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3051 - 3100 of 10000+ citations for 8 BROMO 7 3 CHLOROPROPYL 1 3 DIMETHYL 2 3 6 7 TETRAHYDRO 1H PURINE 2 6 DIONE since 2019

• Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

  Sinae Kim, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-COX2 (1:1000, Cell Signaling), anti-PTGES1 (1:500 ...
• Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2

  Senem Merve Fred, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... pTRKB.Y816 (1:1000, #4168, Cell Signaling) or GAPDH (1:5000 ...
• Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2

  Senem Merve Fred, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... pTRKB.Y515 (1:1000, #9141, Cell Signaling), pTRKB.Y706/7 (1:1000 ...
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Snail1 (Cell Signaling, 3895S, 1/500), Slug (Cell Signaling ...
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Slug (Cell Signaling, 9585S, 1/500) Vimentin (Cell Signaling ...
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Vimentin (Cell Signaling, 5741S, 1/500), E-cadherin (Abcam ...
• Site-specific ubiquitination of the E3 ligase HOIP regulates cell death and immune signaling

  Lilian M. Fennell, et al., bioRxiv - Cell Biology 2019

  Quote: ... cleaved (Cell Signaling, 9661, 1:100) F4.80 (Bio Rad ...
• Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV

  Kumari G. Lokugamage, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-pSTAT1 (1:1000, Cell Signaling) or anti-beta actin (1:5000 ...
• Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

  JR Ishibashi, et al., bioRxiv - Biochemistry 2021

  Quote: ... mTOR (Cell Signaling 2972, 1:1000), pS6 (Cell Signaling 2215 ...
• Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

  JR Ishibashi, et al., bioRxiv - Biochemistry 2021

  Quote: ... pS6 (Cell Signaling 2215, 1:1000), S6 (Cell Signaling 2117 ...
• Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

  JR Ishibashi, et al., bioRxiv - Biochemistry 2021

  Quote: ... S6 (Cell Signaling 2117, 1:1000), histone 4 (Lys16 ...
• p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis

  André-Claude Mbouombouo Mfossa, et al., bioRxiv - Neuroscience 2020

  Quote: ... (rabbit, 1:1000, Cell Signaling (3377)) ...
• Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling

  Megha Amar, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-RhoA (1:1000; Cell Signaling), and anti-Gapdh (1:5000 ...
• Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons

  Anthony H. Tsang, et al., bioRxiv - Neuroscience 2020

  Quote: ... Ha (1:1000, Cell Signaling Technology) and GFRAL (1:200 ...
• Yin Yang 1 sets up the stage for cerebellar astrocyte maturation

  Karli Mockenhaupt, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-calbindin (Cell Signaling; 1:200), and anti-YY1 (Bethyl Laboratories ...
• Yin Yang 1 sets up the stage for cerebellar astrocyte maturation

  Karli Mockenhaupt, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-GFAP (Cell Signaling; 1:300), anti-IBA (Wako Chemicals ...
• Full-length isoform transcriptome of developing human brain provides new insights into autism

  Kevin Chau, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-SKP1 (1:1000; Cell Signaling), and anti-βactin (1:10000 ...
• Lithium inhibits tryptophan catabolism via the inflammation-induced kynurenine pathway in human microglia

  Ria Göttert, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-PU.1 (Cell Signaling) 1:200 ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... LC3 1:500 (Cell signaling #12741); Atg7 1:500 (Cell signaling #8558) ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... S6 1:500 (Cell signaling #2217), JUN 1:500 (Cell signaling #9165) ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... Atg7 1:500 (Cell signaling #8558); p62 1:500 (Enzo Life Sciences #BML-PW9860) ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... JUN 1:500 (Cell signaling #9165), p-AKT (Cell signaling #9271) ...
• Prenatal Methadone Exposure Disrupts Behavioral Development and Alters Motor Neuron Intrinsic Properties and Local Circuitry

  Gregory G. Grecco, et al., bioRxiv - Neuroscience 2020

  Quote: ... Draq5 (1:10,000 dilution, Cell Signaling) was included in the secondary antibody solution to stain nuclei ...
• A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

  Nikhil Gupta, et al., bioRxiv - Molecular Biology 2021

  Quote: ... α-DNMT3A (Cell Signaling #3598, 1:500), α-DNMT3B (Novus #56514 ...
• APOBEC3A drives acquired resistance to targeted therapies in non-small cell lung cancer

  Hideko Isozaki, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Actin (1:1000, Cell Signaling #4970), γH2AX (1:1000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... H3K27me3 (1:5,000; Cell Signaling Technology), H3K9me3 (1:5,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... H3K27Ac (1:500; Cell Signaling Technology), H3K9me3 (1:1,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... EZH2 (1:1,000; Cell Signaling Technology), and SUZ12 (1:1,000 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SUV39H1 (1:1,000, Cell Signaling Technology), EZH2 (1:1,000 ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... JNK (1:1,000, Cell Signaling Technology #9252S or 1:2,000 Santa Cruz Biotechnology sc-7345) ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MKK7 (1:1,000, Cell Signaling Technology #4172S or 1:2,000 ...
• In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets

  Michela Carlet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... MCL-1 (Clone D2W9E, Cell signaling) or respective isotype controls (Cat. ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p62 1:1000 (Cell Signaling, 5114), LC3B 1:1000 (D11 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HSP90 1:1000 (Cell Signaling, 4877S), Rheb 1:1000 (E1G1R ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p70S6K1 1:1000 (Cell Signaling, 9202), GAPDH 1:10,000 (14C10 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... SDHA 1:1000 (Cell Signaling, 5839), Tom20 1:100 (F-10 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Akt 1:1000 (Cell Signaling, 9272), Deptor 1:1000 (Novus Bio ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... CDK4 (Cell Signaling #12790, 1:1000), CDK2 (Santa Cruz Biotechnology #sc-6248 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... Parkin (1:1,000, Cell Signaling, Prk8), PINK1 (1:1,000 ...
• Reduced Shmt2 expression impairs mitochondrial folate accumulation and respiration, and leads to uracil accumulation in mouse mitochondrial DNA

  Joanna L. Fiddler, et al., bioRxiv - Biochemistry 2021

  Quote: ... and GAPDH (Cell Signaling, 1:2000) were used ...
• Multiscale profiling of enzyme activity in cancer

  Ava P. Soleimany, et al., bioRxiv - Bioengineering 2021

  Quote: ... PDGFRβ (3169, Cell Signaling, 1: 100), and desmin (ab227651 ...
• The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

  Francesca Boscolo Sesillo, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-SMA (Cell Signaling, 19245S, 1:100), collagen I (Invitrogen ...
• Single cell 3’UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autism

  Manuel Göpferich, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH (Cell Signaling, Rabbit, 1:1000), Histone H3 (Cell Signaling ...
• SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice

  Alan T. Tang, et al., bioRxiv - Microbiology 2021

  Quote: ... β-Actin (1:1000; Cell Signaling; 4970).
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... eIF2α 1:500 (Cell signaling #5324), p-eIF2α 1:500 (Cell signaling #3398) ...
• Vorinostat corrects cognitive and non-cognitive symptoms in a mouse model of fragile X syndrome

  Qi Ding, Xueting Wu, Xuan Li, Hongbing Wang, bioRxiv - Neuroscience 2020

  Quote: ... and H4 (Cell Signaling, 1:1000). The relative amount of loading was determined by β-actin ...
• Inhibition of mTOR during a postnatal critical sensitive window rescues deficits in GABAergic PV cell connectivity and social behavior caused by loss of TSC1

  Mayukh Choudhury, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-pAMPK (1:800, Cell Signaling), and anti-GAPDH (1:5000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... ULK1 (1:1000, Cell Signaling, #8054), p62 (1:2000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... FIP200 (1:1000, Cell Signaling, #12436), Atg101 (1:1000 ...
• Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation

  Emmanouela Kallergi, et al., bioRxiv - Neuroscience 2020

  Quote: ... Atg101 (1:1000, Cell Signaling, #13492), ULK1 (1:1000 ...