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601 - 650 of 1325 citations for 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide since 2020

• Cloning and functional characterization of novel human neutralizing anti-interferon-alpha and anti-interferon-beta antibodies

  Emmanouil Papasavvas, et al., bioRxiv - Immunology 2024

  Quote: ... membranes were treated with cloned Ab supernatant (1:200) in OBB (LI-COR) containing 0.1% Tween 20 (Sigma-Aldrich ...
• Cytosolic S100A8/A9 promotes Ca²⁺ supply at LFA-1 adhesion clusters during neutrophil recruitment

  Matteo Napoli, et al., bioRxiv - Physiology 2024

  Quote: ... and goat-α-rabbit IRDye800CW-coupled secondary antibodies (1μg mL-1, LI-COR).
• Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Promote Establishment and Maintenance of the Legionella Replication Vacuole

  Kristin M. Kotewicz, et al., bioRxiv - Microbiology 2024

  Quote: ... goat IRDye 800CW α-rabbit (LI-COR Biosciences, Cat# 926-32211, 1:20,000) for 45 min at room temperature ...
• Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Promote Establishment and Maintenance of the Legionella Replication Vacuole

  Kristin M. Kotewicz, et al., bioRxiv - Microbiology 2024

  Quote: ... Goat IRDye 680RD anti-rabbit (LI-COR Biosciences, Cat# 926-68071, 1:20,000), and/or donkey IRDye800CW anti-mouse (LI-COR Biosciences ...
• Spinal cord phosphoproteome of a SCA2/ALS13 mouse model reveals alteration of ATXN2-N-term SH3-actin interactome and of autophagy via WNK1-MYO6-OPTN-SQSTM1

  Luis-Enrique Almaguer-Mederos, et al., bioRxiv - Molecular Biology 2024

  Quote: ... or IRDye® 680RD goat anti-rabbit (LI-COR 926-68071, 1:10,000). Membranes were scanned using an Odyssey® Classic Imager ...
• Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles

  Nilanjana Saferin, et al., bioRxiv - Neuroscience 2024

  Quote: ... and IRDye 800CW Donkey anti-Mouse (926-32212, 1:10,000 dilution, LI-COR).
• Lysosomes cell autonomously regulate myeloid cell states and immune responses

  Leon Tejwani, et al., bioRxiv - Neuroscience 2024

  Quote: ... IRDye 800CW goat anti-rabbit IgG (LI-COR; Cat# 926-32211; 1:15000), and rabbit anti-sheep IgG DyLight800 (Invitrogen ...
• Lysosomes cell autonomously regulate myeloid cell states and immune responses

  Leon Tejwani, et al., bioRxiv - Neuroscience 2024

  Quote: ... IRDye 800CW goat anti- mouse IgG (LI-COR; Cat# 926-32210; 1:15000), IRDye 800CW goat anti-rabbit IgG (LI-COR ...
• Lysosomes cell autonomously regulate myeloid cell states and immune responses

  Leon Tejwani, et al., bioRxiv - Neuroscience 2024

  Quote: ... IRDye 680RD goat anti-rabbit IgG (LI-COR; Cat# 926-68071; 1:15000), IRDye 800CW goat anti- mouse IgG (LI-COR ...
• Chromosomal instability promotes cell migration and invasion via EFEMP1 secretion into extracellular vesicles

  Siqi Zheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and IRDye 680CW Goat anti-Mouse IgG (H+L) (1:15000, LI-COR), or for HRP-conjugated antibodies ...
• Reprograming gene expression in hibernating C. elegans involves the IRE-1/XBP-1 pathway

  Melanie L. Engelfriet, et al., bioRxiv - Cell Biology 2024

  Quote: ... blocked for 1 hour in Intercept (TBS) Blocking Buffer (LI-COR, 927-60001), and incubated overnight at 4°C with primary antibodies diluted in the same blocking buffer ...
• Enhancement of response learning in male rats with intrastriatal infusions of a BDNF - TrkB agonist, 7,8-dihydroxyflavone

  Robert S. Gardner, et al., bioRxiv - Neuroscience 2024

  Quote: ... membranes were reblocked for 1 hr in TBS Odyssey blocking buffer (LI-COR) and incubated with anti-β-tubulin mouse monoclonal antibody (1:30,000 ...
• Enhancement of response learning in male rats with intrastriatal infusions of a BDNF - TrkB agonist, 7,8-dihydroxyflavone

  Robert S. Gardner, et al., bioRxiv - Neuroscience 2024

  Quote: Membranes were blocked for 1 hr in TBS Odyssey blocking buffer (LI-COR) and incubated with anti-phospho-TrkB Y816 rabbit polyclonal (1:1000 ...
• An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation

  Gareth Moore, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and IRDye 800CW donkey anti-Mouse IgG (1:10,000, LI-COR, RRID: AB_621847) secondary antibodies ...
• APOBEC3 mutagenesis drives therapy resistance in breast cancer

  Avantika Gupta, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Rabbit IgG IRDye 680 RD (1:10000, LI-COR Biosciences 926-68071), and anti-Mouse IgG IRDye 800 RD (1:10000 ...
• A novel and robust method for assessing mitochondrial (dys)function in healthy and diseased frozen cardiac tissue

  Liangyu Hu, et al., bioRxiv - Physiology 2024

  Quote: ... or IRDye 680RD Donkey anti-rabbit (926-68073, LI-COR, 1:5000 dilution), respectively ...
• A novel and robust method for assessing mitochondrial (dys)function in healthy and diseased frozen cardiac tissue

  Liangyu Hu, et al., bioRxiv - Physiology 2024

  Quote: ... or IRDye 680RD Donkey anti-rabbit (926-68073, LI-COR, 1:5000 dilution) for 1 h at room temperature and visualized using an Odyssey scanner (LI-COR).
• Sense codon-misassociated eRF1 elicits widespread ribosome stalling and induction of quality control

  Peixun Han, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and IRDye 800CW anti-mouse IgG (LI-COR Biosciences, #926-32210, 1:10000). The membranes were imaged via an ODYSSEY CLx system (LI-COR Biosciences).
• Modelling oxaliplatin resistance in colorectal cancer reveals a SERPINE1-based gene signature (RESIST-M) and therapeutic strategies for pro-metastatic CMS4 subtype

  Stephen Qi Rong Wong, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and blocked for 1 hour with TBS blocking buffer (927-60001, LI-COR) or 1.5% non-fat milk (#1706404 ...
• Neurons and astrocytes have distinct organelle signatures and responses to stress

  Shannon N. Rhoads, et al., bioRxiv - Cell Biology 2024

  Quote: ... primary and 1:10,000 goat anti-chicken IRDye 800CW (LI-COR 926- 32211) secondary antibodies.
• TGF-β induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis

  Zhenghan Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... IRDye 680RD goat anti-rat (LI-COR Biosciences, Cat# 926-68076, 1:10000) or IRDye 800CW goat anti-rabbit (LI-COR Biosciences ...
• Methylglyoxal induces nuclear accumulation of p53 and γH2AX in normal and cancer cells

  Astrid Veß, Thomas Hollemann, bioRxiv - Cell Biology 2020

  Quote: ... Fluorophore-labeled secondary antibodies used at 1:10.000 dilutions (LI-COR, Bad Homburg, Germany) were incubated for 1 h at room temperature ...
• Species-specific deployment of Runx2 isoforms and differential regulation of target genes during avian jaw development and evolution

  Spenser S. Smith, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1:15000 goat anti-rabbit IRDye 800CW (925-32211, LI-COR, Lincoln, NE, USA), and 1:15000 donkey anti-mouse IRDye 680RD antibody (925-68072 ...
• Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution

  Spenser S. Smith, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1:15000 goat anti-rabbit IRDye 800CW (925-32211, LI-COR, Lincoln, NE, USA), and 1:15000 donkey anti-mouse IRDye 680RD antibody (925-68072 ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... IRDye-labelled secondary anti-Mouse IgG-IRDye 800CW (LI-COR; 925-32210; 1:5000) and anti-Rabbit IgG-IRDye® 680RD (LI-COR ...
• Distinct silencer states determine epigenetic states of heterochromatin

  Daniel S. Saxton, Jasper Rine, bioRxiv - Cell Biology 2022

  Quote: ... Secondary antibodies used were goat anti-rabbit CW680 (LI-COR #C81106-03, 1:20,000) and goat anti-mouse CW800 (LI-COR #C60531-05 ...
• A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1

  Jose M. González de Cózar, et al., bioRxiv - Molecular Biology 2020

  Quote: ... used with either IRDve® 680LT anti-mouse (LI-COR, 925-68022, 1:10,000) or IRDve® 680LT anti-rabbit (LI-COR ...
• Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages

  Eric Yau, et al., bioRxiv - Immunology 2021

  Quote: ... and IRDye 800 CW anti-Rabbit IgG (LI-COR Cat#926-32211, 1:10000). Blots were imaged using LI-COR Odyssey CLx and Image Studio 4.0 ...
• Loss of SUV420H2 promotes EGFR inhibitor resistance in NSCLC through upregulation of MET via LINC01510

  A.S. Pal, et al., bioRxiv - Cancer Biology 2020

  Quote: ... The primary antibody was detected using 1:800 IR 800CW secondary antibody (LI-COR). The IR-800 signal was quantified using the Odyssey LI-COR imaging system and software ...
• Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

  Yuexia Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cells were then incubated for 1 hr with IRDye680RD goat anti-mouse (LI-COR) and Alexa Fluor 647 donkey anti-rat (Abcam ...
• Efficient flavinylation of glycosomal fumarate reductase by its own ApbE domain in Trypanosoma brucei

  Robin Schenk, et al., bioRxiv - Biochemistry 2020

  Quote: ... and goat IRDye 680LT α-rabbit IgG (H + L) (1:5000; LI-COR Biosience) were used as secondary antibodies ...
• mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes

  Brendan Rooney, et al., bioRxiv - Cell Biology 2021

  Quote: ... and goat anti-rabbit IRDye 680RD (1:10,000; LI-COR cat. no. 926-68071) in blocking buffer (see above ...
• The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission

  Yunkai Zhu, et al., bioRxiv - Microbiology 2020

  Quote: ... or goat anti-mouse IRDye 800CW secondary antibody (LI-COR #926-32210, 1:10000), then developed and analyzed with the Odyssey CLx Imaging System.
• UbiB proteins regulate cellular CoQ distribution

  Zachary A. Kemmerer, et al., bioRxiv - Cell Biology 2020

  Quote: ... Secondary antibodies include goat anti-mouse (LI-COR 926-32210, 1:15000; RRID: AB_621842) and goat anti-rabbit (LI-COR 926-32211 ...
• Quantitative live-cell imaging and computational modelling yield novel insight into endogenous WNT/CTNNB1 signaling dynamics

  S.M.A. de Man, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:20.000 IRDye 680LT Goat anti-Rabbit IgG (926-68021, LI-COR, Lincoln, NE), 1:20.000 IRDye 800CW Donkey anti-Mouse IgG (926–32212 ...
• Visualizing Molecules of Functional Human Profilin

  Morgan L. Pimm, et al., bioRxiv - Cell Biology 2022

  Quote: ... and probed with goat anti-mouse:IRDye 800CW (1:5,000; LI-COR Biosciences 926-32210), and donkey anti-rabbit 926-68073 (1:20,000 ...
• Disruption of the MICOS complex leads to an aberrant cristae structure and an unexpected, pronounced lifespan extension in Podospora anserina

  Verena Warnsmann, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 926-32211) and IRDye® 680RD anti-mouse (goat, dilution 1:15000, LI-COR Biosciences ...
• Human sialomucin CD164 is an essential entry factor for lymphocytic choriomeningitis virus

  Jamin Liu, et al., bioRxiv - Microbiology 2022

  Quote: ... for 1 h at room temperature and visualized using the Odyssey CLx (LI-COR). Antibody details can be found in Table S3.
• An automated high-content synaptic phenotyping platform in human neurons and astrocytes reveals a role for BET proteins in synapse assembly

  Martin H. Berryer, et al., bioRxiv - Neuroscience 2022

  Quote: ... For visualization Donkey anti-Mouse IRDye® 800CW (1:5000, LI-COR, 926-32212) and Donkey anti-Rabbit IRDye® 680RD (1:5000 ...
• Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

  Hudson W. Coates, et al., bioRxiv - Molecular Biology 2022

  Quote: ... IRDye 680RD donkey anti-rabbit IgG (LI-COR Biosciences LCR-926-68073; 1:5,000), IRDye 800CW donkey anti-mouse IgG (LI-COR Biosciences LCR-926-32212 ...
• Stepwise maturation of the peptidyl transferase region of human mitoribosomes

  Tea Lenarčič, et al., bioRxiv - Biochemistry 2021

  Quote: ... All primary antibodies were diluted 1:1000 using the Odyssey blocking buffer (LI-COR). IR Dye 800CW Goat Anti-Rabbit IgG or IR Dye 680LT Goat Anti-Mouse IgG (LI-COR ...
• Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33

  Michael A. Schumacher, et al., bioRxiv - Physiology 2020

  Quote: ... for 1 hour at room temperature and quantification on an Odyssey imager (LI-COR).
• E2F4 as a single multifactorial target against Alzheimer’s disease

  Noelia López-Sánchez, et al., bioRxiv - Pathology 2021

  Quote: ... The membranes were incubated for 1 h with Intercept Blocking Buffer TBS (LI-COR) (IBB) ...
• E2F4 as a single multifactorial target against Alzheimer’s disease

  Noelia López-Sánchez, et al., bioRxiv - Pathology 2021

  Quote: ... The membranes were incubated for 1 h with Odyssey Blocking Buffer TBS (LI-COR) (OBB) ...
• Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria parasites

  Philip M Frasse, et al., bioRxiv - Microbiology 2021

  Quote: ... then probed with secondary antibodies goat anti rabbit IRDye 800CW 1:20,000 (LI-COR) and donkey anti-mouse IRDye 680LT 1:20,000 (LI-COR) ...
• MTHFD2 is a Metabolic Checkpoint Controlling Effector and Regulatory T Cell Fate and Function

  Ayaka Sugiura, et al., bioRxiv - Immunology 2021

  Quote: ... Blots were blocked for 1 hour using Intercept (TBS) Blocking Buffer (LI-COR Biosciences), before incubation with primary antibody overnight at 4°C.
• Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia

  Alaullah Sheikh, et al., bioRxiv - Microbiology 2022

  Quote: ... and anti-mouse IR-680 dye (1:30,000; Cat# 926-68020; LI-COR Bioscience) secondary antibodies incubation for 1 h at room temperature ...
• Silybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

  Solveigh C. Koeberle, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... IRDye 800CW-labeled anti-rabbit IgG (1:10,000, 92632211, LI-COR Biosciences, Lincoln, NE), IRDye 800CW-labeled anti-mouse IgG (1:10,000 ...
• EDC-3 and EDC-4 Regulate Embryonic mRNA Clearance and Biomolecular Condensate Specialization

  Elva Vidya, et al., bioRxiv - Molecular Biology 2024

  Quote: Secondary antibodies used were: IRDye 800CW Goat anti-Rabbit (1:10 000) (LI-COR), IRDye 680RD Goat anti-Mouse (1 ...
• RNA dicing regulates the expression of an oncogenic JAK1 isoform

  Yuval Malka, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and IRDye® 680RD Goat anti-Mouse IgG (LI-COR, 926-68070, 1:10000).