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201 - 250 of 1835 citations for 5 Benzyloxy pyrimidine 2 carbonitrile since 2020

• Cross-Linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model

  Floriana Cremasco, et al., bioRxiv - Immunology 2020

  Quote: ... 2) huCD45 APC Cy7 (BioLegend), huCD3 PerCp-Cy5.5 (BioLegend) ...
• IL-4-induced hysteresis in naïve T cell activation

  Alexandre P. Meli, et al., bioRxiv - Immunology 2020

  Quote: ... CD138 (clone 281-2, Biolegend), B220 (clone RA3-6B2 ...
• The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

  Kanagaraju Ponnusamy, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CD138 (BioLegend; clone: 281-2) and analyzed for germinal center activated B cells (GCB) ...
• Soluble Spike DNA vaccine provides long-term protective immunity against SAR-CoV-2 in mice and nonhuman primates

  Yong Bok Seo, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 PE (Biolegend 503808), CD4 PE-Cy7 (Biolegend 100528) ...
• Soluble Spike DNA vaccine provides long-term protective immunity against SAR-CoV-2 in mice and nonhuman primates

  Yong Bok Seo, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 BV605 (Biolegend 500332), and Live/dead Near-IR (Invitrogen L10119) ...
• Genetic evidence that uptake of the fluorescent analog 2NBDG occurs independently of known glucose transporters

  Lucas J. D’Souza, et al., bioRxiv - Immunology 2021

  Quote: ... or -BV510 (281-2, Biolegend) and B220-BV421 (RA3-6B2 ...
• The dietary fiber guar gum ameliorates experimental autoimmune encephalomyelitis via attenuated Th1 activation and differentiation

  Naomi M Fettig, et al., bioRxiv - Immunology 2022

  Quote: ... CD49d-FITC (R1-2, BioLegend), Tbet-APC (4B10 ...
• Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity

  Jack Polmear, et al., bioRxiv - Immunology 2023

  Quote: ... and CD138 (281-2, BioLegend), while human cells were incubated with CD20 (2H7 ...
• Rationally designed modular STAT-activating scaffolds enforce cell-intrinsic transcriptional programs augmenting the anti-tumor potency of CAR T cells

  Christopher P Saxby, et al., bioRxiv - Bioengineering 2023

  Quote: ... IL-2 (BioLegend, Cat. # 500326), and Perforin (BioLegend ...
• Functional impairment of “helpless” CD8⁺ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

  Verena van der Heide, et al., bioRxiv - Immunology 2024

  Quote: ... and monensin (2 µM; Biolegend). Phorbol 12-myristate13-acetate (PMA)/ionomycin-stimulated (Cell Activation cocktail ...
• Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causes in vitro and in vivo Inflammation

  Neuza Domingues, et al., bioRxiv - Pathology 2023

  Quote: ... CD206 (Biolegend; clone 15-2) and CD163 (Biolegend ...
• Syntenin and CD63 Promote Exosome Biogenesis from the Plasma Membrane by Blocking Cargo Endocytosis

  Yiwei Ai, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse CD63 (NVG-2, Biolegend), CD9 (312102 ...
• Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

  Alastair Copland, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (JES6-5H4; Biolegend), TNFa-BV605 (MP6-XT22 ...
• Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1⁺ macrophages

  Jiangyan Yu, et al., bioRxiv - Immunology 2023

  Quote: ... and CADM1 (2:100, BioLegend) at 37°C for 25 min ...
• Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer

  Loretah Chibaya, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and monensin (2 μM, Biolegend) in a humidified incubator at 37°C with 5% CO2 ...
• Single-cell transcriptomics reveals heterogenous thymic dendritic cell subsets with distinct functions and requirements for thymocyte-regulated crosstalk

  Jayashree Srinivasan, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD63 (NVG-2, Biolegend) and anti-XCR1-AF647 (ZET ...
• The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8⁺ T-cell revitalization

  Andrea Gramatica, et al., bioRxiv - Immunology 2024

  Quote: ... BCL-2 (AF488, 100, Biolegend), anti-ID2 (Pe-Cy7 ...
• MYC and p53 alterations cooperate through VEGF signaling to repress cytotoxic T cell and immunotherapy responses in prostate cancer

  Katherine C. Murphy, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and monensin (2 μM, Biolegend) in a humidified incubator at 37°C with 5% CO2 ...
• MYC and p53 alterations cooperate through VEGF signaling to repress cytotoxic T cell and immunotherapy responses in prostate cancer

  Katherine C. Murphy, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and monensin (2 μM, Biolegend) in a humidified incubator at 37°C with 5% CO2 ...
• Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors

  Eunkyu Sung, et al., bioRxiv - Cell Biology 2024

  Quote: ... 2 U/ml erythropoietin (BioLegend), 25 ng/ml stem cell factor (BioLegend) ...
• Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha

  Zhen Xu, et al., bioRxiv - Biochemistry 2024

  Quote: Human FAP (2 µM, Biolegend) was mixed with 5-fold molar excess of SUMO-I3 sdAb in the binding buffer (100 mM PBS pH 7.2 ...
• Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening

  Dilip Challa, et al., bioRxiv - Bioengineering 2024

  Quote: ... anti-mouse IgG2a/b-FITC (5 μg/ml) anti-mouse CD138-PE (5 μg/ml; BioLegend cat# 142504) and anti-human CD45-APC (Invitrogen cat# MA5-17688) ...
• Co-engagement of TIGIT⁺ immune cells to PD-L1⁺ tumours by a bispecific antibody potentiates T-cell response and tumour control

  Xiaopei Cui, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 secretion was evaluated with the IL-2 assay ELISA kit (Cat#431801, Biolegend). The absorbance value at 450 nm/570 nm was detected by the microplate reader ...
• Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1

  Takeya Masubuchi, et al., bioRxiv - Immunology 2024

  Quote: ... the amount of secreted IL-2 was quantified using Human IL-2 ELISA kit (Biolegend).
• MUCOSECRETORY LUNG DISEASE: DIFFERENT ASSEMBLIES OF JAG1 AND JAG2 DETERMINE TRACHEOBRONCHIAL CELL FATE

  Susan D. Reynolds, et al., bioRxiv - Cell Biology 2022

  Quote: ... and Keratin 5 (BioLegend #905501, 1:2000).
• Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response

  Holly C. Webster, et al., bioRxiv - Immunology 2021

  Quote: ... PE-conjugated anti-IL-5 (TRFK5, BioLegend), e450-conjugated anti-IFNγ (XMG1.2 ...
• BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma

  Y Ishii, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-keratin 5 (Biolegend: 905501, 1:500) in 1% BSA / 4% serum overnight at 4 °C ...
• T Cell Deficiency Precipitates Antibody Evasion and Emergence of Neurovirulent Polyomavirus

  Matthew D. Lauver, et al., bioRxiv - Immunology 2022

  Quote: ... and CD4 (RM4-5) (Biolegend, 1:200). For quantification of in vitro infections ...
• FoxP3 can fold into two distinct dimerization states with divergent functional implications for T cell homeostasis

  Fangwei Leng, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (RM4-5; BioLegend, dilution 1:200), CD25 (PC61 ...
• Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine

  Alexandra Atalis, et al., bioRxiv - Immunology 2022

  Quote: ... and 5 μg/mL Brefeldin A (BioLegend). After 6 h ...
• Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine

  Alexandra Atalis, et al., bioRxiv - Immunology 2022

  Quote: ... and 5 μg/mL Brefeldin A (BioLegend). After 6 h of incubation ...
• Impact of formate supplementation on body weight and plasma amino acids

  Sandeep Dhayade, et al., bioRxiv - Biochemistry 2020

  Quote: ... CD4 (Biolegend, cloneRM4-5, BV605, 1:100), CD8 (BD Bioscience ...
• Immunogenicity and Protective Efficacy of an Intranasal Live-attenuated Vaccine Against SARS-CoV-2 in Preclinical Animal Models

  Jun-Guy Park, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (clone GK1.5; eBioscience, RM4-5, Biolegend), ...
• Antibody-drug conjugates targeting CD45 plus Janus kinase inhibitors effectively condition for allogeneic hematopoietic stem cell transplantation

  Stephen P. Persaud, et al., bioRxiv - Immunology 2020

  Quote: ... with 5 μg/mL Brefeldin A (BioLegend) added to each well for the last 2.5 hours ...
• Cell Programmed Nutrient Partitioning in the Tumor Microenvironment

  BI Reinfeld, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CD4 PerCP-Cy5.5 (RM4-5, BioLegend 100540), Ly6G PerCP-Cy5.5 (1A8 ...
• Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

  Liangxia Ai, et al., bioRxiv - Immunology 2022

  Quote: ... and IL-5 APC (Biolegend, cat.504306), and CD3ε APC/Fire 750 (Biolegend ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... αIL-12 (5 μg/ml; Biolegend, #505307) and αIFNγ (5 ug/ml ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... and αIFNγ (5 ug/ml; Biolegend, #505812), with or without 2.5 μM mCRAMP ...
• Lipidomic Profiling Reveals an Age-Related Deficiency of Skeletal Muscle Proresolving Mediators that Contributes to Maladaptive Tissue Remodeling

  James F. Markworth, et al., bioRxiv - Immunology 2020

  Quote: ... CD64-APC (X54-5/7.1) (BioLegend, 139306), CD11c-APCe780 (N418 ...
• OPTN limits herpes stromal keratitis severity and demyelination through negative regulation of IL-17 and hyperinflammatory T-cell response

  Joshua Ames, et al., bioRxiv - Immunology 2021

  Quote: ... PE Anti-Mouse CD4 [RM4-5] (BioLegend)
• Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging

  Alena Moudra, et al., bioRxiv - Immunology 2020

  Quote: ... 5 μg/ml Brefeldin A (Biolegend, 420601) was added to the culture for the last four hours of the incubation ...
• Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response

  Holly C. Webster, et al., bioRxiv - Immunology 2021

  Quote: ... BV505-conjugated anti-CD4 (RM4-5, BioLegend), FITC-conjugated anti-CD69 (H1.2F3 ...
• Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response

  Holly C. Webster, et al., bioRxiv - Immunology 2021

  Quote: ... BV711-conjugated anti-CD4 (RM4-5, BioLegend), BV421-conjugated anti-CD11b (M1/70 ...
• Extracellular signal-regulated kinase (ERK) pathway control of CD8⁺ T cell differentiation

  Marcos P. Damasio, et al., bioRxiv - Immunology 2020

  Quote: ... Stained with CD4 BV510 (Biolegend RM4-5), CD8 BV421 (Biolegend 53-6.7) ...
• Bifurcated monocyte states are predictive of mortality in severe COVID-19

  Anthony R. Cillo, et al., bioRxiv - Immunology 2021

  Quote: ... and CD36::PE-Cy7 (Biolegend; 5-271). We also used eFluor 780 Fixable Viability Dye (ThermoFisher ...
• IRG1 controls host responses to restrict Mycobacterium tuberculosis infection

  Arnaud Machelart, et al., bioRxiv - Immunology 2022

  Quote: ... APC-coupled RM4-5 (anti-CD4, Biolegend), Brillant violet 421 (BV421)-coupled E50-2440 (anti-SiglecF ...
• Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2

  Samantha R. Mackin, et al., bioRxiv - Microbiology 2022

  Quote: ... CD64 (BV421; clone X54-5/7.1; Biolegend), CD88 (Viogreen ...
• Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis

  Dmitri I. Kotov, et al., bioRxiv - Immunology 2022

  Quote: ... APC-labeled CD64 (X54-5/7.1, BioLegend), and TotalSeq-A-labeled Ly6G (1A8 ...
• STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

  Yulin Wang, et al., bioRxiv - Immunology 2022

  Quote: ... 5 μg/ml soluble αCD28 mAb (BioLegend) plus 200 U/ml IL-2 (Miltenyi Biotec ...
• Thymic macrophages consist of two populations with distinct localization and origin

  Tyng-An Zhou, et al., bioRxiv - Immunology 2022

  Quote: ... or rabbit polyclonal to Keratin 5 (BioLegend) overnight at 4°C in a humidified chamber ...