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3601 - 3650 of 8657 citations for 6 Chloro 2 3 4 9 tetrahydro 1H pyrido 3 4 b indol 1 one since 2019

• Targeted Proteomics Reveals Quantitative Differences in Low Abundance Glycosyltransferases of Patients with Congenital Disorders of Glycosylation

  Roman Sakson, et al., bioRxiv - Biochemistry 2020

  Quote: ... supplemented with 1 % protease inhibitor (Roche) mix and 1 μL benzonase (250 units/μL ...
• Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model

  Liyu Chen, et al., bioRxiv - Neuroscience 2021

  Quote: ... with 1× protease inhibitor cocktail (Roche) for 20 min on ice ...
• Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals

  Charles Ducrot, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-HA (1:500; Roche). To improve the immunoreactivity of some synaptic markers ...
• Transcriptomic encoding of sensorimotor transformation in the midbrain

  Zhiyong Xie, et al., bioRxiv - Neuroscience 2021

  Quote: ... Fab fragments (1:400, Roche, 11207733910) at 4°C for 30 h ...
• P4HA2 is associated with prognosis, promotes proliferation, invasion, migration and EMT in glioma

  Jing Lin, et al., bioRxiv - Cancer Biology 2020

  Quote: ... wst-1 reagent (Roche, Basel, Switzerland) was added to each well and incubated for 1 h ...
• Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing

  Fiona Jenkinson, et al., bioRxiv - Cell Biology 2021

  Quote: ... : anti-Myc 1:10,000 (9E10, Roche, Cat no ...
• A hetero-oligomeric remorin-receptor complex regulates plant development

  Nikolaj B. Abel, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1 x Protease Inhibitor Cocktail (Roche) and 0.5 % (v/v ...
• A hetero-oligomeric remorin-receptor complex regulates plant development

  Nikolaj B. Abel, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1 x Protease Inhibitor Cocktail (Roche) and 1 % (v/v ...
• A hetero-oligomeric remorin-receptor complex regulates plant development

  Nikolaj B. Abel, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1 x Protease Inhibitor Cocktail (Roche) and 1 % (v/v ...
• Microarray screening reveals a non-conventional SUMO-binding mode linked to DNA repair by non-homologous end-joining

  Maria Jose Cabello-Lobato, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-GFP (11814460001, Roche, 1:1,000), anti-XLF (ab33499 ...
• A novel RAB11-containing adaptor complex anchoring myosin-5 to secretory vesicles

  Mario Pinar, et al., bioRxiv - Cell Biology 2021

  Quote: α-HA rat mAb (1/1,000) (Roche) as primary antibody ...
• Cdc14 activates autophagy to regulate spindle pole body dynamics during meiosis

  Wenzhi Feng, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1× Protease Inhibitor Cocktail (Roche, 11873580001), 1 mM PMSF] ...
• A pair of transporters controls mitochondrial Zn²⁺ levels to maintain mitochondrial homeostasis

  Tengfei Ma, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1 mM PMSF (phenylmethylsulfonyl fluoride) (Roche) and purified with Glutathione Sepharose 4B beads (GE Healthcare ...
• A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for diagnosis of glanders infections

  Guanbo Wang, et al., bioRxiv - Microbiology 2020

  Quote: ... and protease inhibitors (1 tablet, Roche) were added and the mixture was incubated for 15 min ...
• Oxicam-type nonsteroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway

  Nobuaki Ishihama, et al., bioRxiv - Plant Biology 2020

  Quote: ... anti-HA (1:5,000; 12013819001; Roche), anti-Myc (1:1,000 ...
• The PIF1-MIR408-Plantacyanin Repression Cascade Regulates Light Dependent Seed Germination

  Anlong Jiang, et al., bioRxiv - Plant Biology 2020

  Quote: ... and 1× protease inhibitor mixture (Roche). Immunoblotting was performed with an anti-GFP antibody (Abcam) ...
• Targeted single-cell RNA-seq identifies minority cell types of kidney distal nephron that regulate blood pressure and calcium balance

  Lihe Chen, Chun-Lin Chou, Mark A. Knepper, bioRxiv - Systems Biology 2020

  Quote: ... Dispase II (1.2U ml-1, Roche), 7.5 mg/ml B ...
• Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

  Aditya S. Paul, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-GFP (Roche, 1:1000). Shield-1 (Shld1 ...
• Identification and antimicrobial properties of bacteria isolated from naturally decaying wood

  Tanja R. Scheublin, et al., bioRxiv - Microbiology 2020

  Quote: ... 1× buffer (Roche Diagnostics, Mannheim, Germany), 0.6 μM of each primer and 200 μM of each deoxynucleoside triphosphate in a total volume of 25 μL ...
• Ustilago maydis serves as a novel production host for the synthesis of plant and fungal sesquiterpenoids

  Jungho Lee, et al., bioRxiv - Microbiology 2020

  Quote: ... -HA (monoclonal, Roche; 1:4,000 dilution), -Myc (monoclonal ...
• Myosin 10 and a Cytoneme-Localized Ligand Complex Promote Morphogen Transport

  Eric T. Hall, et al., bioRxiv - Cell Biology 2020

  Quote: ... rat anti-HA (1:250; Roche), mouse anti-CD63 (E-12 ...
• Single-Molecule Dynamics of SARS-CoV-2 5’ Cap Recognition by Human eIF4F

  Hea Jin Hong, et al., bioRxiv - Biophysics 2021

  Quote: ... 1× EDTA-free protease inhibitor (Roche), 1× PMSF ...
• Col6a1⁺/CD201⁺ mesenchymal cells regulate intestinal morphogenesis and homeostasis

  Maria-Theodora Melissari, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1 mg/ml Dispase II (Roche) and 100 U/ml Dnase I (Sigma-Aldrich ...
• A Van Gogh/Vangl tyrosine phosphorylation switch regulates its interaction with core Planar Cell Polarity factors Prickle and Dishevelled

  Ashley C. Humphries, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GFP (Roche 7.1&13.1 1:1000), Myc (SCBT 9E10 1:1000) ...
• Shoc2 controls ERK1/2-driven neural crest development by balancing components of the extracellular matrix

  Rebecca G. Norcross, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Fab fragments 1:2,000 (Roche, #11093274910). Signal was detected using NBT:BCIP (1.38:1.0 ratio ...
• Sexual deprivation induces a CRF independent stress response and decreases resistance to stressors in Drosophila via a subpopulation of Neuropeptide F receptor-expressing neurons

  Julia Ryvkin, et al., bioRxiv - Animal Behavior and Cognition 2022

  Quote: ... mouse anti GFP (1:100, Roche), Rabbit anti Dh44 (0.6:100) ...
• EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance

  Loretah Chibaya, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 1 mg/ml Collagenase A (Roche) for LUAD tumors or Collagenase V (Sigma-Aldrich ...
• ABA signaling prevents phosphodegradation of the Arabidopsis SR45 splicing factor to negatively autoregulate inhibition of early seedling development

  Rui Albuquerque-Martins, et al., bioRxiv - Plant Biology 2022

  Quote: ... and 1 tablet of PHOSSTOP (Roche). The extract was centrifuged at 18,000 g for 10 minutes at 4 °C and the protein content of the supernatant determined using the Bradford method (Bio-Rad ...
• Quantitative imaging reveals PI3Kδ inhibition reduces rhinovirus-induced damage of small airway epithelia in ex vivo cultured human precision cut lung slices from COPD patients

  Dmytro Dvornikov, et al., bioRxiv - Pathology 2022

  Quote: ... For WST-1 assay (Roche, 1644807) 200 µL of the working reagent was added per slice and incubated for 45 min in the incubator ...
• Fission yeast Smi1p participates in the synthesis of the primary septum by regulating β-1,3-glucan synthase Bgs1p function

  Kriti Sethi, et al., bioRxiv - Cell Biology 2022

  Quote: ... or HA (1:5000, Roche Diagnostics). Peroxidase conjugated -rabbit or -mouse secondary antibodies (Jackson Laboratories ...
• The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families

  Yichen Zhong, et al., bioRxiv - Biochemistry 2022

  Quote: ... 1× cOmplete® protease inhibitor (Roche). After clarification (30 min at 20,000 × g at 4°C) ...
• Inversion of a topological domain leads to restricted changes in its gene expression and affects inter-domain communication

  Rafael Galupa, et al., bioRxiv - Genomics 2022

  Quote: ... 1 × complete protease inhibitor cocktail (Roche) for 15min on ice ...
• Synthetic glabridin derivatives mitigate steatohepatitis in a diet-induced biopsy-confirmed non-alcoholic steatosis hepatitis mouse model through paraoxonase-2

  Gu-Choul Shin, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... and 1× phosphatase inhibitor (PhosSTOP, Roche)) ...
• Insights into calcium signaling and gene expression in astrocytes uncovered with 129S4 Slc1a3-2A-CreERT2 knock-in mice

  Lech Kaczmarczyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:200 (clone: 3F10, Roche, AB_2314622) and the respective marker antibody ...
• The Dystonia Gene THAP1 Controls DNA Double Strand Break Repair Choice

  Kenta Shinoda, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and anti-GFP (1:500, Roche).
• OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

  Daisuke Oikawa, et al., bioRxiv - Cell Biology 2021

  Quote: ... and HA (11867423001, Roche; 1:2,000) were also used ...
• The evolution of Sox gene repertoires and regulation of segmentation in arachnids

  Luis Baudouin-Gonzalez, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Counterstaining with DAPI (1:2000; Roche) was carried out for 5-10 minutes ...
• A novel essential RNA-binding protein complex in Trypanosoma brucei

  Kathrin Bajak, et al., bioRxiv - Molecular Biology 2020

  Quote: ... the YFP tag (Roche, 1:1000) and aldolase (rabbit ...
• Structural and functional characterization of the Spo11 core complex

  Corentin Claeys Bouuaert, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1× Complete protease inhibitor tablet (Roche) and 0.1 mM phenylmethanesulfonyl fluoride (PMSF)) ...
• Bryophyte spermiogenesis occurs through multimode autophagic and nonautophagic degradation

  Takuya Norizuki, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1× cOmpleteTM protease inhibitor cocktail (Roche), and 1% (w/v ...
• Lamellipodia-like actin networks in cells lacking WAVE Regulatory Complex

  Frieda Kage, et al., bioRxiv - Cell Biology 2021

  Quote: ... GFP (Roche; #1814460; 1:2,000 dilution), Hem1 (home-made rabbit polyclonal ...
• Antagonistic modules, SIB1 and LSD1, regulate photosynthesis-associated nuclear genes via GOLDEN2-LIKE transcription factors in Arabidopsis

  Mengping Li, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1 × cOmplete protease inhibitor cocktail (Roche), 1 mM PMSF ...
• Gating transitions and modulation of a hetero-octameric AMPA glutamate receptor

  Danyang Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1× Protease Inhibitor (Roche, Cat# 05056489001). Insoluble material was then removed by ultracentrifugation (41,000 rpm ...
• A cell-ECM mechanism for connecting the ipsilateral eye to the brain

  Jianmin Su, et al., bioRxiv - Neuroscience 2021

  Quote: ... or anti-Fl (1:2000, Roche) antibodies followed by fluorescent staining with Tyramide Signal Amplification system (PerkinElmer) ...
• Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila

  Hilary Scott, et al., bioRxiv - Neuroscience 2022

  Quote: ... rat anti-HA (1:1000, Roche) The following secondary antibodies were used ...
• Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with hyperphagocytosis and inflammatory neurodegeneration

  Rodney M. Ritzel, et al., bioRxiv - Neuroscience 2022

  Quote: ... Collagenase/Dispase (1 mg/mL; Roche), and Papain (25 U ...
• A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development

  Andrea Wilderman, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Roche Long Template Buffer 1 (Roche Applied Bioscience ...
• Positive feedback loop of regulating ERK phosphorylation in mESCs mediated by Etv5-Tet2-Fgfr2 axis

  Chen Fan, et al., bioRxiv - Developmental Biology 2019

  Quote: ... with 1×protease inhibitor cocktail (Roche). When phosphorylated proteins were detected ...
• Neuronal-specific function of hTim8a in Complex IV assembly provides insight into the molecular mechanism underlying Mohr-Tranebjærg syndrome

  Yilin Kang, et al., bioRxiv - Cell Biology 2019

  Quote: ... 1 X complete protease inhibitor (Roche)) ...
• P38α Regulates Expression of DUX4 in Facioscapulohumeral Muscular Dystrophy

  L. Alejandro Rojas, et al., bioRxiv - Developmental Biology 2019

  Quote: ... containing 1% RNAse inhibitor (Roche, #03335399001) and 1% DNAse I (ThermoFisher ...