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3701 - 3750 of 8552 citations for 5 Pyrimidinecarbonitrile 1 2R 2 3 dihydroxypropyl 1 2 3 4 tetrahydro 3 methyl 2 4 dioxo 9CI since 2019

• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... CD86 (BV605, Biolegend, 1:200, clone GL1), PD-1 (PE-Cy7 ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... NK1.1 (FITC, Biolegend, 1:100, clone PK136), CD19 (BV711 ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... IFNγ (AF647, Biolegend, 1:100, clone XMG1.2), TNFα (PE-Cy7 ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... CD44 (AF700, Biolegend, 1:200, clone IM7), CD62L (FITC ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... CXCR5 (BV605, Biolegend, 1:100, clone L138D7), Tbet (APC/AF647 ...
• Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

  Allen L. Pan, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Aβ (1:1,000, 6E10, Biolegend, 803001); anti-GFAP (1:1000 ...
• Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers

  Isaac Dean, et al., bioRxiv - Immunology 2023

  Quote: ... PD-1 PE-Cy7 (RMP1-30, BioLegend), Perforin APC (S16009A ...
• Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

  Janos Groh, et al., bioRxiv - Neuroscience 2023

  Quote: ... SMI32 (1:1,000, catalog no. 801701; BioLegend); rat anti-CD8 (1:500 ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... K10 (BioLegend; catalog no. 905404; 1:200); Donkey anti-Rabbit IgG Alexa Fluor 555 (Invitrogen ...
• Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

  Chima V. Maduka, et al., bioRxiv - Bioengineering 2023

  Quote: ... and AF700 CD11b (1:400, Biolegend, 101222). Cells and antibody mixture were incubated for 30 minutes ...
• Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

  Chima V. Maduka, et al., bioRxiv - Bioengineering 2023

  Quote: ... SparkBlue 550 CD3 (1:100, Biolegend, 100259), APC-Fire 810 CD4 (1:100 ...
• Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

  Chima V. Maduka, et al., bioRxiv - Bioengineering 2023

  Quote: ... AF647 IL-17a (1:200, Biolegend, 506911) and PE-Cy7 Arg1 (1:100 ...
• Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

  Chima V. Maduka, et al., bioRxiv - Bioengineering 2023

  Quote: ... APC-Fire750 IFNγ (1:80, Biolegend, 505859), AF647 IL-17a (1:200 ...
• Autoimmune inflammation triggers aberrant astrocytic calcium signaling to impair synaptic plasticity

  AM Baraibar, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-MBP (1:1000, Biolegend, 808402), mouse anti-Olig2 (1:500 ...
• A collaboration between immune cells and the choroid plexus epithelium in brain inflammation

  Huixin Xu, et al., bioRxiv - Neuroscience 2023

  Quote: ... clone 429 (MVCAM.A) (BioLegend 105728, 1:50), rat Ultra-LEAF™ purified anti-mouse CD54 antibody ...
• A collaboration between immune cells and the choroid plexus epithelium in brain inflammation

  Huixin Xu, et al., bioRxiv - Neuroscience 2023

  Quote: ... + F4/80-PE 1:100 (BioLegend, #157340) in 0.5%BSA/HBSS for 25 min ...
• Propagation of neuronal micronuclei regulates microglial states

  Sarasa Yano, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-CD68 (FA-11, Biolegend, 1:500), anti-Lamin B1 (ab16048 ...
• Ischemic and hemorrhagic stroke lesion environments differentially alter the glia repair potential of neural progenitor cell and immature astrocyte grafts

  Honour O Adewumi, et al., bioRxiv - Neuroscience 2023

  Quote: ... rat anti-P2ry12 (1:100, Biolegend, 848002); rat anti-Pu.1 (1:500 ...
• IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination

  Alejandro Montilla, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-SMI32 (1:1000; #801701 BioLegend) rat anti-CD3 (1:50 ...
• Androgen exposure impairs neutrophil maturation and function within the infected kidney

  Teri N. Hreha, et al., bioRxiv - Immunology 2023

  Quote: ... Ly6G-AlexaFluor 700 (1:800, Biolegend #127621), CD63-APC/Cy7 (1:200 ...
• Androgen exposure impairs neutrophil maturation and function within the infected kidney

  Teri N. Hreha, et al., bioRxiv - Immunology 2023

  Quote: ... CD63-APC/Cy7 (1:200, Biolegend #143908), CXCR4-BUV805 (1:200 ...
• PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

  Payam Gharibani, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Ly6G (1:400; clone 1A8; Biolegend), and anti-Clec12a APC (1:400 ...
• Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination

  Yuhao Li, et al., bioRxiv - Microbiology 2023

  Quote: ... IgD (Biolegend, 11-26c.2a,1:200,), Ter119(Biolegend ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... Ly6C (BV785, Biolegend, 1:200, clone HK1.4), Ly6G (PE-eFlour610 ...
• Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

  Allen L. Pan, et al., bioRxiv - Neuroscience 2023

  Quote: ... or anti-Aβ (1:1,000, Biolegend, 803001). Membranes were washed the next day with 0.1% Tween-20 in PBS followed by incubation in a mixture of secondary antibodies ...
• Selective inhibition of fibroblast-specific Domain Discoidin Receptor 1 (DDR1) reduces collagen deposition and modulates fibroblast-specific cytokine release within the breast microenvironment

  Daniel E.C. Fein, et al., bioRxiv - Cell Biology 2023

  Quote: ... CD4-APC-Cy7 (BioLegend 100413; 1:400). Propidium iodide (1:5000 ...
• Synergistic activity of IL-2 mutein with tolerogenic ImmTOR nanoparticles leads to massive expansion of antigen-specific Tregs and protection against autoimmune disease

  Takashi Kei Kishimoto, et al., bioRxiv - Immunology 2023

  Quote: ... CD3e-BV-510 (BioLegend, clone UCHT-1) and CD26-PE-CF594 (BD clone M-A251) ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-MAP2 (1:500; Biolegend, 822501). Tissue sections were incubated with fluorophore-conjugated secondary antibody solution for 1 hr at room temperature ...
• Early Deprivation Impairs Perforant Pathway Connectivity and Contextual Memory in Adolescent Male Mice

  Rafiad Islam, et al., bioRxiv - Neuroscience 2023

  Quote: ... Phosphorylated Antibody (BioLegend, Cat# 8016021, 1:1000). Number of reelin positive cells was assessed using a mouse anti-reelin antibody (Cat # AB78540-1001 ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... CD206 (AF647, Biolegend, 1:100, clone CO68C2), CD209b (APC ...
• In situ cryo-electron tomography of β-amyloid and tau in post-mortem Alzheimer’s disease brain

  Madeleine A. G. Gilbert, et al., bioRxiv - Pathology 2023

  Quote: ... or 1:750 dilution 4G8 (Biolegend, 803001) and 1:750 dilution AT8 (Thermofisher ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD11c (1:400; BV421; Biolegend #117330), anti-CD86 (1:300 ...
• Androgen exposure impairs neutrophil maturation and function within the infected kidney

  Teri N. Hreha, et al., bioRxiv - Immunology 2023

  Quote: ... CXCR2-PE/Cy7 (1:200, Biolegend #149316). Cells were washed ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD86 (1:300; A647; BioLegend #105020), anti-Siglec-F (1:400 ...
• Proneural genes form a combinatorial code to diversify neocortical neural progenitor cells

  Alexandra Moffat, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit-anti-Pax6 (BioLegend #901301, 1:300), rabbit-anti-Tbr1 (Abcam #ab31940 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Ly6C (1:500; BV780; BioLegend #128041), anti-Ly6G (1:400 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD45 (1:200; BV610; BioLegend #103140), anti-CD169 (1:200 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD11b (1:300; BV650; BioLegend #101239), anti-CD11c (1:400 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... CD69 (1:200 dilution; clone H1.2F3; BioLegend) and CD45 (1:200 dilution ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... CD44 (1:400 dilution; clone IM7, BioLegend), CD69 (1:200 dilution ...
• PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

  Catherine M. Kerr, et al., bioRxiv - Microbiology 2023

  Quote: ... Ly6C (BV785, Biolegend, 1:300, clone HK1.4), Ly6G (PE-efluor610 ...
• PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

  Catherine M. Kerr, et al., bioRxiv - Microbiology 2023

  Quote: ... CD4 (BV605, Biolegend, 1:200, clone GK1.5),CD8a (APC-Cy7 ...
• Influence of Alzheimer’s disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex

  Sang Ho Kwon, et al., bioRxiv - Neuroscience 2023

  Quote: ... clone 6E10 (Biolegend, Cat# 803001, 1:50), rabbit anti-Tau antibody pSer202/pThr205 ...
• Immune memory shapes human polyclonal antibody responses to H2N2 vaccination

  Yuhe R. Yang, et al., bioRxiv - Immunology 2023

  Quote: ... CD27 BV605 (O323, 1:50, BioLegend, RRID:AB_11204431), CD20 APC-Cy7 (2H7 ...
• Single-cell profiling uncovers regulatory programs of pathogenic Th2 cells in allergic asthma

  Matarr Khan, et al., bioRxiv - Immunology 2023

  Quote: ... TGF-β1 (1 ng/ml, BioLegend, 580702). To investigate the induction of a pathogenic program in Th2 cells ...
• IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination

  Alejandro Montilla, et al., bioRxiv - Neuroscience 2023

  Quote: ... Ly6C-PE/Cy7 (1:300; #128017 BioLegend) and SYTOX AADvanced™ Ready Flow™ (Thermo Fisher) ...
• PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

  Catherine M. Kerr, et al., bioRxiv - Microbiology 2023

  Quote: ... CD19 (BV711, Biolegend, 1:400, clone 6D5), CD69 (PE ...
• CD4⁺ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

  Viviana Rubino, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD235a (clone HIR2) (all 1:100; BioLegend), followed by staining with FITC-conjugated streptavidin (1:3000 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... anti-NK1.1 (1:200; BV510; BioLegend #108738), anti-F4/80 (1:100 ...
• Immune Response of Transplanted Kidney Tissues Assembled from Organoid Building Blocks

  Thiago J. Borges, et al., bioRxiv - Bioengineering 2023

  Quote: ... CD123-BV711 (1:20, clone 6H6, Biolegend), CD27-BV650 (1:50 ...