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6001 - 6050 of 10000+ citations for 7 Methyl 1 5 dioxo 1 2 3 5 tetrahydro indolizine 6 carbonitrile since 2019

• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Chk1 (1:2000; Cat# 2345, Cell Signaling), anti-cyclin A (1:1000 ...
• H3.1^Cys96 oxidation by mitochondrial ROS promotes chromatin remodeling, breast cancer progression to metastasis and multi-drug resistance

  Flavio R. Palma, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and GAPDH (1:1000, Cell Signaling Technology, #97166) followed by species-specific antibodies incubation (IRDye Goat anti-Mouse ...
• A cell surface code mediates tissue-intrinsic defense against aberrant cells in epithelia

  Friedericke Fischer, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Dcp1 (1:400, Cell Signaling-9578S), rat anti-E-cadherin (1:50 ...
• SIN3 acts in distinct complexes to regulate the germline transcriptional program in C. elegans

  M. Caron, et al., bioRxiv - Genetics 2023

  Quote: ... mouse anti-H3 (#14269 Cell Signaling, 1:500), Rat anti-RNA Pol II (#04-1571 Millipore ...
• Chromatin remodeling enzyme Snf2h is essential for retinal cell proliferation and photoreceptor maintenance

  Andrea Kuzelova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-CENP-A (Cell Signaling, 1:500), rabbit anti-Rxrγ (Santa Cruz ...
• Integrating lipid metabolism, pheromone production and perception by Fruitless and Hepatocyte nuclear factor 4

  Jie Sun, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-HA (Cell Signaling Technology, #3724S, 1: 500), anti-HNF4 guinea pig polyclonal antibody (1:100 ...
• The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis

  Bianca M. Lupan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... TBR1 (Cell Signaling Technology, 49,661 S, 1:1000), LHX2 (Millipore ...
• Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity

  Pilar Rivero-Ríos, et al., bioRxiv - Cell Biology 2023

  Quote: ... EEA1 mouse mAb (1:200, 48453, Cell Signaling), vGLUT1 guinea pig pAb (1:2000 ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... AKT (Cell Signaling Technology, Cat.No.9272S, 1:1000), phospho-ERK1/2 (Cell Signaling Technology ...
• Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation

  Eun Hye Park, et al., bioRxiv - Neuroscience 2023

  Quote: ... 4EBP1 (Cell Signaling Technology, Cat.No.9452S, 1:1000). Actin (Sigma ...
• A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped mice

  Matthew R. Johnson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1:1000 β-tubulin (mAb #86298, Cell Signaling). Secondary antibodies ...
• Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells

  Tan Dai Nguyen, et al., bioRxiv - Bioengineering 2023

  Quote: ... SOX1 (1:500, 4194S, Cell Signaling Technology, USA), and HOXB4 (1:200 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Rab11 (1:50, D4F5, 5589, Cell Signaling), anti-Lamp1(1:800 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Rab5(1:200, C8B1, 3547, Cell Signaling), anti-Rab11 (1:50 ...
• Critical role of PCYT2 in muscle health and aging

  Domagoj Cikes, et al., bioRxiv - Genetics 2023

  Quote: ... anti-ClC3 (#9661S, Cell Signaling, DE, 1:100), anti-B220 (#550286 ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-VDAC (Cell Signaling Technology; 4866, 1:400), anti-PMP70 (Sigma ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-calreticulin (Cell Signaling Technology, 12238, 1:400), anti-β-actin (Sigma-Aldrich ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti−RagC (Cell Signaling Technology, 5466, 1:500); rabbit anti-phospho-AKT (Ser473 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-LC3b (1:1000,clone D11,3868,Cell Signaling), anti-Rab7 (1:1000 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Rab7 (1:1000, D95F2, 9367, Cell Signaling), anti-Rab5 (1:1000 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Rab5 (1:1000, C8B1, 3547, Cell Signaling). Secondary antibodies ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-p38 (1:1000, D13E1, 8690T, Cell Signaling), anti-Phospho-p44/42 (ERK1/2 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-IκBα (1:1000, L35A5, 4814, Cell Signaling), anti-Borcs5 (1:500 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Rab7 (1:100, D95F2, 9367, Cell Signaling), anti-Rab5(1:200 ...
• Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

  Janine M. DeBlasi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... NRF2 (Cell Signaling Technologies, D1Z9C, RRID:AB_2715528, 1:1000), NQO1 (Sigma Aldrich ...
• Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

  Janine M. DeBlasi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ki-67 (Cell Signaling Technology, RRID:AB_2620142, 1:200), and Cleaved Caspase-3 (Cell Signaling Technology ...
• Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids

  Rebecca Sebastian, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-SOX2 (1:500 Cell Signaling 3697S), rabbit anti-HOPX (1:500 ...
• Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy

  Martin L. Read, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Na,K-ATPase (1:500; Cell Signaling Technology); PICALM (1:1000 ...
• A cross-species proteomic map reveals neoteny of human synapse development

  Li Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Phospho-CFL (Cell Signaling Technology, 3311S, 1:1000), CFL (Cell Signaling Technology ...
• A cross-species proteomic map reveals neoteny of human synapse development

  Li Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Phospho-PAK (Cell Signaling Technology, 2606S, 1:1,000), PAK (Cell Signaling Technology ...
• Acute resistance exercise induces mitophagy and mitophagomes on subsarcolemmal clefts in human skeletal muscle: Focus on BNIP3L/NIX40 as a mitophagy flux marker

  F. Díaz-Castro, et al., bioRxiv - Physiology 2023

  Quote: ... p-mTOR (1:1000, 2971, Cell Signaling Technology), p-AMPK (1:1000 ...
• Acute resistance exercise induces mitophagy and mitophagomes on subsarcolemmal clefts in human skeletal muscle: Focus on BNIP3L/NIX40 as a mitophagy flux marker

  F. Díaz-Castro, et al., bioRxiv - Physiology 2023

  Quote: ... p-AMPK (1:1000, 2531, Cell Signaling Technology), p62 (1:2000 ...
• Mechanistic characterization of a Drosophila model of paraneoplastic nephrotic syndrome

  Jun Xu, et al., bioRxiv - Zoology 2023

  Quote: ... rabbit phospho-JNK (Cell Signaling, 4668T, 1:1000), rabbit anti-ERK Antibody (Cell Signaling ...
• Mechanistic characterization of a Drosophila model of paraneoplastic nephrotic syndrome

  Jun Xu, et al., bioRxiv - Zoology 2023

  Quote: ... rabbit phospho-ERK (Cell Signaling, 4370, 1:1000). After washing with TBST ...
• Ca²⁺/Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis

  Debarati Mukherjee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-PDE5 (1:1000, Catalog #2395, Cell Signaling); anti-PDE1C ...
• Ca²⁺/Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis

  Debarati Mukherjee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-AMPKα (1:500, Catalog # 2532, Cell Signaling); anti-phospho-VASP (Ser239 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... B-actin (cat# 8H10D10, Cell Signaling, 1:1500) and B-tubulin (cat# MA5 16308 ...
• Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection

  Geoffrey T. Norris, et al., bioRxiv - Immunology 2023

  Quote: ... Rabbit anti-NeuN (1:2000; D3S3I; Cell Signaling), Chicken anti-NeuN (1:300 ...
• The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells

  Kévin Leguay, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Ezrin (1:1000, Cell Signaling #3145), rabbit anti-Radixin (1:1000 ...
• The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells

  Kévin Leguay, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Moesin (1:1000, Cell Signaling #3150), mouse anti-Actin (1:5000 ...
• The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells

  Kévin Leguay, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit-anti ERM (1:1000, Cell Signaling #3142), rabbit anti-Ezrin (1:1000 ...
• PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma

  Rafik Boudra, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p-p130 (Y165) (Cell Signaling, 4015, 1:1000), p130 (Cell Signaling ...
• PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma

  Rafik Boudra, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p-FAK (Y397) (Cell Signaling, 8556, 1:1000), ACTIN (Thermofisher Scientific ...
• Regulation of lipolysis by 14-3-3 proteins on human adipocyte lipid droplets

  Qin Yang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-HSL (Cell Signaling Technology, 1:1000 dilution), anti-ATGL (Cell Signaling Technology ...
• Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation

  Shiyi Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... phospho-ERM (Rabbit, 1:500; #3141, Cell Signaling), ERM (Rabbit ...
• Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation

  Shiyi Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... phospho-ERM (Rabbit, 1:500; #3141, Cell Signaling), Sox9 (Rabbit ...
• Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation

  Shiyi Wang, et al., bioRxiv - Neuroscience 2023

  Quote: ... and GEHPYRIN (Rabbit, 1:1000; #14304S, Cell Signaling). Following the primary incubation ...
• Tissue-specific vulnerability to apoptosis in Machado-Joseph disease

  Ana F. Ferreira, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Bax (1:500; #2772, Cell Signaling,) mouse anti-p53 (1:1000 ...
• Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness

  Zhiqing Huang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Akt (1:1000, Cell Signaling, Cat#9272), and anti-GADPH (1:2000 ...
• Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

  Neha Zutshi, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Villin-1 (Cat# 2369, Cell Signaling Technology). Membranes were washed 3X in TBS-T ...