Labshake search

3701 - 3750 of 8657 citations for 6 Chloro 2 3 4 9 tetrahydro 1H pyrido 3 4 b indol 1 one since 2019

• KAT6A deficiency impairs cognitive functions through suppressing RSPO2/Wnt signaling in hippocampal CA3

  Yongqing Liu, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1×EDTA-free protease inhibitor (Roche), and 60 U/mL RNasin Plus RNase Inhibitor (Promega ...
• Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism

  Ellen Hertz, et al., bioRxiv - Neuroscience 2024

  Quote: ... Colcemid (1:100, Cat.# 10295892001, Roche) was added ...
• Alternative translation initiation by ribosomal leaky scanning produces multiple isoforms of the Pif1 helicase

  Tomas Lama-Diaz, Miguel G. Blanco, bioRxiv - Molecular Biology 2024

  Quote: ... eGFP (mouse 1:2000, 11814460001, Roche) and Pgk1-HRP (mouse ...
• Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic niche

  Yasmin Henlon, et al., bioRxiv - Immunology 2024

  Quote: ... 1 unit of Liberase TL (Roche) and 0.6 mg DNAse enzymes ...
• Age-dependent RGS5 loss in pericytes induces cardiac dysfunction and fibrosis in the heart

  Anita Tamiato, et al., bioRxiv - Physiology 2023

  Quote: ... and 1% Pen/Strep (11074440001, Roche).
• CRISPR/Cas9-mediated deletion of a kinetoplast-associated gene attenuates virulence in Leishmania major parasites

  Fatemeh Darzi, et al., bioRxiv - Immunology 2024

  Quote: ... 1 U HiFi enzyme mix (Roche), 1X buffer ...
• A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation

  Jessica E. Fellmeth, et al., bioRxiv - Genetics 2023

  Quote: ... rat anti-HA (Roche, 1:50), mouse anti-C(3)G (1:500 ...
• Single nuclei transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration

  Simon Perrin, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 1% collagenase D (11088866001, Roche). Cells in suspension were removed every 20 min and digestion medium was replaced ...
• The gut contractile organoid: a novel model for studying the gut motility regulated by coordinating signals between interstitial cells of Cajal and smooth muscles

  Rei Yagasaki, et al., bioRxiv - Developmental Biology 2024

  Quote: ... in 1% blocking regent (Roche, 1096176)/PBS ...
• CRISPR/Cas9-mediated deletion of a kinetoplast-associated gene attenuates virulence in Leishmania major parasites

  Fatemeh Darzi, et al., bioRxiv - Immunology 2024

  Quote: ... 1 U HiFi enzyme mix (Roche), 1X buffer (Roche ...
• Caspase-8-mediated CYLD Cleavage boosts LPS-induced Endotoxic Shock

  Jianling Liu, et al., bioRxiv - Immunology 2024

  Quote: ... 1× proteinase inhibitor cocktail (Roche, 5056489001), 2□mM PMSF ...
• Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity

  R. Doolan, et al., bioRxiv - Immunology 2024

  Quote: ... DNase 12.5 U mL−1 (Roche, Sigma-Aldrich ...
• Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates

  Zhaowei Meng, et al., bioRxiv - Biochemistry 2024

  Quote: ... supplemented with 1% protease inhibitors (Roche). The cellular lysates were centrifuged at 12,000 rpm for 10 min at 4°C and the soluble fraction was collected ...
• Structural basis of substrate transport and drug recognition by the human thiamine transporter SLC19A3

  Florian Gabriel, et al., bioRxiv - Biochemistry 2024

  Quote: ... 1 × EDTA-free protease inhibitors (Roche), 0.5 mM TCEP ...
• The potato resistance protein Rx1 multimerizes upon activation by the Coat Protein of PVX

  Marijn Knip, Emy Latul, Frank LW Takken, bioRxiv - Plant Biology 2023

  Quote: ... 1 x protease inhibitors (Roche®). Beads were pelleted using a magnetic separator ...
• Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology

  Yuichi Morozumi, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-HA (1:2000; 12CA5, Roche) and anti-GFP (1:2500 ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-GFP (1:200, 11814460001, Roche), anti-GFP (1:500 ...
• Robust genetic analysis of the X-linked anophthalmic (Ie) mouse

  Brianda Areli Hernandez-Moran, et al., bioRxiv - Genetics 2022

  Quote: ... 1 μl DNAase-free RNase (Roche) was used to remove remaining RNA ...
• zDHHC5 expression is increased in cardiac hypertrophy and reduced in heart failure but this does not correlate with changes in substrate palmitoylation

  Alice Main, et al., bioRxiv - Biochemistry 2022

  Quote: ... HA-tag (1:5000, Roche, 11867423001). The secondary antibodies used were as follows ...
• The Kelch13 compartment is a hub of highly divergent vesicle trafficking proteins in malaria parasites

  Sabine Schmidt, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat a-HA (1:2000) (Roche), rabbit anti-aldolase (1.2000 ...
• Germ granule association drives small RNA specificity for a nuclear Argonaute protein

  Shihui Chen, Carolyn M. Phillips, bioRxiv - Molecular Biology 2023

  Quote: ... anti-HA 1:500 (Roche, 11867423001), anti-Myc 1:100 (Thermo Fisher ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HA (11867423001, Roche, rat, 1:1000); HA (sc-7392 ...
• Interaction of PINK1 with nucleotides and kinetin

  Zhong Yan Gan, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 1× cOmplete Protease Inhibitor Cocktail (Roche) and 1× PhosSTOP (Roche) ...
• Complex-specific subunits of endosomal tethering factors determine the balance between HOPS/CORVET complexes

  Ármin Sőth, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-HA (Roche, rat, 1:1000), anti-Vps18 (Abcam ...
• Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons

  Julia Ryvkin, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-GFP (1:100, Roche), Rabbit anti-Dh44 (0.6:100) ...
• From asexuality to sexual reproduction: cyclical switch of gametogenic pathways in hybrids depends on ploidy level

  Dmitrij Dedukh, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... diluted in 1% blocking reagent (Roche) on 1× PBS for 1h at RT ...
• Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors

  Fay Cooper, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1× Complete protease inhibitor cocktail (Roche) and 250 U Benzonase nuclease immediately before use ...
• SWI/SNF chromatin remodeling determines brassinosteroid-induced transcriptional activation

  Tao Zhu, et al., bioRxiv - Plant Biology 2023

  Quote: ... 1× Complete Protease Inhibitor Cocktail (Roche)) ...
• A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling

  Rosalie E Lawrence, et al., bioRxiv - Biochemistry 2022

  Quote: ... 1× cOmplete protease inhibitor cocktail (Roche)) ...
• Structure and DNA bridging activity of the essential Rec114–Mei4 trimer interface

  Kaixian Liu, et al., bioRxiv - Biochemistry 2023

  Quote: ... 1× Complete protease inhibitor tablet (Roche) and 0.1 mM phenylmethanesulfonyl fluoride (PMSF ...
• A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling

  Rosalie E Lawrence, et al., bioRxiv - Biochemistry 2022

  Quote: ... 1× cOmplete protease inhibitor cocktail (Roche)) ...
• KRAB zinc finger proteins ZNF587/ZNF417 protect lymphoma cells from replicative stress-induced inflammation

  Filipe Martins, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1 mM Phenylmethylsulfonylfluoride (Roche, Basel, Switzerland), 1% octyl-beta-D glucopyranoside (Sigma-Alrich) ...
• Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation

  Lisa Maria Metz, et al., bioRxiv - Cell Biology 2022

  Quote: ... and DAPI (#10236276001, Roche, 1:3000) was used ...
• Calcium flux through ER-TGN contact sites facilitates cargo export

  Bulat R. Ramazanov, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-GFP (1:1000, 11814460001, Roche). The membrane was washed 3 times with 5% milk TBST and incubated with HRP-conjugated secondary antibodies (1:5000 ...
• Signaling Node at TSC2 S1365 Potently Regulates T-Cell Differentiation and Improves Adoptive Cellular Cancer Therapy

  Chirag H Patel, et al., bioRxiv - Immunology 2023

  Quote: ... 1× protease inhibitors (Roche, Basel, Switzerland)) and lysed at 4 °C for 30 min ...
• Defective callosal termination underlies the long-term behavioral deficits in NMDA receptor antibody encephalitis mouse model

  Jing Zhou, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 phosSTOP phosphatase inhibitor tablet (Roche)) with Dounce homogenizer on ice ...
• SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid drug

  Maria Laura Sosa Ponce, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 1:1,000 mouse αGFP (Roche, 11814460001), 1:500 mouse αPgk1 (Molecular Probes) ...
• Assembling membraneless organelles from de novo designed proteins

  Alexander T. Hilditch, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... 1 tablet cOmplete protease inhibitor (Roche), and lysed by sonication on ice (3 s on ...
• Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish Melanoma

  Bruno Lopes-Bastos, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 1% blocking solution (#11096176001, Roche) for 3 minutes at 85°C ...
• Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

  Iqbal Dulloo, et al., bioRxiv - Cell Biology 2022

  Quote: ... HA-HRP (Roche, #11867423001; 1:2000), KDEL (AbCam ...
• A novel ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma

  Alexander E. P. Loftus, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-GFP (Roche; #11814460001, 1:1000), anti-EGFR (Millipore ...
• Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

  Ken Yamada, et al., bioRxiv - Biochemistry 2023

  Quote: ... 1 mM EDTA + protease inhibitors (Roche) + 1mM NaF + 1mM Na3VO4 and sonicated for 10 seconds.
• Zinc is Essential for the Copper Reductase Activity of Yeast Nucleosomes

  Maria Vogelauer, et al., bioRxiv - Biochemistry 2023

  Quote: ... 1 µg DNase-free RNase (Roche) was added and reacted for 30 minutes at 30°C ...
• Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome

  Antto J. Norppa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 1 µg/µL yeast RNA (Roche), 1 U/µL RiboLock RNase inhibitor (Thermo Scientific) ...
• Extensive remodelling of XIST regulatory networks during primate evolution

  Emmanuel Cazottes, et al., bioRxiv - Genomics 2023

  Quote: ... 1× complete protease inhibitor cocktail (Roche). Cells were de-crosslinked in 0,5% SDS in PBS1X at 37°C for 1h on a thermomixer under agitation ...
• Inducible degradation-coupled phosphoproteomics identifies PP2A^Rts1 as a novel eisosome regulator

  Andrew G. DeMarco, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-GFP (1:1,000; Roche). The following secondary antibodies and dilutions were used for 1 hour at room temperature ...
• Intracranial tumors elicit systemic sympathetic hyperactivity that limits immunotherapeutic responses

  Selena J. Lorrey, et al., bioRxiv - Immunology 2023

  Quote: ... 0.2mg ml-1 Dnase I (Roche) in HBSS with calcium and magnesium ...
• Planar cell polarity is essential for the architectural patterning of the mammalian biliary tree

  Michaela Raab, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 phosphoSTOP phosphatase inhibitor tablet (Roche), 1 ml glycerol and 1.9 ml dH2O) ...
• Cryo-EM structure of the Spo11 core complex bound to DNA

  You Yu, et al., bioRxiv - Biochemistry 2023

  Quote: ... 1× Complete protease inhibitor tablet (Roche) and 0.1 mM phenylmethylsulfonyl fluoride (PMSF ...
• A screen of alkaline and oxidative formulations for their inactivation efficacy of metal surface adsorbed prions using a steel-bead seed amplification assay

  Daniel Heinzer, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 1 mM 1,4-dithiothreitol (Roche) were added prior to boiling the samples at 95 °C for 10 minutes and centrifugation at 2’000 rpm for 5 minutes ...