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101 - 150 of 361 citations for 3 3 Bromomethyl phenyl thiophene since 2020

• Targeting GFPT2 to reinvigorate immunotherapy in EGFR-mutated NSCLC

  Luyao Ao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Panel 3: BV421-conjugated CD45 (1:100, 103133, Biolegend), PE/Cy7 conjugated F4/80 (1:100 ...
• FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats

  Peter Aldiss, et al., bioRxiv - Physiology 2024

  Quote: ... anti-galectin-3 (cat. 125402, Biolegend, San Diego, CA), alpha-smooth muscle action (α-SMA ...
• PP2A catalytic subunit alpha is critically required for CD8⁺ T cell homeostasis and anti-bacterial responses

  Xian Zhou, et al., bioRxiv - Immunology 2024

  Quote: ... Alexa fluor 700-labeled anti-CD8β (Lyt-3; Biolegend), BV650-labeled anti-CD45.1 (Ly5.1 ...
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1⁺ macrophages

  Jiangyan Yu, et al., bioRxiv - Immunology 2023

  Quote: ... Then cells were stained with CCR7 (3:100, BioLegend) and CADM1 (2:100 ...
• A microbiota-derived metabolite instructs peripheral efferocytosis

  Pedro H. V. Saavedra, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml recombinant annexin V (BioLegend, 640901) for 1 hour at 4 °C ...
• Type 1 interferon remodels normal and neoplastic hematopoiesis in human

  Chhiring Lama, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 2 or 3 (TotalSeq-A, clone LNH-94, Biolegend) for GoT-IM ...
• Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

  Aidan M. Tousley, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... TIM-3 (BV510 or BV650, Clone F38-2E2, BioLegend), LAG-3 (PE ...
• Prox2+ and Runx3+ neurons regulate esophageal motility

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Tubulin β-3 (BioLegend, Poly18020, 1:1000), goat anti-CTb (List Labs ...
• Human effector CD8⁺ T cells with an exhausted-like phenotype control tumor growth in vivo in a humanized tumor model

  Juliane Mietz, et al., bioRxiv - Immunology 2024

  Quote: ... Galectin-9-PE-Cy7 (Biolegend, 9M1-3, Cat. 348916), TIGIT-APC-Cy7 (Biolegend ...
• LAG-3 blockade reactivates the CD8⁺ T cell expansion program to re-expand contracted clones in the tumor

  Munetomo Takahashi, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-LAG-3 (clone C9B7W, BioLegend or Selleck) was injected intraperitoneally at a dose of 200 μg per mouse on days 14 and 16 (for bulk RNA-seq data ...
• Broad-spectrum RNA antiviral inspired by ISG15^-/- deficiency

  Yemsratch T. Akalu, et al., bioRxiv - Immunology 2024

  Quote: ... or with anti-cleaved caspase-3 antibody (Biolegend 559341) for quantification by flow cytometry.
• Cancer-associated adipocytes mediate CD8⁺T cell dysfunction via FGF21-driven lipolysis

  Sumiya Dalangood, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-TIM-3-PE/Cy7 (cat#134009, CloneB8.2C12, Biolegend), anti-LAG3-Percp/Cyanine5.5 (cat#125211 ...
• Catabolism of extracellular glutathione supplies amino acids to support tumor growth

  Fabio Hecht, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 3 µL of Annexin V-FITC (Biolegend 0640906). Then ...
• Spermidine/spermine N1-acetyltransferase controls tissue-specific regulatory T cell function in chronic inflammation

  Teresa Neuwirth, et al., bioRxiv - Immunology 2024

  Quote: ... Each patient was also stained with one of TotalSeq™-C0251/2/3/4 Antibody (Biolegend, Cat: 394661/3/5/7, 1:100) for sample multiplexing ...
• BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

  Yunlong Cao, et al., bioRxiv - Immunology 2022

  Quote: ... 3 μL PE/Cyanine7 anti-human IgM antibody (BioLegend, 314532), 0.0052 μg biotinylated Ovalbumin (SinoBiological ...
• CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected Cells

  Minh Ma, et al., bioRxiv - Immunology 2021

  Quote: ... FITC anti-human CD223 (LAG-3) antibody (clone 11C3C65, BioLegend), BV510 anti-human CD314 (NKG2D ...
• FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

  Célia Jeronimo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-Rpb3 (Neoclone W0012, 3 μL; BioLegend 665004, 1.5 μL), anti-Flag (Sigma-Aldrich F3165 ...
• Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

  Tomokazu S. Sumida, et al., bioRxiv - Immunology 2020

  Quote: ... The following antibodies were used: anti-LAG-3 (11C3C65, BioLegend), anti-PD-1 (EH12.1 ...
• Efficacy of Targeting SARS-CoV-2 by CAR-NK Cells

  Minh Ma, Saiaditya Badeti, Ke Geng, Dongfang Liu, bioRxiv - Immunology 2020

  Quote: ... FITC anti-human CD223 (LAG-3) antibody (clone 11C3C65, BioLegend), BV510 anti-human CD314 (NKG2D ...
• Profound Treg perturbations correlate with COVID-19 severity

  Silvia Galván-Peña, et al., bioRxiv - Immunology 2020

  Quote: ... CD127 AF488 (clone A019D5, BioLegend, cat# 351314, dilution 3:100); CD25 PE-Cy7 (clone BC96 ...
• CD8+ T cell epitope variations suggest a potential antigen presentation deficiency for spike protein of SARS-CoV-2

  Congling Qiu, et al., bioRxiv - Immunology 2021

  Quote: ... washed for 3 times with Washing Buffer (BioLegend Cat#421601) and blocked with Dilution Buffer (0.5M Tris pH 8.0 ...
• Cell-Intrinsic and Extrinsic Effects of Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia

  Fei Fei, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cells were incubated with PE-Galectin-3 (Biolegend cat# 126706) or matched isotype control for 15 mins and analyzed on BD Accuri C6 cytometer (BD Biosciences ...
• Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas

  Julie Stockis, et al., bioRxiv - Immunology 2024

  Quote: ... injection of 3 µg anti-CD45.2-PE (clone 104, Biolegend) antibody 3 min prior to sacrifice ...
• Activity-dependent development of the body’s touch receptors

  Celine Santiago, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Tubulin beta 3 (TUBB3) (Biolegend #Poly18020, 1:500), rabbit anti-S100 Beta (VWR/Protein Tech #15146-1-AP ...
• Early infection response of the first trimester human placenta at single-cell scale

  Regina Hoo, et al., bioRxiv - Genomics 2023

  Quote: ... TotalSeq™-B0253 anti-human Hashtag 3 Antibody (394635, Biolegend), TotalSeq™-B0254 anti-human Hashtag 4 Antibody (394637 ...
• Interleukin-1 receptor antagonist is a conserved driver of tuberculosis

  Dmitri I. Kotov, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-mouse TotalSeq-A Hashtag antibody (1-3; BioLegend). The stained T cell samples were then incubated with Sytox Green Dead Cell Stain (Thermo Fisher Scientific ...
• Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s Disease

  Rikesh M. Rajani, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Tubulin beta 3 (clone TUJ1; 1:1,000; BioLegend; 801202), IBA1 (1:500 ...
• Targeting CXCR4 with [²¹²Pb/²⁰³Pb]-Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer

  Keegan A. Christensen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 3×106 cells were stained with Zombie Aqua (423102, BioLegend) for 20 min at room temperature for live/dead cells discrimination ...
• Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas

  Amy Y. Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TIM-3 BV711 (clone RMT3-23, Biolegend 119727, 1:200), Foxp3 FITC (clone FJK-16s ...
• Prostacyclin as a Negative Regulator of Angiogenesis in the Neurovasculature

  Tasha R Womack, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rat antibody against Notch 3 intracellular domain was obtained from Biolegend. Blots were probed with a mouse anti-actin (ThermoFisher ...
• Intracellular sterol sensing controls intestinal B cell differentiation

  Bruno C. Trindade, et al., bioRxiv - Immunology 2021

  Quote: ... Color development was stopped with 3 M H2SO4 stop solution (Biolegend). Purified mouse IgA (Southern Biotech ...
• Proteome and functional decline as platelets age in the circulation

  Harriet E. Allan, et al., bioRxiv - Cell Biology 2021

  Quote: Platelet subpopulations (3 × 106) stained with CD42b-BV421 (1:300; Biolegend) in (i ...
• The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding

  Monica L. Husby, et al., bioRxiv - Microbiology 2022

  Quote: ... Cells were blocked with 3% BSA/PBS cell staining buffer (BioLegend) and incubated at 37°C for 2 hours ...
• The challenge of distinguishing cell-cell complexes from singlet cells in non-imaging flow cytometry and single-cell sorting

  Julie G Burel, et al., bioRxiv - Immunology 2020

  Quote: ... 3 μl of anti-human CD3-AF700 antibody (clone UCHT1, Biolegend) and 1 μl of anti-human CD14-PE antibody (clone 61D3 ...
• MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection

  Sharon Khuzwayo, et al., bioRxiv - Immunology 2020

  Quote: ... and 1:50 of anti-TIM-3 BV785 (F38-2E2, BioLegend). Tetramer staining was performed in the dark at room temperature for 40 minutes ...
• Mitochondrial respiration contributes to the interferon gamma response in antigen presenting cells

  Michael C. Kiritsy, et al., bioRxiv - Immunology 2020

  Quote: ... CD40 (APC anti-mouse CD40 Antibody, Clone 3/23 Biolegend 124611), or PD-L1 (APC anti-mouse CD274 (B7-H1 ...
• Profound Treg perturbations correlate with COVID-19 severity

  Silvia Galván-Peña, et al., bioRxiv - Immunology 2020

  Quote: ... CD25 PE-Cy7 (clone BC96, BioLegend, cat# 302611, dilution 3:100); KLRG1 APC-Cy7 (clone 2FI/KLRG1 ...
• A minimal-complexity light-sheet microscope maps network activity in 3D neuronal systems

  Paulina M Wysmolek, et al., bioRxiv - Neuroscience 2022

  Quote: ... and anti-Tubulin ß 3 antibody (Clone Tuj1, BioLegend, MMS-435P) respectively.
• Inhibition of Acyl-CoA Synthetase Long Chain Isozymes Decreases Multiple Myeloma Cell Proliferation and Causes Mitochondrial Dysfunction

  Connor S. Murphy, et al., bioRxiv - Cancer Biology 2024

  Quote: ... washed 3 times with Cell Staining Buffer (BioLegend, Cat. No. 420201) and stained with APC-Annexin V (1:20 ...
• Noise-induced changes in rat head stability and orientation correlate with dysfunction of otolith irregular afferents

  Mamiko Niwa, et al., bioRxiv - Neuroscience 2023

  Quote: ... or rabbit anti-tubulin beta 3 (Tubb3, 1:1000, BioLegend Poly18020), and rabbit anti-myosin 7a (Myo7a ...
• Effective NGN2-based neuronal programming of hiPSCs in an automated microfluidic platform

  S Angiolillo, S Micheli, O Gagliano, bioRxiv - Neuroscience 2022

  Quote: ... and mouse anti-TUBULIN β 3 (βIIITUBB) (1:5000, 801202 BioLegend) and MAP2 (1:10000 ...
• ZEB2 regulates the development of CD11c+ atypical B cells

  Xin Gao, et al., bioRxiv - Immunology 2022

  Quote: ... in the presence of 3 μg/ml anti-CD40 antibody (Biolegend) w/wo 50 ng/mL IL-21 ...
• The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube

  Isabel Zhang, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 3 µM CHIR99021 (Axon) and 10 ng/ml mouse LIF (BioLegend)) ...
• A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies

  Sungwon An, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-Tubulin β 3 (TUBB3)-AF647 1:300 (BioLegend 801210) overnight and counter stained with DAPI ...
• Identification of small molecule enhancers of NK cell tumoricidal activity via a tumor microenvironment-mimicking co-culture assay

  Aylin Binici, et al., bioRxiv - Immunology 2024

  Quote: ... and TIM-3(F38-2E2)-APC-Fire 750 (BioLegend (San Diego)) ...
• Slow kinesin-dependent microtubular transport facilitates ribbon synapse assembly in developing cochlear inner hair cells

  Roos Anouk Voorn, et al., bioRxiv - Neuroscience 2024

  Quote: ... and anti-β-3-tubulin (Tuj-1; Mouse IgG2a, BioLegend, #801202) and a fluorescently-conjugated nanobody directed against PSD-95 (Fluo-Tag-X2 ...
• Flotillin-2 dampens T cell antigen-sensitivity and functionality

  Sookjin Moon, et al., bioRxiv - Immunology 2024

  Quote: ... and TotalSeq™-A0303 anti-mouse Hashtag 3 Antibody (Biolegend, 155805).
• PU.1 and MYC transcriptional network defines synergistic drug responses to KIT and LSD1 inhibition in acute myeloid leukemia

  Brittany M. Smith, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Chromium Next GEM Single Cell 3’ Reagent v3.0 Kit (Biolegend, 10X Genomics). Libraries were sequenced on a HiSeq2500 (Illumina ...
• Single-cell RNA sequencing reveals functional heterogeneity and sex differences of glioma-associated brain macrophages

  Natalia Ochocka, et al., bioRxiv - Cancer Biology 2020

  Quote: ... For intracellular antigens the following anti-mouse Galectin 3 (M3/38 BioLegend) was used.).