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751 - 800 of 10000+ citations for 3 1 3 Dioxan 2 yl 3' methoxypropiophenone since 2020

• Inactivation of the mitochondrial protease Afg3l2 results in severely diminished respiratory chain activity and widespread defects in mitochondrial gene expression

  Gautam Pareek, Leo J. Pallanck, bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Ref(2)p (1:500, abcam ab178440), mouse anti-ubiquitin (1:1000 ...
• Age and neuroinflammation are important components of the mechanism of cognitive and neurobehavioral deficits in sickle cell disease

  Raven A. Hardy, et al., bioRxiv - Neuroscience 2020

  Quote: ... panel 2 = anti-mouse BrdU (ab8152, Abcam, 1:500), anti-mouse Iba1 (019-19741 ...
• Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles

  Kathryn A. Jewett, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:200 rabbit anti-Ref(2)P (Abcam, ab178440), 1:500 mouse anti-ubiquitin (Santa Cruz ...
• Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in Drosophila neurons

  Ryan Insolera, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti Ref(2)p at 1:500 (Abcam #ab178440), anti Atg8 (GABARAP)* at 1:500 (Cell Signaling Technology #13733S) ...
• Targeting neuronal homeostasis to prevent seizures

  Fred Mulroe, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Pum 2 (1:1000, ab10361, Abcam, Cambridge, UK), anti-SCN1A (1:1000 ...
• AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells

  Takao Kitagawa, et al., bioRxiv - Cancer Biology 2022

  Quote: ... NKX2-2 (1:1000 dilution, Cat. No. ab187375, Abcam), p27 Kip1 (D69C12 ...
• The early endosomal protein Rab21 is critical for enterocyte functions and intestinal homeostasis

  Sonya Nassari, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-ref(2)p (ab178440, Abcam; 1/500), rabbit anti-dpERK (Thr202/Tyr204 ...
• Duox generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

  Amrutha Kizhedathu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Mouse Anti-8-Hydroxy-2’-deoxyguanosine (Abcam, 1:200), and Alexa 488/568-conjugated Donkey anti-Chicken/Rabbit/Mouse secondary antibodies (Invitrogen ...
• Age and neuroinflammation are important components of the mechanism of cognitive and neurobehavioral deficits in sickle cell disease

  Raven A. Hardy, et al., bioRxiv - Neuroscience 2020

  Quote: ... panel 2 = anti-mouse BrdU (ab8152, Abcam, 1:500), anti-mouse Iba1 (019-19741 ...
• 3D models of Alzheimer’s disease patient microglia recapitulate disease phenotype and show differential drug responses compared to 2D

  Carla Cuní-López, et al., bioRxiv - Neuroscience 2021

  Quote: ... Primary antibodies for TREM 2 (1:500; Abcam, # ab201621), P2RY12 (1:200 ...
• Distinct regulation of dopamine D3 receptor in the basolateral amygdala and dentate gyrus during the reinstatement of cocaine CPP induced by drug priming and social stress

  Rocío Guerrero-Bautista, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-glutaminase 2 (GLS2; 1:1000, ab113509, Abcam) and chicken anti-glutamate decarboxylase (GAD ...
• A novel glucocorticoid and androgen receptor modulator reduces viral entry and innate immune inflammatory responses in the Syrian Hamster model of SARS-CoV-2

  Savannah M. Rocha, et al., bioRxiv - Immunology 2021

  Quote: ... rabbit transmembrane serine protease 2 (TMPRSS2; Abcam; 1:500), mouse interleukin 6 (IL-6 ...
• A secreted proteomic footprint for stem cell pluripotency

  Philip Lewis, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:1000 rabbit anti-Neuronal Pentaxtrin 2 (Abcam, ab191563); 1/1000 rabbit anti-Neurotensin (Abcam ...
• GLT8D1 mutations cause amyotrophic lateral sclerosis via disruption of neurotrophin signalling within membrane lipid rafts

  Tobias Moll, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-caveolin-2 [1:500 dilution] (Abcam #ab3417). Protein bands were detected with horseradish peroxidase (HRP)-conjugated rabbit or mouse secondary antibody [1:1,000 dilution] (Promega) ...
• The inflammatory micro-environment induced by targeted CNS radiotherapy is underpinned by disruption of DNA methylation

  TO Millner, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-8-Hydroxy-2’-deoxyguanosine (1:100, Abcam), rabbit anti-NF-kB p65 (1:100 ...
• Non-canonical contribution of human Dicer helicase domain in antiviral innate immune response

  Morgane Baldaccini, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-SARS-CoV-2 Nucleocapsid (1:1000, ab273167 Abcam), anti-AGO2 (1:250 ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... type II collagen (COL 2, ab34712, 1:400, Abcam). All sections were incubated with a biotinylated secondary antibody and stained using the R&D HRP-DAB staining kit (R&D Systems ...
• Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling

  Tai Chaiamarit, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-Tyrosinated tubulin [YL1/2] (1:1000; Abcam). The concentration of Goat anti-KLC1 (V-17 ...
• Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53

  Jonathan D. Lee, et al., bioRxiv - Microbiology 2023

  Quote: ... SARS-CoV-2 spike glycoprotein (Abcam, ab272504, 1:500), or CXCL8 (CST ...
• Metabolic impact of trans 10, cis 12-conjugated linoleic acid on pai transgenic mice

  Yu Rao, et al., bioRxiv - Physiology 2023

  Quote: ... AMPK ⍺1 (phospho T183) + ⍺2 (phospho T172) (Abcam, AB133448), AMPK ⍺1 + ⍺2 (Abcam ...
• GelMap: Intrinsic calibration and deformation mapping for expansion microscopy

  Hugo G.J. Damstra, et al., bioRxiv - Cell Biology 2022

  Quote: ... rat anti-tubulin YL1/2 (1:200, Abcam ab6160), mouse anti-tau (1:500 ...
• An adult stem-like cell population generates germline and neurons in the sea anemone Nematostella vectensis

  Paula Miramón-Puértolas, Patrick R.H. Steinmetz, bioRxiv - Developmental Biology 2023

  Quote: ... rat anti-tubulin (YL1/2) 1:100 (Abcam Ab6160). After washes in 1xPBS/0.2% Triton X-100 ...
• Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells

  Marina Gattiglio, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and anti-total ERK1/2 1:1000 (Abcam, ab36991). Secondary antibodies used were IRDye-coupled donkey anti-mouse 800 at 1:500 and donkey anti-rabbit 680 ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... type II collagen (COL 2, ab34712, 1:1000, Abcam), Transferrin Receptor (TFR ...
• Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

  Laura Zein, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-TOMM40 [EPR6932(2)] (Abcam, ab185543, 1:1000), rabbit anti-NAK (phospho S172 ...
• Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain

  Marina Herwerth, et al., bioRxiv - Neuroscience 2024

  Quote: ... 6-diamidino-2-phenylindole (DAPI, 1:1000, ab228549, Abcam) for nuclear counterstaining.
• MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks

  Monica Torres Esteban, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-PELI1/2 (Rabbit monoclonal, 1:1000, Abcam, ab199336), anti-MDC1 (Rabbit polyclonal ...
• Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex

  Peristera Roboti, Craig Lawless, Stephen High, bioRxiv - Biochemistry 2021

  Quote: ... anti-Ubiquilin-2 (Abcam ab217056; 1:2000 for IB, 1:100 for IP), anti-V5 (Novus Biologicals NB600-379 ...
• Contribution of the neuron-specific ATP1A3 to embryonic spinal circuit emergence

  Sarah Dinvaut, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-Islet1/2 (39.4D5, DSHB, 1:500) anti-GFP (Ab5450, Abcam, 1:500), diluted in the blocking solution ...
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-LATS1/2 (T1079/T1041) (Cell Signaling, D57D3, Abcam, ab305029, 1:1,000 – 1:3,000), cJUN (Cell Signaling ...
• The V-ATPase/ATG16L1 axis is controlled by the V₁H subunit

  Lewis Timimi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse monoclonal anti-IAV matrix 2 (Abcam, ab5416, WB 1:1000, IF 1:100), mouse monoclonal anti-β-actin (Proteintech ...
• Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

  Alexander G. Sorets, et al., bioRxiv - Bioengineering 2024

  Quote: ... AQP4-488 (1:500 for overnight or 1:200 for 2 hours, Abcam ab284135), Glut1-PE (1:300 ...
• The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons

  Swati Mishra, et al., bioRxiv - Cell Biology 2022

  Quote: ... microtubule-associated protein 2 (MAP2) at 1:1000 (ab92434; Abcam); Ras-related protein Rab-7a (Rab7 ...
• Sensitisation of colonic nociceptors by TNFα is dependent on TNFR1 expression and p38 MAPK activity

  Katie H. Barker, et al., bioRxiv - Neuroscience 2022

  Quote: ... plus 4’-6-diamidino-2-phenylindole (DAPI; 1:1000, Abcam) for 1 hour at room temperature ...
• Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection

  Chang-ki Oh, et al., bioRxiv - Microbiology 2022

  Quote: ... or SARS-CoV-2 Spike protein (1:2000, Abcam, ab275759). After incubation with secondary antibodies (IR-dye 680LT-conjugated goat anti-mouse [1:20,000 ...
• Depletion of the AD risk gene SORL1 selectively impairs neuronal endosomal traffic independent of amyloidogenic APP processing

  Allison Knupp, et al., bioRxiv - Cell Biology 2020

  Quote: ... microtubule-associated protein 2 (Map2) at 1:1000 (Abcam ab92434); Nestin (NES ...
• Clr4^SUV39H1 and Bdf2^BRD4 ubiquitination mediate transcriptional silencing via heterochromatic phase transitions

  Hyun-Soo Kim, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1~2 μg of antibodies like anti-H3K9me2 (Abcam ab1220), anti-H3K9me3 (Absolute Antibody Ab00700-1.26) ...
• SARS-CoV-2 Omicron is specifically restricted in its replication in human lung tissue, compared to other variants of concern

  Or Alfi, et al., bioRxiv - Microbiology 2022

  Quote: ... α-SARS-CoV-2 Nucleocapsid (Rabbit monoclonal, 1:500, Abcam, ab271180). The following secondary antibodies were used ...
• The kinesin motor KIF1C is a putative transporter of the exon junction complex in neuronal cells

  Maike Nagel, et al., bioRxiv - Neuroscience 2022

  Quote: ... Anti-Mago nashi homolog 2 (ab186431 Abcam, rabbit 1:250), EIF4A3 (17504-1-AP Proteintech ...
• A dedicated hypothalamic oxytocin circuit controls aversive social learning

  Takuya Osakada, et al., bioRxiv - Neuroscience 2022

  Quote: ... and anti-GFP (1:2000, abcam, ab13970, lot#GR3190550-2). The secondary antibodies used were ...
• The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a Drosophila model of Parkinson’s disease

  Shuanglong Yi, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Ref(2)P (1:1000, Cat. #ab178440, Abcam), mouse anti-Mono- and poly-ubiquitinylated conjugates antibody (FK2 ...
• A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading

  Drice Challal, et al., bioRxiv - Genetics 2023

  Quote: ... 1 to 2 µL antibodies against total H3 (Abcam, ab1791), H3K9me2 (Abcam ...
• SERPINB3 induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer

  Yuuki Ohara, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 8-Hydroxy-2’-deoxyguanosine (8-OHdG) (Abcam, ab48508; 1:5000). Signals were amplified using the Dako EnVision+ System- HRP labelled polymer anti-mouse or rabbit antibody protocol ...
• Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids

  Xiao Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-TBR1 (rabbit, Abcam, ab31940, GR3215726-2, 1:100 dilution), anti-SATB2 (mouse ...
• Structural basis of epitope recognition by anti-alpha synuclein antibodies MJFR14-6-4-2

  Ilva Liekniņa, et al., bioRxiv - Neuroscience 2023

  Quote: ... or MJFR-14-6-4-2 (Abcam #209,538, 1:450,000). Protein was visualized with a secondary HRP conjugated antibody (Dako ...
• Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues

  Rayyan M. Gorashi, et al., bioRxiv - Bioengineering 2024

  Quote: ... runt-related transcription factor 2 (RUNX2, 1:300, Abcam, ab23981), Methyl-Lysine (MeK ...
• Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by reprogramming macrophages and increasing UCP1 expression in vascular smooth muscle cells

  Aneta Stachowicz, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... nitric oxide synthase 2 (iNOS) (dilution 1:200, Abcam UK) and arginase 1 (dilution 1:50 ...
• Cellular and molecular characterization of peripheral glia in the lung and other organs

  Shaina Hall, et al., bioRxiv - Cell Biology 2024

  Quote: ... 6-diamidino-2-phenylindole (DAPI) (1:10,000, ab228549; Abcam, USA) for 1hr ...
• Endocytosis restricts synapse growth by attenuating Highwire/PHR1-dependent JNK signaling in a pathway parallel to the BMP signaling

  Srikanth Pippadpally, et al., bioRxiv - Neuroscience 2024

  Quote: ... Rabbit anti-Ref(2)P (1:200; Abcam, Cambridge, UK), anti-Rab5 (1:500 (63 ...
• Gestational arsenite exposure alters maternal postpartum heart size and induces Ca²⁺ handling dysregulation in cardiomyocytes

  Nicole Taube, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... LTCC α-2 subunit (1:1000, Rabbit Ab, Abcam, ab253190), Mybp-c (1:1000 ...