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851 - 900 of 1389 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult Mice

  Wai Lydia Tai, et al., bioRxiv - Neuroscience 2023

  Quote: ... and mouse anti-DNMT3a (1:100, Novus Biologicals, NB120-13888SS). Staining for anti-DNMT3a required 2N HCl treatment for 30 min at 37°C followed by neutralization with 0.1M Trish-HCl (pH 8.3 ...
• Top-down control of flight by a non-canonical cortico-amygdala pathway

  Chandrashekhar D. Borkar, et al., bioRxiv - Neuroscience 2023

  Quote: ... chicken anti-GFP (1:2000, NB100-1614, Novus Biologicals, USA), rabbit anti-cFos (1:1000 ...
• Liver size is predetermined in the neonate by adding lobules at the periphery

  D. Berfin Azizoglu, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and rabbit anti-Lyve1 (Novus Biologicals, NB600-1008, 1:500).
• Spatially resolved single-cell analysis uncovers protein kinase Cδ-expressing microglia with anti-tumor activity in glioblastoma

  Reza Mirzaei, et al., bioRxiv - Immunology 2023

  Quote: ... and gp91-phox (Novus Biologicals, NBP1-41012, 1:100 dilution). After primary antibody incubation ...
• Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2023

  Quote: ... stained with sulfatase 1 (Novus Biologicals, Cat# NBP231584, RRID: AB_2916043) or sulfatase 2 (Abcam ...
• Adaptive epigenetic regulation of neuronal metabolism by a mitochondrial redox signal

  Marius W. Baeken, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-SLC6A3 (DAT) (NBP2-22164, Novus Biologicals, 1:100). Secondary antibodies ...
• A universal influenza mRNA vaccine candidate boosts T-cell responses and reduces zoonotic influenza virus disease in ferrets

  Koen van de Ven, et al., bioRxiv - Immunology 2022

  Quote: ... and DNase I (1 mg/ml, Novus Biologicals, Centennial, CO) for 60 minutes at 37 °C while rotating ...
• Quisinostat is a brain-penetrant radiosensitizer in glioblastoma

  Costanza Lo Cascio, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and mouse anti-human Nestin (1:500; Novus Biologicals, 10C2). The following day ...
• Cytoplasmic nucleoporin foci are stress-sensitive, non-essential condensates in C. elegans

  Laura Thomas, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-OLLAS-L2 (1:50, Novus Biologicals cat # NBP1-06713). Secondary antibodies were diluted as follows ...
• Regulation of excitatory presynaptic activity by Ambra1 protein determines neuronal networks in sex-dimorphic manner

  Anes Ju, et al., bioRxiv - Neuroscience 2023

  Quote: ... and MAP2 (1:500, chicken polyclonal, NB300-213, Novus biologicals) diluted in blocking solution for overnight at 4°C ...
• The conserved AAA-ATPase PCH-2 distributes its regulation of meiotic prophase events by remodeling multiple meiotic HORMADs in C. elegans

  Anna E. Russo, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti- RAD-51 1:250 (Novus Biologicals, Littleton, CO), guinea pig anti-DSB-1 1:250 [49] ...
• Cross-species proteomic and microRNA comparison of extracellular vesicles in human milk, cow’s milk, and infant formula products: moving towards next generation infant formula products

  Natalie P. Turner, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-CD81 (1:1000, Rabbit polyclonal (Novus Biologicals (Invitro technologies), Melbourne ...
• Cross-species proteomic and microRNA comparison of extracellular vesicles in human milk, cow’s milk, and infant formula products: moving towards next generation infant formula products

  Natalie P. Turner, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-CD9 (1:1000, Mouse monoclonal (Novus Biologicals (Invitro technologies), Melbourne ...
• FBH1 deficiency sensitizes cells to WEE1 inhibition by promoting mitotic catastrophe

  Lucy Jennings, et al., bioRxiv - Cell Biology 2023

  Quote: ... Tubulin antibodies was from Novus Biologicals (NB100-690, 1: 1000).
• Aging shapes infection profiles of influenza A virus and SARS-CoV-2 in human lung slices

  Melanie Brügger, et al., bioRxiv - Microbiology 2024

  Quote: ... pro-surfactant protein C (pro-SFTPC, Novus Biologicals, 1:800), IAV nucleoprotein (NP ...
• Perfusion-Independent Tissue Hypoxia in Cardiac Hypertrophy in Mice Measured by ⁶⁴Cu-CTS PET Imaging

  Friedrich Baark, et al., bioRxiv - Bioengineering 2024

  Quote: ... Blots were probed for HIF1α (NB100, 1:500; Novus Biologicals) with β-actin as a loading control with HRP-linked anti-rabbit IgG secondary antibody (1:10,000 ...
• Monocytes Mobilized by Gut Neurons Remodel the Enteric Nervous System

  Sravya Kurapati, et al., bioRxiv - Immunology 2024

  Quote: ... CD31 (stains endothelial cells, 1:200, clone MEC7.46, Novus Biologicals) and MHC Class II (MHCII ...
• FcγR- and CD9-dependent synapse engulfing microglia in the thalamus drives cognitive impairment following cortical brain injury

  Ken Matoba, et al., bioRxiv - Immunology 2024

  Quote: ... rat monoclonal anti-CD68 (1:2,000; Novus Biologicals, #NBP2-33337), mouse monoclonal anti-TNF-α (1:100 ...
• Oligodendrocyte precursor cells exacerbate acute CNS inflammation via macrophage and T cell activation in a mouse model of multiple sclerosis

  Kana Ohashi, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-IL17 (NBP1-76337, rabbit IgG, 1:150; Novus Biologicals), anti-MHC class II (556999 ...
• The proneurogenic and microglial modulatory properties of botulinum toxin in the hippocampus of aging experimental mice

  Jerly Helan Mary Joseph, et al., bioRxiv - Neuroscience 2024

  Quote: ... Dylight 594 (Novus Biologicals NBP1-72732DL594, USA; 1:500 dilution) for 24 hours at 4 °C ...
• SARS-CoV-2 Omicron Envelope T9I adaptation confers resistance to autophagy

  Susanne Klute, et al., bioRxiv - Microbiology 2024

  Quote: ... mouse StrepII Tag Antibody (1:450; Novus Biologicals, #NBP2-43735). PLA probes and reagents used ...
• Neuronal identity control at the resolution of a single transcription factor isoform

  Natalie Smolin, et al., bioRxiv - Neuroscience 2024

  Quote: ... rat anti-DYDDDDK (1:200, Novus Biologicals, RRID: NBP1-06712SS), Alexa Fluor 647 goat anti-mouse (1:400 ...
• A hollow fiber membrane-based liver organoid-on-a-chip model for examining drug metabolism and transport

  Adam Myszczyszyn, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... and rabbit anti-NTCP (1:50, Novus Biologicals, NBP1-60109). After that ...
• A toolbox for ablating excitatory and inhibitory synapses

  Aida Bareghamyan, et al., bioRxiv - Neuroscience 2024

  Quote: ... chicken anti myc (1:1000, Novus Biologicals cat. # NB600-334). Secondary antibodies used were the following from Thermo Fisher Scientific at 1:1000 ...
• Glial scar formation by reactive astrocytes derived from oligodendrocyte progenitor cells after closed-head injury

  Hinata Matsuda, et al., bioRxiv - Neuroscience 2024

  Quote: ... chicken anti-Nestin (1:1000; Novus Biologicals, Centennial, CO. USA), rabbit andti-NG2 (1:200 ...
• KIF2A maintains cytokinesis in mouse embryonic stem cells by stabilising intercellular bridge microtubules

  Lieke Stockmann, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-KIF2A (Novus Biologicals, NB500-180, WB 1:1000), rabbit anti-MKLP1 (Abcam ...
• Identification of transcriptome-wide cobalt chloride-induced hypoxia-responsive long noncoding RNAs regulated by cytoplasmic mRNA capping enzyme

  Pinaki Ghosh, Safirul Islam, Chandrama Mukherjee, bioRxiv - Molecular Biology 2024

  Quote: ... 1:2000 mouse anti-GAPDH (Novus Biologicals, cat no# 2D4A7), 1:2000 rabbit anti-CA9 (Cloud-clone Corp ...
• Aquaporin-4 mis-localization slows glymphatic clearance of α-synuclein and promotes α-synuclein pathology and aggregate propagation

  Molly Braun, et al., bioRxiv - Neuroscience 2024

  Quote: ... and goat anti-Iba1 (1:200, Novus Biologicals NB100-1028). All secondary antibodies for immunofluorescence were generated in donkey ...
• Loss of Zmiz1 in mice leads to impaired cortical development and autistic-like behaviors

  K C Rajan, et al., bioRxiv - Neuroscience 2024

  Quote: ... BRDU (Novus Biologicals, NBP2-14890, 1:200, or Abcam, ab142567), CUX1 (ProteinTech 11733-1-AP ...
• Lymphatic endothelial cell-targeting lipid nanoparticles delivering VEGFC mRNA improve lymphatic function after injury

  Eleftheria Michalaki, et al., bioRxiv - Bioengineering 2024

  Quote: ... MHCII (BV650, 1:1500, NBP2-00462; Novus Biologicals, Littleton, CO), (x ...
• Secreted cytokines from inflammatory macrophages modulate sex differences in valvular interstitial cells on hydrogel biomaterials

  Nicole E. Félix Vélez, et al., bioRxiv - Bioengineering 2024

  Quote: ... methylated lysine (MeK, 1:350, Novus Biologicals, Cat. No. NB600824), and acetylated lysine (AcK ...
• Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women

  Neil Carleton, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and Ki-67 (Novus Biologicals, NB600-1252, 1:100 dilution).
• CRL4^DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication

  Anoop Kumar Yadav, et al., bioRxiv - Cell Biology 2024

  Quote: ... Strep II Tag (mouse, Novus Biologicals, NBP2-43735, 1:1,000), γH2AX (Ser139 ...
• NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress

  Ramchandra V Amnekar, et al., bioRxiv - Cell Biology 2024

  Quote: ... Anti-WNK4: NB600-284 (Novus Biologicals, rabbit polyclonal, 1:2000). Anti-HA ...
• Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3^-/y rat model of autism

  Natasha J Anstey, et al., bioRxiv - Neuroscience 2020

  Quote: ... before incubation with primary antibodies (anti-NLGN3 C-terminus, Synaptic Systems, 1:1000, RRID: AB_2619816.; anti-NLGN3 N-terminus, Novus Biologicals, 1:1000, RRID: AB_11027178) in blocking buffer with 0.01% sodium azide for 10 minutes at room temperature ...
• Perfusion bioreactor culture of adipose-derived stromal cells on decellularized adipose tissue scaffolds enhances in vivo regeneration

  Tim Tian Y. Han, Lauren E. Flynn, bioRxiv - Bioengineering 2020

  Quote: ... Sections were then incubated with rabbit anti-Ki-67 antibody (1:100 dilution) or mouse anti-HIF-1α antibody (Novus Biologicals, Oakville, Canada; 1:100 dilution) overnight at 4°C ...
• Skeletal muscle-derived Human Mesenchymal Stem Cells: influence of different culture conditions on proliferative and myogenic capabilities

  Stefano Testa, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells are incubated with the primary antibody anti-myosin heavy chain (MF20, mouse monoclonal, DHSB, diluted 1:2) or anti-ki67 (rabbit polyclonal, Novus Biologicals #NB110-89717, diluted 1:200) for 1 h ...
• Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts

  Ramona Jühlen, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-DOK7 (1:50; NBP2-02073; Novus Biologicals, Abingdon, UK), mouse anti-NUP88 (1:500 ...
• Protein disulphide isomerase (PDI) is protective against several types of DNA damage, including that induced by amyotrophic lateral sclerosis-associated mutant TDP-43 in neuronal cells/ in vitro models

  Sina Shadfar, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-γ-H2AX (1:500, Novus Biologicals, NB-100-384), or rabbit anti-53BP1 (1:500 ...
• Daam1 negatively regulates USP10 activity

  Andrew T. Phillips, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 1:300 rabbit-anti-G3BP2 (Novus Biologicals; Cat # NBP1-82977). Cultures were incubated in primary antibody solution at 4°C overnight ...
• Mitophagy mediates beige to white transition of human primary subcutaneous adipocytes ex vivo

  Attila Vámos, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-p62 (1:5000, Novus Biologicals, Centennial, CO, USA, NBP1-49956), anti-LC3 (1:2000 ...
• The antimicrobial peptide cathelicidin is critical for the development of Th17 responses in severe inflammatory disease

  Katie J Smith, et al., bioRxiv - Immunology 2022

  Quote: ... peripheral node addressin (MECA-79, Novus Biologicals, #NB100- 77673SS, 1:100) and Iba1 (goat polyclonal ...
• Enhancing mitochondrial activity in neurons protects against neurodegeneration in CNS inflammation

  Sina C. Rosenkranz, et al., bioRxiv - Neuroscience 2020

  Quote: ... PGC-1α (PGC-1α, rabbit, 1:100; Novus Biologicals; RRID: AB_1522118) and FLAG sequence (FLAG ...
• Meningeal dendritic cells-astrocytes interactions elevate the kynurenine metabolic pathway to sustain neuropathic pain

  Alexandre G. Maganin, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-KMO 1:200 (# NBP1-44263, Novus Biologicals, Littleton, Colorado, USA), a mouse monoclonal antibody against IDO-1 (# sc365086 ...
• Tethered NOS-3, a nematode Nanos RNA-binding protein, enhances reporter expression and mRNA stability

  Jonathan Doenier, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-V5 (1:1000, Novus Biologicals, Centennial, CO, #NB600-381), mouse anti-FLAG (1:1000 ...
• Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism

  Eric E. Ewan, et al., bioRxiv - Neuroscience 2020

  Quote: ... Nuclear expression of ATF3 (Novus Biologicals, Cat # NBP1-85816, 1:250) and Jun (Cell Signaling ...
• Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs

  Priyanka Patel, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Stathmin-2/SCG10 (1:500; Novus Biologicals, NBP1-49461). Stathmin-2/SCG10 immunofluorescence was used to detect regenerating mouse sciatic nerve axons (Shin et al. ...
• MORPHIOUS: A Machine Learning Workflow to Naively Detect the Activation of Microglia and Astrocytes

  Joseph Silburt, Isabelle Aubert, bioRxiv - Neuroscience 2020

  Quote: ... goat anti-mouse Gfap (Novus Biological, cat: NB100-53809; 1:2000), rabbit anti-Tgf1β (Abcam ...
• Irisin stimulates the release of CXCL1 from differentiating human subcutaneous and deep-neck derived adipocytes via upregulation of NFκB pathway

  Abhirup Shaw, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-ß-actin (1:5000, A2066, Novus Biologicals, CO, USA). HRP-conjugated goat anti-rabbit (1:10,000 ...
• The Fragile X Mental Retardation Protein protects the lung from xenobiotic stress by facilitating the Integrated Stress Response

  Deblina Sain Basu, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti- γ-H2AX (Novus biological, USA, NB100-384, 1:1000), mouse anti-Cyp2f2 (Santa Cruz ...