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3751 - 3800 of 8552 citations for 5 Pyrimidinecarbonitrile 1 2R 2 3 dihydroxypropyl 1 2 3 4 tetrahydro 3 methyl 2 4 dioxo 9CI since 2019

• Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

  Chima V. Maduka, et al., bioRxiv - Bioengineering 2023

  Quote: ... BV785 F4/80 (1:300, Biolegend, 123141), BV421 CD86 (1:200 ...
• CAR T cells recognizing CD276 and Dual-CAR T cells against CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models

  Andrea Timpanaro, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PE-CD95 (FAS) (1:100; BioLegend, #305608); PE-Cy7-CD45RA (1:100 ...
• A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa

  Gernot Neumayer, et al., bioRxiv - Bioengineering 2023

  Quote: ... K14 (1:800, BioLegend SIG-3476-100), and p63 (1:100 Gene Tex GTX102425) ...
• Chronic demyelination of rabbit lesions is attributable to failed oligodendrocyte progenitor cell repopulation

  James J. M. Cooper, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat IgG Smi311 & Smi312 (1:1000, BioLegend), rabbit IgG anti-App (1:500 ...
• Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

  Alice Santi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and human TruStain FcXTM (1/200, BioLegend) in 100 μl of FACS buffer for 45min on ice ...
• Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

  Alice Santi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and mouse TruStain FcXTM (1/200, BioLegend) for 45min on ice ...
• Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

  Alice Santi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and human TruStain FcXTM (1/200, BioLegend) in 100 μl of FACS buffer for 45min on ice ...
• Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

  Goran Tomić, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and Nkp46 antibody (1:40, PE, Biolegend) for 30 min on ice ...
• A dual MTOR/NAD+ acting gerotherapy

  Jinmei Li, et al., bioRxiv - Genomics 2023

  Quote: ... mouse SMI-32 (BioLegend 801701; 1:1000). The respective secondary antibodies (Molecular Probes ...
• ATG5 suppresses type I IFN-dependent neutrophil swarming and NETosis

  Rachel L. Kinsella, et al., bioRxiv - Immunology 2023

  Quote: ... and AF647-Ly6G (BioLegend, 1A8, 1:200) antibodies and 5 μg/mL Hoechst 33342 (Molecular Probes ...
• Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

  Alastair Copland, et al., bioRxiv - Immunology 2023

  Quote: ... PD-1-PE/Cy7 (29F.1A12; Biolegend), CD90.2-APC (53-2.1 ...
• Tregs constrain CD8⁺ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy

  Joseph R. Palmeri, et al., bioRxiv - Immunology 2023

  Quote: ... αPD-1-PerCp/Cy5.5 (29F.1A12, Biolegend), αFoxp3-PE (FJK-16s ...
• Increased TCR signaling in regulatory T cells is disengaged from TCR affinity

  Yi Jing, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD8b-biotin (BioLegend, YTS156.7.7, 1:8000) primary antibodies followed by secondary labelling with PE SA(BioLegend ...
• Flexible and scalable control of T cell memory by a reversible epigenetic switch

  Kathleen Abadie, et al., bioRxiv - Immunology 2023

  Quote: ... 1:400 (anti-CD45.1: APC, Biolegend, #110714), 1:200 (anti-CD45.2 ...
• A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity

  Kristina R. Rivera, et al., bioRxiv - Cell Biology 2023

  Quote: ... APC Annexin V (1:200, 640941; BioLegend) was added to cells for live/dead discrimination ...
• The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis

  Bianca M. Lupan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and Tuj1 (TUBB3, Biolegend, 801202, 1:2000).
• An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma

  Madelon M.E. de Jong, et al., bioRxiv - Immunology 2023

  Quote: ... and CD16-BV510 (1:300; 3G8, BioLegend). DAPI (Life Technologies ...
• IGF2BP1/IMP1 deletion enhances a facultative stem cell state via regulation of MAP1LC3B

  Louis R. Parham, et al., bioRxiv - Cell Biology 2023

  Quote: ... CD24-APC (1:500, BioLegend Cat# 101813); UEA-1 (1:500 ...
• Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs

  Ola Bagato, et al., bioRxiv - Immunology 2023

  Quote: ... rat anti-CD68 (BioLegend, #137001, 1:400), rat anti-Ki-67 (Biolegend ...
• Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements

  Yan Hu, et al., bioRxiv - Genomics 2023

  Quote: ... CD4 clone GK15 (Biolegend, 1000404; 1:400), CD5 clone 53-7.3 (eBioscience ...
• Loss of Rab8a in B cells leads to increased antibody responses and class-switch recombination

  Sara Hernández-Pérez, et al., bioRxiv - Immunology 2023

  Quote: ... APC anti-CD19 (1:200; BioLegend, #392503) and PE anti-CD3 (1:200 ...
• Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes generation of the whole lung

  Akihiro Miura, et al., bioRxiv - Developmental Biology 2023

  Quote: ... or Epcam-BV421 (Biolegend, 118225, 1/50), Aqua Zombie (BioLegend ...
• Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis

  Charlotte R. Wayne, et al., bioRxiv - Neuroscience 2023

  Quote: ... and CD11b (BV421, BioLegend, 101235, 1:100) for 30 minutes on ice ...
• A Human Breast Cell Atlas Mapping the Homeostatic Cellular Shifts in the Adult Breast

  Austin D. Reed, et al., bioRxiv - Cancer Biology 2023

  Quote: ... EPCAM-AF488 (Biolegend, clone 9C4, 1:50), CD49f-PE/Cy7 (Biolegend ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD45-PE (cat# 103106, Biolegend, 1:200), CD11b-APC (cat# 101212 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and ALIX (cat# 634502, Biolegend 1:2000) were used to validate TEV protein markers ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD45-PE (cat#103106, Biolegend, 1:200). um
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD4-BV510 (cat# 100449, Biolegend, 1:100) CD11b-FITC (cat# 101206 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD19-FITC (cat# 115506, Biolegend, 1:100) Nk1.1-FITC (cat# 108706 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD11b-APC (cat# 101212, Biolegend, 1:100), IA/12E-APC-Cy7 (cat# 107628 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Nk1.1-FITC (cat# 108706, Biolegend, 1:100) CD45-PE (cat# 103106 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Nk1.1-FITC (cat# 108706, Biolegend, 1:100) CD45-PE (cat#103106 ...
• Allogeneic Tumor Cell-Derived Extracellular Vesicles Stimulate CD8 T Cell Response in Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD11b-FITC (cat# 101206, Biolegend, 1:100) CD19-FITC (cat# 115506 ...
• EGFR⁺ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

  Alexandra Kuhlmann-Hogan, et al., bioRxiv - Immunology 2023

  Quote: ... αMHCII (1:300; BioLegend Cat# 107624, RRID:AB_2191073), αABCG1 (1:200 ...
• EGFR⁺ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

  Alexandra Kuhlmann-Hogan, et al., bioRxiv - Immunology 2023

  Quote: ... αLy6G (1:300; BioLegend Cat# 127624, RRID:AB_10640819), αCD11c(1:300 ...
• EGFR⁺ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

  Alexandra Kuhlmann-Hogan, et al., bioRxiv - Immunology 2023

  Quote: ... αCD4 (1:300; BioLegend Cat# 100406, RRID:AB_312691), αCD8a (1:300 ...
• EGFR⁺ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

  Alexandra Kuhlmann-Hogan, et al., bioRxiv - Immunology 2023

  Quote: ... αCD200R (1:300; BioLegend Cat# 123908, RRID:AB_2074080), αPD-L1 (1:300 ...
• EGFR⁺ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

  Alexandra Kuhlmann-Hogan, et al., bioRxiv - Immunology 2023

  Quote: ... αTNFα (1:300; (BioLegend Cat# 506305, RRID:AB_315426), αCD200R (1:300 ...
• EGFR⁺ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

  Alexandra Kuhlmann-Hogan, et al., bioRxiv - Immunology 2023

  Quote: ... αEPCAM (1:300; BioLegend Cat# 118212, RRID:AB_1134101), αCD31 (1:300 ...
• TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA

  Jelle Verhoeven, et al., bioRxiv - Cancer Biology 2023

  Quote: ... VCAM1 (1:200 dilution, FITC; Biolegend #105705), ICAM1 (1:200 dilution ...
• TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA

  Jelle Verhoeven, et al., bioRxiv - Cancer Biology 2023

  Quote: ... MHCI (1:100 dilution, APC; Biolegend #107613) and MHCII (1:100 dilution ...
• Longitudinal analysis of memory T follicular helper cells and antibody response following CoronaVac vaccination

  Pengcheng Zhou, et al., bioRxiv - Immunology 2023

  Quote: ... and anti-CD49d (1 ug/mL, Biolegend) were added ...
• Longitudinal analysis of memory T follicular helper cells and antibody response following CoronaVac vaccination

  Pengcheng Zhou, et al., bioRxiv - Immunology 2023

  Quote: ... and anti-CD49d (1 ug/mL, Biolegend) were added ...
• IL-36/IL-36R Signaling Promotes CD4+ T Cell-Dependent Colitis via Pro-Inflammatory Cytokine Production

  Maya Maarouf, Michal Kuczma, Timothy L. Denning, bioRxiv - Immunology 2023

  Quote: ... and 1:1000 monensin (both from BioLegend). Cells were stimulated for 4 hours in the TC incubator ...
• Disrupting microglial TGF-β signaling triggers region-specific pathology in the spinal cord

  Keying Zhu, et al., bioRxiv - Neuroscience 2023

  Quote: ... PE anti-Ly6C (1:250, 128008, BioLegend), APC anti-F4/80 (1:100 ...
• Disrupting microglial TGF-β signaling triggers region-specific pathology in the spinal cord

  Keying Zhu, et al., bioRxiv - Neuroscience 2023

  Quote: ... PE anti-Ly6C (1:250, 128008, BioLegend), and APC anti-F4/80 (1:100 ...
• TREM2 mediates MHCII-associated CD4⁺ T cell response against gliomas

  Jiaying Zheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... PerCP anti-CD45 (1:100, BioLegend, 103130), PE-Cy5 anti-CD11b (1:1000 ...
• Influence of Alzheimer’s disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex

  Sang Ho Kwon, et al., bioRxiv - Neuroscience 2023

  Quote: ... clone 6E10 (Biolegend, Cat# 803001, 1:50) overnight at 4°C ...
• TREM2 mediates MHCII-associated CD4⁺ T cell response against gliomas

  Jiaying Zheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... BV650 anti-Ly6C (1:100, BioLegend, 128049), BV750 anti-MHCII (1:500 ...
• TREM2 mediates MHCII-associated CD4⁺ T cell response against gliomas

  Jiaying Zheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... BV421 anti-CD62L (1:100, BioLegend, 115537), BV510 anti-CD4 (1:50 ...