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8001 - 8050 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation

  Nicholas M. Cronin, et al., bioRxiv - Cell Biology 2024

  Quote: ... monoclonal VE-Cadherin at 1:1000 (Cell Signaling; D87F2), monoclonal β-Actin at 1:1000 (Cell Signaling ...
• Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation

  Nicholas M. Cronin, et al., bioRxiv - Cell Biology 2024

  Quote: ... monoclonal AMPK-alpha at 1:1000 (Cell Signaling; 2532), monoclonal Ser-1177 phospho-eNOS at 1:500 (Cell Signaling ...
• ErbB2/HER2 expression level determines CDK4-inhibitor sensitivity and cyclin D1 and c-Myc dependency at the G1/S transition

  Ayaka Nagasato-Ichikawa, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-AKT (Thr308; 1:1000; Cell Signaling Technology; #2965), ERK (1:1000 ...
• Loss of SPNS1, a lysosomal transporter, in the nervous system causes dysmyelination and white matter dysplasia

  Yoshinobu Ichimura, et al., bioRxiv - Cell Biology 2024

  Quote: ... Antibodies against TFEB (4240, Cell Signaling Technology 1:200), LAMP-1 (AF4800 ...
• Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking

  Kelly H. Sokol, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Vinculin (Cell Signaling Technology 13901, clone E1E9V, 1:1000), β-actin (Cell Signaling Technology 3700 ...
• DNA damage causes ATM-dependent heterochromatin loss leading to nuclear softening, blebbing, and rupture

  Nebiyat Eskndir, et al., bioRxiv - Cell Biology 2024

  Quote: ... Lamin A/C 1:10,000 (4777, Cell Signaling Technologies), H3k9me2-3 1:400 (5327 ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-p-STING (Cell Signaling Technology, 19781S, 1:1000), anti-TBK1 (Proteintech ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-mouse IgG (Cell Signaling Technology, 7076S, 1:3000), anti-rabbit IgG (Cell Signaling Technology ...
• Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

  Andrew Hartley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ARID1A/BAF250A rabbit mAb (Cell Signaling, #12354, 1:100). For immunoprecipitation ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-p-TBK1 (Cell Signaling Technology, 5483S, 1:1000), anti-IRF3 (Proteintech ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-rabbit IgG (Cell Signaling Technology, 7074S, 1:3000) (Supplementary Table 3) ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-Tuberin/TSC2 (1:100, Cell Signaling 4308), rabbit anti-Hamartin/TSC1 (1:1000 ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-Hamartin/TSC1 (1:1000, Cell Signaling 6935), mouse anti-EGFR (1:50 ...
• Physiological role and mechanisms of action for a long noncoding haplotype region

  Hong Xue, et al., bioRxiv - Genetics 2024

  Quote: ... or Myosin IIb (1:200, 8824S, Cell Signaling Technology) primary antibodies were used ...
• Enhancing autophagy by redox regulation extends lifespan in Drosophila

  Claudia Lennicke, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-rabbit IgG (#7074, Cell Signaling Technology; 1:5,000). Blots were developed using standard ECL ...
• VGLL2 and TEAD1 fusion proteins drive YAP/TAZ-independent transcription and tumorigenesis by engaging p300

  Susu Guo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... YAP/TAZ (cat. 8418, 1:1000, Cell Signaling Technology), panTEAD (cat ...
• VGLL2 and TEAD1 fusion proteins drive YAP/TAZ-independent transcription and tumorigenesis by engaging p300

  Susu Guo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... V5-tag (cat. 13202, 1:1000, Cell Signaling Technology), p300 (cat ...
• Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage

  Roy Rabinowitz, et al., bioRxiv - Bioengineering 2024

  Quote: ... Antibodies used: p21 (1:1000, #2947 Cell Signaling Technologies) and GAPDH (1:1000 ...
• The complexity and dynamics of in organello translation assessed by high-resolution mitochondrial ribosome profiling

  Taisei Wakigawa, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-GAPDH (Cell Signaling Technology [CST], 2118, 1:1000), anti-TOMM20 (CST ...
• Novel Endogenous Engineering Platform for Robust Loading and Delivery of Functional mRNA by Extracellular Vesicles

  Antje M. Zickler, et al., bioRxiv - Bioengineering 2024

  Quote: ... rb-α-PEG10 (#77111, Cell Signaling Technology, 1:1000), ms-α-SDCBP (Syntenin ...
• Oncogenic Ras-driven Dorsal/NF-κB signaling contributes to tumorigenesis in a Drosophila carcinoma model

  Caroline Dillard, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-cleaved Dcp1 rabbit (1:100, Cell Signaling 9578), anti-phosphoJNK mouse (* 1:100 ...
• Alpha-synuclein aggregates are phosphatase resistant

  SG Choi, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-mouse HRP conjugate (dil. 1:6,000, Cell signaling), or anti-mouse IRDye 680RD (dil ...
• Purification of mitochondria from skeletal muscle tissue for transcriptomic analyses reveals localisation of nuclear-encoded non-coding RNAs

  Jessica Silver, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Citrate Synthase (Cell Signaling Technology #14309; 1:1000), anti-α-Tubulin (Cell Signaling Technology #3873 ...
• Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators

  Roberto Notario Manzano, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-EGFR (Cell Signaling ref: 4267, 1:1000), rabbit anti-CX43 (Sigma ref ...
• Purification of mitochondria from skeletal muscle tissue for transcriptomic analyses reveals localisation of nuclear-encoded non-coding RNAs

  Jessica Silver, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-α-Tubulin (Cell Signaling Technology #3873; 1:1000), anti-mitofilin (Abcam #ab110329 ...
• Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

  Alexander G. Sorets, et al., bioRxiv - Bioengineering 2024

  Quote: ... beta-actin (Clone 13E5, Cell signaling 4970, 1:2,000), GFAP (Clone D1F4Q ...
• Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

  Atsuki En, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-STING antibody (Cell Signaling, #13647, 1:500), and rabbit anti-GAPDH antibody (ABclonal ...
• Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

  Atsuki En, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-cGAS antibody (Cell Signaling, #31659, 1:500), rabbit anti-STING antibody (Cell Signaling ...
• Master corepressor inactivation through multivalent SLiM-induced polymerization mediated by the oncogene suppressor RAI2

  Nishit Goradia, et al., bioRxiv - Molecular Biology 2024

  Quote: ... EZH2 (D2C9, 1:125, Cell Signaling Technology, MA, USA) or H3K27me3 (C36B11 ...
• Turnover of PPP1R15A mRNA encoding GADD34 controls the molecular memory of the cellular integrated stress response

  Vera Magg, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Akt (Cell Signaling, Cat# 4691; 1:1,000; milk), anti-phospho-Akt (R&D systems ...
• Turnover of PPP1R15A mRNA encoding GADD34 controls the molecular memory of the cellular integrated stress response

  Vera Magg, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-p38 (Cell Signaling, Cat# 8690; 1:1,000 milk), anti-phospho-p38 (Cell Signaling ...
• Turnover of PPP1R15A mRNA encoding GADD34 controls the molecular memory of the cellular integrated stress response

  Vera Magg, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-eIF2α (Cell Signaling, Cat# 9722; 1:1,000; milk), anti-phospho-eIF2α (Cell Signaling ...
• Turnover of PPP1R15A mRNA encoding GADD34 controls the molecular memory of the cellular integrated stress response

  Vera Magg, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-phospho-p38 (Cell Signaling, 4511, 1:1,000; BSA), anti-Akt (Cell Signaling ...
• Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation

  Qin Ni, et al., bioRxiv - Biophysics 2024

  Quote: ... and anti-Ki-67 (Cell Signaling; 9129; 1:400). Secondary antibody ...
• Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling

  Yunxing Shi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-p-IRF3 (Cell Signaling Technology, 29047S#, 1:1000), anti-GAPDH (Proteintech ...
• Methyltransferase DNMT3B promotes colorectal cancer cell proliferation by inhibiting PLCG2

  Yong Ji, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PLCG2 (1:150; 5690, Cell Signaling Technology, Massachusetts, USA) and then with a biotin-conjugated secondary antibody (SA1050 ...
• CTNND2 regulation by the SRGAP2 protein family links human evolution to synaptic neoteny

  Nora Assendorp, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-Myc (Cell Signaling Technology #2276, 1:1,000), mouse anti-CTNND2 (Abcam #ab54578 ...
• Purification of mitochondria from skeletal muscle tissue for transcriptomic analyses reveals localisation of nuclear-encoded non-coding RNAs

  Jessica Silver, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-S6 RPL (Cell Signaling Technology #2217, 1:1000), anti-GM130 (BD Transduction Laboratories #610822 ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-STAT1 (D1K9Y) (Cell Signaling, #14994; 1:1,000), rabbit anti-phospho-STAT1 (D4A7 ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-MX1(D3W7I) (Cell Signaling, #37849, 1:1,000), rabbit anti-fibrillarin (Abcam ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-ATF4 (D4B8) (Cell Signaling, #11815; 1:1,000), rabbit anti-PERK (D11A8 ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-STAT2 (D9J7L) (Cell Signaling, #72604; 1:1,000), rabbit anti-phospho-STAT2 (D3P2P ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-IFIT1 (D2X9Z) (Cell Signaling, #14769; 1:1,000), rabbit anti-MX1(D3W7I ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-PERK (D11A8) (Cell Signaling, #5683; 1:1,000), rabbit anti-eIF2⍺ (D7D3)(Cell Signaling ...
• Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus

  Pheonah Badu, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-eIF2⍺ (D7D3)(Cell Signaling, #5324; 1:1,000), rabbit anti-p-eIF2⍺ (D9G8 ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-HER3/ErbB3 (1:1000, Cell Signaling 12708), rabbit anti-phospho-EGF receptor (Tyr845 ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-HER2/ErbB2 (1:1000, Cell Signaling 2165), rabbit anti-HER3/ErbB3 (1:1000 ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... Histone H2B (V119, Cell Signaling Technology, 8135, 1:1000), BRCA2 (Ab-1 ...
• Missense Mutant Gain-of-Function Causes Inverted Formin 2 (INF2)-Related Focal Segmental Glomerulosclerosis (FSGS)

  Balajikarthick Subramanian, et al., bioRxiv - Genetics 2024

  Quote: ... or HA (1:500) (2367; Cell Signaling Technology, MA). The membranes were then incubated with IRDye secondary antibodies and imaged using a Odyseey Clx Infrared system (LI-COR ...
• Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma

  Nicole M. Marsh, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:3000 rabbit MCU antibody (Cell Signaling Technology, 14997); 1:3000 rabbit MICU1 antibody (ABclonal ...