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4101 - 4150 of 10000+ citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• Leptospiral LPS escapes mouse TLR4 internalization and TRIF-associated antimicrobial responses through O antigen and associated lipoproteins

  Delphine Bonhomme, et al., bioRxiv - Immunology 2020

  Quote: ... ELISA DuoSet kits (R&D Systems) were used according to the manufacturer’s instructions ...
• Epitranscriptomic reprogramming is required to prevent stress and damage from acetaminophen

  Sara Evke, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Gpx3 (Catalog #AF4199, R&D Systems), Gpx4 (catalog no ...
• Role of Inflammasome-independent Activation of IL-1β by the Pseudomonas aeruginosa Protease LasB

  Josh Sun, et al., bioRxiv - Microbiology 2020

  Quote: ... and IETD-fmk (R&D Systems), 10 µg/mL complete protease inhibitor cocktail (Roche) ...
• Cofilin Regulates Filopodial Structure and Flexibility in Neuronal Growth Cones

  Ryan Hylton, et al., bioRxiv - Cell Biology 2021

  Quote: ... with 10% FBS (R&D Systems) and 1% Penicillin-Streptomycin (Gibco) ...
• Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

  Sajina Shakya, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 10ng/mL bFGF (R&D Systems), B27 (Invitrogen ...
• STEM CELL TECHNOLOGY PROVIDES NOVEL TOOLS TO UNDERSTAND HUMAN VARIATION IN Plasmodium falciparum MALARIA

  Alena Pance, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10ng/ml FLT3 (R&D Systems).
• eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

  Takeshi Ninchoji, et al., bioRxiv - Cell Biology 2020

  Quote: ... Recombinant mouse VEGFA164 (R&D Systems), was used at 50 ng/ml for in vitro analyses ...
• The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation

  Nicholas W. Chavkin, et al., bioRxiv - Cell Biology 2021

  Quote: ... Ror2 (R&D Systems Cat #AF2064).
• Lysosomal Exocytosis Releases Pathogenic α-Synuclein Species from Neurons

  Ying Xue Xie, et al., bioRxiv - Cell Biology 2021

  Quote: ... or N21-MAX (R&D Systems), and neurons were infected at the same time with lentiviruses ...
• Heterogenous impairment of α-cell function in type 2 diabetes is linked to cell maturation state

  Xiao-Qing Dai, et al., bioRxiv - Cell Biology 2021

  Quote: ... ARX (R&D Systems, cat#AF7068) and GCG (Sigma ...
• A cancer cell-intrinsic GOT2-PPARδ axis suppresses antitumor immunity

  Hannah Sanford-Crane, et al., bioRxiv - Cancer Biology 2020

  Quote: ... His (R&D Systems MAB050-100), COX2 (Abcam ab15191) ...
• A cancer cell-intrinsic GOT2-PPARδ axis suppresses antitumor immunity

  Hannah Sanford-Crane, et al., bioRxiv - Cancer Biology 2020

  Quote: ... His (R&D Systems MAB050-100). Coverslips were incubated with the primary antibody at 4°C overnight and then washed five times for 5 minutes each in PBS following which ...
• Clearing of ribosome collisions by the ribosome quality control trigger complex RQT

  Katharina Best, et al., bioRxiv - Biochemistry 2022

  Quote: ... 116 nM UBE1 (R&D systems), 3.3 µM Ubc4 and 757 nM Hel2 in a reaction buffer (20 mM HEPES-KOH pH 7.4 ...
• Extracellular Vesicle Antibody Microarray for Multiplexed Inner and Outer Protein Analysis

  Rosalie Martel, et al., bioRxiv - Bioengineering 2022

  Quote: ... ITG α6 (MAB1350, R&D Systems)-BC09 and Alix (MA1-83977 ...
• Sorting single T cells based on secreted cytokines and surface markers using hydrogel nanovials

  Doyeon Koo, et al., bioRxiv - Bioengineering 2022

  Quote: ... anti-TNF-α (R&D Systems), or anti-IL-2 (BD Sciences) ...
• EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance

  Loretah Chibaya, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and NKp46 (AF1850, R&D Systems). EZH2 staining was scored as high (strong nuclear staining throughout tumor) ...
• Variable Shh and Fgf8 positioning in regenerating axolotl limb guarantees consistent limb morphogenesis in different limb sizes

  Saya Furukawa, et al., bioRxiv - Developmental Biology 2022

  Quote: ... FGF8 (R&D systems, #423-F8) or/and SHH (R&D systems ...
• IL-33 regulates age-dependency of long-term immune dysfunction induced by sepsis

  David F. Colon, et al., bioRxiv - Immunology 2022

  Quote: ... using antibodies from R&D Systems according to the manufacturer’s instructions ...
• Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response

  Johanna L. Mehl, et al., bioRxiv - Cell Biology 2022

  Quote: ... For Fludarabine (3495 R&D Systems) treatment ...
• PKD-1 Signaling Is Required for the Maintenance of CSCs with Epithelial-mesenchymal Plasticity in Pancreatic Neuroendocrine Tumors

  Yichen Guo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and ALDH1A1 (AF5869) (R&D Systems). Antibodies for immunostaining included rabbit anti-human/mouse PKD-1 (SAB4502371 ...
• Reducing Cholesterol in Macrophage Activates NF-kB through Mitochondria, Resulting in Epigenomic Reprogramming to Dampen Inflammation

  Zeina Salloum, et al., bioRxiv - Cell Biology 2022

  Quote: ... were purchased from TOCRIS chemicals (part of R&D systems). Methyl-β-cyclodextrin (MCD) ...
• A novel PNGase Rc for improved protein N-deglycosylation in bioanalytics and HDX-MS epitope mapping under challenging conditions

  Marius Gramlich, et al., bioRxiv - Biochemistry 2022

  Quote: ... meningosepticum (R&D Systems, Wiesbaden, Germany), human SIRPα (Glu 31 - Arg 370 (ACROBiosystems ...
• EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance

  Loretah Chibaya, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and NKp46 (AF2225, R&D Systems). HRP-conjugated secondary antibodies (Vectastain Elite ABC Kits ...
• IKK2/NFkB signaling controls lung resident CD8 T cell memory during influenza infection

  Curtis J. Pritzl, et al., bioRxiv - Immunology 2022

  Quote: ... TGFβ (R&D Systems, Minneapolis, MN) was then added to a final concentration of 50 ng/ml ...
• Stress-Mediated Attenuation of Translation Undermines T Cell Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2022

  Quote: ... Proteasome Activity Probe (R&D Systems) was stained on cells of interest at 2.5μM for 2 hours at 37 C in PBS ...
• Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine

  Alexandra Atalis, et al., bioRxiv - Immunology 2022

  Quote: ... DuoSet ELISA kits (R&D Systems) were used to quantify IFN-β and IFN-λ3 from BMDC supernatants ...
• Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation

  Jack A. Bibby, et al., bioRxiv - Immunology 2022

  Quote: ... DEFA1 (R&D Systems, 2µg/ml), anti-sheep IgG-NL557 (R&D Systems ...
• Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

  Francesco Limone, et al., bioRxiv - Neuroscience 2022

  Quote: ... CNTF and GDNF (R&D Systems). For seeding and culturing the first 2 days ...
• Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

  Francesco Limone, et al., bioRxiv - Neuroscience 2022

  Quote: ... CNTF and GDNF (R&D Systems) and while medium in motor neuron compared contained no neurotrophic factors to start recruitment of motor neuron axons to the muscle compartment by generation of a volumetric gradient (50 μl difference in volume between the compartments ...
• Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

  Francesco Limone, et al., bioRxiv - Neuroscience 2022

  Quote: ... CNTF and GDNF (R&D Systems). For most experiments ...
• Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

  Francesco Limone, et al., bioRxiv - Neuroscience 2022

  Quote: ... CNTF and GDNF (R&D Systems). For day 7 to 10 ...
• Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

  Francesco Limone, et al., bioRxiv - Neuroscience 2022

  Quote: ... CNTF and GDNF (R&D Systems). On day 7 ...
• Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

  Francesco Limone, et al., bioRxiv - Neuroscience 2022

  Quote: ... CNTF and GDNF (R&D Systems). For most experiments ...
• Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

  Hyosung Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... recombinant mouse Serpina3n (R&D Systems), at a concentration of 50 or 100 ng/ml ...
• Heterogeneity of Inflammation-associated Synovial Fibroblasts in Rheumatoid Arthritis and Its Drivers

  Melanie H Smith, et al., bioRxiv - Immunology 2022

  Quote: Anti-CD90-AF700 (R&D systems; FAB2067N ...
• Chronic obstructive pulmonary disease and cigarette smoke exposure lead to dysregulated MAIT cell activation by bronchial epithelial cells

  Megan E. Huber, et al., bioRxiv - Immunology 2022

  Quote: ... α-IL-12p70 (MAB219100, R&D systems), α-IL-18 (D044-3 ...
• Soluble extracts from amnion and chorion membranes improve hMSC osteogenic response in a mineralized collagen scaffold

  Vasiliki Kolliopoulos, et al., bioRxiv - Bioengineering 2022

  Quote: ... An OPG ELISA (R&D Systems) was used with 100 μL of sample with PBS as a background control ...
• A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability

  Emily A. Voigt, et al., bioRxiv - Immunology 2022

  Quote: ... (R&D Systems, #10549-CV-100) at a concentration of 2 µg/mL diluted in ELISpot coating buffer (eBioScience) ...
• Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program

  Caitlan D. Byerly, et al., bioRxiv - Microbiology 2022

  Quote: ... rShh (R&D Systems, Minneapolis, MN) and rPTCH2 (MyBioSource ...
• A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced-neurons

  Elsa Papadimitriou, et al., bioRxiv - Neuroscience 2022

  Quote: ... 20ng/ml BDNF (R&D Systems), 0.5mM cAMP (Sigma ...
• Extracellular Vesicle Antibody Microarray for Multiplexed Inner and Outer Protein Analysis

  Rosalie Martel, et al., bioRxiv - Bioengineering 2022

  Quote: ... ITG β4 (MAB4060, R&D Systems)-BC79 ...
• Extracellular Vesicle Antibody Microarray for Multiplexed Inner and Outer Protein Analysis

  Rosalie Martel, et al., bioRxiv - Bioengineering 2022

  Quote: ... ITG α2 (MAB1233, R&D Systems)-BC64 and HSP70-BC23 ...
• Extracellular Vesicle Antibody Microarray for Multiplexed Inner and Outer Protein Analysis

  Rosalie Martel, et al., bioRxiv - Bioengineering 2022

  Quote: ... ITG β1 (MAB17781, R&D Systems)-BC27 ...
• Premature MeCP2 Expression Disturbs the Subtype Specification of Midbrain Dopamine Neurons

  Xi-Biao He, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-NURR1 (R&D Systems), mouse anti-TH (Sigma) ...
• ERK-mediated Curvature Feedback Regulates Branching Morphogenesis in Lung Epithelial Tissue

  Tsuyoshi Hirashima, Michiyuki Matsuda, bioRxiv - Developmental Biology 2022

  Quote: ... FGF1 (R&D Systems, #232-FA), and FGF7 (R&D Systems ...
• Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer

  Ashley Mello, et al., bioRxiv - Cancer Biology 2022

  Quote: ... IL6 (#DY406-05, R&D Systems), and LIF (#445104 ...
• SOX17 Is Not Required for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines

  Xudong Dong, Ailing Ding, Jiangwei Lin, bioRxiv - Developmental Biology 2022

  Quote: ... Primary antibodies from R&D Systems were against GATA6 (#AF1700) ...
• ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

  Asmi Chakraborty, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and anti-ST6GAL1 (R&D systems). Slides were incubated with the appropriate secondary antibody ...
• HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

  Jenny Horndahl, et al., bioRxiv - Cell Biology 2022

  Quote: For TGF-β1 (R&D Systems) experiments ...
• Claudin5 protects the peripheral endothelial barrier in an organ and vessel type-specific manner

  M Richards, et al., bioRxiv - Cell Biology 2022

  Quote: ... VE-Cadherin (R&D Systems, AF1002), JAM-A (Martin-Padura et al. ...