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3351 - 3400 of 10000+ citations for 8 BROMO 7 3 CHLOROPROPYL 1 3 DIMETHYL 2 3 6 7 TETRAHYDRO 1H PURINE 2 6 DIONE since 2019

• A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer

  Zinab O. Doha, et al., bioRxiv - Cancer Biology 2022

  Quote: HER2 (Cell Signaling #2242, 1:50); ERa (Millipore #04-227 ...
• The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin

  Colin Stok, et al., bioRxiv - Cancer Biology 2022

  Quote: ... γH2AX (Cell Signaling, 9718, 1:1000), RAD51 (GeneTex ...
• The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin

  Colin Stok, et al., bioRxiv - Cancer Biology 2022

  Quote: ... γH2AX (Cell Signaling, 9718, 1:1000), phospho-KAP1 (Bethyl ...
• A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer

  Zinab O. Doha, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TIM3 (Cell Signaling #83882, 1:200); EOMES (Abcam #ab183991,1:1000) ...
• Curvature Sensing and Membrane Remodeling of the VPS37A N-terminal Domain during Autophagy

  Yansheng Ye, et al., bioRxiv - Biochemistry 2022

  Quote: ... GFP (Cell Signaling, 2956, 1:1,000); MAP1LC3B (Novus ...
• Optogenetic Instruction of Cell Fate by Temporal Patterning of Mechanobiological Signals

  Rocío G. Sampayo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pSMAD1/5 (1:400, Cell Signaling), mCherry (1:1000 ...
• Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

  Cody A. Rutledge, et al., bioRxiv - Physiology 2022

  Quote: ... AMPK (1:1000, Cell Signaling, #2532), GAPDH (1:5000 ...
• Metformin preconditioning protects against myocardial stunning and preserves mitochondrial dynamics and protein translation in a mouse model of cardiac arrest

  Cody A. Rutledge, et al., bioRxiv - Physiology 2022

  Quote: ... DRP1 (1:1000, Cell Signaling, #5391), p-S6 (Ser240/244 ...
• Disruption of HIF1Α translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo

  Jill E Hunter, et al., bioRxiv - Cancer Biology 2022

  Quote: ... YB-1 (#4202, Cell Signaling Technologies), BNIP3L (#12396 ...
• MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

  Yadira M. Soto-Feliciano, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Axin1 (1:1000, Cell Signaling, #2074), β-actin (1:10000 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... BIM (1:1000; C34C5; Cell Signaling), FoxO1 (1:1000 ...
• p16^High senescence restricts totipotent potential during somatic cell reprogramming

  Bogdan B. Grigorash, et al., bioRxiv - Cell Biology 2022

  Quote: ... γH2Ax (Cell Signaling #9718; 1:1000), Nanog (Cell Signaling #8822 ...
• p16^High senescence restricts totipotent potential during somatic cell reprogramming

  Bogdan B. Grigorash, et al., bioRxiv - Cell Biology 2022

  Quote: ... Gata6 (Cell Signaling #5851, 1:500), Keratin 7 (Genetex #GTX110414 ...
• p16^High senescence restricts totipotent potential during somatic cell reprogramming

  Bogdan B. Grigorash, et al., bioRxiv - Cell Biology 2022

  Quote: ... Nanog (Cell Signaling #8822, 1:100), Desmin (Abcam #15200 ...
• The homeobox transcription factor DUXBL controls exit from totipotency

  Maria Vega-Sendino, et al., bioRxiv - Developmental Biology 2022

  Quote: ... HP1 (1:200, #2616, Cell Signaling), HA (1:500 ...
• Antagonistic H3K79me-H3K9ac crosstalk determines elongation at housekeeping genes to promote pluripotency

  Coral K. Wille, et al., bioRxiv - Developmental Biology 2022

  Quote: ... H3K27me3 (1:1000; Cell Signaling, 9733S), RNAPII RPB1 NTD D8L4Y (1:1000 ...
• Imbalanced Unfolded Protein Response Signaling Contributes to 1-Deoxysphingolipid Retinal Toxicity

  Jessica D. Rosarda, et al., bioRxiv - Cell Biology 2022

  Quote: ... ATF4 (1:200 Cell Signaling 11815) (Secondary antibodies ...
• Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines

  Simon Schwörer, et al., bioRxiv - Cell Biology 2022

  Quote: ... LDHA (1:1000, 2012S, Cell Signaling) and GFP (1:1000 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... AKT (1:2000; 40D4; Cell Signaling), phospho(Ser235/236)-S6 ribosomal protein (1:1000 ...
• P bodies coat germ granules to promote transgenerational gene silencing in C. elegans

  Zhenzhen Du, et al., bioRxiv - Cell Biology 2022

  Quote: ... HA (1:1000, Cell Signaling Technology) or tubulin (1:2000 ...
• GBP2 aggregates LPS and activates the caspase-4 inflammasome independent of the bacterial encapsulation factor GBP1

  Mary S. Dickinson, et al., bioRxiv - Immunology 2022

  Quote: ... GBP5 (Cell Signaling 67798, 1:5,000), GAPDH (Abcam ab9485 ...
• Exosome-derived lncRNA HOXA-AS3 promotes castration resistance and progression of prostate cancer via the miR-29b-3p/Mcl-1/STAT3 axis

  Jie Teng, et al., bioRxiv - Genomics 2022

  Quote: ... ab32539).GAPDH (1:800; Cell Signaling Technology) and β-actin (1:1000 ...
• A tissue injury repair pathway distinct but parallel to host pathogen defense

  Siqi Liu, et al., bioRxiv - Immunology 2022

  Quote: ... STAT3 (124H6, Cell Signaling, 1:1000), p-STAT3 (D3A7 ...
• A microbiota-derived metabolite instructs peripheral efferocytosis

  Pedro H. V. Saavedra, et al., bioRxiv - Immunology 2022

  Quote: ... H3K27me3 (Cell Signaling, 9733, 1:2500), H3K36me3 (Active Motif ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... eIF4G (1:200; rabbit, Cell Signaling,
• Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer’s disease

  Sarah Mustaly-Kalimi, et al., bioRxiv - Neuroscience 2022

  Quote: ... Lamp1 (1:500; Cell Signaling CS4H11)] diluted in 1X TBS 0.1% Triton-X + 1% goat serum for overnight at 4°C ...
• Deletion of transglutaminase 2 from astrocytes significantly improves their ability to promote neurite outgrowth on an inhibitory matrix

  Jacen Emerson, et al., bioRxiv - Neuroscience 2023

  Quote: ... Bassoon (1:200) (Cell Signaling #6897), and Homer (1:200 ...
• Eos promotes T_H2 differentiation by propagating the IL-2/STAT5 signaling pathway

  Jasmine A. Tuazon, et al., bioRxiv - Immunology 2022

  Quote: ... STAT5 (Cell Signaling, 94205S, 1:5000), STAT5B (1:5000 ...
• Microbial Metabolite Trimethylamine N-Oxide Promotes Campylobacter jejuni Infection by Escalating Intestinal Inflammation, Epithelial Damage, and Barrier Disruption

  Caitlyn B. Smith, et al., bioRxiv - Microbiology 2024

  Quote: ... zonula occludens-1 (Cell Signaling Technologies), zonula occludens-2 (ZO-2 ...
• Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

  Audrey Burban, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Notch1 (1:1000, Cell Signaling, #CST3608), Olig2 (1:2000 ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Tubulin (1:1000, Cell Signaling CS2146), Lamin A (1:1000 ...
• Co-Essentiality Analysis Identifies PRR12 as a Regulator of Cohesin and Genome Integrity

  Alexandra L. Nguyen, et al., bioRxiv - Cell Biology 2024

  Quote: ... SMC4 (1:500, Cell Signaling; D14E2), H3S10p (1:250 ...
• History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2022

  Quote: ... phospho-Akt (1:1000, Cell Signaling), total Akt (1:1000 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pTauThr231 (1:500, Cell Signaling), anti-Tau (46)(1:500 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pTauThr181 (1:500, Cell Signaling), anti-pTauSer214 (1:500 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pTauSer214 (1:500, Cell Signaling), anti-pTauThr231 (1:500 ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-AKT (1:1000, Cell Signaling), anti-pGSK3β (Ser9 ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... p38 (Cell Signaling, #8690, 1:1000), p-p38 (Cell Signaling ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... Akt (Cell Signaling, #9272, 1:1000), p-Akt Thr 308 (Cell Signaling ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... Jnk (Cell Signaling, #9258, 1:1000), p-Jnk (Cell Signaling ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... Pten (Cell Signaling, #9188, 1:1000), Sept8 (ProteinTech ...
• Pinch2 is a novel regulator of myelination in the Central Nervous System

  J Paes de Faria, et al., bioRxiv - Neuroscience 2022

  Quote: ... Erk (Cell Signaling, #9102, 1:1000), p-Erk (Cell Signaling ...
• Excessive fluid shear stress-mediated Klf4 leads to arteriovenous pathogenesis

  Kuheli Banerjee, et al., bioRxiv - Molecular Biology 2022

  Quote: ... CDK2 (#2546, 1:1000, Cell signaling), CDK6 (#3136 ...
• Excessive fluid shear stress-mediated Klf4 leads to arteriovenous pathogenesis

  Kuheli Banerjee, et al., bioRxiv - Molecular Biology 2022

  Quote: ... CDK6 (#3136, 1:1000, Cell signaling) and CDK4 (#12790 ...
• Excessive fluid shear stress-mediated Klf4 leads to arteriovenous pathogenesis

  Kuheli Banerjee, et al., bioRxiv - Molecular Biology 2022

  Quote: ... E2F1 (#3743, 1:1000, Cell signaling), CDK2 (#2546 ...
• PKC-alpha promotes phosphorylation of KRAS suppressing its oncogenic properties

  Tejashree Joglekar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-PARP-1 (Cell Signaling #9532); anti-p21 (Cell Signaling #2947) ...
• Deletion of TRPC6, an autism risk gene, induces hyperexcitability in cortical neurons derived from human pluripotent stem cells

  Kyung Chul Shin, et al., bioRxiv - Neuroscience 2022

  Quote: ... CTIP2 (Rabbit, 1:200, Cell signaling:), BRN2 (Rabbit ...
• CHK2 Regulates MUS81-EME2 Function in Response to Replication Stress and BRCA2 Deficiency

  Eva Malacaria, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-pS1981ATM (Cell signaling, 1:1000), anti-ATM (Cell signaling ...
• CHK2 Regulates MUS81-EME2 Function in Response to Replication Stress and BRCA2 Deficiency

  Eva Malacaria, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-HA (Cell signaling, 1:1000), anti-Cyclin A (Santa Cruz Biotechnology ...
• CHK2 Regulates MUS81-EME2 Function in Response to Replication Stress and BRCA2 Deficiency

  Eva Malacaria, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-ATM (Cell signaling, 1:1000), anti-HA (Cell signaling ...