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7801 - 7850 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells

  Tan Dai Nguyen, et al., bioRxiv - Bioengineering 2023

  Quote: ... and SOX1 (1:500, 4194S, Cell Signaling Technology, USA). Cells were centrifuged and washed twice with PBS ...
• Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy

  Liying Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... CREB (1:1000, Rabbit, RRID:AB_10699020, Cell Signaling Technology, USA), p-CREB (1:1000 ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-pERM (Cell Signaling Technology #3726, 1:200), rabbit anti-Rab5 (Cell Signaling Technology #3547 ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Rab5 (Cell Signaling Technology #3547, 1:400). Images were acquired using a Leica SP8 Lightning Confocal DMI6000 microscope ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-pERM (Cell Signaling Technology #3726, 1:200). Cell death was determined using TUNEL (Cat ...
• Regulation of VEGFR2 and AKT signaling by Musashi-2 in lung cancer

  Igor Bychkov, et al., bioRxiv - Cell Biology 2023

  Quote: ... VEGFR2 (55B11, Rabbit, 1:50, Cell signaling, Cat #2479) at 4 °C in a humidified slide chamber ...
• The Novel Role of Midbody-Associated mRNAs in Regulating Abscission

  Trey Farmer, et al., bioRxiv - Cell Biology 2023

  Quote: ... Acetylated-Tubulin (Cell Signaling #D20G3, 1:500 for immunofluorescence), Acetylated-Tubulin (Millipore Sigma #T7451 ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Golgin-97 (Cell Signaling Technology, 13192; 1:400); anti-VDAC (Cell Signaling Technology ...
• BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation

  Samuel R. Witus, et al., bioRxiv - Biochemistry 2023

  Quote: ... Primary anti-HA antibody (3724S, Cell Signaling; 1:500) was incubated overnight at 4°C in 5% goat serum in PBS ...
• CRTC-1 balances histone trimethylation and acetylation to promote longevity

  Carlos G. Silva-García, et al., bioRxiv - Genetics 2023

  Quote: ... and rabbit α-H3 (1:1000, Cell Signaling 9715). The secondary antibody was α-rabbit IgG HRP-linked (1:1000 ...
• Loss of polarity regulators initiates gasdermin E mediated pyroptosis in human maternal fetal interface trophoblasts

  Khushali Patel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti β-actin (1:250; Cell Signaling Technologies; #8457); anti-EEA1 (1:50 ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Raptor (2280, Cell Signaling Technology, 2280, 1:400); anti−RagC (Cell Signaling Technology ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-phospho‒AMPKα (Thr172; Cell signaling, 2535, 1:500), anti-TFE3 (Sigma ...
• Liraglutide protects against diastolic dysfunction and improves ventricular protein translation

  Cody Rutledge, et al., bioRxiv - Physiology 2023

  Quote: ... p-4EBP1 (Thr37/46, 1:1000, Cell Signaling, #2855), 4EBP1 (1:1000 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Phospho-p38 (1:1000, D3F9, 4511T, Cell Signaling), anti-p38 (1:1000 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-EEA1 (1:1000, clone C45B10, 3288S, Cell Signaling), anti-LC3b (1:1000,clone D11,3868,Cell Signaling) ...
• Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

  Chunsong Yang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p-STAT1(Tyr701)(1:1,000, rabbit, Cell Signaling 9171), LAMIN A/C (1:40 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-EEA1 (1:200, clone C45B10, 3288S, Cell Signaling), anti-GFP (1:200 ...
• Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKD

  Yiming Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... polyubiquitin K48 (rabbit pAb, Cell Signaling; 4289; 1:1000), ENaCα (rabbit pAb ...
• Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels

  Victor Hugo Bustos, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... anti-p62 (rabbit polyclonal, 1:500; Cell Signaling Technology), anti-CK1γ2 (rabbit polyclonal ...
• Repair oligodendrocytes demyelinating and disintegrating damaged axons after injury

  Gianluigi Nocera, et al., bioRxiv - Neuroscience 2023

  Quote: ... c-Jun (Rabbit, 1:200, Cell signaling, 60A8, #9165), c-Jun (mouse ...
• Repair oligodendrocytes demyelinating and disintegrating damaged axons after injury

  Gianluigi Nocera, et al., bioRxiv - Neuroscience 2023

  Quote: ... c-Jun (Rabbit, 1:500, Cell signaling, 60A8, #9165), Phospho-c-Jun (Rabbit ...
• The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice

  Ugo Sardo, et al., bioRxiv - Physiology 2023

  Quote: ... goat anti-rabbit IgG (Cell signaling, 7074, 1/10000) or horse anti-mouse IgG (Cell signaling ...
• Predicting gene level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework

  Neha Cheemalavagu, et al., bioRxiv - Systems Biology 2023

  Quote: ... anti-pSTAT3 Y705 (Cell Signaling Technology 4113, 1:200), and anti-pSTAT1 Y701 (Cell Signaling Technology 9167 ...
• Mechanistic characterization of a Drosophila model of paraneoplastic nephrotic syndrome

  Jun Xu, et al., bioRxiv - Zoology 2023

  Quote: ... rabbit anti-ERK Antibody (Cell Signaling, 4695, 1:1000), rabbit phospho-ERK (Cell Signaling ...
• Ca²⁺/Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis

  Debarati Mukherjee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Actin (1:10000, 8H10D10, Catalog # 3700, Cell Signaling). Secondary antibodies used were HRP-conjugated anti-mouse IgG (1:5000 ...
• Pan-cancer analysis of the ion permeome reveals functional regulators of glioblastoma aggression

  Alexander T. Bahcheli, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and rabbit anti-GAPDH (1:3000, Cell Signaling #2118S). Experiments were performed in three biological replicates ...
• SLC15A4 controls endolysosomal TLR7-9 responses by recruiting the innate immune adaptor TASL

  Haobo Zhang, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit anti-HA (no. 3724, Cell Signaling, 1:1,000) and mouse anti-LAMP2 (sc-18822 ...
• Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance

  Cameron Geller, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or SMAD3 (Cell Signaling Technology catalog #9523S, 1:100) in 2% BSA/PBS solution and the appropriate fluorescently-conjugated secondary antibody (R&D Systems catalog #NL006 ...
• Deletion of smooth muscle O-GlcNAc transferase prevents development of atherosclerosis in western diet-fed hyperglycemic ApoE^-/- mice in vivo

  Saugat Khanal, et al., bioRxiv - Pathology 2023

  Quote: ... pERK and tERK (1:1000, Cell Signaling, Danvers, MA); O-GlcNAc (RL2 ...
• Primary cilia promote the differentiation of human neurons through the WNT signaling pathway

  Andrea Coschiera, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-PSD95 (Cell Signaling 2507; 1:100). Centrosome (centriole ...
• Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation

  Shiyi Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... and phospho-ERM (Rabbit, 1:250; #3726, Cell Signaling). Following primary incubation ...
• Loss of presenilin-1 in smooth muscle cells ameliorates elastin aortopathy

  Junichi Saito, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-HES1 (Cell Signaling Technology, 11988; 1:1000), rabbit anti-Ki67 (Invitrogen ...
• mRNA Location and Translation Rate Determine Protein Targeting to Dual Destinations

  Alexander N. Gasparski, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-GAPDH (1:2000; Cell Signaling cat# 2118L). Anti-rabbit and anti-mouse secondary antibodies from Li-Cor were used at 1:10,000 ...
• Stem cells tightly regulate dead cell clearance to maintain tissue fitness

  Katherine S Stewart, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-RARγ (D3A4) (Cell Signaling, 8965, 1:250), rabbit anti-MFGE8 (Invitrogen ...
• p90RSK2, a new MLCK, rescues contractility in myosin light chain kinase null smooth muscle

  Jaspreet Kalra, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Pyk2 phospho-Tyr402 (1:500) from Cell Signaling. For triple westerns proteins were separated on 1.5 mm thick ...
• The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism

  Adriana Marques-Carvalho, et al., bioRxiv - Cell Biology 2023

  Quote: ... Bax (1:1000, 2772, Cell Signaling, Danvers, MA, USA), denaturated form of OXPHOS complexes cocktail (1:1000 ...
• The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores

  Matteo Burigotto, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-53BP1 (Cell Signaling Technology, 4937, 1:500), mouse anti-cyclin A2 (Abcam ...
• Host genetic background regulates the capacity for anti-tumor antibody-dependent phagocytosis

  James E. Glassbrook, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and CD8α (1:400, tris, Cell Signaling Technology, 98941). Tumors were harvested ...
• NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma

  Eslam Katab, et al., bioRxiv - Cancer Biology 2023

  Quote: ... c-REL (1:1,000, rabbit, Cell Signaling Technology #4727), CUL1 (1:500 ...
• Senescent cells and macrophages cooperate through a multi-kinase signaling network to promote intestinal transformation in Drosophila

  Ishwaree Datta, Erdem Bangi, bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Dcp1(1:1000, Cell Signaling Technology #9578), mouse anti-β-gal (1:100 ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Myc tag (1:1,000, Cell Signaling Technology, Cat# 2276), V5 (1:1,000 ...
• Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function

  Veronica Jové, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-USP18 (D4E7) 1:25 (Cell Signaling, 4813S), and rabbit anti-Vinculin 1:300 (Abcam ...
• Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

  Lise Finotto, et al., bioRxiv - Cancer Biology 2023

  Quote: ... with anti-GAL1 (Cell Signaling Technology, 13888, 1:375) and anti-SOX2 (ThermoFisher Scientific ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Mek1/2 (1:1,000, Cell Signaling Technology, Cat# 9122), alpha-tubulin (Sigma ...
• Lack of mTORC2 signaling in CD11c⁺ myeloid cells inhibits their migration and ameliorates experimental colitis

  Aline Ignacio, et al., bioRxiv - Immunology 2023

  Quote: ... -pS6 (T389) (1:1.000, Cell Signaling Technology, MA, USA), -Claudin 2 (1:500) ...
• RSV infection does not induce EMT

  Sattya N. Talukdar, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit monoclonal (1:1000) E-cadherin (Cell Signaling Technologies), and rabbit monoclonal (1:1000 ...
• DISTINCT ROLES OF VIRAL US3 AND UL13 PROTEIN KINASES IN HERPES VIRUS SIMPLEX TYPE 1 (HSV-1) NUCLEAR EGRESS

  Masoudeh Masoud Bahnamiri, Richard J. Roller, bioRxiv - Microbiology 2023

  Quote: ... rabbit anti-phospho-Akt substrates (1:500) (Cell Signaling), mouse monoclonal anti-actin (Sigma-Aldrich) ...
• PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

  Nicolas Gordon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-CDC2 (Tyr15) (1:1500, Cell Signaling Technology 9111S), CDC2 p34 (1:200 ...
• Wnt5a-Ror2 signaling activates p62-Nrf2 axis in reactive astrocytes after brain injury

  Mitsuharu Endo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-Wnt5a (Cell Signaling Technology, 2530, 1:1000), mouse anti-α-Tubulin (Sigma-Aldrich ...