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801 - 850 of 2015 citations for 4 Chloro 2 fluoro 3' 4 methylpiperazinomethyl benzophenone since 2020

• Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche

  Aidan E. Gilchrist, Brendan A.C. Harley, bioRxiv - Bioengineering 2020

  Quote: ... recombinant murine MMP-3 (#552704, BioLegend), recombinant murine c-RP (#50409-M08H ...
• Cell-Intrinsic and Extrinsic Effects of Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia

  Fei Fei, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Galectin-3 (Biolegend, San Diego, USA), phospho-ERK1/2 ...
• Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses

  Yang Li, et al., bioRxiv - Immunology 2022

  Quote: ... Tim-3 (BioLegend, 119721, RMT3-23), LAG-3 (BioLegend ...
• Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

  Yaeko Nakajima-Takagi, et al., bioRxiv - Immunology 2022

  Quote: ... recombinant mouse IL-3 (575506; Biolegend), and recombinant murine GM-CSF (315-03 ...
• Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa

  Maria E. Mercau, et al., bioRxiv - Immunology 2022

  Quote: ... Galectin-3 (BioLegend clone M3/38), CD11c (BioLegend clone N418) ...
• Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

  Sharon Yunger, et al., bioRxiv - Immunology 2022

  Quote: ... FITC-LAG-3 (clone 11C3C65, BioLegend) APC-CD25 (clone BC96 ...
• Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy

  Raphael S. Peres, et al., bioRxiv - Immunology 2022

  Quote: ... LAG-3-PE (clone C9B7W, Biolegend), RORgT-BV421 (clone Q31-378 ...
• Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy

  Raphael S. Peres, et al., bioRxiv - Immunology 2022

  Quote: ... GATA-3-AF647 (clone 16E10A23, BioLegend), RORgT-PE (clone AFKJS-9 ...
• The OSUMMER lines: a series of ultraviolet-accelerated NRAS-mutant mouse melanoma cell lines syngeneic to C57BL/6

  Brandon M. Murphy, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lag-3 (Biolegend #C9B7W; 1:250), CD3 (BD Biosciences #145-2C11 ...
• Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity

  Johannes Textor, et al., bioRxiv - Immunology 2023

  Quote: ... 20 ng/mL IL-3 (Biolegend), 50 ng/mL IL-6 (Biolegend) ...
• Emergence and suppressive function of Tr1 cells in glomerulonephritis

  Shiwa Soukou-Wargalla, et al., bioRxiv - Immunology 2023

  Quote: ... CD366 (TIM-3) (BV 421, BioLegend, clone RMT3-23 ...
• Tregs constrain CD8⁺ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy

  Joseph R. Palmeri, et al., bioRxiv - Immunology 2023

  Quote: ... αTIM-3-BV785 (RMT3-23, Biolegend), αTCF1/TCF7-AF488 (C63D9 ...
• The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate lysosomal stress responses

  Tomoya Eguchi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-galectin-3 [M3/38] (BioLegend), anti-α-tubulin [DM1A] (Sigma) ...
• Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice

  Tuancheng Feng, Huan Du, Fenghua Hu, bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Galectin-3 (BioLegend, 126702), rabbit anti-TFE3 (Sigma ...
• Dendritic cell targeting in lymph nodes with engineered modular adapters improves HAdV5 and HC-HAdV5 tumor vaccination by co-secretion of IL-2v and IL-21

  Fabian Weiss, et al., bioRxiv - Biochemistry 2024

  Quote: ... anti-muCD40 (BioLegend clone 3/23), anti-muDEC205 (BioLegend clone NLDC-145) ...
• Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors

  Eunkyu Sung, et al., bioRxiv - Cell Biology 2024

  Quote: ... 25 ng/ml IL-3 (BioLegend), 25 ng/ml IL-6 (BioLegend) ...
• UBA1-CDK16: A Sex-Specific Chimeric RNA and Its Role in Immune Sexual Dimorphism

  Xinrui Shi, et al., bioRxiv - Genomics 2024

  Quote: ... Antibodies were added to stain surface markers for 30 min at 4°C (CD3 PE, Life Technologies; CD8 FITC, Life Technologies; CD11b AF700, Life Technologies CD19 PerCP-Cy5.5, BioLegend; C33 BV605, BioLegend; CD56 BV711, BD). After 30min ...
• Regulatory T cell expansion by a highly CD25-dependent IL-2 mutein arrests ongoing autoimmunity

  Liliane Khoryati, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 immune complex (IL-2ic; mouse recombinant IL-2 + anti-IL-2 (JES6-1A12, BioLegend); molar ratio 2:1 ...
• LRRK2-dependent Rab GTPase phosphorylation in response to endolysosomal damage depends on macrophage differentiation

  Susanne Herbst, Maximiliano G. Gutierrez, bioRxiv - Cell Biology 2020

  Quote: ... anti-Galectin-3-AF647 (125408) from BioLegend and anti-CHMP4B (13683-1-AP ...
• The RAG1 Ubiquitin Ligase Domain Enhances the Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity

  Thomas N. Burn, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml anti-CD28 (Biolegend) in RPMI with 10% FBS ...
• The antimicrobial peptide cathelicidin is critical for the development of Th17 responses in severe inflammatory disease

  Katie J Smith, et al., bioRxiv - Immunology 2022

  Quote: ... and rTGFβ (3 ng/ml; Biolegend, #580706), with or without 2.5μM mCRAMP ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... and rTGFβ (3 ng/ml; Biolegend, #580706), with or without 2.5 μM mCRAMP for 1 to 3 days ...
• Disruption of augmin-mediated microtubule nucleation in neural stem cells causes p53-dependent apoptosis and aborts brain development

  Ricardo Viais, et al., bioRxiv - Cell Biology 2020

  Quote: ... β3-tubulin (Biolegend #801201, dilution 1:1000), cleaved caspase-3 (Novus Biologicals #MAB835 ...
• Opposing roles of Granzymes A and B in the immune response to intestinal infection

  Maud Vandereyken, et al., bioRxiv - Immunology 2021

  Quote: ... [clone 1D4B (BioLegend)] and CD107b (Mac-3) [clone M384 (BioLegend)].
• Systematic functional screening of chromatin factors identifies strong lineage and disease dependencies in normal and malignant haematopoiesis

  D Lara-Astiaso, et al., bioRxiv - Genomics 2022

  Quote: ... CD55 (PE-conjugated; clone RIKO-3; Biolegend), CD41 (APC-conjugated ...
• Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

  Sharon Yunger, et al., bioRxiv - Immunology 2022

  Quote: ... FITC-TIM-3 (clone F38-2E2, BioLegend), FITC-LAG-3 (clone 11C3C65 ...
• The transcription factor IRF-5 is essential for the metabolic rewiring of CD8 T cells during chronic infection

  Linh Thuy Mai, et al., bioRxiv - Immunology 2024

  Quote: ... anti TIM-3-BV605 (RMT3-23, Biolegend), anti CD44-PE-Cy7 (IM7 ...
• Novel populations of Tr1 cells contribute to the resolution of acute influenza A virus infection

  Caitlin A Abbott, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-mouse LAG-3 (C9B7W, Biolegend), which were stained for 60 min at 37°C as previously described (Gagliani et al. ...
• Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations

  Aisha Souquette, et al., bioRxiv - Immunology 2023

  Quote: ... Panel 3) CD3-AF700 (Biolegend Cat. 300323), CD4-APC Fire750 (Biolegend Cat ...
• Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers

  Isaac Dean, et al., bioRxiv - Immunology 2023

  Quote: ... IgG2b BV605 or R718 (R12-3, BioLegend), IL-7Rα BV605 or BV421 (AFR34 ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Galectin-3 (1:1000; Biolegend, 125401), anti-γ-H2AX (1:200 ...
• Novel inhibitors of acute, axonal DLK palmitoylation are neuroprotective and avoid the deleterious side effects of cell-wide DLK inhibition

  Xiaotian Zhang, et al., bioRxiv - Neuroscience 2024

  Quote: ... β3 tubulin (mouse, BioLegend, TUJ1, #MMS-435P), myc (rabbit ...
• Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer

  Yijuan Zhang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PE anti-mouse CD366 (Tim-3) (Biolegend), PE/Cy7 anti-mouse CD279 (PD-1 ...
• SOX2-induced IL1α-mediated immune suppression drives epithelial dysplasia malignant transformation

  Hülya F. Taner, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Tim-3 (clone RMT3-23, BioLegend), anti-TCRγ/δ (clone GL3 ...
• Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs

  Marion David, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LAG-3 and TGFBR2 (Biolegend, Amsterdam, Netherlands). For TILs characterization ...
• Subset-specific and temporal control of effector and memory CD4+ T cell survival

  Sharmila Shanmuganad, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend), CD127 ...
• Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

  Jacob Gadwa, et al., bioRxiv - Immunology 2024

  Quote: ... Bcl-2 (BioLegend) or Ki67 (BD Bioscience ...
• Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

  Or-Yam Revach, et al., bioRxiv - Cancer Biology 2024

  Quote: ... T cells were activated for 3 days using 3 μg anti-human CD3 and CD28 antibodies (Biolegend, 300438, 377604) and 50 ng/mL of IL-2 (Peprotech ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and cultured in presence of IL-2 (2 ng/ml; Biolegend), IL-7 (2.5 ng/ml ...
• Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8⁺ T cells to suppress anti-tumor immunity

  Joanne D. Tejero, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/mL recombinant mouse interleukin-2 (IL-2) (BioLegend); additionally ...
• Non-productive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immunity responses

  Julia Kazmierski, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-TIM-3/CD366-FITC (#345022; Biolegend). To determine ACE2 cell surface expression ...
• Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μL PE/Cyanine7 anti-IgM(Biolegend, 314532), and fluorophore-labelled Receptor-Binding Domain (RBD ...
• Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μL FITC anti-CD20 Antibody (Biolegend, 302304), 3.5 μL Brilliant Violet 421 anti-CD27 Antibody (Biolegend ...
• Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μL FITC anti-CD19 Antibody (Biolegend, 392508), 3 μL FITC anti-CD20 Antibody (Biolegend ...
• In vivo analysis of Trypanosoma cruzi persistence foci at single cell resolution

  Alexander I. Ward, et al., bioRxiv - Microbiology 2020

  Quote: ... Antibodies against β-tubulin-3 (Biolegend, Cat#802001), CD45 (Tonbo Biosciences ...
• A P2rx7 passenger mutation affects the vitality and function of immune cells in P2X4ko and other transgenic mice

  Marco Er-Lukowiak, et al., bioRxiv - Immunology 2020

  Quote: ... and recombinant IL-3 (10 ng/ml, Biolegend). BMMCs were transferred into a new petri dish with new BMMC medium every 3-4 days ...
• Overcoming microenvironment-mediated chemoprotection through stromal galectin-3 inhibition in acute lymphoblastic leukemia

  Somayeh S. Tarighat, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and galectin-3 (#125402, Biolegend, San Diego, CA), were diluted 1:1000 or 1:2000 in 5% BSA and incubated for 1hour at room temperature ...
• Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia

  Diego Gilioli, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD223 (LAG-3) BV605 (cat#369324 from BioLegend), CD3 BUV737 (cat#565466 from BD) ...
• Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia

  Diego Gilioli, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD366 (TIM-3) BV421 (cat#345008 from BioLegend), CD223 (LAG-3 ...
• Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

  Julia Prigann, et al., bioRxiv - Microbiology 2023

  Quote: ... and anti-TIM-3/CD366-FITC (#345022; Biolegend). For intracellular immunostaining ...