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701 - 750 of 1389 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Identification of a myofibroblast differentiation program during neonatal lung development

  Yongjun Yin, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-MEOX2 (1:200, NBP2-30647, Novus Biological). Alexa-488 ...
• Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation

  Pei Yee Tey, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-CD63 (Novus Biologicals, NBP2-42225SS, WB 1:500), anti-HA (Novus Biologicals ...
• Rejuvenation of aged oocyte through exposure to young follicular microenvironment

  HaiYang Wang, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti–CDX2 (NB100-2136, Novus Biologicals; 1:100), rabbit anti– RFP (# 600-401-379 ...
• Dynamic fibroblast-immune interactions shape wound healing after brain injury

  Nathan A. Ewing-Crystal, et al., bioRxiv - Immunology 2024

  Quote: ... rat anti-Periostin (345613, Novus Biologicals MAB3548, 1:200), rat anti-ICAM1 (YN1/1.7.4 ...
• Paraoxonase-like APMAP maintains endoplasmic reticulum-associated lipid and lipoprotein homeostasis

  Blessy Paul, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-APMAP (1:150; Novus biologicals; NBP2-01716), rabbit anti-GFP (1:200 ...
• The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores

  Matteo Burigotto, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-53BP1 (Novus Biologicals, NB100-304, 1:500), donkey anti-rabbit AlexaFluor 488 (Thermo Fisher ...
• A newly-recognized population of residual neural crest cells in the adult leptomeninges is re-activated for vascular repair

  Yoshihiko Nakamura, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Col3a1 antibody (1:100, NB600-594, Novus Biologicals), anti-Cped1 antibody (1:100 ...
• Calorie Restriction activates a gastric Notch-FOXO1 pathway to expand Ghrelin cells

  Wendy M. McKimpson, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5HT (Novus Biologicals, cat. no. NB120-16007, 1:50), Gastrin (Abcam ...
• Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

  Jumee Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-BrdU (Novus Biologicals, NBP2-14890, 1:200), CD44 (BioLegend ...
• Multiple cancer types rapidly escape from multiple MAPK inhibitors to generate mutagenesis-prone subpopulations

  Timothy E. Hoffman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... FANCD2 rabbit pAb (1:500, Novus Biologicals #100-182); Polκ mouse mAb (1:500 ...
• Proneural genes form a combinatorial code to diversify neocortical neural progenitor cells

  Alexandra Moffat, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouseIgG1-anti-Bcl11b (Novus Biologicals #NB100-2600, 1:500), rabbitIgG-anti-Neurod2 (Abcam #ab104430 ...
• Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

  Janos Groh, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-GAL3 (1:1,000, NBP3-03252; Novus Biologicals); rat anti-GAL3 (1:300 ...
• Paridiprubart inhibits TLR4-dependant NF-κB activation by multiple pathogens

  Ramy Malty, et al., bioRxiv - Immunology 2023

  Quote: ... Human HMGB1/HMG-1 ELISA (Novus Biologicals, NBP2-62766) was performed as described in manufacturer’s instructions ...
• Hypoxia regulate developmental coronary angiogenesis potentially through VEGFR2- and SOX17-mediated signaling

  Halie E. Vitali, et al., bioRxiv - Developmental Biology 2023

  Quote: ... HIF-1α (1:100, Cat: NB100-479, Novus Biologicals), SOX17 (1:100 ...
• Androgen exposure impairs neutrophil maturation and function within the infected kidney

  Teri N. Hreha, et al., bioRxiv - Immunology 2023

  Quote: ... Ly6C-PE/Cy5.5 (1:200, Novus Biologicals #NB100-65413PECY55), CD101-AlexaFluor 647 (1:100 ...
• An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

  Simone Caielli, et al., bioRxiv - Immunology 2023

  Quote: 1 µg/mL of purified human MxA (Novus Biological) was incubated with or without 100 ng/mL of recombinant human mIL-1b (R&D ...
• Nuclear envelope assembly relies on CHMP-7 in the absence of BAF-LEM-mediated hole closure

  Sarah R. Barger, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1 μg/mL rabbit α-LEM-2 (Novus Biologicals), 1 μg/mL rabbit α-CHMP-7 (Shankar et al. ...
• Functional synapses between small cell lung cancer and glutamatergic neurons

  Anna Schmitt, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-GAP43 (1:2000, Novus Biologicals, #NB300-143), rabbit anti-PGP9.5 (1:2000 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ZRANB3 (1:1000; Cat# NBP2-93301, Novus Biologicals), anti-phospho-Akt (Ser473 ...
• The RNA-binding protein Adad1 is necessary for germ cell maintenance and meiosis in zebrafish

  Kazi Nazrul Islam, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit Sycp3 at 1:200 (NB300-232SS, Novus Biologicals), mouse BrdU at 1:200 (5292S ...
• Motor nerves direct the development of the sympathetic nervous system

  Alek Erickson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... sheep anti–TH (1:2000, Novus Biologicals, #NB300-110), chicken anti-TH (1:500 ...
• A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped mice

  Matthew R. Johnson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... chicken anti-GFP (Novus Biologicals # NB100-1614, 1:200), or rabbit anti-Krt14 (BioLegend #905301 ...
• Pancreatic loss of Mig6 alters murine endocrine cell fate and protects functional beta cell mass in an STZ-induced model of diabetes

  Brandon M. Bauer, et al., bioRxiv - Physiology 2023

  Quote: ... rabbit anti ALDH1A3 (Novus Biologicals NBP2-15339, 1:500), rabbit anti MAFA (Bethyl Laboratories BLR067G ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-GAP-43 (1:300; Novus Biologicals, NB300-143), anti-HGS (1:200 ...
• APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1

  Terumasa Ikeda, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit anti-A3H (Novus Biologicals, NBP1-91682, 1:5,000): mouse anti-Vif (NARP ...
• GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

  Liang Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-GTPBP10 (1:500, NBP1-85055, Novus Biologicals), mouse anti-HSP60 (1:20000 ...
• Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome

  Suchira Gallage, et al., bioRxiv - Physiology 2023

  Quote: ... 1:500 (clone M5/114.15.2, Novus Biologicals, NBP1-43312); anti-CD68 ...
• NK cells contribute to resistance to anti-PD1 therapy in immune-excluded melanomas

  Ewout Landeloos, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD8 (Novus Biologicals cat. no NB200-578; 1:200), NKp46 (R&D Systems cat ...
• PAH DEFICIENT PATHOLOGY IN HUMANIZED c.1066-11G>A PHENYLKETONURIA MICE

  Ainhoa Martínez-Pizarro, et al., bioRxiv - Pathology 2023

  Quote: ... and p62/SQSTM1 (1:5000, Novus biologicals, H00008878-M01). Secondary antibodies were horse anti-mouse (1:2000 ...
• Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover

  Michael J. Podolsky, et al., bioRxiv - Cell Biology 2023

  Quote: ... SEL1L (1:2,000; Novus Biologicals: NBP2-93746; ABCAM: ab78298), collagen I (1:2,000 ...
• The ability of the LIMD1 and TRIP6 LIM domains to bind to f-actin under strain is critical for their tension dependent localization to adherens junctions and association with the Hippo pathway kinase LATS1

  Samriddha Ray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti - LIMD1 (1:500, Novus biologicals, NBP2-56448), rabbit anti α-E-Catenin (1:500 ...
• NK cells contribute to resistance to anti-PD1 therapy in immune-excluded melanomas

  Ewout Landeloos, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD45 (Novus Biologicals cat. no NB100-77417SS; 1:400) and S100 (Dako cat ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-53BP1 (Novus biological NB100-305, 1:1,000) and mouse anti-biotin (Jackson ImmunoResearch cat.no ...
• Border-forming wound repair astrocytes

  Timothy M. O’Shea, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-HA (1:800, NB600-362, Novus Biologicals); rabbit anti-H2-Ab1 (1:200 ...
• Nerve injury converts Schwann cells in a persisting repair state in human neuroma tissue

  Stefanie Deininger, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-ATF3 (rabbit, 1:500, Novus biologicals, NBP1-85816).
• The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size

  Shicong Xie, et al., bioRxiv - Cell Biology 2024

  Quote: ... 53BP1 (Novus Biologicals #NB100-304, monoclonal rabbit 1:200); Keratin 10 (Biolegends #19054 ...
• Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH

  Dhanya Thamaraparambil Jayaram, et al., bioRxiv - Cell Biology 2024

  Quote: Human FLVCR (Novus Biologicals, #NB100-1481; dilution 1:1000), PGRMC2 (Santa Cruz ...
• Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis

  Matthew J. Seasock, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse anti-γH2AX (1:200, Novus Biological, NB100-74435), Rabbit anti-CLDN4 (1:200 ...
• Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis

  Matthew J. Seasock, et al., bioRxiv - Cell Biology 2024

  Quote: ... Rabbit anti-BACH1 (1:200, Novus Biological, NBP2-55113), Mouse anti-γH2AX (1:200 ...
• Cytoplasmic mRNA capping enzyme is regulated by hypoxia inducible factor HIF1α and controls stability of the target lncRNAs during hypoxia

  Safirul Islam, Chandrama Mukherjee, bioRxiv - Molecular Biology 2024

  Quote: ... 1:2000 mouse anti-GAPDH (Novus Biologicals, cat#2D4A7); 1:2000 rabbit anti-CA9 (Cloud-clone Crop ...
• JUNB O-GlcNAcylation-mediated promoter accessibility of metabolic genes modulates distinct epithelial lineage in pulmonary fibrosis

  Marie-Therese Bammert, et al., bioRxiv - Cell Biology 2024

  Quote: ... rat anti-SCGB1A1 (Novus Biological, #MAB4218-SP; 1:50); rabbit anti-KRT5 (Cell Signaling ...
• Deep Visual Proteomics advances human colon organoid models by revealing a switch to an in vivo-like phenotype upon xenotransplantation

  Frederik Post, et al., bioRxiv - Cell Biology 2024

  Quote: ... Pan-Laminin-AF647 (Novus Biologicals NB300-144AF647, 1:100).
• Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia

  Meaghan M. Broman, et al., bioRxiv - Immunology 2024

  Quote: ... at 1:100 and Granzyme K (polyclonal, Novus Biologicals) at 1:50 for 60 minutes the rinsed twice with staining buffer ...
• Dysregulation of cholesterol and bile acid homeostasis across the gut-liver axis following Cryptosporidium intestinal infection

  Shuhong Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-ABCG8 (Novus Biologicals, catalogue no. 1B10A5, 1:1000), anti-SLC10A2 (Abcam ...
• Histone deacetylase 5 in prelimbic prefrontal cortex limits context-associated cocaine seeking

  Sarah M. Barry, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-mCherry (NBP2-25157 Novus Biologicals, rabbit, 1:1000), anti-Flag (50-165-7385 Sigma Aldrich ...
• Epigenetic modulation of NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection

  Lakmini S. Premadasa, et al., bioRxiv - Pathology 2024

  Quote: ... p-MLKL(Thr357) (Novus Biologicals: MAB91871, 1:200 dilution), p-MLKL(Ser358 ...
• High-throughput differentiation of human blood vessel organoids reveals overlapping and distinct functions of the cerebral cavernous malformation proteins

  Dariush Skowronek, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and collagen IV (Novus Biologicals, #NB120-6586, 1:100), anti-Mouse IgG Fluor 350 (Thermo Fisher Scientific ...
• Site of breast cancer metastasis is independent of single nutrient levels

  Keene L. Abbott, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PYCRL (Novus Biologicals, NBP2-03337, clone OTI1B12, 1:1000), PYCRL (ABclonal ...
• A hollow fiber membrane-based liver organoid-on-a-chip model for examining drug metabolism and transport

  Adam Myszczyszyn, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-Villin (1:50, Novus Biologicals, NBP1-85335) and rabbit anti-NTCP (1:50 ...
• Orexinergic projections to substantia innominata mediate arousal and analgesia

  Xuaner Xiang, et al., bioRxiv - Neuroscience 2024

  Quote: ... chicken anti-mCherry (1:400, NBP2-25158, Novus Biologicals). Secondary ...