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151 - 200 of 2493 citations for 5 Bromo 2 Tert Butyldimethylsilyl 4 Methylthiazole since 2020

• Regulatory T cell expansion by a highly CD25-dependent IL-2 mutein arrests ongoing autoimmunity

  Liliane Khoryati, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 immune complex (IL-2ic; mouse recombinant IL-2 + anti-IL-2 (JES6-1A12, BioLegend); molar ratio 2:1 ...
• Mapping the T cell repertoire to a complex gut bacterial community

  Kazuki Nagashima, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (RM4-5, BioLegend), CD3e (145-2C11 ...
• Disruption of Z-RNA–binding of ADAR1 induces Aicardi-Goutières syndrome–like encephalopathy in mice

  Taisuke Nakahama, et al., bioRxiv - Immunology 2020

  Quote: ... CD4 (RM4-5; BioLegend), CD8 (53-6.7 ...
• Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

  Dan Corral, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD8a (53-6.7 ...
• 12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes

  Abhishek Kulkarni, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD80 (16-10A1 ...
• IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

  Holly Bachus, et al., bioRxiv - Immunology 2022

  Quote: ... IL-5 (TRFK5; BioLegend), IL-4 (11B11 ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD44 (IM7 ...
• Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

  Carsten T. Charlesworth, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... CD4 (RM4-5; Biolegend), CD8 (54-6.7 ...
• A ketogenic diet reduces age-induced chronic neuroinflammation in mice

  Mitsunori Nomura, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, BioLegend), CD8 (53-6.7 ...
• Phosphoproteomic analysis of the AKT signalling axis in cutaneous squamous carcinoma progression reveals novel therapeutic targets

  R Button, C Harwood, RFL O’Shaughnessy, bioRxiv - Cancer Biology 2022

  Quote: ... Keratin 5 (BioLegend Poly19055) (1:1,000 WB) ...
• Atheroprone shear stress stimulates noxious endothelial extracellular vesicle uptake by MCAM and PECAM-1 cell adhesion molecules

  Pierre-Michaël Coly, et al., bioRxiv - Cell Biology 2023

  Quote: ... α5 integrin (Biolegend, 921704), α6 integrin (Biolegend ...
• CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

  Amélien Sanlaville, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD4 (RM4-5; Biolegend), NKp46 (29A1.4 ...
• Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

  Jiang Li, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD206 (C068C2 ...
• Interferon-γ Elicits Pathological Hallmarks of ALS in Human Motor Neurons

  Changho Chun, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD44 (C44Mab-5, BioLegend), and CD8 (SK1 ...
• Interferon-sensitized hematopoietic progenitors dynamically alter organismal immunity

  Maria Guillamot, et al., bioRxiv - Immunology 2024

  Quote: ... CD4 (Biolegend RM4/5), CD8 (Biolegend ...
• Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

  Alexander J. Nelson, et al., bioRxiv - Immunology 2024

  Quote: ... IL-4 neutralization was performed using anti-IL-4 (10 µg/mL, clone 11B11, BioLegend) or rat IgG1 isotype control (10 µg/mL ...
• Subset-specific and temporal control of effector and memory CD4+ T cell survival

  Sharmila Shanmuganad, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend), CD127 ...
• Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

  Jacob Gadwa, et al., bioRxiv - Immunology 2024

  Quote: ... Bcl-2 (BioLegend) or Ki67 (BD Bioscience ...
• Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders

  Luca Pagliaroli, et al., bioRxiv - Genomics 2021

  Quote: ... 4 µl of the respective antibodies were used: APC anti-human SSEA-4 antibody (Biolegend, #330417) and PE anti-human TRA-1-60-R antibody (Biolegend ...
• Characterizing the polarization continuum of macrophage subtypes M1, M2a and M2c

  TCL Oates, et al., bioRxiv - Immunology 2022

  Quote: ... with or without the inclusion of interleukin-4 at 20ng/mL (wt/vol, IL-4, BioLegend), interferon-g at 2.5ng/mL (wt/vol ...
• The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin

  Martina Damo, et al., bioRxiv - Immunology 2021

  Quote: ... CTLA-4 (clone UC10-4B9, BioLegend), EpCAM (clone G8.8 ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-TIM-4 (BioLegend, catalog #354003), anti-PD-L1 (also labeled with Dazzle 594 ...
• Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4⁺ regulatory T cells

  Mark Mensink, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CTLA-4-PE-Dazzle594 (BioLegend) and anti-NFATC2-AF488 (Cell Signaling Technology ...
• Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine

  Alexandra Atalis, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (Biolegend, PE/Dazzle 594) and TNF-α (Biolegend ...
• Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy

  Raphael S. Peres, et al., bioRxiv - Immunology 2022

  Quote: ... CTLA-4-PE (clone BNI3, BioLegend), CD39-BV421 (clone A1 ...
• Stearoyl-CoA desaturase mediated monounsaturated fatty acid availability supports humoral immunity

  Xian Zhou, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (10 ng/mL; Biolegend), IL-2 (10 unit/mL ...
• Role of T cells in intrauterine administration of activated peripheral blood mononuclear cells in recurrent implantation failure

  Guillaume Ricaud, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL-4/BV510 (Biolegend, USA), anti-IL-17/BV711 (Biolegend ...
• Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks

  Jacob W. Freimer, et al., bioRxiv - Genomics 2021

  Quote: ... or CTLA-4 (Biolegend, Cat #349908). Cells sorted for IL2RA underwent surface staining according to the manufacturer’s protocol ...
• Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks

  Jacob W. Freimer, et al., bioRxiv - Genomics 2021

  Quote: ... or CTLA-4 (Biolegend, Cat #349908) and analyzed with an Attune NxT Flow Cytometer with a 96-well plate-reader.
• Robust SARS-CoV-2-specific T-cell immunity is maintained at 6 months following primary infection

  J Zuo, et al., bioRxiv - Immunology 2020

  Quote: ... and anti-IL-4-PE (Biolegend). All antibodies were purchased from Biolegend ...
• Expression of Tim-3 drives naïve Treg to an effector-like state with enhanced suppressive activity

  Hridesh Banerjee, et al., bioRxiv - Immunology 2020

  Quote: ... CTLA-4 clone UC10-4B9 (BioLegend), CD103 clone M290 (BD) ...
• Acute lymph node slices are a functional model system to study immunity ex vivo

  Maura C. Belanger, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (ELISA MAX standard, Biolegend) and TNFα (R&D Systems ...
• CTLA-4 tail fusion enhances CAR-T anti-tumor immunity

  Xiaoyu Zhou, et al., bioRxiv - Immunology 2023

  Quote: ... or anti-CTLA-4 antibody (Biolegend) at 37°C for 1 hour ...
• Selective Inhibition of Interleukin-2 Inducible T Cell Kinase (ITK) Enhances Anti-Tumor Immunity in Association with Th1-skewing, Cytotoxic T cell Activation, and Reduced T Cell Exhaustion

  Lih-Yun Hsu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-human IL-4 (OA19A66, Biolegend) and anti-human IL-5 (TRFK5 ...
• Human cerebrospinal fluid single exosomes in Parkinson’s and Alzheimer’s diseases

  Koya Yakabi, et al., bioRxiv - Neuroscience 2023

  Quote: ... Aquaporin-4 (E5206) (BioLegend catalog #600352), CD11b (M1/70 ...
• A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

  Kristin Metzdorf, et al., bioRxiv - Immunology 2024

  Quote: ... CD11a (M17/4, BioLegend, CA, USA), CD62L (MEL-14 ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse IL-4 (11B11, Biolegend) and anti-mouse IFNγ (XMG1.2 ...
• Membrane positioning across antigen-induced synaptic contacts tunes CAR-T cell signaling and effector responses

  Fenglei Li, Kaushik Choudhuri, bioRxiv - Immunology 2023

  Quote: ... with 100ng/ml hIL-4 (Biolegend) 2days post transduction ...
• Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

  Liangxia Ai, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 PE (Biolegend, cat.504104), and IL-5 APC (Biolegend ...
• Melanoma-intrinsic NR2F6 activity regulates anti-tumor immunity

  Hyungsoo Kim, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and V5-tag (7/4, Biolegend).
• PPAR-γ regulates the effector function of human T_H9 cells by promoting glycolysis

  Nicole L. Bertschi, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (50 ng/ml) (BioLegend) for TH2 cells ...
• Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2

  Robert M Johnson, et al., bioRxiv - Microbiology 2023

  Quote: ... IL-4 BV605 (BioLegend, clone: 11B11), and IL-17a BV711 (BioLegend ...
• Initial TCR Signal Strength Imprints GATA3 and Tbet Expression Driving T-helper Cell Fate Decisions

  Mohammad Ameen Al-Aghbar, et al., bioRxiv - Immunology 2024

  Quote: ... PE/Cy7-IL-4 (11B11, Biolegend), PerCP-Cy5.5-IFNγ (XMGL2 ...
• IL-1β Signalling Modulates T Follicular Helper and Regulatory Cells in Human Lymphoid Tissues

  Romain Vaineau, et al., bioRxiv - Immunology 2024

  Quote: ... CTLA-4 (BV605, 1/40, BioLegend), PD-1 (PE-Cy5.5 ...
• Limiting mitochondrial-derived ATP transfer to the cytosol enhances T-cell activation

  Omri Yosef, et al., bioRxiv - Immunology 2024

  Quote: ... and IL-4 (Biolegend, BLG-431104) cytokines using enzyme-linked immunosorbent assay (ELISA).
• Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia

  Lawrence J. Dooling, et al., bioRxiv - Bioengineering 2024

  Quote: ... or interleukin-4 (IL4, BioLegend 574302) to polarize to M1 and M2 states ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and cultured in presence of IL-2 (2 ng/ml; Biolegend), IL-7 (2.5 ng/ml ...
• Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8⁺ T cells to suppress anti-tumor immunity

  Joanne D. Tejero, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/mL recombinant mouse interleukin-2 (IL-2) (BioLegend); additionally ...
• Tissue environment, not ontogeny, defines intestinal intraepithelial T lymphocytes

  Alejandro Brenes, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 [clone RM4-5 (BioLegend)] ...
• A third vaccination with a single T cell epitope protects against SARS-CoV-2 infection in the absence of neutralizing antibodies

  Iris N. Pardieck, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (clone RM4-5, BioLegend), CD8 (clone 53-6.7 ...