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901 - 950 of 10000+ citations for Flap endonuclease 1 FEN 1 Human since 2019

• The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging

  Erna Raja, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse anti-K10 (1:100, BioLegend, 904301, or 1:100, Abcam, ab9026), guinea pig anti-K31 (1:100 ...
• Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages

  Megan Rowton, et al., bioRxiv - Developmental Biology 2020

  Quote: ... GLI3 (1:1,000; R&D AF3690) and GAPDH (1:10,000; Abcam ab8245). Pixel density for GLI1/3 was then computed ...
• Nucleolin is expressed in human fetal brain development and reactivated in human glial brain tumors regulating angiogenesis and vascular metabolism

  Marc Schwab, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-PFKFB3 (1:100, abcam, rabbit anti-CPT1a (1:500, abcam), and rabbit andti-TIGAR (1:200 ...
• Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer’s Disease

  Dominic I. Javonillo, et al., bioRxiv - Neuroscience 2021

  Quote: ... lysosome-associated membrane protein 1 (LAMP1; 1:200; AB25245; Abcam, Cambridge, CA), human tau (HT7 ...
• A noble TGFβ biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

  Han-Soo Kim, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... blocked with 1% BSA and incubated with anti-CD14 (1:500, Abcam), anti-Myd88 (1:500 ...
• A Trem2*R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques

  Kristine M. Tran, et al., bioRxiv - Neuroscience 2022

  Quote: ... lysosome- associated membrane protein 1 (LAMP1; 1:200; AB25245; Abcam, Cambridge, CA), neurofilament light chain (NfL ...
• Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat

  Richard M. Hooy, et al., bioRxiv - Cell Biology 2022

  Quote: ... and anti-GAPDH (1:10000 in TBST, RT 1 hr, Abcam ab9485). Blots were then incubated with IRDye 800/680 conjugated antibodies (1:10000 in 5% milk TBST ...
• Thalamo-hippocampal pathway regulates incidental memory load in mice

  G. Torromino, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-glutamate receptor 1 (AMPA subtype) antibody (1:500; ab31232, Abcam) and anti-β-actin (1:5000 ...
• Hyaluronic acid particle hydrogels decrease cerebral atrophy and promote pro-reparative astrocyte/axonal infiltration in the core after ischemic stroke

  Elias Sideris, et al., bioRxiv - Bioengineering 2019

  Quote: ... for astrocytes and Glut-1 (Glucose Transporter-1, Abcam, Cambridge, MA, USA) for endothelial cells at 1:100 dilution in PBS with 0.3% triton and 10% donkey serum were added and incubated overnight at 4°C ...
• Regulation of human development by ubiquitin chain editing of chromatin remodelers

  David Beck, et al., bioRxiv - Genetics 2020

  Quote: ... anti-FOXG1 (ab18259, abcam, 1:1000 in IB, 1:100 in IF), anti-ARID1A (#12354 ...
• Single-cell genomic atlas of great ape cerebral organoids uncovers human-specific features of brain development

  Sabina Kanton, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-SATB2 (rabbit, 1:500, Abcam, Ab92446; mouse, 1:500, Abcam, Ab51502), anti-Tbr2 (mouse ...
• Single-cell genomic atlas of great ape cerebral organoids uncovers human-specific features of brain development

  Sabina Kanton, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-SATB2 (rabbit, 1:500, Abcam, Ab92446; mouse, 1:500, Abcam, Ab51502), anti-Tbr2 (mouse ...
• BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

  Drake Edwards, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or ChIP experiments: BRD4 N-terminus (1:1000WB, 1:1000IF, ab128874, Abcam); BRD2 (1:500WB ...
• C1q/CTRP1 exerts neuroprotective effects in TBI rats by regulating inflammation and autophagy

  Ming Pei, et al., bioRxiv - Pathology 2020

  Quote: ... and later incubated with rabbit anti-Beclin-1 (1:4000; Abcam, America), rabbit anti-LC3-II (1:2000 ...
• NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

  Carolina Marques, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, #9102, 1:1000; Abcam #ab17942, 1:1000), p-MEK (S217/221 ...
• The master energy homeostasis regulator PGC-1α couples transcriptional co-activation and mRNA nuclear export

  Simeon R. Mihaylov, et al., bioRxiv - Molecular Biology 2021

  Quote: ... UAP56/DDX39B [1:2000] (custom generated51) and THOC1 [1:1000] (Abcam ab131268) antibodies were detected using HRP-conjugated rabbit secondary antibody (Promega) ...
• Loss of function mutation of mouse Snap29 on a mixed genetic background phenocopy abnormalities found in CEDNIK and 22q11.2 Deletion Syndrome patients

  Vafa Keser, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-BrdU antibody (Abcam, ab6326, 1:100 in 1% goat serum/PBS), was incubated for 4°C overnight on each section ...
• V-ATPase is a universal regulator of LC3 associated phagocytosis and non-canonical autophagy

  Kirsty M. Hooper, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit monoclonal anti-ATP6V1A (ab199326, Abcam, WB 1:2000, IF 1:250), mouse monoclonal anti-ATP6V0d1 (ab56441 ...
• Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization

  Frédérique Vernel-Pauillac, et al., bioRxiv - Immunology 2020

  Quote: ... or IgG2c antibodies (all from Abcam, 1/5000 or 1/10000 diluted), added to the plates and incubated at RT for 1 h ...
• The selective estrogen receptor modulator tamoxifen protects against subtle cognitive decline and early markers of injury twenty-four hours after hippocampal silent infarct

  Caitlin A. Finney, et al., bioRxiv - Neuroscience 2020

  Quote: ... ionized calcium binding adaptor molecule 1 (Iba1; 1:1000; AB9722; Abcam, UK), cleaved caspase-3 (1:1000 ...
• SBT-272 improves TDP-43 pathology in the ALS motor cortex by modulating mitochondrial integrity, motility, and function

  Mukesh Gautam, et al., bioRxiv - Neuroscience 2022

  Quote: Antibodies used were: anti-GFP (1:1000, Invitrogen; or 1:1000, Abcam), anti-CHCHD3 (1:200 ...
• Physical confinement promotes mesenchymal trans-differentiation of invading transformed cells in vivo

  Teresa Zulueta-Coarasa, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse α-N-cadherin (BD Biosciences, 1:100 and Abcam, 1:100). Embryos were incubated with appropriate secondary antibodies (goat α-chicken-AlexaFluor-488 ...
• Oncogenic STIL-mediated loss of BRCA1 functionality causes DNA damage and centrosome amplification

  Srishti Sanghi, Priyanka Singh, bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-STIL antibody (Abcam#ab89314, 1:50 IF, 1:2000 WB), rabbit anti-ubiquitin antibody (Abcam#ab134953 ...
• Sensory progenitors influence patterning of the mammalian auditory sensory epithelium

  Caryl A. Young, Emily Burt, Vidhya Munnamalai, bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-SOX2 (1:500, ab97959, Lot# GR3244869-1,Abcam, Cambridge, UK), rabbit anti-Myosin VI (1:500 ...
• Porphyromonas gingivalis fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion

  Angélica Díaz-Basabe, et al., bioRxiv - Immunology 2023

  Quote: ... Akt 1/2/3 (1:500, Ab-179463, Abcam Cambridge, United Kingdom). Membranes were detected with peroxidase conjugated secondary antibodies (Agilent Technologies ...
• Core-N-glycans are atypically abundant at the neuronal surface and regulate glutamate receptor signaling

  Chun-Lei Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-GluA2 (IB, Abcam, 1:2000; IF, Synaptic systems, 1:1000)) ...
• Core-N-glycans are atypically abundant at the neuronal surface and regulate glutamate receptor signaling

  Chun-Lei Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-GluA1 (IB, Abcam, 1: 2000; IF, Synaptic Systems, 1:1000), rabbit anti-GluA2 (IB ...
• Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

  Hélène Lasolle, et al., bioRxiv - Cancer Biology 2023

  Quote: ... cells were also stained using primary Nkx2-1 antibody (1:100; Abcam) and donkey anti-rabbit IgG Cy3-conjugated (1:300 ...
• SART1 localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly

  Hideki Yokoyama, et al., bioRxiv - Cell Biology 2023

  Quote: ... SART1 #1 (Ms, Abcam, IF 3 μg/ml, WB 1 μg/ml), and SART1 #2 (Ms ...
• The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome

  Tara A. Gleeson, et al., bioRxiv - Immunology 2024

  Quote: ... rabbit-anti-mouse capase-1 p10 (1/1000 dilution; EPR16883, Abcam, ab179515), mouse-anti-mouse NLRP3 (1/1000 dilution ...
• Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB

  Bertha Osei, et al., bioRxiv - Biochemistry 2024

  Quote: ... Antibodies used were rabbit anti-HELB (Abcam: ab202141, 1:10,000-1:5,000), rabbit anti-RPA70 (Cell Signaling 2267S ...
• Synthesis of arbitrary interference patterns using a single galvanometric mirror, and its application to Structured Illumination Microscopy

  Ke Guo, et al., bioRxiv - Bioengineering 2024

  Quote: ... 100 μl of 1 μl in 1 ml phalloidin-iFluor 488 (Abcam) with 1% BSA was added and left for 90 minutes ...
• Behavioral and Neuroanatomical Investigation of Attention Deficit Hyperactivity Disorder Pathogenesis in Juvenile Spontaneously Hypertensive Rats

  Aysegul Gungor Aydin, Esat Adiguzel, bioRxiv - Neuroscience 2023

  Quote: ... and 1:1000 chicken polyclonal anti-TH (Abcam, Cat# AB76442, 1:1000), 0.05% NaN3 ...
• Temporal Coordination of the Transcription Factor Response to H₂O₂ stress

  Elizabeth Jose, et al., bioRxiv - Cell Biology 2023

  Quote: ... Recombinant Anti-Peroxiredoxin 1/PAG antibody [EPR5433] (ab109498) (1:1000) from Abcam and actin (Sigma ...
• Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment

  Lana Frankle, et al., bioRxiv - Neuroscience 2023

  Quote: ... at 1:40 or Emp1 at 1:100 (rabbit host, abcam, ab202975)in PBS.
• Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

  Elena Marchesan, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-GRASP65 (1:1000) and anti-Parkin (1:1000) were from Abcam; Alexa 488- ...
• Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)

  Rachel Battaglia, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Lamin B1 (Abcam ab16048, IF 1:10,000, WB 1:10,000), mouse anti-Nestin (Thermo Fisher Scientific ...
• Runx1 regulates critical factors that control uterine angiogenesis and trophoblast differentiation during placental development

  Athilakshmi Kannan, et al., bioRxiv - Physiology 2023

  Quote: ... platelet/endothelial cell adhesion molecule 1 (PECAM1/CD31, 1:250, Abcam, ab124432), placental lactogen 1 (PL1 ...
• Microglia facilitate and stabilize the response to general anesthesia

  Yang He, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-c-Fos (1:1000, Abcam, Cat#: ab190289, Lot: GR3367372-1), and rabbit anti-P2Y12 (1:500 ...
• FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma

  Katherine Gillis, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Slides were stained with antibodies to NKX2-1 (1:2000, Abcam EP1584Y), GFP (1:200 CST 2956S ...
• Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging

  Vanitha Nithianandam, et al., bioRxiv - Neuroscience 2023

  Quote: ... GABARAP (1:1,000, endogenous Drosophila Atg8a, E1J4E, Cell Signaling; 1:200, Abcam), LC3B (1:200 ...
• RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds

  Bin Fu, et al., bioRxiv - Biophysics 2023

  Quote: ... anti-phosphorated α-synuclein (ab184674, Abcam, 1:500; ab59264, Abcam, 1:200) ...
• RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds

  Bin Fu, et al., bioRxiv - Biophysics 2023

  Quote: ... anti-phosphorated α-synuclein (ab184674, Abcam, 1:500; ab59264, Abcam, 1:200) ...
• Inhibition of human immunodeficiency virus (HIV-1) infectivity by expression of poorly or broadly neutralizing antibodies against Env in virus-producing cells

  Qian Wang, et al., bioRxiv - Microbiology 2023

  Quote: ... 1:5000 rabbit anti-HIV-1 Gag p55/p24/p17 Ab (Abcam), mouse anti-gapdh Ab (Millipore) ...
• PLK4 homodimerization is required for CEP152 centrosome localization and spindle organization

  Harshita Kasera, Priyanka Singh, bioRxiv - Cell Biology 2023

  Quote: ... and anti-centrin-1 rabbit polyclonal (Abcam, #ab156858, 1:200 in IF).
• MCU-enriched dendritic mitochondria regulate plasticity in distinct hippocampal circuits

  Katy E. Pannoni, et al., bioRxiv - Neuroscience 2024

  Quote: ... Antibodies (MCU, 1:500 and Chicken anti-GFP, 1:500 Abcam ab13970) were diluted in blocking solution and sections were incubated for 72+ hours at room temperature (RT) ...
• Canine Mammary Tumours (CMTs) exploit Mitochondrial Cholesterol for aggressive reprogramming

  Liana Hardy, et al., bioRxiv - Cancer Biology 2024

  Quote: ... acNF-κB (1:500; ab19870) and β-Tubulin (1:1000, Abcam, ab6046). Membranes were washed in TBST (3 × 15 min at RT ...
• SOX21 suppresses GBM growth by repressing AP-1 regulated target genes

  Eltjona Rrapaj, et al., bioRxiv - Cancer Biology 2024

  Quote: ... KI67 (ThermoFischer, 14-5698-82; 1:200 or Abcam, ab16667; 1:250); FLAG (Abcam ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1:500 (Abcam, ab53290), rabbit anti-HER3 ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1:500 (Abcam, ab32121), rabbit anti-pHER3 ...