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3551 - 3600 of 10000+ citations for 6 Methyl 1 2 4 triazolo 4 3 b pyridazine since 2019

• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... DRP1 (1:1000; Cell Signaling, Cat#), OXPHOS Cocktail (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... SOD2 (1:1000; Cell Signaling, Cat#), Catalase (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Mitofusin2 (1:1000; Cell Signaling, Cat#), DRP1 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... ULK1 (1:1000; Cell Signaling, Cat#), PGC-1α (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... S6K1 (1:1000; Cell Signaling, Cat#), p-4E-BP1 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... ACC1 (1:1000; Cell Signaling, Cat#), p-ULK1 (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Synapsin2 (1:1000; Cell Signaling, Cat#), ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Catalase (1:1000; Cell Signaling, Cat#), p-mTOR (1:1000 ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... eEF2 (1:1000; Cell Signaling, Cat#), PSD-95 (1:1000 ...
• Werner syndrome protein (WRN) regulates cell proliferation and the human papillomavirus 16 life cycle during epithelial differentiation

  Claire D. James, et al., bioRxiv - Molecular Biology 2020

  Quote: ... BrdU (1/200, Cell Signaling Technology), phospho-Histone H2AX (Ser139 ...
• Opposing functions of the Hda1 complex and histone H2B mono-ubiquitylation in regulating cryptic transcription initiation in Saccharomyces cerevisiae

  Margaret K. Shirra, et al., bioRxiv - Molecular Biology 2020

  Quote: ... α-H2Bub (Cell Signaling #5546; 1:1000), α-G6PDH (Sigma #A9521 ...
• Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH

  Lian E.M. Stadhouders, et al., bioRxiv - Molecular Biology 2020

  Quote: ... α-TUBULIN (1:10000; Cell Signaling Technology, Cat# 2125 ...
• Myotube hypertrophy is associated with cancer-like metabolic reprogramming and limited by PHGDH

  Lian E.M. Stadhouders, et al., bioRxiv - Molecular Biology 2020

  Quote: ... PHGDH (1:1000; Cell Signaling Technology, Cat# 13428 ...
• Prostaglandin E₁ as therapeutic molecule for Nephronophthisis and related ciliopathies

  Hugo Garcia, et al., bioRxiv - Cell Biology 2022

  Quote: ... PKAS (1/1000e; Cell Signaling, 9624), DAPI (1/2000e ...
• Transgenerational transcriptional heterogeneity from cytoplasmic chromatin

  Stamatis Papathanasiou, et al., bioRxiv - Cell Biology 2022

  Quote: ... H3K9me2 (Cell Signaling #9753S, 1:400), POM121 (Proteintech 15645-1-AP ...
• Transgenerational transcriptional heterogeneity from cytoplasmic chromatin

  Stamatis Papathanasiou, et al., bioRxiv - Cell Biology 2022

  Quote: ... H3K9ac (Cell Signaling #9649S, 1:400), H3K9me2 (Cell Signaling #9753S ...
• β-Catenin tumour-suppressor activity depends on its ability to promote Pro-N-Cadherin maturation

  Antonio Herrera, et al., bioRxiv - Cell Biology 2019

  Quote: ... β-Catenin (Cell signaling, #9562; 1:500), Golgin97 (Invitrogen #A21270 ...
• SAMHD1 regulates human papillomavirus 16 induced cell proliferation and viral replication during differentiation of oral keratinocytes

  Claire D. James, et al., bioRxiv - Cancer Biology 2019

  Quote: ... SAMHD1 (1:1000, Cell Signaling Technology), BrdU (1:200 ...
• SAMHD1 regulates human papillomavirus 16 induced cell proliferation and viral replication during differentiation of oral keratinocytes

  Claire D. James, et al., bioRxiv - Cancer Biology 2019

  Quote: ... BrdU (1:200, Cell Signaling Technology), Cyclin E (1:1000 ...
• Anti-tumor effects of an Id antagonist with no acquired resistance

  Paulina M. Wojnarowicz, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Vimentin (5741, Cell Signaling 1:500), Cyclin D1 (2978 ...
• PI16 is a non-neuronal regulator of neuropathic pain

  Pooja Singhmar, et al., bioRxiv - Neuroscience 2019

  Quote: ... pMLC2 (1:200, Cell Signaling 3675S) followed by Alexa-594 ...
• PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

  Sang Hee Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... 4EBP1 (Cell Signaling Technology; 1:1000), β-actin (Cell Signaling Technology ...
• PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

  Sang Hee Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... β-actin (Cell Signaling Technology; 1:2000) and Vinculin (Santa Cruz Biotechnology ...
• Estrogen-related receptor beta activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma

  DM Tiek, et al., bioRxiv - Cancer Biology 2019

  Quote: ... PARP (1:1000, Cell Signaling, #9542L), CDKN1A/p21 (1:300 ...
• Estrogen-related receptor beta activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma

  DM Tiek, et al., bioRxiv - Cancer Biology 2019

  Quote: ... EGFR (1:1000, Cell Signaling, #2232S), MGMT (1:1000 ...
• Estrogen-related receptor beta activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma

  DM Tiek, et al., bioRxiv - Cancer Biology 2019

  Quote: ... MGMT (1:1000, Cell Signaling, #2739S), Cortactin (1:1000 ...
• Distinct Vegfa isoforms control endothelial cell proliferation through PI3 kinase signalling mediated regulation of cdkn1a/p21

  Martin Lange, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Akt (1:1000; #9272; Cell Signaling). Primary antibodies were detected using mouse IgG HRP linked whole Ab (1:4000 ...
• AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

  Wenting Du, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Arginase 1 (Arg1, Cell Signaling, 93668), SOX9 (EMD Millipore ...
• Ribosomal protein RACK1 facilitates efficient translation of poliovirus and other viral IRESs

  Ethan LaFontaine, et al., bioRxiv - Molecular Biology 2019

  Quote: ... L13a (1:1000, Cell Signaling #2765S), actin (1:1000 ...
• The unjamming transition is distinct from the epithelial-to-mesenchymal transition

  Jennifer A. Mitchel, et al., bioRxiv - Biophysics 2019

  Quote: ... vimentin (1:100, Cell Signaling Technology), cellular fibronectin (1:200 ...
• Generation of inducible SMARCAL1 knock-down iPSC to model severe Schimke immune-osseous dysplasia reveals a link between replication stress and altered expression of master differentiation genes

  Giusj Monia Pugliese, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-pCHK2 (1:1000; Cell Signaling), anti-CHK2 (1:1000 ...
• Generation of inducible SMARCAL1 knock-down iPSC to model severe Schimke immune-osseous dysplasia reveals a link between replication stress and altered expression of master differentiation genes

  Giusj Monia Pugliese, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-KAP1 (1:1000; Cell Signaling), anti p-ATM (1:800 ...
• Generation of inducible SMARCAL1 knock-down iPSC to model severe Schimke immune-osseous dysplasia reveals a link between replication stress and altered expression of master differentiation genes

  Giusj Monia Pugliese, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-CHK2 (1:1000; Cell Signaling), anti-pKAP1 (1.1000 ...
• GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling

  Rachel K. Lex, et al., bioRxiv - Developmental Biology 2019

  Quote: ... 1:1000 GAPDH (Cell Signaling 5174), 1:1000 H3K27ac (Abcam Ab4729) ...
• GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling

  Rachel K. Lex, et al., bioRxiv - Developmental Biology 2019

  Quote: ... 1:4000 M2 Flag (Sigma 3165),1:4000 H3 (Cell Signaling 4499), 1:1000 GAPDH (Cell Signaling 5174) ...
• ROCK Inhibitor Increases Proacinar Cells in Adult Salivary Gland Organoids

  Matthew Koslow, et al., bioRxiv - Cell Biology 2019

  Quote: ... CC3 (1:200, #Cell Signaling 9661), RFP (1:200 ...
• EML4-ALK V3 drives cell migration through NEK9 and NEK7 kinases in non-small-cell lung cancer

  Laura O’Regan, et al., bioRxiv - Cancer Biology 2019

  Quote: ... pALK (1:1000, Cell Signaling Technology) and GAPDH (1 µg/ml ...
• EML4-ALK V3 drives cell migration through NEK9 and NEK7 kinases in non-small-cell lung cancer

  Laura O’Regan, et al., bioRxiv - Cancer Biology 2019

  Quote: ... ALK (1:2000, Cell Signaling technology), pALK (1:1000 ...
• Inhibiting TG2 sensitizes lung cancer to radiotherapy through interfering TOPOIIα-mediated DNA repair

  Xiao Lei, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Vimentin (1:200; Cell Signaling Tech.) and α-SMA (1:200 ...
• Inhibiting TG2 sensitizes lung cancer to radiotherapy through interfering TOPOIIα-mediated DNA repair

  Xiao Lei, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p65 (1:200; Cell Signaling Tech.), E-cadherin (1:200 ...
• Altered m⁶A modification of specific cellular transcripts affects Flaviviridae infection

  Nandan S. Gokhale, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-H2A.X (Cell Signaling, 1:1000), anti-U170K serum (gift of Dr ...
• Altered m⁶A modification of specific cellular transcripts affects Flaviviridae infection

  Nandan S. Gokhale, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-HSPA5 (Cell Signaling, 1:1000), anti-H2A.X (Cell Signaling ...
• Altered m⁶A modification of specific cellular transcripts affects Flaviviridae infection

  Nandan S. Gokhale, et al., bioRxiv - Molecular Biology 2019

  Quote: ... anti-eIF2α (Cell Signaling, 1: 1000), anti-phospho-eIF2α (Cell Signaling ...
• Phosphorylation of Nephrin induces phase separated domains that move through actomyosin contraction

  Soyeon Kim, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-HA (Cell Signaling, 1:1000). For western blotting with 4G10 antibody ...
• The impact of gut microbiota on depressive-like behaviors and adult hippocampal neurogenesis requires the endocannabinoid system

  Grégoire Chevalier, et al., bioRxiv - Neuroscience 2019

  Quote: ... or GAPDH (1:1000, Cell Signaling) antibodies ...
• Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling

  Callie P. Wigington, et al., bioRxiv - Cell Biology 2019

  Quote: ... Myc (1:3,000; Cell Signaling 2276S), and β-Actin (1:3,000 ...
• Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence

  Alberto Granzotto, et al., bioRxiv - Neuroscience 2019

  Quote: ... rabbit P53 1:1000 (Cell Signaling); rabbit p-ERK5 and rabbit ERK5 1:1000 (Cell Signaling) ...
• Proliferation control of kidney interstitial cells

  Sarah S. McCarthy, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-Smad3 (1:3,000; Cell Signaling) and anti-pSmad1/5/8 (1:1000 ...
• PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

  Sang Hee Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... p62 (Cell Signaling Technology; 1:1000), Cathepsin D (Calbiochem 1:1000) ...
• MCL-1 inhibition by selective BH3 mimetics disrupts mitochondrial dynamics in iPSC-derived cardiomyocytes

  Megan L. Rasmussen, et al., bioRxiv - Cell Biology 2019

  Quote: ... MCL-1 (Cell Signaling Technologies #94296S), TOM20 (Cell Signaling Technologies # 42406S) ...