPMI1640 medium supplemented with B27 minus insulin and 5 μM IWP2 (Tocris Biosciences). On day 5 ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2020Quote: ... Readings were taken before and 3–4 min after application of 20 μM 2-AG (Tocris) to activate CB1R or the eCB sensor.
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bioRxiv - Neuroscience 2021Quote: ... 6R)-4-Amino-2-oxabicyclo [3.1.0] hexane-4,6-dicarboxylic acid disodium salt (LY379268, 100 µM, Tocris); calmidazolium chloride (CMZ ...
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bioRxiv - Neuroscience 2020Quote: ... JNJ16259685 and 2-Methyl-6-(phenylethynyl)pyridine (MPEP) hydrochloride were purchased from Tocris (Minneapolis MN, USA). (±)-Sulpiride was purchased from MilliporeSigma ...
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bioRxiv - Neuroscience 2020Quote: ... WIN 55,212-2 (WIN, 0.5 µg/0.5-µL infusion/hemisphere; n = 11; Tocris Bioscience, Minneapolis, MN) or VEH (10% DMSO ...
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bioRxiv - Cancer Biology 2022Quote: ... One hour before dsDNA transfection cells were pre-treated with 2 µM NU7441 (#3712, Biotechne/Tocris) in OptiMEM and were subsequently transfected with dsDNA (1 µg/ml) ...
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Cancer Biology 2022Quote: ... 2% Sodium deoxycholate and 0.2% SDS including protease inhibitors (Aprotinin (TOCRIS Bioscience Cat. no. 4139/10) Leupeptin (Fisher Scientific ...
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bioRxiv - Neuroscience 2020Quote: NNC-711 (1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride) from Tocris
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bioRxiv - Developmental Biology 2021Quote: ... Lin- c-Kit+ cells were sorted into 2%FCS-PBS with 100µM IWR-1 (Tocris, 3532) or control vehicle ...
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bioRxiv - Microbiology 2020Quote: ... cells were pretreated for 3h before infection with Tautomycetin (0.8 μM, Tocris Bioscience, 119757-73-2) or Okadaic acid (0.1 μM ...
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bioRxiv - Molecular Biology 2021Quote: Cells were treated for 2 hrs with vehicle (DMSO) or with 250 nM Torin1 (Tocris Biosciences), or for 1 hr with 50 μM Ly29004 (Tocris Biosciences ...
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bioRxiv - Neuroscience 2022Quote: ... we slowly infused 200 nl of the GABAA receptor agonist muscimol (Tocris; 2 μM in saline) into the target area using a micro-syringe pump (KD Scientific ...
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bioRxiv - Neuroscience 2024Quote: ... The following competitive antagonists were employed for microscopical experiments: trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline (L-689-560; Tocris); 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone (L-701-324 ...
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bioRxiv - Developmental Biology 2024Quote: ... Cells were treated as control or with 2 µM DDR1 inhibitor DDR1-in-1 (Tocris 5077) or 5 µM RUNX1 inhibitor AI-10-104 (Aobious AOB17076) ...
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Neuroscience 2024Quote: Glymphatic inhibition was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience). Mice were treated i.p ...
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bioRxiv - Neuroscience 2024Quote: ... supplemented with 1.25% DMSO and 1.25% Tween 80) or BMS-204352 (2 mg per kg, Tocris) were delivered by intraperitoneal injection 30 min before behavioral testing (as described previously Zhang) ...
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bioRxiv - Neuroscience 2024Quote: ... 2 weeks differentiated BMP4 and CNTF astrocytes were treated with ROCK inhibitor Y27632 (Tocris, 25 μM) or LAT B (Sigma ...
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bioRxiv - Cell Biology 2020Quote: ... 0.5 mL fresh RPMI 1640 containing B-27 supplement minus insulin was added to 0.5 mL conditioned (old) medium and added to cells along with 5 µM IWP2 (Tocris). Medium was aspirated at Day 5 and replenished with fresh RPMI 1640 containing B-27 supplement minus insulin ...
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bioRxiv - Cell Biology 2020Quote: ... Electroporated cells were seeded in fresh E8 media containing 5 μM Y-27632 dihydrochloride (a selective ROCK inhibitor, Tocris) and allowed to recover for 48 hours before antibiotic selection.
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bioRxiv - Neuroscience 2021Quote: ... All neurons were recorded in control conditions and after >5 min of bath application of 1 µM DHβE (Tocris).