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3151 - 3200 of 10000+ citations for 8 BROMO 7 3 CHLOROPROPYL 1 3 DIMETHYL 2 3 6 7 TETRAHYDRO 1H PURINE 2 6 DIONE since 2019

• Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

  Laura Sebastian Monasor, et al., bioRxiv - Neuroscience 2019

  Quote: ... CSF1R (1:1000, 3152, Cell Signaling) and FABP5 (1:400 ...
• Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

  Júlia Canet-Pons, et al., bioRxiv - Neuroscience 2019

  Quote: ... RIPK1 (Cell Signaling 3493S, 1:500), TDP43 (Abcam ab41881 ...
• Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

  Júlia Canet-Pons, et al., bioRxiv - Neuroscience 2019

  Quote: ... CASP3 (Cell Signaling 9665, 1:1000), GFAP (Dako ZO334 ...
• Enhanced FGFR3 activity in post-mitotic principal neurons during brain development results in cortical dysplasia and axon miswiring

  Jui-Yen Huang, et al., bioRxiv - Neuroscience 2020

  Quote: ... Draq5 (1:10,000 dilution, Cell Signaling) or 4′,6-diamidino-2-phenylindole (DAPI ...
• Transmission-selective muscle pathology induced by active propagation of mutant huntingtin across the human neuromuscular synapse

  Dinamarca C. Margarita, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:800 V5 (D3H8Q, Cell Signaling), 1:40 NF2H3 (AB2314897 ...
• The fragile X mental retardation protein promotes adjustments in cocaine self-administration that preserve reinforcement level

  Jessica L. Huebschman, et al., bioRxiv - Neuroscience 2020

  Quote: ... NR2B (Cell Signaling 14544S, 1:1000), and GAPDH (Fisher-Scientific AM4300 ...
• EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

  Kai Voeltzke, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MYCN (1:1,000, Cell Signaling #9405), GAPDH (1:1,000 ...
• EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

  Kai Voeltzke, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GAPDH (1:1,000, Cell Signaling #2118), and β-Actin (1:5,000 ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... NeuN (1:500, Cell Signaling Technology), Brn3a (1:200 ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... NFM (1:1000, Cell Signaling Technology), GFP (1:1000 ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... MUC5AC (1:500) (Cell Signaling Technologies) and MUC5B (1:500 ...
• Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8⁺ T cell-mediated immunopathology

  S. Wali, et al., bioRxiv - Immunology 2020

  Quote: ... and cCasp3 (1:500; Cell Signaling). EdU ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... ULK1 (1:1000; Cell Signaling 8054), p-ULK1 (1:1000 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... mTOR (1:1000; Cell Signaling 2972), p-mTOR (1:1000 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH (1:1000; Cell Signaling 2118), ULK1 (1:1000 ...
• Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content related to inflammation and recovery processes

  Annika Bub, et al., bioRxiv - Neuroscience 2021

  Quote: ... NCAM (1:1,000, #99746; Cell Signaling), P2Y12 (1:500 ...
• Extracellular vesicles induce aggressive phenotype of luminal breast cancer cells by PKM2 phosphorylation

  Seo Young Kang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GLUT1 (1:1000; D3J3A; Cell Signaling), PKM2 (1:1000 ...
• Extracellular vesicles induce aggressive phenotype of luminal breast cancer cells by PKM2 phosphorylation

  Seo Young Kang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PKM2 (1:1000; D78A4; Cell Signaling), anti-phospho Y105 PKM2 (1:1000 ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total 4EBP1 (Cell Signaling; 1:1000), pAKT308 (Cell Signaling ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total S6 (Cell Signaling; 1:1000), p4EBP1 (Fluidigm ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total Akt (Cell Signaling; 1:1000), pGSK3ß (Cell Signaling ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Total GSK3ß (Cell Signaling; 1:1000), ß-actin (Cell Signaling ...
• MYC promotes immune-suppression in TNBC via inhibition of IFN signaling

  Dario Zimmerli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Geminin (Cell Signaling, #9718, 1:200) or cGAS (1:200 ...
• MYC promotes immune-suppression in TNBC via inhibition of IFN signaling

  Dario Zimmerli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cGAS (1:1000, Cell Signaling, #15102), STING (1:1000 ...
• MYC promotes immune-suppression in TNBC via inhibition of IFN signaling

  Dario Zimmerli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... BRCA1 (1:1000, Cell Signaling, #9010), cGAS (1:1000 ...
• mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

  Madeline G. Andrews, et al., bioRxiv - Neuroscience 2020

  Quote: ... pS6 (Cell Signaling, 2211S, 1:500), p4EBP1 (Cell Signaling Technology ...
• Membrane-associated shortened Trk receptors promote neuroprotection and robust axon regeneration without ligands

  Euido Nishijima, et al., bioRxiv - Neuroscience 2022

  Quote: ... pAKT antibody (1:1000, Cell Signaling) or anti-RBPMS antibody (1:1000 ...
• Endothelial-derived sphingolipids are required for vascular development and systemic lipid homeostasis

  Andrew Kuo, et al., bioRxiv - Developmental Biology 2022

  Quote: ... LEF1 (Cell Signaling Technology, 1:200), TFRC (Novus Biologicals ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... Cdc42 (Cell Signaling, #2466, 1:1000), RhoA (67B9 ...
• Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

  Shikai Hu, et al., bioRxiv - Pathology 2022

  Quote: ... Ki67 (Cell signaling, 12202, 1:500), CYP2F2 (Santa Cruz Biotechnology ...
• Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

  Shikai Hu, et al., bioRxiv - Pathology 2022

  Quote: ... GFP (Cell signaling, 2956, 1:100), Cyclin D1 (abcam ...
• Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

  Shikai Hu, et al., bioRxiv - Pathology 2022

  Quote: ... GFP (Cell signaling, 2956, 1:100), in antibody diluent and incubated at 4°C overnight ...
• G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

  Ewa Bielczyk-Maczynska, et al., bioRxiv - Physiology 2022

  Quote: ... S6 (Cell Signaling, #2317, 1:1,000), phospho-S6 (Cell Signaling ...
• G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

  Ewa Bielczyk-Maczynska, et al., bioRxiv - Physiology 2022

  Quote: ... Akt (Cell Signaling, #58295, 1:1,000), phospho-Akt (Cell Signaling ...
• Plasticity in airway smooth muscle differentiation during mouse lung development

  Katharine Goodwin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Lef1 (Cell Signaling 2230, 1:200), pMLC2 (Cell Signaling 3671 ...
• The isoforms of pyruvate kinase act as nutrient sensors for the β-cell K_ATP channel

  Hannah R. Foster, et al., bioRxiv - Cell Biology 2022

  Quote: ... PKm2 (Cell Signaling #7067; 1:1000), PCK2 primary antibodies (Cell Signaling #6924 ...
• The integrated stress response induces a common cell-autonomous death receptor 5-dependent apoptosis switch

  Nerea L. Muniozguren, et al., bioRxiv - Cell Biology 2022

  Quote: ... PARP1(Cell Signaling 9532, 1:1000), caspase-8 (Cell Signaling Technology 9746 ...
• Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

  Cody A. Rutledge, et al., bioRxiv - Physiology 2022

  Quote: ... S6 (1:1000, Cell Signaling, #2217), p-4EBP1 (Thr37/46 ...
• Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

  Cody A. Rutledge, et al., bioRxiv - Physiology 2022

  Quote: ... 4EBP1 (1:1000, Cell Signaling, #9644), nitrotyrosine (Santa Cruz ...
• A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer

  Zinab O. Doha, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD4 (Cell Signaling #25229, 1:100); MHCII (eBioscience #eB14-5321 ...
• Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer

  Tong Xu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... NUMB (1:1000, Cell Signaling, C29G11) and β-actin (1:2000 ...
• AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

  Giorgio Caratti, et al., bioRxiv - Physiology 2020

  Quote: ... AMPKa (Cell Signaling, 2532, 1:1000), p-ACC (Cell Signaling ...
• AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

  Giorgio Caratti, et al., bioRxiv - Physiology 2020

  Quote: ... ACC (Cell Signaling, 3662, 1:1000), with β-actin (Sigma-Aldrich ...
• AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

  Giorgio Caratti, et al., bioRxiv - Physiology 2020

  Quote: ... GR (Cell Signaling, 3660, 1:1000), p-p38 (Cell Signaling ...
• AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

  Giorgio Caratti, et al., bioRxiv - Physiology 2020

  Quote: ... p38 (Cell Signaling, 8690, 1:1000) with β-actin (Sigma-Aldrich ...
• The Drosophila metallopeptidase superdeath decouples apoptosis from the activation of the ER stress response

  Rebecca A.S. Palu, Clement Y. Chow, bioRxiv - Genetics 2019

  Quote: ... and V5 (1:500, Cell Signaling #13202S ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... pIRF3 (1:1000; Cell Signaling #29047), IRF3 (1:1000 ...
• Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella-containing vacuole

  Ila S. Anand, Won Young Choi, Ralph R. Isberg, bioRxiv - Microbiology 2019

  Quote: ... Rab8A (Cell Signaling Technologies, 1:500), Rab8B (Proteintech ...
• Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

  Elizabeth Min, et al., bioRxiv - Cell Biology 2019

  Quote: ... Nrp1 (1:2000; Cell Signaling; #3725), Endoglin (1:2000 ...
• A mouse model for spinal muscular atrophy provides insights into non-alcoholic fatty liver disease pathogenesis

  Marc-Olivier Deguise, et al., bioRxiv - Pathology 2020

  Quote: ... Creb (Cell Signaling 9104, 1:1000), MitoOxphos (Abcam ...