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3751 - 3800 of 10000+ citations for R + SCH 23390 hydrochloride since 2020

• LncRNA Bigheart trans-activates gene expression in a feed forward mechanism that facilitates calcineurin-NFAT signaling in myocardial hypertrophy

  Nicolò Mangraviti, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 5 ng/ml Recombinant human BMP4 (R&D Systems), 9 ng/ml Recombinant Human/Mouse/rat Activin A (R&D Systems ...
• Traitor-virus-guided discovery of novel antiviral factors

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2023

  Quote: ... cells were treated with IFN-β (R&D Systems #8499-IF-010 ...
• Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB

  Moiz Munir, et al., bioRxiv - Microbiology 2023

  Quote: ... Recombinant human TNF-α (R&D systems 210-TA) treatment was done at 20 ng/mL for 15 minutes before lysing cells ...
• Protein tyrosine phosphatase receptor kappa regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity

  Eduardo H. Gilglioni, et al., bioRxiv - Cancer Biology 2023

  Quote: ... recombinant human IL6 (206-IL-010, R&D Systems), insulin ProZinc (NDC 0010-4499-01 ...
• PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function

  Hua He, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Goat anti-endomucin (R&D systems A45666: 1:1000), Rabbit anti-Pro SFTPC (Sigma AB3786 ...
• MET Inhibitor Capmatinib Radiosensitizes MET Exon 14-Mutated and MET-Amplified Non-Small Cell Lung Cancer

  Shrey Ramesh, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CometAssay® ES II electrophoresis system (R&D systems) was used as previously described (31) ...
• Human Induced Pluripotent Stem Cell based Hepatic-Modeling of Lipid metabolism associated TM6SF2 E167K variant

  Lanuza AP Faccioli, et al., bioRxiv - Cell Biology 2023

  Quote: ... 10 ng/mL BMP4 (R&D Systems, Minneapolis, MN), and 20 ng/mL FGF2 (BD ...
• Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway and dependent on low IGF1R level

  Sarah Hyllekvist Jørgensen, et al., bioRxiv - Cell Biology 2023

  Quote: ... Using human IGF1R PE-conjugated antibody (R&D systems), the IGF1R negatively stained population was bulk-sorted using SH800 cell sorter (Sony ...
• Identifying key underlying regulatory networks and predicting targets of orphan C/D box SNORD116 snoRNAs in Prader-Willi syndrome

  Rachel B. Gilmore, et al., bioRxiv - Genetics 2023

  Quote: ... 10 ng/mL BDNF (R&D Systems, 248-BD), 10 ng/mL GDNF (R&D Systems ...
• Following the p63/Keratin5 Basal Cells in the Sensory and Non-sensory Epithelia of The Vomeronasal Organ

  Noah M. LeFever, et al., bioRxiv - Developmental Biology 2023

  Quote: ... *Goat anti-Sox2 (1:800, AF2018, R&D Systems), *Chicken anti-Keratin5 (1:1500 ...
• Identifying key underlying regulatory networks and predicting targets of orphan C/D box SNORD116 snoRNAs in Prader-Willi syndrome

  Rachel B. Gilmore, et al., bioRxiv - Genetics 2023

  Quote: ... 10 ng/mL GDNF (R&D Systems, 212-GD), 10 ng/mL NT3 (PeproTech ...
• Collagen receptor GPVI-mediated platelet activation and pro-coagulant activity aggravates inflammation and aortic wall remodelling in abdominal aortic aneurysm

  T Feige, et al., bioRxiv - Cell Biology 2023

  Quote: ... a neutrophil elastase (ELA2) (#DY4517-05, R&D Systems), MMP2 (#MMP200 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... sheep anti-ESGP (1:1000; R&D Systems; AF4580) and rabbit anti-β-Tubulin (1:1000 ...
• CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia

  Sajeth Dinakaran, et al., bioRxiv - Cell Biology 2023

  Quote: ... and BMP10 (50 mg/kg; MAB2926, R&D System) were injected intraperitoneally (i.p. ...
• The Implant-Induced Foreign Body Response is Limited by CD13-Dependent Regulation of Ubiquitination of Fusogenic Proteins

  Mallika Ghosh, et al., bioRxiv - Cell Biology 2023

  Quote: ... Fusion inducing cytokines IL-4 (R&D Systems; 404ML010) and IL-13 (R&D Systems ...
• TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade

  Yan Xiong, et al., bioRxiv - Cell Biology 2023

  Quote: ... or Akt (Cat# 1775-KS-010, R&D systems) in the presence of 100 μM ATP ...
• Conformational diversity in class C GPCR positive allosteric modulation

  Giuseppe Cannone, et al., bioRxiv - Biochemistry 2023

  Quote: ... PAMs VU29 (med chem express) VU0409551 (R&D system), The mixture was then incubated at room temperature (RT ...
• NK cells contribute to resistance to anti-PD1 therapy in immune-excluded melanomas

  Ewout Landeloos, et al., bioRxiv - Cancer Biology 2023

  Quote: ... NKp46 (R&D Systems cat. no AF2225; 1:200), CD45 (Novus Biologicals cat ...
• Recognition of highly branched N-glycans of the porcine whipworm by the immune system

  Barbara Eckmair, et al., bioRxiv - Biochemistry 2023

  Quote: ... 5 µg/ml human MGL-Fc (R&D System) and 1 µg/ml human Dectin-2-Fc (Sino Biological ...
• Apoptotic signaling clears engineered Salmonella in an organ-specific manner

  Taylor J. Abele, et al., bioRxiv - Immunology 2023

  Quote: ... BID (1:500, rat, R&D Systems, Cat. MAB860), caspase-9 (1:750 ...
• Loss of ASD-Related Molecule Cntnap2 Affects Colonic Motility in Mice

  Beatriz G. Robinson, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Sox10 (1:2,000; R&D Systems, AF2864) and fluorophore-conjugated secondary antibodies (Jackson Labs and Molecular Probes).
• Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease

  Martí Colom-Cadena, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 5ng/mL GDNF (R&D Systems, 212-GD).
• Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke

  Siyi Zheng, et al., bioRxiv - Biophysics 2023

  Quote: ... goat anti-Cd13 (1:500, R&D Systems, AF2335); guinea pig anti-NeuN (1:500 ...
• Nested biofabrication: Matryoshka-inspired Intra-embedded Bioprinting

  Mecit Altan Alioglu, et al., bioRxiv - Bioengineering 2023

  Quote: ... supplemented with 20% (v/v) FBS (R&D Systems), 1% (v/v ...
• Acquired temozolomide resistance instructs patterns of glioblastoma behavior in gelatin hydrogels

  Victoria Kriuchkovskaia, et al., bioRxiv - Bioengineering 2023

  Quote: ... supplemented with 10% FBS (R&D Systems, Minneapolis, MN) and 0.2% v/v plasmocin (InvivoGen ...
• Fibroblast activation protein regulates natural killer cell migration, extravasation and tumor infiltration

  Allison A. Fitzgerald, et al., bioRxiv - Immunology 2023

  Quote: ... 100ng/mL CXCL9 (R&D systems, cat# 392-MG) was added to 400µL media plated in the lower well of the plate ...
• Prevention of tau accumulation through inhibition of hnRNP R-dependent axonal Mapt mRNA localization

  Abdolhossein Zare, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 µM dorsomorphin homolog 1 (4126, R&D Systems), 3 µM CHIR99021 (13122 ...
• Border-forming wound repair astrocytes

  Timothy M. O’Shea, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Gpc5 (1:200, AF2607; R&D Systems); rabbit anti-Gpx1 (1:200 ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 100 ng/ml Activin A (R&D System) for 24 hrs ...
• RSPO/LGR signaling mediates astrocyte-induced proliferation of adult hippocampal neural stem cells

  Daniela Valenzuela-Bezanilla, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-RSPO1 (AF3474, R&D Systems, 1:200), rabbit anti-RSPO2 (HPA024764 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Tsp4 (1:1000; R&D Systems AF2390). The next day ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-SPARC (1:1000; R&D Systems AF942), goat anti-Tsp1 (1:1000 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Tsp2 (1:1000; R&D Systems AF1635), goat anti-Tsp4 (1:1000 ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Tsp1 (1:1000; R&D Systems AF3074), goat anti-Tsp2 (1:1000 ...
• Gpr37 modulates the severity of inflammation-induced GI dysmotility by regulating enteric reactive gliosis

  Keiramarie Robertson, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-Sox10 (1:500; R&D Systems, AF2864), human anti-HuC/D (ANNA1 ...
• Skeletal Muscle Specific PolG Dysfunction Activates the Integrated Stress Response and Promotes a Cachexia like Phenotype

  Simon T Bond, et al., bioRxiv - Physiology 2024

  Quote: Commercial ELISA kits for FGF21 (R&D Systems, #MF2100) and GDF15 (R&D Systems ...
• The chromatin remodeler CHD3 is highly expressed in mature neurons and regulates genes involved in synaptic development and function

  Joery den Hoed, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat-anti-SOX2 (1:500, af2018, R&D systems); mouse anti-TRA-1-60 (1:200 ...
• Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury

  Quentin Delarue, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat anti-mMMR (CD206, R&D systems, AF2535, RRID:AB_2063012), rat anti-B-lymphocyte activation antigen B7-2 (CD86 ...
• CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and uptake of synaptic material

  Olivia M Teter, et al., bioRxiv - Neuroscience 2024

  Quote: Conjugated CD38 antibody (R&D Systems; Cat. No. FAB2404P) diluted in FACS buffer was added to the cells for a final dilution of 1:200 ...
• Trehalose-based coacervates for local bioactive protein delivery to the central nervous system

  Laboni F Hassan, Riya Sen, Timothy M O’Shea, bioRxiv - Bioengineering 2024

  Quote: ... anti-Goat Cd13 (R&D systems, AF2335, 1:500); anti-Rat Ly6b2 (BioRad ...
• Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia

  Benjamin J. Rodems, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 10 ng/mL IL-6 (R&D Systems). Cells were retrovirally infected with MSCV- MLL-AF9-IRES-tNGFR and MSCV-NRASG12V-IRES-YFP cells were harvested 48 hr after infection ...
• Engineering Memory T Cells as a platform for Long-Term Enzyme Replacement Therapy in Lysosomal Storage Disorders

  Kanut Laoharawee, et al., bioRxiv - Bioengineering 2024

  Quote: ... anti-human CD3 epsilon antibody (MAB10670; R&D Systems), or anti-human alpha-L-Iduronidase antibody (AF4119 ...
• Enhancing oncolytic virotherapy by exosome-mediated microRNA reprograming of the tumour microenvironment

  Victoria A. Jennings, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse and human Arginase-1-FITC (R&D systems), PD-L1-FITC (MIH1) ...
• Antibiotic treatment induces microbiome dysbiosis and reduction of neuroinflammation following traumatic brain injury in mice

  Hannah Flinn, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-rat F4/80 (1:200, R&D Systems), anti-rabbit P2Y12 (1:500 ...
• Cellular and molecular events organizing the assembly of tertiary lymphoid structures in glioblastoma

  Alessandra Vaccaro, et al., bioRxiv - Cancer Biology 2024

  Quote: ... goat anti-mouse CD31 (clone AF3628, R&D Systems); donkey-anti-goat-AF647 (#A-21447 ...
• Engineered 3D Hydrogel Matrices to Modulate Trophoblast Stem Cell-Derived Placental Organoid Phenotype

  Emily M. Slaby, et al., bioRxiv - Bioengineering 2024

  Quote: ... 100 ng/mL FGF2 (R&D Systems catalog #3718FB01M), 50 ng/mL EGF (R&D Systems catalog #236-EG-01M) ...
• Phenomics demonstrates cytokines additive induction of epithelial to mesenchymal transition

  Alphonse Boché, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or TNFα (R&D Systems, 210-TA-005/CF) and TGFβ1 at 10ng/mL each ...
• Abnormal morphology and synaptogenic signaling in astrocytes following prenatal opioid exposure

  Ethan B. Niebergall, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-Hevin (1:2000; R&D Systems AF2836), mouse anti-SPARC (1:1000 ...
• Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells

  Linda V. Sinclair, et al., bioRxiv - Immunology 2024

  Quote: ... IL-12 + IL-18 (20ng/ml; R&D Systems) or no cytokine for 24h ...
• Monitoring macrophage polarization with gene expression reporters and bioluminescence phasor analysis

  Giulia Tedeschi, et al., bioRxiv - Bioengineering 2024

  Quote: ... and IL-13 (20 ng/mL, R&D Systems). After 18–24 h incubation ...