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701 - 750 of 1183 citations for 2 Pyridinesulfonic acid methyl ester since 2020

• Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation

  Raphael Trenker, et al., bioRxiv - Biochemistry 2024

  Quote: ... rabbit anti-phospho-p44/42 MAPK (Erk1/2) (Cell Signaling, 9101, 1:1000), mouse anti-AKT (Cell Signaling ...
• Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

  Lauren Podmore, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-p44/42 MAPK (Erk1/2) (T202/Y204) (p-ERK; Cell Signaling #9101), and Ki67 (Lab Vision #RM-9106-S1 ...
• An atlas of epithelial cell states and plasticity in lung adenocarcinoma

  Guangchun Han, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phosphorylated p44/42 MAPK (ERK1/2, rabbit, Cell Signaling Technology, 9101, 1:2000), Phosphorylated S6 Ribosomal protein (Ser 235/236 ...
• Optogenetic Regulation of EphA1 RTK Activation and Signaling

  Anna I Wurz, Kevin Zheng, Robert M. Hughes, bioRxiv - Synthetic Biology 2024

  Quote: ... total ERK using p44/42 MAPK (ERK1/2) rabbit Ig (Cell Signaling Technologies). Blots were washed with TBST 3x for 5 min and incubated in corresponding secondary antibody for 1 hour room temperature ...
• VEGF counteracts shear stress-determined arterial fate specification during capillary remodeling

  Dongying Chen, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell signaling Technology, #9101) were diluted in blocking buffer ...
• The Microtubule Severing Protein UNC-45A Counteracts the Microtubule Straightening Effects of Taxol

  Asumi Hoshino, et al., bioRxiv - Cell Biology 2023

  Quote: ... phospho-myosin light chain 2 (Ser 19) antibody (Cell signaling, #3671, 1:1000), and monoclonal anti-myosin clone MY-21 (Sigma ...
• ACE1 knockout in neurons selectively dysregulates the hippocampal renin angiotensin system and causes vascular loss

  Sohee Jeon, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-p-p44/42 MAPK (p-Erk1/2) (#CS9101, Cell Signaling Technology), rabbit anti-p44/42 (Erk1/2 ...
• RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells

  Vasanth Siruvallur Murali, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Thr18/Ser19 Phospho-Myosin Light Chain 2 1:1000(Cell Signaling Technology, 3674), GLUT1 1:1000 (Cell Signaling Technology,12939S) ...
• Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

  Mehrnaz Mehrabipour, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-ERK(1/2) (1:1000; #9102, Cell Signaling, Frankfurt am Main, Germany); anti-p-ERK(1/2 ...
• ALK signaling drives tumorigenicity and chemoresistance of pancreatic ductal adenocarcinoma cells

  Beatriz Parejo-Alonso, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK 1/2 (1:3000) (all from Cell Signaling Technology, Danvers, MA, USA), pERK 1/2 (T202-Y204 ...
• Inverse Agonist Activity of Angiotensin II Receptor Blocker Is Crucial for Prevention of Aortic Aneurysm Formation in Marfan Syndrome

  Hiroki Yagi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... rabbit polyclonal anti-phosphorylated ERK1/2 (Thr202/Tyr204) antibody (Cell Signaling Technology, #9101), rabbit polyclonal anti-ERK1/2 antibody (Cell Signaling Technology ...
• New Features Surrounding the Cdc42-Ste20 Module that Regulates MAP Kinase Signaling in Yeast

  Beatriz González, et al., bioRxiv - Biochemistry 2023

  Quote: ... Polyclonal rabbit phospho-p44/42 MAPK (Erk1/2, Cat#3102, Cell Signaling Technology), and p38 (Cat#9211 ...
• Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

  Christine Chiasson-MacKenzie, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-p44/42 (ERK1/2) rabbit pAb (1:1000; 9102, Cell Signaling Technology); anti-ErbB2 rabbit pAb (IF ...
• Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis

  Rachel Warren, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-phosporylated-Mst1(Thr183)/2(Thr180) (1:200; 3681; RRID:AB_330269; Cell Signaling), goat anti-Scgb1a1 (1:200 ...
• Protection of high-frequency low-intensity pulsed electric fields and BDNF for SH-SY5Y cells against hydrogen peroxide-induced cell damage

  Guan-Bo Lin, et al., bioRxiv - Neuroscience 2023

  Quote: ... Bcl-2-associated X protein (Bax) (Cell Signaling Technology, Inc., Danvers, MA, USA), and GAPDH (GeneTex ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (#4370, Cell signaling, 1:1000), p44/42 MAPK (Erk1/2 ...
• Multiomics mapping and characterization of cellular senescence in aging human skeletal muscle uncovers a novel senotherapeutic for sarcopenia

  Yang Li, et al., bioRxiv - Cell Biology 2024

  Quote: ... cells were incubated with 2 μg of JUNB antibody (Cell Signaling Technology #3753) or H3K27ac (Cell Signaling Technology #8173 ...
• Therapeutic expression of RAS Degrader RRSP in Pancreatic Cancer via Nanocarrier-mediated mRNA delivery

  Taylor E. Escher, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-p44/42 MAPK (ERK1/2; Cell Signaling Technology, catalog no. 4696, RRID:AB_390780), and anti-HB-EGF (Abcam ...
• Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors

  Surbhi Dhingra, et al., bioRxiv - Neuroscience 2024

  Quote: ... 2 ug of an antibody (host: rabbit, Cat. No.- 12698, Cell Signaling Technology) was added to 40 µL pre-equilibrated Protein A agarose (Thermo Scientific ...
• Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation

  Qin Ni, et al., bioRxiv - Biophysics 2024

  Quote: ... anti-Phospho-p44/42 MAPK (p-ERK1/2; Cell Signaling; 9101; 1:1000), anti-p44/42 MAPK (ERK1/2 ...
• SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness

  Yiyang Zhou, et al., bioRxiv - Microbiology 2024

  Quote: ... Cells were permeabilized and incubated with SARS-CoV-2 nucleocapsid antibody (Cell Signaling) followed by Alexa FluorTM 555-conjugated α-mouse secondary antibody (Invitrogen) ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... Cells were incubated with 2 µg rabbit anti-HA antibody (Cell Signaling C29F4) overnight at 4°C on orbital shaker ...
• Urban wastewater contains a functional human antibody repertoire of mucosal origin

  Sean Stephenson, et al., bioRxiv - Immunology 2024

  Quote: ... and SARS-CoV-2 Spike Protein Serological IgA ELISA Kit (Cell Signaling, #58873C). Samples were tested with dilutions ranging from 1-125x ...
• Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant

  Nghi D. P. Dang, et al., bioRxiv - Neuroscience 2024

  Quote: ... stained for 2-3 days with the total ERK antibody (Cell Signaling, #4696) and phospho-Erk antibody (Cell Signaling #4370) ...
• Reverse engineering of the pattern recognition receptor FLS2 reveals key design principles of broader recognition spectra against evading flg22 epitopes

  Songyuan Zhang, et al., bioRxiv - Plant Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell Signaling Technology, #9101) was used to detect phosphorylated MAPKs.
• Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity

  Chen-Yi Liao, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-human phospho-Erk1/2 (Thr202/Tyr204) (1:1000; 9101, Cell Signaling), mouse-anti-human FN (1:5000 ...
• Spectrin coordinates cortical actomyosin organization and differentiation essential for a functional epithelial barrier

  Arad Soffer, et al., bioRxiv - Cell Biology 2024

  Quote: ... phospho-Myosin Light Chain 2 (Thr18/Ser19) (IF 1:100, Cell Signaling #3674); occludin (IF 1:400 ...
• Inhibition of glutaminase elicits senolysis in therapy-induced senescent melanoma cells

  Justin Kim, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and anti-p44/42 MAPK (Erk1/2) (137F5) obtained from Cell Signaling Technology. All primary antibodies were diluted in TBST with 5% BSA to the manufacturer’s recommended concentrations ...
• A maternally inherited Chromosomal Passenger Complex regulates germ plasm ribonucleoparticle aggregation in Zebrafish

  Cara E. Moravec, Francisco Pelegri, bioRxiv - Developmental Biology 2024

  Quote: ... Rabbit anti-phospho-Myosin Light Chain 2 (1∶50, Cell Signaling Technology 3671L), Rabbit anti-AurB (1∶100)(43) ...
• Wnt pathway modulation is required to correctly execute multiple independent cellular dynamic programs during cranial neural tube closure

  Amber Huffine Bogart, Eric R. Brooks, bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-phospho-Myosin Regulatory Light Chain 2 (1:100, Cell Signaling 3674), rat anti-VANGL2 (1:100 ...
• Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis

  Samantha C. Schwager, et al., bioRxiv - Cancer Biology 2021

  Quote: Primary antibodies used were rabbit anti-flotillin-2 (3436; Cell Signaling Technology, Danvers, MA), mouse anti-α smooth muscle actin (M0851 ...
• Replication Study: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

  Steven Pelech, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-MEK1/2 (total MEK) [clone 47E6] (Cell Signaling Technology, cat# 9126; RRID:AB_331778) at 1:1000 dilution in 5% w/v nonfat dry milk/TBST ...
• The laminin-keratin link shields the nucleus from mechanical deformation and signalling

  Zanetta Kechagia, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit Phospho-Myosin Light Chain 2 (Thr18/Ser19) 1:500 (Cell Signaling, Cat# 3674), rabbit anti-Cytokeratin 8 [EP1628Y] 1:2000 (Abcam ...
• S-Palmitoylation-Dependent Regulation of Cardiomyocyte Rac1 Signaling Activity and Cardiac Hypertrophy

  Matthew J. Brody, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-extracellular signal-regulated kinase (ERK) 1/2 (Cell Signaling Technology, #4370, 1:500), ERK1/2 (Cell Signaling Technology ...
• Vascular Endothelial Growth Factor as an Immediate-Early Activator of UV-induced Skin Injury

  Stella P. Hartono, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Slides were immunostained using antibodies that recognize total VEGFR-2 (#2479, Cell Signaling Technology) and phosphorylation of VEGFR-2 at Y1175 (#2478 ...
• Mechanically active integrins direct cytotoxic secretion at the immune synapse

  Mitchell S. Wang, et al., bioRxiv - Immunology 2021

  Quote: ... Cell Signaling Technology) and pErk1/2 (Phospho-Thr202/ Tyr204; clone D13.14.4E; Cell Signaling Technology).
• The DCC receptor regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

  Laura Morcom, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-phospho p44/42 Mapk (or Erk1/2; 1:250; 9101, Cell Signaling), rabbit anti-Sox9 (1:500 ...
• Listeria monocytogenes utilizes the ClpP1/2 proteolytic machinery for fine-tuned substrate degradation under heat stress

  Dóra Balogh, et al., bioRxiv - Biochemistry 2021

  Quote: ... 2 mg/mL) or 4 μL isotype control (2.5 mg/mL, Cell Signaling Technology) were used ...
• Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification

  Francesca M. Aloisio, Diane L. Barber, bioRxiv - Cell Biology 2021

  Quote: ... Phospho-p44/42 MAPK Erk1/2 Thr202/Tyr204 (1:1000; #9101; Cell Signaling Technology), Grhl2 (1:1000 ...
• Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification

  Francesca M. Aloisio, Diane L. Barber, bioRxiv - Cell Biology 2021

  Quote: ... Phospho-Myosin Light Chain 2 Thr18/Ser19 E2J8F (1:1000; #95777; Cell Signaling Technology), ERK 1 C-16 (1:1000 ...
• SUMO Modifies GβL and Mediates mTOR Signaling

  Sophia Louise Lucille Park, et al., bioRxiv - Biochemistry 2020

  Quote: ... SUMO-1 (4930) and SUMO-2/3 (4971) were obtained from Cell Signaling Technology. 6x-His tag Antibody (MA1-125 21315 ...
• Manipulation of IRE1-dependent MAPK signaling by a Vibrio agonist-antagonist effector pair

  Nicole J. De Nisco, et al., bioRxiv - Microbiology 2020

  Quote: ... For MEK1/2 inhibition qPCR experiments MEFs were incubated with 10μM U0126 (Cell Signaling) or 10μM DMSO (vehicle ...
• The Mechanism of Neurite Outgrowth Induction by Novel Synthetic Retinobenzoic Acids

  Yang Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... and then the membranes were re-probed with anti-ERK1/2 (Cell Signaling Technology), or anti-mTOR (Cell Signaling Technology ...
• α-actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization

  Amlan Barai, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-myosin light chain 2 (phosphor- Ser19) rabbit monoclonal antibody (Cat #3671, Cell Signaling)) diluted in PBS overnight at 4°C ...
• FLT3-ITD transduces autonomous growth signals during its biosynthetic trafficking in acute myelogenous leukemia cells

  Kouhei Yamawaki, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (137F5) and ERK[pT202/pY204] (E10) from Cell Signaling Technology (Danvers, MA); TfR (ab84036) ...
• Aberrant mechanosensitive signaling underlies activation of vascular endothelial xanthine oxidoreductase that promotes aortic aneurysm formation in Marfan syndrome

  Hiroki Yagi, et al., bioRxiv - Pathology 2022

  Quote: ... rabbit polyclonal anti-phosphorylated ERK1/2 antibody (Thr202/Tyr 204) (Cell Signaling Technology, #9101), rabbit monoclonal anti- phosphorylated p38 MAPK antibody (Thr180/Tyr182 ...
• Deletion of the microglial transmembrane immune signaling adaptor TYROBP ameliorates Huntington’s disease mouse phenotype

  Jordi Creus-Muncunill, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:1000, #9101, Cell Signaling), anti-p44/42 MAPK (Erk1/2 ...
• Autophagy Increases Occludin Levels to Enhance Intestinal Paracellular Tight Junction Barrier

  Kushal Saha, et al., bioRxiv - Cell Biology 2022

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) and anti-LAMP2 (Cell Signaling Technologies 3251S ...
• AMP-kinase mediates adaptation of glioblastoma cells to conditions of the tumour microenvironment

  Nadja I. Lorenz, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ACC and AMPKα1/2 (#3661, #2535, #3661, #2532, Cell Signaling Technology, Danvers, MA, USA), AMPKα2 (#18167-1 ...
• Cell-surface PD-L1 expression identifies a sub-population of distal epithelial cells enriched in idiopathic pulmonary fibrosis

  Negah Ahmadvand, et al., bioRxiv - Cell Biology 2022

  Quote: ... F(ab’)2 Fragment (Alexa Fluor® 555 Conjugate Cell Signaling Technologies 1:1000).