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1151 - 1200 of 10000+ citations for Flap endonuclease 1 FEN 1 Human since 2019

• A midbody component homolog, too much information/prc1-like, is required for microtubule reorganization during both cytokinesis and axis induction in the early zebrafish embryo

  S Nair, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1:1000 (Abcam ab15568). Confocal microscopy images were obtained using a Zeiss LSM 510 for fixed images or Zeiss LSM 780 (for high magnification including super-resolution microscopy ...
• Urgent Brain Vascular Regeneration Occurs via Lymphatic Transdifferentiation

  Jingying Chen, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Prox1 (1:1000, Abcam), and phospho-EphB4a (1:250 ...
• Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation

  Abdalla Akef, et al., bioRxiv - Cell Biology 2020

  Quote: ... IPO7 (Abcam, 1:1000), TP53 (Bethyl ...
• H3K9me1/2 methylation limits the lifespan of C. elegans

  Meng Huang, et al., bioRxiv - Genetics 2021

  Quote: ... H3K9me2 #1 (Abcam, ab1220), H3K9me2 #2 (Abcam ...
• NPRL3: Direct Effects on Human Phenotypic Variability, mTOR Signaling, Subcellular mTOR Localization, Cortical Lamination, and Seizure Susceptibility

  Philip H. Iffland II, et al., bioRxiv - Neuroscience 2020

  Quote: ... CTIP2 (1:500; Abcam), and MAP2 (1:100 ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... bexarotene (1 μM, Abcam) or αtRA (100 nM ...
• CD47 prevents the elimination of diseased fibroblasts in scleroderma

  Tristan Lerbs, et al., bioRxiv - Immunology 2020

  Quote: ... Collagen 1 (Abcam, #ab34710), FSP1 (MilliporeSigma ...
• Chromatin alterations in the aging lung change progenitor cell activity

  Samuel P. Rowbotham, et al., bioRxiv - Molecular Biology 2021

  Quote: ... PDPN (Abcam, 1:200) Ace2 ...
• Type I Interferon regulates cytokine-delayed neutrophil apoptosis, reactive oxygen species production and chemokine expression via activation of p38 MAPK

  Laurence Glennon-Alty, et al., bioRxiv - Immunology 2020

  Quote: ... Actin (1:10,000, Abcam). Secondary antibodies were anti-rabbit IgG (GE Healthcare ...
• GOLIATH regulates LDLR availability and plasma LDL cholesterol levels

  Bethan L. Clifford, et al., bioRxiv - Molecular Biology 2020

  Quote: ... LRP1 (1:1,000; Abcam), PDI (1:1,000 ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... bexarotene (1 μM, Abcam), or αtRA (100 nM ...
• LRRC8A regulates hypotonicity-induced NLRP3 inflammasome activation

  Jack P. Green, et al., bioRxiv - Immunology 2020

  Quote: ... caspase-1 (ab179515, abcam), gasdermin D (ab20945 ...
• Ex vivo infection of human skin with herpes simplex virus 1 reveals mechanical wounds as insufficient entry portals via the skin surface

  Nydia De La Cruz, et al., bioRxiv - Microbiology 2021

  Quote: ... polyclonal (Abcam, 1:20) were used as isotype controls.
• Investigation of Thyroid Hormone Associated Gene-Regulatory Networks during Hepatogenesis using an Induced Pluripotent Stem Cell based Model

  Audrey Ncube, et al., bioRxiv - Developmental Biology 2021

  Quote: ... HNF4α (1:250; Abcam), SOX17 (1:50 ...
• Glycocalyx-Mediated Vascular Dissemination of Circulating Tumor Cells

  Giovanni S. Offeddu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... VCAM-1 (AB134047, Abcam), ICAM-1 (MA5407 ...
• Direct therapeutic targeting of SWI/SNF induces epigenetic reprogramming and durable tumor regression in rhabdoid tumor

  Maggie H. Chasse, et al., bioRxiv - Cancer Biology 2019

  Quote: ... H3K27ac (Abcam, 1:1250), or human mitochondria (Abcam ...
• A secreted proteomic footprint for stem cell pluripotency

  Philip Lewis, et al., bioRxiv - Cell Biology 2021

  Quote: ... TRA-1-81 (Abcam) and transcription factors SOX2 ...
• HES1 is a Critical Mediator of the SHH-GLI3 Axis in Regulating Digit Number

  Deepika Sharma, et al., bioRxiv - Developmental Biology 2020

  Quote: ... LMNA (1:1000; Abcam), ACTIN (1:2000 ...
• SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes

  Lilian Gomes de Oliveira, et al., bioRxiv - Immunology 2021

  Quote: ... IBA1 (1:500, Abcam), and MAP2 (1:500 ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... p18 (Abcam 1:2000), PDX1 (Cell Signaling 1:1000) ...
• Access to PCNA by Srs2 and Elg1 controls the choice between alternative repair pathways in yeast

  Matan Arbel, et al., bioRxiv - Genetics 2020

  Quote: ... RPS6(1:1000,Abcam).
• Fibronectin-mediated inflammatory signaling through integrin α5 in vascular remodeling

  Madhusudhan Budatha, et al., bioRxiv - Physiology 2021

  Quote: ... CD68 (1:200, Abcam); CD45 (1:200 ...
• FBW7 couples structural integrity with functional output of primary cilia

  Eleni Petsouki, et al., bioRxiv - Cell Biology 2020

  Quote: ... CD106 (Abcam, 1:200) or goat ALP (Thermofisher ...
• Neutrophils in the brain are sources of neuroprotective molecules and demonstrate functional heterogeneity during chronic Toxoplasma gondii infection

  Kristina V. Bergersen, et al., bioRxiv - Immunology 2022

  Quote: ... gondii (1:300, Abcam); Chicken GAP43 (1:200 ...
• Pharmacological Modulation of Autophagy Prevents Mutant SOD1^G93A Induced Neurotoxicity in Experimental Models of Amyotrophic Lateral Sclerosis (ALS)

  Yue Bi, et al., bioRxiv - Neuroscience 2022

  Quote: ... SOD1 (1:200; Abcam), SQSTM1 (1:100 ...
• Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring

  McCoy Clementson, et al., bioRxiv - Neuroscience 2022

  Quote: ... (NeuN, 1:200, AbCam). Primary antibodies were diluted in 0.5% Triton X and incubated with brain tissue overnight at 4°C ...
• ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation

  Suyang Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... H2B (Abcam; 1:1,000), γ-H2AX (Biolegend ...
• ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation

  Suyang Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... H2A (Abcam; 1: 2,500), H2B (Abcam ...
• ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation

  Suyang Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... H4 (Abcam; 1:2,000), α-tubulin (Santa Cruz Biotechnology ...
• ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation

  Suyang Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... H2A (Abcam; 1:1,000), H2B (Abcam ...
• ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation

  Suyang Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... H2B (Abcam; 1: 2,500), H3 (Santa Cruz Biotechnology ...
• Direct conversion of human fibroblasts to pancreatic epithelial cells through transient progenitor states is controlled by temporal activation of defined factors

  Liangru Fei, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:1000 (Abcam, #ab150129); goat anti-mouse (Alexa Fluor 488) ...
• SNCA Deletion Induced Aberrant Projection of Olfactory Sensory Neurons via NCK2-EphA4 Pathway

  Jing Ren, et al., bioRxiv - Neuroscience 2022

  Quote: ... pEphA3(1:500, Abcam), pEphA4 (1:500 ...
• Ceramide synthase 6 (CerS6) promotes alcohol-induced fatty liver by promoting metabolic dysfunction and upregulating lipid droplet-associated proteins

  Sookyoung Jeon, et al., bioRxiv - Pathology 2022

  Quote: ... Plin3 (1:000, Abcam), and CerS6 (1,000 ...
• An Alzheimer’s disease patient-derived olfactory cell model identifies gene expression changes associated with cognition

  Laura M. Rantanen, et al., bioRxiv - Neuroscience 2022

  Quote: ... AQP4 (1:200, Abcam #9512 and S100b (1:200 ...
• Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring

  Lauren Hurley, et al., bioRxiv - Neuroscience 2023

  Quote: ... NeuN (1:200, AbCam). Primary antibodies were diluted in 0.5% Triton X and incubated on the brain tissue overnight at 4°C ...
• Delaying the GABA shift indirectly affects membrane properties in the developing hippocampus

  C. Peerboom, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 μM TTX (Abcam) was also added to the ACSF ...
• ARPC5 Isoforms and Their Regulation by Calcium-Calmodulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells

  Lopamudra Sadhu, et al., bioRxiv - Immunology 2022

  Quote: ... 1:1000 (#ab75829, Abcam), HRP-coupled secondary rabbit or mouse antibodies for immunoblotting were obtained from Jackson Immuno Research was used at a dilution of 1:5000 for all samples ...
• ARPC5 Isoforms and Their Regulation by Calcium-Calmodulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells

  Lopamudra Sadhu, et al., bioRxiv - Immunology 2022

  Quote: ... 1:1000 (EPR8533 Abcam), mouse anti-ARPC3 ...
• SNCA Deletion Induced Aberrant Projection of Olfactory Sensory Neurons via NCK2-EphA4 Pathway

  Jing Ren, et al., bioRxiv - Neuroscience 2022

  Quote: ... pEphA2(1:500, Abcam), pEphA3(1:500 ...
• SNCA Deletion Induced Aberrant Projection of Olfactory Sensory Neurons via NCK2-EphA4 Pathway

  Jing Ren, et al., bioRxiv - Neuroscience 2022

  Quote: ... pEphA1 (1:500, Abcam), pEphA2(1:500 ...
• An off-the-shelf multi-well scaffold-supported platform for tumour organoid-based tissues

  Nancy T Li, et al., bioRxiv - Bioengineering 2022

  Quote: ... 1 µM staurosporine (Abcam) was used as a 0% viability control ...
• 7q11.23 CNV alters protein synthesis and REST-mediated neuronal intrinsic excitability

  Marija Mihailovich, et al., bioRxiv - Neuroscience 2022

  Quote: ... KI67 (1:500 Abcam) and PAX6 (1:250 Abcam) ...
• 7q11.23 CNV alters protein synthesis and REST-mediated neuronal intrinsic excitability

  Marija Mihailovich, et al., bioRxiv - Neuroscience 2022

  Quote: ... CTIP2 (1:500 Abcam).
• ARHGEF18 participates in Endothelial Cell Mechano-sensitivity in Response to Flow

  Surya Prakash Rao Batta, et al., bioRxiv - Cell Biology 2022

  Quote: ... paxillin (Abcam, 1/1000),
• The transmembrane protein Syndecan regulates stem cell nuclear properties and cell maintenance

  Buffy L. Eldridge-Thomas, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1/1000 (Abcam, ab13970); rat anti-α-catenin ...
• OPA1 protects intervertebral disc and knee joint health in aged mice by maintaining the structure and metabolic functions of mitochondria

  Vedavathi Madhu, et al., bioRxiv - Cell Biology 2024

  Quote: ... (1:200; Abcam, ab3773). For mouse primary antibody Mouse on Mouse Kit (Vector laboratories ...
• Ribosome-binding protein 1, RRBP1, maintains peroxisomal biogenesis

  Kaneez Fatima, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:1000 (Abcam, 22595); anti-PMP70 ...
• Ribosome-binding protein 1, RRBP1, maintains peroxisomal biogenesis

  Kaneez Fatima, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:1000 (Abcam, 22595); anti-PMP70 ...
• Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity

  Liora S. Katz, et al., bioRxiv - Cell Biology 2024

  Quote: ... Pdx1 (Abcam, 1:500), and Insulin (Fisher ...