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4101 - 4150 of 6398 citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• RNA binding is essential for NONO condensates to modulate pre-mRNA processing of super enhancer-associated genes in neuroblastoma

  Song Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1 × protease inhibitor cocktail (Merck, 04693132001) and 2 U SUPERase-In RNase inhibitor (Thermofisher ...
• TGF-β1 induced S100 family protein expression is associated with epithelial to mesenchymal transition states and poor survival in pancreatic cancer

  Ronnie Ren Jie Low, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 1 mL of chloroform (Merck Milipore) was added into each tube ...
• Activation of the actin/MRTF-A/SRF signalling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation

  Lídia Faria, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 1 % Penincilin/Streptomycin (Merck, 15070-063) and 1:1 Supplement B-27 Minus Vitamine A (Gibco,12587-010) ...
• Regulation of adult neurogenesis and neuronal differentiation by Neural Cell Adhesion Molecule 2 (NCAM2)

  Alba Ortega-Gascó, et al., bioRxiv - Neuroscience 2022

  Quote: ... Anti-NeuN (MAB377, Merck, 1:1000); Anti-Sox2 (ab97959 ...
• Prediction of sex-determination mechanisms in avian primordial germ cells using RNA-seq analysis

  Kennosuke Ichikawa, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 1× EmbryoMAX nucleosides (Merck, Darmstadt, Germany), 1× MEM Non-Essential Amino Acids Solution (Thermo Fisher Scientific) ...
• Localization of planteose hydrolysis during seed germination of Orobanche minor

  Atsushi Okazawa, et al., bioRxiv - Plant Biology 2021

  Quote: ... and 1 % Protease Inhibitor Cocktail (Merck) was added and incubated for 5 min ...
• Prions induce minor genome-wide translational changes in neurons compared to glia

  Claudia Scheckel, et al., bioRxiv - Neuroscience 2020

  Quote: ... NeuN (1:250, Merck Millipore, ABN78); PV (1:500 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Vimentin (1:100, Merck, Darmstadt, Germany). Actin labeling were performed with Alexa 488-conjugated Phalloidin (1:100 ...
• Oropouche virus glycoprotein topology and cellular requirements for virus assembly

  Natalia S. Barbosa, et al., bioRxiv - Microbiology 2022

  Quote: ... or 1 µM monensin (Merck M5273) and cells were incubated for a further 6 h before the supernatant and cell lysates were harvested and processed as described above (“After drugs”).
• MOV10 facilitates messenger RNA decay in an N6-methyladenosine (m⁶A) dependent manner to maintain the mouse embryonic stem cells state

  Majid Mehravar, et al., bioRxiv - Biochemistry 2022

  Quote: ... 1% of nucleoside mix (Merck Millipore), 1000 U/mL recombinant leukemia inhibitory factor (LIF/ESGRO ...
• Morphological profiling of human T and NK lymphocytes identifies actin-mediated control of the immunological synapse

  Yolla German, et al., bioRxiv - Immunology 2020

  Quote: ... 1 and 2.5 µM Jasplakinolide (Merck), 0.1 ...
• A chemical tool for improved culture of human pluripotent stem cells

  Laurence Silpa, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-KI-67 (1:400, Merck), anti-Tra-1-60 PE (conjugated ...
• Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

  Sandrina Martens, et al., bioRxiv - Pathology 2020

  Quote: ... and Laminin (1/25, L9393, Merck). After primary antibody incubation ...
• Loss of SORCS2 is associated with neuronal DNA double-strand breaks

  Katerina O. Gospodinova, et al., bioRxiv - Neuroscience 2021

  Quote: ... and GAPDH (1:10,000; MAB374, Merck) diluted in blocking solution overnight at 4°C ...
• JN403, an alpha-7-nicotine-acetylcholine-receptor agonist, reduces alpha-synuclein induced inflammatory parameters of in vitro microglia but fails to attenuate the reduction of TH positive nigral neurons in a focal alpha-synuclein overexpression mouse model of Parkinson’s disease

  Bolam Lee, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:1000 (Merck Millipore; Darmstadt, Germany). On the next day ...
• Loss of the Er81 Transcription Factor in Cholinergic Cells Alters Striatal Activity and Habit Formation

  Yadollah Ranjbar-Slamloo, et al., bioRxiv - Neuroscience 2020

  Quote: ... Goat anti-ChAT (Merck; 1:500), Mouse anti-Lhx6 (Santa Cruz Biotechnology ...
• Enhanced RhoA signaling stabilizes E-cadherin in migrating epithelial monolayers

  Shafali Gupta, et al., bioRxiv - Cell Biology 2021

  Quote: ... pMRLC (Merck Millipore AB3381; 1:50) and Myosin IIA (Biolegend 909801 ...
• The superior salinity tolerance of wheat cultivar Shanrong No. 3 cannot be attributed to elevated Ta-sro1 poly(ADP-ribose) polymerase activity

  Sarah Vogt, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1× protease inhibitor cocktail (Merck #P9599), 0.2% NP-40] at a ratio of 2 mL buffer per 1 g leaf material ...
• Multi-Pathway DNA Double-Strand Break Repair Reporters Reveal Extensive Cross-Talk Between End-Joining, Single Strand Annealing, and Homologous Recombination

  Bert van de Kooij, et al., bioRxiv - Molecular Biology 2021

  Quote: ... MouseαBRCA2 (Merck-Millipore OP95, 1:500), MouseαRad52 (Santa-Cruz sc-365341 ...
• De Novo Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome, an Animal Model for Severe/Critical COVID-19

  Sandro Andreotti, et al., bioRxiv - Genomics 2021

  Quote: ... mixed with 1 ml chloroform (Merck) and centrifuged for phase separation ...
• α-catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity-dependence

  Abhishek Mukherjee, et al., bioRxiv - Cell Biology 2021

  Quote: ... E-cadherin (1:300, Merck, #U3254), α-actinin (1:500 ...
• Ubiquitin proteomics reveals critical targets of the Nse1 RING domain in rDNA and genome stability

  Eva Ibars, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000 (v/v) Benzonase (Merck) was added and further incubated for 1 hour at 37 C ...
• TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

  Xiaochen Fan, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1 % (v/v) nucleosides (100X, Merck) and 10 mil U/mL ESGRO® mouse leukaemia inhibitory factor (Merck ...
• In-cell structures of a conserved supramolecular array at the mitochondria-cytoskeleton interface in mammalian sperm

  Miguel Ricardo Leung, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1% benzonase (Merck Millipore, Darmstadt, Germany), 1 mM sodium orthovanadate ...
• A saturating mutagenesis CRISPR-Cas9 mediated functional genomic screen identifies cis- and trans- regulatory elements of Oct4 in murine ESCs

  Matthew C. Canver, et al., bioRxiv - Genomics 2020

  Quote: ... 1% of nucleoside mix (Merck Millipore), 1000 U/ml recombinant leukemia inhibitory factor (LIF/ESGRO ...
• RPRD Proteins Control Transcription in Human Cells

  Kinga Winczura, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and 1% Penicillin-Streptomycin (Merck, P0781).
• WNT6-ACC2-induced accumulation of triacylglycerol rich lipid droplets is exploited by M. tuberculosis

  Julius Brandenburg, et al., bioRxiv - Immunology 2020

  Quote: ... 1% penicillin/streptomycin (Merck, Darmstadt, Germany) and 10 ng/ml recombinant human M-CSF as described previously83 ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-ACE2 (Merck SAB3500346, 1:40), anti-CD147 (BioLegend #306221 ...
• GC content but not nucleosome positioning directly contributes to intron-splicing efficiency in Paramecium

  Stefano Gnan, et al., bioRxiv - Genomics 2021

  Quote: ... 1 mg/mL proteinase K (Merck) and incubated at 55°C overnight ...
• Dodecyl Creatine Ester Improves Cognitive Function and Identifies Drivers of Creatine Deficiency

  Aloïse Mabondzo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PSD95 (1:2000, Merck, MABN68), anti-tubulin (1:2000 ...
• Unraveling the intricate microtubule inner protein networks that reinforce mammalian sperm flagella

  Miguel Ricardo Leung, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1% benzonase (Merck Millipore, Darmstadt, Germany), 1 mM sodium orthovanadate ...
• Long-term mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

  Marco Novais-Cruz, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-Mad1 (1:1,000; Merck), rabbit anti-Kif4a (1:1,000 ...
• Long-term mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

  Marco Novais-Cruz, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-MPM2 (1:1,000, Merck), mouse anti-GAPDH (1:50,000 ...
• Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics

  Rahel Dabrowski, Susanna Tulli, Martin Graef, bioRxiv - Cell Biology 2022

  Quote: ... 1% (v/v) β-mercaptoethanol (Merck)).
• Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe

  Gaspard Kerner, et al., bioRxiv - Genetics 2022

  Quote: ... and 1 mM PMSF (#10837091001, Merck). Protein extracts and supernatants were resolved by electrophoresis in Criterion TGX 10% precast gels (Bio-Rad) ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Sox2 (1:150, Merck; Ab5603), anti-Iba1 (1:500 ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-NeuN (1:200, Merck; MAB377), anti-Ki67 (1:500 ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Sox2 (1:70, Merck; Ab5603), anti-MAP2 (1:100 ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-NeuN (1:150, Merck; MAB377) and ...
• Selective transduction and photoinhibition of pre-Botzinger neurons that project to the facial nucleus in rats affect the nasofacial activity

  MR Melo, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-TH (1:5000, Merck-Millipore ...
• SARM1 detection in oligodendrocytes but not Schwann cells though sarm1/Sarm1 deletion does not perturb CNS nor PNS myelination in zebrafish and mice

  Shaline V. Fazal, et al., bioRxiv - Neuroscience 2022

  Quote: ... Alexa Fluor 647 (Merck, 1:1000,15389818), DAPI (Thermo scientific ...
• Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia

  Md Rejaul Hoq, et al., bioRxiv - Neuroscience 2023

  Quote: ... RD3 (Merck 05–803, 1:3,000), and RD4 (Upstate ...
• Age-dependent NMDA receptor function is regulated by the Amyloid Precursor Protein

  Joana Rajão-Saraiva, et al., bioRxiv - Neuroscience 2022

  Quote: ... Synaptophysin (1:200, S5768, Merck Millipore), β-actin (1 :1000 ...
• Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells

  Yogesh Kumar, et al., bioRxiv - Genomics 2022

  Quote: ... 1% of nucleoside mix (Merck Millipore), 1000 U/ml recombinant leukemia inhibitory factor (LIF/ESGRO ...
• Slow integrin-dependent migration organizes networks of tissue-resident mast cells

  Sarah K. Bambach, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti- nidogen (1:300, Merck Millipore), anti-rat Alexa Fluor 405 (1:500 ...
• Silybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

  Solveigh C. Koeberle, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... [13C3]-Malonyl-CoA (1 nmol; Merck) was used as internal standard.
• Control of a gene transfer agent cluster in Caulobacter crescentus by transcriptional activation and anti-termination

  Ngat T. Tran, Tung B.K. Le, bioRxiv - Microbiology 2023

  Quote: ... 1 μL of Benzonase nuclease (Merck), and an EDTA-free protease inhibitor tablet (Merck) ...
• JNK1 And Downstream Signalling Hubs Regulate Anxiety-Like Behaviours In A Zebrafish Larvae Phenotypic Screen

  Ye Hong, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... Bryostatin-1 and MK801 from MERCK Sigma Aldrich Solutions ...
• Implementation of pupylation-based proximity labelling in plant biology reveals regulatory factors in cellulose biosynthesis

  Shuai Zheng, et al., bioRxiv - Plant Biology 2024

  Quote: ... α-YFP (Venus) (Merck, MABE1906, 1:1000) and secondary antibodies α-mouse-HRP (Agilent ...
• The eIF4A2 negative regulator of mRNA translation promotes extracellular matrix deposition to accelerate hepatocellular carcinoma initiation

  Madeleine Moore, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and ITGA5 (Merck AB1928, 1:1000). Fibronectin (abcam 2413 ...