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4451 - 4500 of 8552 citations for 5 Pyrimidinecarbonitrile 1 2R 2 3 dihydroxypropyl 1 2 3 4 tetrahydro 3 methyl 2 4 dioxo 9CI since 2019

• In vivo single-cell CRISPR uncovers distinct TNF-α programs in clonal expansion and tumorigenesis

  Peter F. Renz, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rat anti-CD45-biotin (Biolegend, 103104; 1:200), goat anti-TNFR1 (R&D ...
• An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic Microenvironment of Pancreatic Cancer

  Ileana L. Co, et al., bioRxiv - Bioengineering 2023

  Quote: ... human anti-CD8 (1:400; BioLegend, clone: SK1), human anti-TNFα (1:400 ...
• An Engineered 3D Co-culture Model of Primary Macrophages and Patient-Derived Tumour Cells to Explore Cellular Responses in the Graded Hypoxic Microenvironment of Pancreatic Cancer

  Ileana L. Co, et al., bioRxiv - Bioengineering 2023

  Quote: ... human anti-GZMB (1:400; BioLegend, clone: QA18A28), human anti-Ki67 (1:200 ...
• PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

  Catherine M. Kerr, et al., bioRxiv - Microbiology 2023

  Quote: ... CD69 (PE, Biolegend, 1:200, clone H1-2F3), CD103 (PerCP-ef710 ...
• Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination

  Yuhao Li, et al., bioRxiv - Microbiology 2023

  Quote: ... anti-TNF-α (BioLegend, MP6-XT22, 1:200), and anti-GrB (Invitrogen ...
• The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation

  Yuzhong Cheng, Fountane Chan, Judith A. Kassis, bioRxiv - Developmental Biology 2023

  Quote: ... anti-HA.11 (1:1000, clone 16B12, Biolegend), rabbit anti-Gal4 activation domain (1:1000 ...
• CD38 regulates ovarian function and fecundity via NAD⁺ metabolism

  Rosalba Perrone, et al., bioRxiv - Developmental Biology 2023

  Quote: ... CD127-PE (BioLegend, clone S18006K, 158204, 1:400), CD11c-PE-Fire_810 (BioLegend ...
• CD38 regulates ovarian function and fecundity via NAD⁺ metabolism

  Rosalba Perrone, et al., bioRxiv - Developmental Biology 2023

  Quote: ... TCRgd-APC (BioLegend, clone GL3, 118115, 1:400); IgD-Alexa_Fluor_647 (BioLegend ...
• In vivo screening of tumor-hepatocyte interactions identifies Plexin B2 as a gatekeeper of liver metastasis

  Costanza Borrelli, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Plexin B2-PE (1:500, Biolegend #145903), anti-GFP-AlexaFluor488 (1:200 ...
• WFIKKN2 is a bifunctional axon guidance cue that signals through divergent DCC family receptors

  Kelsey R. Nickerson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit polyclonal antibodies against TuJ1 (Biolegend, 1:500), Peripherin (Millipore ...
• Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

  Irina Veith, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-OX-40 (Biolegend, #350012, diluted 1:20), anti-CD137 (BD ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... CD8α (1:200 dilution; clone 53-6.7, BioLegend), CD4 (1:200 dilution ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Ly6G (1:400; APC-Cy7; BioLegend #127624), anti-CD19 (1:100 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD169 (1:200; PE-Cy7; BioLegend #142412), anti-PDCA-1 (1:200 ...
• ISWI1 complex proteins facilitate developmental genome editing in Paramecium

  Aditi Singh, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and mouse anti-His (1:2500, 362601, BioLegend) were diluted in 5% BSA in 1× PBS + 0.2% Tween20 for blotting ...
• Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells

  Eva Morgun, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse CD279/PD-1 (29F.1A12, Biolegend), and anti-Ki67 (SolA15 ...
• Androgen exposure impairs neutrophil maturation and function within the infected kidney

  Teri N. Hreha, et al., bioRxiv - Immunology 2023

  Quote: ... Rat anti-Ly6G-APC (1:200, Biolegend #127614), Rat anti-CD101-PE (1:150 ...
• Activated interstitial macrophages are a predominant target of viral takeover and focus of inflammation in COVID-19 initiation in human lung

  Timothy Ting-Hsuan Wu, et al., bioRxiv - Genomics 2023

  Quote: ... CD169/Siglec-1 (Clone 7-239, Biolegend 346002), or CD209/DC-SIGN (Clone 120507 ...
• Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance

  Harriet J. Watt, et al., bioRxiv - Immunology 2023

  Quote: ... followed by anti-rabbit Dylight649 (1:500) (Biolegend), NTAL-PE (1:100 ...
• CD4⁺ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

  Viviana Rubino, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Ter119 (clone Ter-119) (all 1:300; BioLegend), followed by staining with V500-streptavidin (1:1000 ...
• Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a-Mutant Hematopoietic Stem Cells

  Logan S. Schwartz, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Gr-1 (BioLegend, Invitrogen clone RB6-8C5)) ...
• Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response

  Lachlan P. Deimel, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse CD3-PE (1:200, 17A2, Biolegend), anti-mouse CD4-PE (1:200 ...
• An Interleukin 9-Zbtb18 axis promotes germinal center development of memory B cells

  Xiaocui Luo, et al., bioRxiv - Immunology 2023

  Quote: ... APC anti-IgM (RMM-1) (all from Biolegend); NP-PE and NIP-biotin (both from Biosearch Technologies) ...
• MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size

  Michael J. Lafferty, et al., bioRxiv - Genetics 2023

  Quote: ... and 1:1000 mouse-anti-TUJ1 (BioLegend 801202). After overnight incubation ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... BV786 anti-mouse CD11b (101243, BioLegend, 1:100); PE-Texas Red anti-mouse CD11c (117348 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... PeCy7 anti-mouse CD4 (100422, BioLegend, 1:100); BV750 anti-mouse CD3 (100249 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... PeCy7 anti-mouse CD4 (100422, BioLegend, 1:100); APC anti-mouse/human CD45R/B220 (103212 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... BV750 anti-mouse CD3 (100249, BioLegend, 1:100); BUV395 anti-mouse CD69 (740220 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... BV711 anti-mouse CD8a (100748, BioLegend, 1:100); BV786 anti-mouse CD11b (101243 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... BUV661 anti-mouse CD45 (103147, BioLegend, 1:100); BV570 anti-mouse Ly-6C (128030 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... BV650 anti-mouse CD3 (100229, BioLegend, 1:100); BV711 anti-mouse CD8a (100748 ...
• Systemic effects of melanoma-secreted MIDKINE in the inhibition of dendritic cell differentiation and function

  Xavier Catena, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and MHCII (1:300; M5/114.15.2; Biolegend; 107601)) ...
• Detection of tumor-derived extracellular vesicles interactions with immune cells is dependent on EV-labelling methods

  Luisa Loconte, et al., bioRxiv - Cell Biology 2023

  Quote: ... Pecy-7 (Biolegend, clone HCD14, diluted 1/100); anti-CD16 ...
• Detection of tumor-derived extracellular vesicles interactions with immune cells is dependent on EV-labelling methods

  Luisa Loconte, et al., bioRxiv - Cell Biology 2023

  Quote: ... Pecy5-A (Biolegend, clone OKT4,, diluted 1/100) ...
• Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies

  Katrin Fischer, et al., bioRxiv - Immunology 2023

  Quote: ... or helix green (1 nM final concentration, BioLegend) were added to each tube ...
• Flexible and scalable control of T cell memory by a reversible epigenetic switch

  Kathleen Abadie, et al., bioRxiv - Immunology 2023

  Quote: ... 1:200 (anti-CD45.2: PE/Dazzle594, Biolegend, #109846) or 1:100 (anti-CD127/IL7Rɑ ...
• Synthetic STING agonists elicit powerful vaccine adjuvancy providing robust central memory and anti-tumour effects

  Laurence D. Towner, et al., bioRxiv - Immunology 2023

  Quote: ... PD-1-PECy7 (RMP1-30)(preceding from Biolegend), (iv ...
• The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

  Claudia Carlantoni, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rat anti-CD31 (Cat#: 102501, BioLegend, 1:100), mouse anti-PDE2A (Cat# ...
• Subcellular second messenger networks drive distinct repellent-induced axon behaviors

  S Baudet, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and βIII-tubulin (1//1000, Biolegend, lot #B249869) followed by a secondary antibody coupled to AlexaFluor 488 (1/500 ...
• A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped mice

  Matthew R. Johnson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... or rabbit anti-Krt14 (BioLegend #905301, 1:1000) were diluted in 1x PBT/3%BSA and slides were incubated at 4°C O/N ...
• Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs

  Ola Bagato, et al., bioRxiv - Immunology 2023

  Quote: ... rat anti-Ki-67 (Biolegend, #652401, 1:200), rabbit anti-vWF (Dako ...
• Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements

  Yan Hu, et al., bioRxiv - Genomics 2023

  Quote: ... B220 clone RA3-6B2 (Biolegend, 103204; 1:200), GR1 (Ly6-G/Ly6-C ...
• Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements

  Yan Hu, et al., bioRxiv - Genomics 2023

  Quote: ... CD8 clone 53-6.7 (Biolegend, 100704; 1:400), CD19 clone 6D5 (Biolgend ...
• Loss of Rab8a in B cells leads to increased antibody responses and class-switch recombination

  Sara Hernández-Pérez, et al., bioRxiv - Immunology 2023

  Quote: ... and PE anti-CD3 (1:200; Biolegend, #100308). Samples were washed one more time and acquired on BD LSR Fortessa ...
• The molecular mechanism for carbon catabolite repression of the chitin response in Vibrio cholerae

  Virginia E. Green, et al., bioRxiv - Microbiology 2023

  Quote: ... or mouse monoclonal α-RpoA (1:1000, Biolegend). Membranes were then washed and incubated for at least 2 hours with either α-rabbit or α-mouse horseradish peroxidase-conjugated secondary antibodies (1:10,000) ...
• Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

  Hazel Stewart, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-CD63 (BioLegend, H5C6, IF 1:300), mouse anti-EEA1 (BD Transduction ...
• Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s Disease

  Despoina Charou, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... p75NTR (1:1000, 839701, Biolegend, San Diego, USA), Traf6 (1:2000 ...
• TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA

  Jelle Verhoeven, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and MHCII (1:100 dilution, FITC; Biolegend #107605). eBioscience™ Fixable Viability Dye eFluor™ 780 (1:1000 dilution,Thermo # 65-0865-14 ...
• SeMOE allows for quantitative glycan perception and exhibits anti-cancer potentiality

  Xiao Tian, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-mouse CD80-PE (Biolegend, 104707, 1:200) and anti-mouse CD206-APC (Biolegend ...
• Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection

  Geoffrey T. Norris, et al., bioRxiv - Immunology 2023

  Quote: ... rat anti-CD68 (1:300; FA-11; Biolegend), Goat anti-IL-33 (AF3626 ...