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401 - 450 of 1325 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells

  Anoeska Agatha Alida van de Moosdijk, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Secondary antibodies were IRDye 680LT anti-mouse (1:20000, LI-COR) and IRDye 800CW anti-rabbit (1:20000 ...
• Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes

  João Pedro Fonseca, et al., bioRxiv - Systems Biology 2020

  Quote: ... IRDye 800CW Donkey anti-Rabbit (LI-COR #925-32213, 1:10000), IRDye 680RD Donkey antiMouse (LI-COR #925-68072 ...
• Hypercapnia Suppresses Macrophage Antiviral Activity and Increases Mortality of Influenza A Infection via Akt1

  S. Marina Casalino-Matsuda, et al., bioRxiv - Immunology 2020

  Quote: ... Signals were detected following incubation with IRDye (1:10,000, LI-COR) Biosciences or HRP-conjugated (1:5000 ...
• Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

  Odessa R. Yabut, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and secondary antibodies (1:5000 dilution; IR-Dye antibodies, LI-COR) for 1 hour at RT ...
• Protein S-nitrosylation of Human Cytomegalovirus pp71 inhibits its ability to limit STING antiviral responses

  Masatoshi Nukui, et al., bioRxiv - Microbiology 2020

  Quote: ... or IR-Dye 680RD anti-mouse antibody (1:15000, LI-COR). Membranes were then washed with 1X tris-buffered saline (TBS) ...
• Identification of a chemical probe for lipid kinase phosphatidylinositol-5-phosphate 4-kinase gamma (PI5P4Kγ)

  David H. Drewry, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:10,000 goat anti-mouse IRDYE 800CW (LI-COR, 926-32210); and 1:5000 goat anti-rabbit IgG HRP (Thermo ...
• Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein

  Austin Stoner, et al., bioRxiv - Neuroscience 2023

  Quote: ... Anti-Mouse IRDye 800CW (LI-COR Biosciences #926–32,212, 1:8000) and α-rabbit IRDye 680CW (LI-COR Biosciences ...
• Manganese-dependent microRNA trimming by 3’→5’ exonucleases generates 14-nucleotide or shorter tiny RNAs

  GeunYoung Sim, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and secondary antibodies: anti-mouse or rabbit (1:15,000, LI-COR). The protein bands were visualized by Odyssey.
• Mapping PTBP splicing in human brain identifies targets for therapeutic splice switching including SYNGAP1

  Jennine M. Dawicki-McKenna, et al., bioRxiv - Molecular Biology 2022

  Quote: ... IRDye 680RD anti-rabbit (LI-COR #926-68073, 1:10,000 dilution) and IRDye 800CW anti-mouse (LI-COR #926-32212 ...
• Calpain-mediated proteolysis of vimentin filaments is augmented in Giant Axonal Neuropathy (GAN) fibroblasts exposed to hypotonic stress

  Cassandra L. Phillips, et al., bioRxiv - Cell Biology 2022

  Quote: ... IRDye 680RD donkey anti-mouse IgG (LI-COR, WB 1:5000), and Alexa 488- and Alexa 568-conjugated goat anti-mouse and anti-rabbit antibodies (Invitrogen ...
• The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

  Hazel Stewart, et al., bioRxiv - Microbiology 2022

  Quote: ... and anti-goat IgG (1:10,000, donkey, LI-COR, 926-68074).
• Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing

  Maxwell Campbell, et al., bioRxiv - Microbiology 2024

  Quote: ... at 1:10,000 dilution and an Odyssey Scanning system (LI-COR).
• Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing

  Maxwell Campbell, et al., bioRxiv - Microbiology 2024

  Quote: ... at 1:10,000 dilution and an Odyssey Scanning system (LI-COR). As ClpP levels remain constant in Caulobacter ...
• Absolute calibration of ribosome profiling assesses the dynamics of ribosomal flux on transcripts

  Kotaro Tomuro, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and anti-β-actin (LI-COR Biosciences, #926-42212; 1:1000). For the secondary antibodies ...
• DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks

  Anja Göder, et al., bioRxiv - Biochemistry 2023

  Quote: ... 800CW goat anti-rabbit (926-32211; LI-COR Biosciences; 1:10,000) and 800CW goat anti-mouse (926-32210 ...
• Biomimetic fractal topography enhances podocyte maturation in vitro

  Chuan Liu, et al., bioRxiv - Bioengineering 2024

  Quote: ... appropriate IRDye800CW secondary antibodies were added (LI-COR, 1:10,000 concentration) for 2 hours ...
• Pharmacological characterization of the endocannabinoid sensor GRAB_eCB2.0

  Simar Singh, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... IRDye 800 CW conjugates donkey anti-goat (1:10,000; LI-COR).
• KAT6A mutations drive transcriptional dysregulation of cell cycle and Autism risk genes in an Arboleda-Tham Syndrome cerebral organoid model

  Aileen A. Nava, et al., bioRxiv - Genetics 2023

  Quote: ... goat anti-rabbit-IR-800 (LI-COR #92632211 at 1/5000), and anti-Tubulin-rhodamine (Biorad #12004165 at 1/1000) ...
• Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

  Allen L. Pan, et al., bioRxiv - Neuroscience 2023

  Quote: ... and goat anti-mouse 680LT (1:20,000, LI-COR, Lincoln, NE) in Odyssey blocking buffer with 0.1% Tween-20 and 0.01% SDS at room temperature for 1 hr ...
• Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

  Yevgeniy V. Serebrenik, et al., bioRxiv - Cell Biology 2023

  Quote: ... IRDye 800CW Goat anti-Mouse (LI-COR 926-32210, 1:10,000).
• Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

  Yevgeniy V. Serebrenik, et al., bioRxiv - Cell Biology 2023

  Quote: ... IRDye 680LT Goat anti-Rabbit (LI-COR 926-68021, 1:10,000), IRDye 800CW Goat anti-Mouse (LI-COR 926-32210 ...
• Hem25p is a mitochondrial IPP transporter

  Jonathan Tai, et al., bioRxiv - Biochemistry 2023

  Quote: ... IRDye 680RD goat anti-mouse (LI-COR 926-68070, 1:15000), IRDye 800CW (LI-COR 926-32210 ...
• Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A

  Stefan Harjes, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and goat anti-mouse IRdye680 (LI-COR, #926-69020, 1:10000). Raw immunoblots are included in Supplementary Information ...
• FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation, and lethality in glioblastoma and other cancers

  Pia Hoellerbauer, et al., bioRxiv - Cancer Biology 2022

  Quote: ... The following secondary antibodies were used (LI-COR, all 1:10,000): #926-68073 ...
• The class XIV myosin of Toxoplasma gondii, TgMyoA, is druggable in an animal model of infection

  Anne Kelsen, et al., bioRxiv - Microbiology 2023

  Quote: ... Goat anti-rabbit IRDye800CW (1:20,000; LI-COR Biosciences, Lincoln, NE) was used as a secondary antibody ...
• RSV infection does not induce EMT

  Sattya N. Talukdar, et al., bioRxiv - Microbiology 2023

  Quote: ... and goat anti-rabbit IRDye800 Ab (1:15000) (LI-COR Biosciences) for 1 hour ...
• Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion–FAK axis

  Taisei Wakigawa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... IRDye800CW anti-rabbit IgG (LI-COR Biosciences, 926-32211, 1:10000) was used as a secondary antibody ...
• Development of a cellular reporter assay to measure activity of MutSβ, a therapeutic target for Huntington’s disease

  Jian An, et al., bioRxiv - Neuroscience 2023

  Quote: ... Membranes were blocked for 1 hour at room temperature (LI-COR Intercept TBS blocking buffer ...
• Mapping RNA-Protein Interactions with Subcellular Resolution Using Colocalization CLIP

  Soon Yi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... membranes were incubated with fluorescent secondary antibodies (LI-COR, 1:25,000) for 1 hr at room temperature ...
• Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

  Stephanie E. Sansbury, et al., bioRxiv - Cell Biology 2023

  Quote: ... IRDye 680LT Goat anti-Rabbit (LI-COR 926-68021, 1:10,000), IRDye 800CW Goat anti-Mouse (LI-COR 926-32210 ...
• Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

  Stephanie E. Sansbury, et al., bioRxiv - Cell Biology 2023

  Quote: ... IRDye 800CW Goat anti-Mouse (LI-COR 926-32210, 1:10,000).
• Retinoid X Receptor as a Novel Drug Target to Treat Neurological Disorders Associated with α- Synucleinopathies

  Assylbek Zhylkibayev, et al., bioRxiv - Neuroscience 2024

  Quote: ... Secondary antibodies (1:10000 for all) were purchased from LI-COR: HRP goat anti-Rabbit IgG (926-80011 ...
• PARP14 mediated SQSTM1/p62 cysteine ADP-ribosylation is counteracted by the SARS-CoV-2 macrodomain

  David Kubon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... IRDye 800 CW goat anti-rabbit IgG (LI-COR, 1:10000) and IRDye 680RD goat anti-mouse IgG (LI-COR ...
• PARP14 mediated SQSTM1/p62 cysteine ADP-ribosylation is counteracted by the SARS-CoV-2 macrodomain

  David Kubon, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and IRDye 680RD goat anti-mouse IgG (LI-COR, 1:10000).
• Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons

  Chun Hei Li, et al., bioRxiv - Cell Biology 2024

  Quote: ... IRDye 800CW Streptavidin (LI-COR Biosciences, Cat#926-32230, 1/10000), antibody labeling kit Mix-n-Stain CF640R (Biotium) ...
• Novel Endogenous Engineering Platform for Robust Loading and Delivery of Functional mRNA by Extracellular Vesicles

  Antje M. Zickler, et al., bioRxiv - Bioengineering 2024

  Quote: ... and dy-α-gt IRDye680RD (1:10000) (all LI-COR Biosciences).
• Generation of humanized mouse models to support therapeutic development for SYNGAP1 and STXBP1 disorders

  Alex J. Felix, et al., bioRxiv - Neuroscience 2024

  Quote: ... IRDye 680RD anti-rabbit (LI-COR #926-68073, 1:10,000 dilution) and IRDye 800CW anti-mouse (LI-COR #926-32212 ...
• Gigaxonin, mutated in Giant Axonal Neuropathy, interacts with TDP-43 and other RNA binding proteins

  Cassandra L. Phillips, et al., bioRxiv - Cell Biology 2024

  Quote: ... IRDye 680RD donkey anti-mouse IgG (LI-COR, WB 1:5000), and Alexa 488 ...
• PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis

  Thomas H. Sisson, et al., bioRxiv - Pathology 2024

  Quote: ... or goat anti-mouse-700 (1:20000, LI-COR 926-68070), washed 3-times with TBS 0.1% Tween-20 ...
• Mechanistic studies of PFKFB2 reveals a novel inhibitor of its kinase activity

  Craig Eyster, et al., bioRxiv - Biochemistry 2024

  Quote: ... blocked for 1 hr with Odyssey TBS blocking buffer (LI-COR). Antibodies used were ...
• Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA

  Lulu Yin, et al., bioRxiv - Biochemistry 2024

  Quote: ... and goat anti-mouse IRdye680 (LI-COR, #926-69020, 1:10,000).
• Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio

  Katherine R. Ferrick, et al., bioRxiv - Cell Biology 2024

  Quote: ... RRID: AB_330924) or fluorophore-conjugated secondary antibodies (1:10,000, LI-COR Biosciences ...
• CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation

  Gregory Cajka, Matthew Liu, Ophir Shalem, bioRxiv - Cell Biology 2024

  Quote: ... IRDye 800CW Goat anti-Mouse (LI-COR, 926-32210; 1:10,000).
• The histone demethylase KDM5 has insulator activity in the brain

  Matanel Yheskel, et al., bioRxiv - Genetics 2024

  Quote: ... and IRDye 800CW donkey anti-rabbit IgG (1:5000; LI-COR Biosciences cat# 926-32213 ...
• Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia

  Luca J. Delfinis, et al., bioRxiv - Physiology 2024

  Quote: ... membranes were washed 3 times for 5 minutes in TBS-Tween and incubated for 1 hour at room temperature with the corresponding infrared fluorescent secondary antibody (LI-COR IRDye 680RD 925-68020, 1:20 000).
• Widespread reorganisation of the regulatory chromatin landscape facilitates resistance to inhibition of oncogenic ERBB2 signalling

  Samuel Ogden, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Secondary antibodies used: anti-rabbit (LI-COR Biosciences, 926-32213, 1:10,000) and anti-mouse (LI-COR Biosciences ...
• NMNAT promotes glioma growth through regulating post-translational modifications of p53 to inhibit apoptosis

  Jiaqi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or near-infrared (IR) dye 700/800 (1:5000, LI-COR Biosciences). HRP-anti-Mouse and HRP-anti-Rabbit (1:5000 ...
• A septin GTPase scaffold of dynein-dynactin motors triggers retrograde lysosome transport

  Ilona A. Kesisova, et al., bioRxiv - Cell Biology 2020

  Quote: ... Secondary antibodies for Western blots (1:10,000) were purchased from LI-COR including donkey anti-mouse and anti-rabbit 800CW or 680RD conjugates ...
• UFMylation regulates translational homeostasis and cell cycle progression

  Igor A. Gak, et al., bioRxiv - Cell Biology 2020

  Quote: ... IRDye® 680RD Donkey anti-Mouse (LI-COR, 926-68072, 1:20000), IRDye® 800CV Donkey anti-Mouse (LI-COR ...
• UFMylation regulates translational homeostasis and cell cycle progression

  Igor A. Gak, et al., bioRxiv - Cell Biology 2020

  Quote: ... IRDye® 800CV Donkey anti-Mouse (LI-COR, 926-32212, 1:20000) and IRDye® 800CV Donkey anti-Rabbit (LI-COR ...