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3601 - 3650 of 10000+ citations for R + SCH 23390 hydrochloride since 2020

• The extracellular matrix differentially directs myoblast motility in distinct forms of muscular dystrophy

  Ashlee M. Long, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-TIMP-1 (cat# AF980; R&D Systems). Secondary antibodies used ...
• Selective Inhibition of Interleukin-2 Inducible T Cell Kinase (ITK) Enhances Anti-Tumor Immunity in Association with Th1-skewing, Cytotoxic T cell Activation, and Reduced T Cell Exhaustion

  Lih-Yun Hsu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and IL-12 (10 ng/ml, R&D Systems), anti-human IL-4 (OA19A66 ...
• CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predators

  Hao-Ching Jiang, et al., bioRxiv - Animal Behavior and Cognition 2023

  Quote: ... goat anti-NeuroD1 (1:50, R&D Systems, #AF2746), goat anti-OMP (1:1000 ...
• An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons

  Holly N. Cukier, et al., bioRxiv - Genetics 2023

  Quote: ... Human/Mouse/Rat SOX1 Antibody (R&D Systems, # AF3369), Purified anti-Tubulin β-3 (TUBB3 ...
• Spatial proteomics reveals heterogeneity in neural markers underpinning high-fat diet-induced myopathy in male mice

  Lydia Hardowar, et al., bioRxiv - Physiology 2023

  Quote: ... and CD31 (R&D systems, U.K, goat anti-PECAM1) and UV-cleavable oligo-labelled detection antibody panel (GeoMx Neural Cell Profiling Panel) ...
• Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-TrkA (R&D Systems, AF175, 1:500), goat anti-TrkB (R&D Systems ...
• APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

  Michael S. Haney, et al., bioRxiv - Neuroscience 2023

  Quote: ... murine IL-34 (100 ng/mL, R&D Systems),) ...
• Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-TrkB (R&D Systems, AF1494, 1:300), chicken anti-βgal (Abcam ...
• Monomeric amyloid-β inhibits microglial inflammatory activity in the brain via an APP/heterotrimeric G protein-mediated pathway

  Hyo Jun Kwon, Devi Santhosh, Zhen Huang, bioRxiv - Neuroscience 2023

  Quote: ... goat anti-MMP2 (R&D Systems; 5 μg/ml), rabbit anti-Calretinin (Chemicon ...
• Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging

  Sher Bahadur Poudel, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and 60ng/ml RANKL (R&D Systems; cat# 462TEC010) to induce osteoclastogenesis in the presence of different concentrations (0 ...
• Knock-down of a regulatory barcode shifts macrophage polarization destination from M1 to M2 and increases pathogen burden upon S. aureus infection

  Sathyabaarathi Ravichandran, et al., bioRxiv - Systems Biology 2023

  Quote: ... IL4 (#204-IL) were purchased from R&D Systems. THP-1 human monocytic cell line was obtained from National Centre for Cell Sciences ...
• Exogenous Recombinant N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B; ARSB) Inhibits Progression of B16F10 Cutaneous Melanomas and Modulates Cell Signaling

  Sumit Bhattacharyya, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Recombinant bioactive ARSB (R&D Systems, Minneapolis, MN, USA) in normal saline (n=12 ...
• An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

  Kai He, et al., bioRxiv - Cell Biology 2023

  Quote: ... GLI-3 (AF3690, R&D Systems, dilution 1:500), RAB11FIP5 (14594-1-AP ...
• A Dual Color Pax7 and Myf5 In Vivo Reporter to Investigate Muscle Stem Cell Heterogeneity in Regeneration and Aging

  Sara Ancel, et al., bioRxiv - Cell Biology 2023

  Quote: ... and α7-integrin (R&D Systems, #FAB3518N, 1/30). Myf5 subpopulations identified as Pax7-ZsGreen1 positive and Myf5-E2Crimson high or low were isolated using a Beckman Coulter Astrios Cell sorter.
• 3D human retinal organoid model for the study of early diabetic retinopathy

  Luisa de Lemos, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-OTX2 (1:100, AF1979, R&D Systems), rabbit anti-Vimentin (1:200 ...
• Ischemic and hemorrhagic stroke lesion environments differentially alter the glia repair potential of neural progenitor cell and immature astrocyte grafts

  Honour O Adewumi, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Cd13 (1:500, R&D Systems, AF2335); guinea pig anti-Iba-1 (1:500 ...
• Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin

  Marvin Reich, et al., bioRxiv - Neuroscience 2023

  Quote: ... or a rat anti-mPGRN (R&D Systems, MAB25571) antibody at 0.25 µg/mL followed by sulfo-tagged secondary antibodies (anti-rabbit and anti-rat respectively) ...
• Ischemic and hemorrhagic stroke lesion environments differentially alter the glia repair potential of neural progenitor cell and immature astrocyte grafts

  Honour O Adewumi, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Nestin (1:500, R&D Systems, AF2736); rabbit anti-P2ry12 (1:800 ...
• Ischemic and hemorrhagic stroke lesion environments differentially alter the glia repair potential of neural progenitor cell and immature astrocyte grafts

  Honour O Adewumi, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Sox9 (1:500, R&D Systems, AF3075); goat anti-Serpin A3N (1:200 ...
• Scalable projected Light Sheet Microscopy for high-resolution imaging of living and cleared samples

  Yannan Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-CD31 (1:50, BBA7, R&D Systems) and rabbit anti-Acta2 (1:1000 ...
• Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning

  Megha Maheshwari, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 40 ng/ml FGF-2 (R&D Systems) on poly-lysine (Sigma ...
• Designer small molecule control system based on Minocycline induced disruption of protein-protein interaction

  Ram Jha, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Human CD34 APC-conjugated antibody (R&D system, FAB7227A), Human CD34 Alexa Fluor® 488-conjugated antibody ...
• Human iPSC-derived neural stem cells display a radial glia-like signature in vitro and favorable long-term safety in transplanted mice

  Marco Luciani, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-SSEA4 APC-conjugated antibody (FAB1435a, R&D Systems). For Annexin V/7AAD analysis ...
• Enteric glial hub cells coordinate intestinal motility

  Marissa A. Scavuzzo, et al., bioRxiv - Neuroscience 2023

  Quote: ... 20ng/mL FGF2 (R&D Systems, 23-3FB-010M), and 1x penicillin/streptomycin (Thermo Fisher ...
• Ciliary ARL13B prevents obesity in mice

  Tiffany T. Terry, et al., bioRxiv - Genetics 2023

  Quote: ... rat anti-insulin (1:1000, R&D systems, MAB1417); rabbit anti-glucagon (1:2000 ...
• Ets1 and IL17RA cooperate to regulate autoimmune responses as well as skin immunity to Staphylococcus aureus

  Michael Battaglia, et al., bioRxiv - Immunology 2023

  Quote: ... 10μg/ml anti-TGFβ (R&D Systems, clone 1D11), 30ng/ml IL6 (Shenandoah Biotechnology) ...
• Engagement of sialylated glycans with Siglec receptors on myeloid suppressor cells inhibit anti-cancer immunity via CCL2

  Ronja Wieboldt, et al., bioRxiv - Immunology 2023

  Quote: ... Siglec-9 blocking antibody (Clone 191240, R&D Systems) was added at a final concentration of 10 µg/mL ...
• Border-forming wound repair astrocytes

  Timothy M. O’Shea, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Sox9 (1:800, AF3075; R&D Systems); rabbit anti-Sox9 (1:800 ...
• Border-forming wound repair astrocytes

  Timothy M. O’Shea, et al., bioRxiv - Neuroscience 2023

  Quote: ... sheep anti-S100a6 (1:300, AF4584; R&D Systems); rabbit anti-S100a6 (1:200 ...
• Border-forming wound repair astrocytes

  Timothy M. O’Shea, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Sox10 (1:500, AF2864; R&D Systems); guinea pig anti-tdT (RFP ...
• Non-genetic differences underlie variability in proliferation among esophageal epithelial clones

  Raúl A. Reyes Hueros, et al., bioRxiv - Systems Biology 2023

  Quote: ... Human recombinant DKK1 (rhDkk, R&D Systems, 5439-DK) was reconstituted at 100µg/mL in 0.1% bovine serum albumin (BSA ...
• Humoral correlates of protection against Mycobacterium tuberculosis following intravenous Bacille Calmette-Guérin vaccination in rhesus macaques

  Edward B. Irvine, et al., bioRxiv - Immunology 2023

  Quote: ... and Zaire ebolavirus glycoprotein (R&D Systems, 9016-EB).
• LINKIN-associated proteins necessary for tissue integrity during collective cell migration

  Chieh-Hsiang Tan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-ITFG1 antibody (ITFG1_Ab2) (R&D Systems, MAB89001), Rabbit anti-RUVBL1 antibody (Proteintech ...
• Epigenetic regulation of Leukocyte associated immunoglobulin-like receptors 1 and 2 by interferon signaling in macrophages and T cells

  Hannah K. Dorando, et al., bioRxiv - Immunology 2023

  Quote: ... 20ng/mL mouse IFN-β (8234MB010, R&D Systems), 20ng/mL mouse TNF-α (410MT010 ...
• Epigenetic regulation of Leukocyte associated immunoglobulin-like receptors 1 and 2 by interferon signaling in macrophages and T cells

  Hannah K. Dorando, et al., bioRxiv - Immunology 2023

  Quote: ... 20ng/mL mouse TNF-α (410MT010, R&D Systems), 100ng/mL LPS (L3012 ...
• Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration

  Giovanni S. Offeddu, et al., bioRxiv - Bioengineering 2023

  Quote: ... Recombinant human IL8 (#208-IL-010, R&D Systems), IL12 (#219-IL-005 ...
• Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype

  Rebecca L. Schmitz, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 20 ng/mL IL-4 (R&D Systems) (6 ...
• Vascularised Cardiac Spheroids-on-a-Chip for Testing the Toxicity of Therapeutics

  Stefania Di Cio, et al., bioRxiv - Bioengineering 2023

  Quote: ... Alexa Fluor® 488-anti-podocalyxin (R&D Systems); Phalloidin–Tetramethylrhodamine B isothiocyanate (Merck) ...
• Mechanically activated bone cells drive vessel formation via an extracellular vesicle mediated mechanism

  N. Shen, et al., bioRxiv - Bioengineering 2023

  Quote: ELISA kits for mouse VEGF (R&D Systems, UK) were used according to the manufacturer’s instructions ...
• A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance

  Felix van der Krift, et al., bioRxiv - Biochemistry 2023

  Quote: ... Organoids were maintained in Cultrex BME (R&D systems) and dissected using TrypLE (ThermoFisher ...
• Mechanisms of transcription control by distal enhancers from high-resolution single-gene imaging

  Lingling Cheng, et al., bioRxiv - Biophysics 2023

  Quote: ... 15% fetal bovine serum (FBS, R&D Systems, S10250), 0.1 mM 2-mercaptoethanol (Thermo Fisher Scientific 21985023) ...
• Human Vascularized Bile Duct-on-a Chip: A multi-cellular micro-physiological system for studying Primary Sclerosing Cholangitis

  Yu Du, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 100 ng/ml DKK-1 (R&D Systems)) with 10 µM Y27632 (Sigma-Aldrich) ...
• Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism

  Daniel Levy, et al., bioRxiv - Bioengineering 2023

  Quote: ... TNF-⍰ (DY410; R&D Systems Incorporated, Minneapolis, MN, USA), CCL5 (DY478 ...
• Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism

  Daniel Levy, et al., bioRxiv - Bioengineering 2023

  Quote: ... CCL5 (DY478; R&D Systems Incorporated, Minneapolis, MN, USA), and IFN-β (DY8234 ...
• Sustained In Vivo Perfusion of a Re-Endothelialized Tissue Engineered Kidney Graft in a Human-Scale Animal Model

  Joseph S. Uzarski, et al., bioRxiv - Bioengineering 2023

  Quote: ... epidermal growth factor (EGF) (R&D Systems, #236-EG), recombinant insulin-like growth factor (R3-IGF ...
• Multivalent, asymmetric IL-2-Fc fusions provide optimally enhanced regulatory T cell selectivity

  Brian Orcutt-Jahns, et al., bioRxiv - Systems Biology 2022

  Quote: ... or IL-15 (R&D Systems, 247-ILB-025) were diluted in RPMI-1640 in the absence of FBS ...
• The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo

  Martin S. Minns, et al., bioRxiv - Microbiology 2023

  Quote: ... and 10 ng/mL M-CSF (R&D Systems). On Day 2 and Day 4 ...
• Chronic demyelination of rabbit lesions is attributable to failed oligodendrocyte progenitor cell repopulation

  James J. M. Cooper, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse IgG2a anti-SOX2 (1:100, R&D Systems), mouse IgG1 anti-Ki67 (1:25 ...
• The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

  Thomas M. Li, et al., bioRxiv - Immunology 2023

  Quote: ... 37.5 ng IFN-κ (R&D Systems, Minneapolis, MN) was dissolved in DMSO (Sigma Aldrich ...
• Restoring glucose homeostasis with stomach-derived human insulin-secreting organoids

  Xiaofeng Huang, et al., bioRxiv - Cell Biology 2022

  Quote: ... was supplemented with 18% FBS (R&D systems, S11150), 10% R-Spondin-2 conditioned medium ...