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3301 - 3350 of 8657 citations for 6 Chloro 2 3 4 9 tetrahydro 1H pyrido 3 4 b indol 1 one since 2019

• Glass confers rhabdomeric photoreceptor identity in Drosophila, but not across all metazoans

  F. Javier Bernardo-Garcia, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and digoxigenin (1:50, Roche). To detect the first probe ...
• The nucleolar DExD/H protein Hel66 is involved in ribosome biogenesis in Trypanosoma brucei

  Majeed Bakari-Soale, et al., bioRxiv - Microbiology 2021

  Quote: ... 1 × Protease Inhibitor Cocktail (Roche)) ...
• Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells

  Inês Caldeira Brás, et al., bioRxiv - Neuroscience 2021

  Quote: ... GFP (1:1000, 11814460001, Roche), Glial Fibrillary Acidic Protein (GFAP ...
• Cryo-electron tomography reveals structural insights into the membrane binding and remodeling activity of dynamin-like EHDs

  Arthur A. Melo, et al., bioRxiv - Biophysics 2021

  Quote: ... 1 µM DNase I (Roche)) and lysed in a microfluidizer ...
• The non-genomic vitamin D pathway links β-amyloid to autophagic apoptosis in Alzheimer’s disease

  Rai-Hua Lai, et al., bioRxiv - Neuroscience 2021

  Quote: Colorimetric WST-1 assay (Roche) was used to determine cell viability ...
• SETD2 negatively regulates cell size through its catalytic activity and SRI domain

  Thom M. Molenaar, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1× protease inhibitor cocktail (Roche) and 1x phosphatase inhibitor cocktail (Sigma Aldrich ...
• Disorder is a critical component of lipoprotein sorting in Gram-negative bacteria

  Jessica El Rayes, et al., bioRxiv - Biochemistry 2021

  Quote: ... DNase I (1 mg; Roche), 1 mg RNase A (Thermo Scientific) ...
• OsbZIP62/OsFD7, a functional ortholog of Flowering Locus D (FD), regulates floral transition and panicle development in rice

  Amarjot Kaur, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1% protease inhibitor cocktail (Roche), 10 mM DTT ...
• BnaA03.WRKY28, interacting with BnaA09.VQ12, acts as a brake factor of activated BnWRKY33-mediated resistance outburst against Sclerotinia sclerotiorum in Brassica napus

  Ka Zhang, et al., bioRxiv - Plant Biology 2021

  Quote: ... and 1 × protease inhibitor (Roche)) and incubated with 25 μL GFP-Trap®-MA (Chromotek ...
• Direct contribution of skeletal muscle mesenchymal progenitors to bone repair

  Julien Anais, et al., bioRxiv - Physiology 2020

  Quote: ... 1% collagenase D (11088866001, Roche) and incubated in a water bath at 37°C for 2 hours ...
• Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes

  Timothy J. Durham, et al., bioRxiv - Genomics 2020

  Quote: ... 1× protease inhibitor cocktail (Roche), 1:2,500 superasin (Ambion) ...
• Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline

  Jaryd R. Sullivan, et al., bioRxiv - Microbiology 2021

  Quote: ... 1 x protease inhibitors (Roche), 7 M urea ...
• COP9 signalosome is an essential and druggable parasite target that regulates protein degradation

  Swagata Ghosh, et al., bioRxiv - Microbiology 2020

  Quote: ... and 1 mM PMSF (Roche). Lysate was sonicated and briefly cleared at 800g for 5 minutes ...
• Inhibition of the ubiquitin-proteasome system by a bioactivatable compound

  Tatiana A. Giovannucci, et al., bioRxiv - Cell Biology 2021

  Quote: ... WST-1 tetrazolium salt (Roche) was added and incubated for 1 hour at 37°C ...
• The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

  Carlos Gomez-Diaz, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1 mM PMSF (Roche, 10837091001), 10 mM NEM (Sigma-Aldrich ...
• Cells protect chromosome-microtubule attachments, independent of biorientation, using an Astrin-PP1 and CyclinB-CDK1 feedback loop

  Duccio Conti, et al., bioRxiv - Cell Biology 2020

  Quote: ... GFP (Roche; 1181446001; 1:800), mCherry (Thermo Scientific ...
• iPLA₂-VIA is required for healthy aging in neurons, muscle, and female germline in Drosophila melanogaster

  Surya Banerjee, et al., bioRxiv - Cell Biology 2021

  Quote: ... and DAPI (1:4000, Roche) for 20 min at room temperature ...
• AGO1 regulates pericentromeric regions in mouse embryonic stem cells

  Madlen Müller, et al., bioRxiv - Cell Biology 2022

  Quote: ... HA (Roche 3F10, 1:2000).
• Neural Activation in the Olfactory Epithelium of the East African Cichlid (Haplochromis chilotes) in Response to Odorant Exposure

  Riki Kawamura, Masato Nikaido, bioRxiv - Neuroscience 2022

  Quote: ... Fab fragments (1:80, Roche), amplified using TSA Plus Biotin kit (PerkinElmer ...
• Kaposi’s sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs

  James C. Murphy, et al., bioRxiv - Microbiology 2022

  Quote: ... 1 × protease inhibitor cocktail (Roche)] for 45 minutes ...
• CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation

  Avnish Patel, et al., bioRxiv - Molecular Biology 2022

  Quote: ... with 1× protease inhibitors (Roche). Samples were gently vortexed and incubated on ice for 10 min followed by centrifugation at 12,000g for 10 min at 4°C ...
• CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation

  Avnish Patel, et al., bioRxiv - Molecular Biology 2022

  Quote: ... with 1× protease inhibitors (Roche). Samples were gently vortexed and incubated on ice for 10 min followed by centrifugation at 12,000g for 10 min at 4°C ...
• Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

  Anna S. Nam, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 1 mM ATP (Roche) in a final volume of 11.5 μL of 1X CutSmart buffer ...
• Aberrant association of chromatin with nuclear periphery induced by Rif1 leads to mitotic defect and cell death

  Yutaka Kanoh, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 1× protease-inhibitor cocktail (Roche), and 0.1 mM MG-132 ...
• Polypyrimidine Tract-Binding Protein 1 (PTBP1) regulates CD4 T cell Activation independent of its role in proliferation

  Bitha Narayanan, et al., bioRxiv - Immunology 2022

  Quote: ... 1× Protease inhibitor cocktail (Roche), 1 mM Sodium ortho-vanadate ...
• Hallucinating protein assemblies

  B. I. M. Wicky, et al., bioRxiv - Biophysics 2022

  Quote: ... and 1 mM PMSF (Roche Diagnostics ...
• START domain mediates Arabidopsis GLABRA2 transcription factor dimerization and turnover independently of homeodomain DNA binding

  Thiya Mukherjee, et al., bioRxiv - Plant Biology 2022

  Quote: ... Anti-GFP (1:2000;11814460001, Roche) served as the primary Ab ...
• Cis-membrane association of human ATG8 proteins N-terminus mediates autophagy

  Wenxin Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1× Complete protease inhibitor (Roche) and 1× PhosSTOP (Roche) ...
• The Formation of a Stable Sliding Clamp Discriminates MSH2-MSH3 and MSH2-MSH6 Mismatch Interaction

  Brooke M. Britton, et al., bioRxiv - Biochemistry 2021

  Quote: ... 1 nM anti-dig (Roche), and stated [NaCl] ...
• Insights into calcium signaling and gene expression in astrocytes uncovered with 129S4 Slc1a3-2A-CreERT2 knock-in mice

  Lech Kaczmarczyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:100 (Roche, RRID: AB_390919), RPS21 1:100 (Bethyl ...
• Expression of mini-G proteins specifically halt cognate GPCR trafficking and intracellular signalling

  Yusman Manchanda, et al., bioRxiv - Cell Biology 2021

  Quote: ... with 1% protease inhibitor (Roche) and 1% phosphatase inhibitor cocktail (Sigma-Aldrich) ...
• ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1

  Cyril Statzer, et al., bioRxiv - Physiology 2021

  Quote: ... GFP (1:1’000, Roche #11814460001), Cystathionase/CTH (1:2000 ...
• Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation

  Jibin Sadasivan, et al., bioRxiv - Microbiology 2022

  Quote: ... α-GFP (1:1000, Roche). α-CrPV-VP2 (1:1000 ...
• DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments

  Max A. B. Haase, et al., bioRxiv - Genetics 2022

  Quote: ... and 1 protease tablet (Roche) and lysed with a French press ...
• Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

  Robert Jansen, et al., bioRxiv - Microbiology 2019

  Quote: ... and 1 mM NADH (Roche) at 37°C in triplicate ...
• LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is altered in Townes-Brocks Syndrome

  Laura Bozal-Basterra, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-GFP (Roche, 1:1,000), anti-GAPDH (Proteintech ...
• A dCas9/CRISPR-based targeting system identifies a central role for Ctf19 in kinetochore-derived suppression of meiotic recombination

  Lisa-Marie Kuhl, et al., bioRxiv - Genetics 2020

  Quote: ... α-GFP (Roche; 1:1000).
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... GFP (Roche 11814460001, 1:1000), Cep57 (Genetex GTX115931 ...
• Synergy and allostery in ligand binding by HIV-1 Nef

  Abdullah Aldehaiman, et al., bioRxiv - Biophysics 2020

  Quote: ... 1 tablet protease inhibitor (Roche), 1% triton and 0.4 mg/ml lysozyme ...
• The lonely fish is not a loner fish: whole-brain mapping reveals abnormal activity in socially isolated zebrafish

  Hande Tunbak, et al., bioRxiv - Neuroscience 2020

  Quote: ... Fab fragments (Roche, 1:3000) and TSA Plus Cyanine 3 System (Perkin Elmer ...
• Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

  Alexander Buschle, et al., bioRxiv - Cell Biology 2019

  Quote: ... 1 × proteinase inhibitor cocktail (Roche)) ...
• Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival

  Oana Kubinyecz, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1 mM dNTP mix (Roche)) and incubated on a thermocycler for 60 min at 42°C ...
• The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

  Carlos Gomez-Diaz, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1 mM PMSF (Roche, 10837091001) and 10 mM NEM (Sigma-Aldrich ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... HA (Roche 11867423001, 1:1000), RFP (Rockland 600-401-379S ...
• Dynamic assembly of the calcium hemostasis modulator 1 channel gates ATP permeation

  Yue Ren, et al., bioRxiv - Biochemistry 2021

  Quote: ... 1× protease inhibitor cocktail (Roche), and solubilized in 1% (w/v ...
• Chromatin accessibility analysis uncovers regulatory element landscape in prostate cancer progression

  Joonas Uusi-Mäkelä, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 1× protease inhibitors (Roche, cOmplete)) was added to pre-cooled petri dish and sections were moved from tube to petri dish with 1 ml of lysis buffer ...
• Protein kinase signalling at the Leishmania kinetochore captured by XL-BioID

  Vincent Geoghegan, et al., bioRxiv - Biochemistry 2021

  Quote: ... and 1 tablet PhosSTOP (Roche). Lysates were sonicated with a microtip sonicator on ice for 3 rounds of 10 seconds each at an amplitude of 30 ...
• The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex

  Mashun Onishi, Koji Okamoto, bioRxiv - Cell Biology 2021

  Quote: ... GFP (1:1000, Roche, 13921700), HA (1:5,000 ...
• Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

  Samantha L. Bell, et al., bioRxiv - Microbiology 2020

  Quote: ... HA (Roche, 11867423001; 1:1000), LC3 (Invitrogen ...
• Targeted high-resolution chromosome conformation capture at genome-wide scale

  Damien J. Downes, et al., bioRxiv - Genomics 2020

  Quote: ... 1× cOmplete protease inhibitor (Roche) then pelleted by centrifugation (15 min ...