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4851 - 4900 of 8552 citations for 5 Pyrimidinecarbonitrile 1 2R 2 3 dihydroxypropyl 1 2 3 4 tetrahydro 3 methyl 2 4 dioxo 9CI since 2019

• Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair

  Chen Hao Lo, et al., bioRxiv - Physiology 2020

  Quote: ... and viability staining (1:500; BioLegend; Cat. No. 423105). Samples were then stained by cell-surface conjugated antibodies from BioLegend diluted in autoMACS buffer (Miltenyi ...
• MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection

  Sharon Khuzwayo, et al., bioRxiv - Immunology 2020

  Quote: ... 1:25 of anti-CD3 PerCP/Cy5.5 (UCHT1, BioLegend), 1:25 of anti-CD4 BV785 (OKT4 ...
• A truncated form of HpARI stabilises IL-33, amplifying responses to the cytokine

  Caroline Chauché, et al., bioRxiv - Immunology 2020

  Quote: ... were coated with 1 μg mouse ST2-Fc (Biolegend), and washed on a DynaMag-2 magnet with PBS 0.02% Tween 20 ...
• Schizophrenia Risk Proteins ZNF804A and NT5C2 Interact at Synapses

  Afra Aabdien, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-Myc mouse monoclonal (BioLegend, 626802, 1:1000). Actin filaments were stained using ActinGreen™ 488 (Life Technologies ...
• Systematic analysis of CD39, CD103, CD137 and PD-1 as biomarkers for naturally occurring tumor antigen-specific TILs

  Monika A. Eiva, et al., bioRxiv - Immunology 2021

  Quote: ... and anti-PD-1-APCCy7 (BioLegend Cat# 329922, RRID:AB_10933429).
• SARS-CoV-2 genome-wide mapping of CD8 T cell recognition reveals strong immunodominance and substantial CD8 T cell activation in COVID-19 patients

  Sunil Kumar Saini, et al., bioRxiv - Immunology 2020

  Quote: ... and TNF-α (Biolegend, 502930; final dilution 1/20). Cells incubated with Leukocyte Activation Cocktail (BD Biosciences ...
• Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

  Tapash Jay Sarkar, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-CD34-FITC (clone 581; BioLegend; #343503, 1:75), anti-CD29-APC (clone TS2/16 ...
• Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

  Tapash Jay Sarkar, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-CD34-FITC (clone 581; BioLegend; #343503, 1:75), anti-CD29-APC (clone TS2/16 ...
• Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology

  Alexandra Sontheimer-Phelps, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-CD31-421 (clone, cat, BioLegend, dilution 1:20), EpCAM-PE/Cy7 (CO17-1A ...
• Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome

  Emily Lorenzen, et al., bioRxiv - Biochemistry 2019

  Quote: ... and 1:200 for PE-conjugated anti-HA (Biolegend). Following incubation at 4°C for one hour ...
• Cachexia and fibrosis are costs of chronic IL-1R-mediated disease tolerance in T. gondii infection

  Stephanie J. Melchor, et al., bioRxiv - Immunology 2019

  Quote: ... anti-PD-1-PE/Cy7 (BioLegend, clone 29F.1A12), anti-CD4-APC (BioLegend ...
• Role of the imprinted allele of the p57^Kip2 gene in mouse neocortical development

  Yui Imaizumi, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and APC-conjugated CD24 (mouse, 1:500, BioLegend, 101814)) ...
• A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia demonstrates cancer-crosstalk with stroma to impair normal tissue function

  Ninib Baryawno, et al., bioRxiv - Cell Biology 2019

  Quote: ... Gr-1-PE (Biolegend, Ref#108408, clone RB6-8C5), and Cd11b-PE (Biolegend ...
• Nanoscopic Clustering of Neuroligin-3 and Neuroligin-4X Regulates Growth Cone Organization and Size

  Nick J.F. Gatford, et al., bioRxiv - Neuroscience 2019

  Quote: Antibodies: mouse anti-HA monoclonal (BioLegend, 901503, 1:1000), rabbit anti-RFP polyclonal (MBL ...
• Protective mucosal immunity against SARS-CoV-2 after heterologous systemic RNA-mucosal adenoviral vector immunization

  Dennis Lapuente, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD69-PerCP-Cy5.5 (1:300, clone H1.2F3, BioLegend), anti-CD103-PE (1:200 ...
• IL-27 enhances the lymphocyte mediated innate resistance to primary hookworm infection in the lungs

  Jason B. Noon, et al., bioRxiv - Immunology 2020

  Quote: ... NK1.1-PerCP/Cy5.5 (clone: PK136; dilution: 1:100, BioLegend), IL-27RA-PE (clone ...
• Fast Transport of RNA Granules by Direct Interactions with KIF5A/KLC1 Motors Prevents Axon Degeneration

  Yusuke Fukuda, et al., bioRxiv - Cell Biology 2020

  Quote: ... and incubated with rabbit anti-Tuj1 (1:400; Biolegend) overnight at 4°C ...
• Palmitoylation targets the Calcineurin phosphatase to the Phosphatidylinositol 4-kinase complex at the plasma membrane

  Idil Ulengin-Talkish, et al., bioRxiv - Biochemistry 2021

  Quote: ... and anti-rabbit Brilliant Violet 421 (1:100, Biolegend). YFP (500 nm) ...
• Predictive profiling of SARS-CoV-2 variants by deep mutational learning

  Joseph M. Taft, et al., bioRxiv - Synthetic Biology 2021

  Quote: ... and 1 ng/μl anti-FLAG-PE (Biolegend 637310) for 30 minutes at 4 °C ...
• The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

  Kanagaraju Ponnusamy, et al., bioRxiv - Cancer Biology 2020

  Quote: ... The anti-IRF3 (1:500; BioLegend; clone number: 12A4A35), anti-TBK1 (1:1000 ...
• Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches

  Eliona Tsefou, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Beta III tubulin (Biolegend, 801201, 1 in 2000), anti-GFAP (CST ...
• Odor Blocking Of Stress

  Eun Jeong Lee, et al., bioRxiv - Neuroscience 2021

  Quote: ... and biotinylated anti-HA antibodies (BioLegend, #901505, 1:300) at 37°C for 2 h ...
• Notch Signaling Commits Mesoderm to the Cardiac Lineage

  Evan S. Bardot, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-human CD184 (CXCR4) (Biolegend, clone 12G5; 1:500).
• Immunoresolvents Support Skeletal Myofiber Regeneration via Actions on Myeloid and Muscle Stem Cells

  James F. Markworth, et al., bioRxiv - Immunology 2020

  Quote: ... CD29/β1-integrin-PE (Biolegend [Clone HMb-1; 102208]), and CD184/CXCR-4-BIOTIN (BD Biosciences [Lot 6336587 ...
• Single-cell transcriptome analysis of the immunosuppressive effect of differential expression of tumor PD-L1 on responding TCR-T cells

  Renpeng Ding, et al., bioRxiv - Immunology 2020

  Quote: ... PE-anti-human CD279(PD-1) antibody (Biolegend, 367404), PE anti-mouse TCR β chain Antibody (Biolegend ...
• Activation of Sarm1 produces cADPR to increase intra-axonal calcium and promote axon degeneration in CIPN

  Yihang Li, et al., bioRxiv - Neuroscience 2021

  Quote: ... and incubated with mouse anti-Tuj1 (1:500; BioLegend) overnight at 4°C ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... PD1-APC (clone RMP1-30, Biolegend 109112, 1:200), PD-L1-PE (clone MIH5 ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... CD8-FITC (clone 53-6.7, Biolegend 100706, 1:200), CD69-APC/Cy7 (clone H1.2F3 ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... CD69-APC/Cy7 (clone H1.2F3, Biolegend 104526, 1:200), PD1-APC (clone RMP1-30 ...
• ASC oligomer favor caspase-1^CARD domain recruitment after intracellular potassium efflux

  Fátima Martín-Sánchez, et al., bioRxiv - Immunology 2020

  Quote: ... mouse monoclonal anti-ASC (TMS-1) was from Biolegend; rabbit polyclonal anti-tubulin and anti-Luciferase from Abcam ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... CD62L-Alexa700 (clone MEL-14, Biolegend 104426, 1:400), CX3CR1-BV605 (clone SA011F11 ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... CD45-PacificBlue (clone 30-F11, Biolegend 103126, 1:400), CD45.1 PerCp (Biolegend 110726 ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... CD11c-PE/Cy7 (clone N418, Biolegend 117318, 1:400), MHC-II-Alexa700 (clone M5/114.15.2 ...
• Lymphatic PD-L1 expression restricts tumor-specific CD8⁺ T cell responses

  Nikola Cousin, et al., bioRxiv - Immunology 2021

  Quote: ... CD31-PerCp/Cy5.5 (clone MEC13.3, Biolegend 102522, 1:300), podoplanin-PE ...
• Contribution of resident and circulating precursors to tumor-infiltrating CD8⁺ T cell populations in non-small cell lung cancer patients

  Paul Gueguen, et al., bioRxiv - Immunology 2020

  Quote: ... KLRG1-PE-Cy7 (1:40, clone SA231A2, #B256810, Biolegend), TIM3-BV786 (1:40 ...
• IL-27 enhances the lymphocyte mediated innate resistance to primary hookworm infection in the lungs

  Jason B. Noon, et al., bioRxiv - Immunology 2020

  Quote: ... CD19-PE/Cy7 (clone: 6D5; dilution: 1:100, BioLegend), NK1.1-PerCP/Cy5.5 (clone ...
• IL-27 enhances the lymphocyte mediated innate resistance to primary hookworm infection in the lungs

  Jason B. Noon, et al., bioRxiv - Immunology 2020

  Quote: ... NK1.1-PerCP/Cy5.5 (clone: PK136; dilution: 1:100, BioLegend), IL-27RA-PE (clone ...
• Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch

  Chris H. Hill, et al., bioRxiv - Molecular Biology 2021

  Quote: ... mouse monoclonal anti-RPS6 (1/1000, clone A16009C, BioLegend); mouse monoclonal anti-RPL4 (1/1000 ...
• Fine-tuning of β-catenin in thymic epithelial cells is required for postnatal T cell development

  Sayumi Fujimori, et al., bioRxiv - Immunology 2021

  Quote: ... and mouse anti-Keratin 8 antibody (BioLegend, 1:500) was performed after heat-induced antigen retrieval ...
• CXCL10⁺ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter

  Hen Prizant, et al., bioRxiv - Immunology 2020

  Quote: ... anti-CD26 PE-Cy7 (1:50, H194-112, Biolegend), anti-XCR1 BV650 (1:200 ...
• CXCL10⁺ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter

  Hen Prizant, et al., bioRxiv - Immunology 2020

  Quote: ... anti-CD88 anti-APC (1:800, 20/70, Biolegend), anti-MHC-II APC-ef780 (1:2000 ...
• Molecular tracking devices quantify antigen distribution and archiving in the lymph node

  Shannon M. Walsh, et al., bioRxiv - Immunology 2020

  Quote: ... CD8 APC-Cy7 (Biolegend clone 53-6.7 1:400) for 1hr at 37C ...
• Pro-autoimmune allele of tyrosine phosphatase, PTPN22, enhances tumor immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2021

  Quote: ... CD45 (BV570/BV605, Biolegend, 1:200, clone 30-F11), CD3e (PE-Cy5/AF532 ...
• Pro-autoimmune allele of tyrosine phosphatase, PTPN22, enhances tumor immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2021

  Quote: ... CD11b (PerCP-Cy5.5, Biolegend, 1:200, clone M1/70), F4/80 (Pacific Orange ...
• Expansion of CD10^neg neutrophils and CD14⁺HLA-DR^neg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction

  Daniela Fraccarollo, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD182 (clone SA044G4/clone SA045E1, 1:100 BioLegend); anti-CD101 (clone Moushi101 ...
• Human immunodeficiency reveals GIMAP5 as lymphocyte-specific regulator of senescence

  Ann Y. Park, et al., bioRxiv - Immunology 2021

  Quote: ... and 1 μg/mL anti-CD28 (clone CD28.2, BioLegend). After 3 days ...
• Generation of cell-free matrices that support human NK cell migration and differentiation

  Barclay J. Lee, Emily M. Mace, bioRxiv - Cell Biology 2020

  Quote: ... CD3 (Clone SK7, Brilliant Violet 711, BioLegend, 1:100), CD16 (Clone 3G8 ...
• Capturing limbal epithelial stem cell population dynamics, signature, and their niche

  Anna Altshuler, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cd3e (BioLegend 100311, IF-Wmt 1:100 APC conujugated), Cd8 (BioLegend 100706 ...
• Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) is Required for Immune Priming of the Endothelium in Atherogenic Disturbed Flow Conditions

  Jessica A Hensel, et al., bioRxiv - Cell Biology 2021

  Quote: ... and Cd11b (1:200, Biolegend, 10112, clone M1/70). LSR Aria-IIA (BD Biosciences ...
• Distinct SARS-CoV-2 sensing pathways in pDCs driving TLR7-antiviral vs. TLR2-immunopathological responses in COVID-19

  Renée M. van der Sluis, et al., bioRxiv - Immunology 2021

  Quote: ... CD56 (anti-human Lineage cocktail 1 – FITC, BioLegend 348801). From total DCs ...