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3101 - 3150 of 10000+ citations for R + SCH 23390 hydrochloride since 2020

• Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation

  Damien Dufour, et al., bioRxiv - Physiology 2022

  Quote: ... HA-SUMO vinyl sulfone (R&D Systems, Minneapolis, MN) was added for the SUMO-VS condition to the concentration of 5 µM for both SUMO1 and SUMO2.
• Genetically-Modified Macrophages Accelerate Myelin Repair

  Marie-Stephane Aigrot, et al., bioRxiv - Neuroscience 2022

  Quote: ... rat anti-Sema3F (R&D Systems, MAB3237, 1:50); rabbit anti-P2Y12 (Anaspec ...
• Release of acidic store calcium is required for effective priming of the NLRP3 inflammasome

  Nick Platt, et al., bioRxiv - Immunology 2022

  Quote: ... incubated with anti-IL-1b antibody (R&D Systems) overnight at 4°C ...
• Single-cell RNA sequencing identifies phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow

  Hongzhe Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 0.01 µg/ml TGF-ß3 (R&D Systems). Pellets were paraformaldehyde (PFA)-fixed and frozen in O.C.T ...
• ATPase activity of DFCP1 controls selective autophagy

  Viola Nähse, et al., bioRxiv - Cell Biology 2022

  Quote: ... and Torin1 (#4247, Bio-Techne R&D systems Europe) at 50 nM.
• Collagen-VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche

  Vasileios Papalazarou, et al., bioRxiv - Cancer Biology 2022

  Quote: Human Fibronectin Protein (1918-FN-02M, R&D Systems), Fibronectin bovine plasma (F1141 ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Rat anti-SCGB3A1 (1:200, R&D Systems, MAB2954); Rat anti-SCGB3A2 (1:200 ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Rat anti-SCGB3A2 (1:200, R&D Systems, MAB3465); Rabbit anti-Ki67 (1:400 ...
• An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

  Wenguang Yin, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Goat anti-SOX9 (1:500, R&D Systems, AF3075); Rat anti-Cd140a (1:100 ...
• Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

  Anna Yoney, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GSC (goat polyclonal, R&D Systems AF4086, 1:200). Cells were incubated with secondary antibodies (diluted 1:1000) ...
• TGF-β-R2 is required for HBP induced acute lung injury and vascular leakage for TGF-β/Smad/Rho signaling pathway activation

  Zixuan Liu, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Recombinant human HBP (2200-SE-050, R&D Systems), protease inhibitor cocktail (HY-K0010) ...
• Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination

  Lin Pan, et al., bioRxiv - Neuroscience 2022

  Quote: ... PDGFRα (R&D Systems, cat #AF1062, dilution 1:500), Olig2 (Millipore ...
• Resident T cells orchestrate adipose tissue remodeling in a site peripheral to infection

  Agnieszka M. Kabat, et al., bioRxiv - Immunology 2022

  Quote: ... or TSLP (R&D Systems, #555-TS, 50ng/ml) where indicated ...
• CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation

  Pei-Shan Sung, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TLR2 mAb (100 μg/ml, R&D system), or a mixture of anti-CLEC5A mAb and anti-TLR2 mAb for 30 min at room temperature before incubation with SARS-CoV-2 ...
• Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model

  Jian Hang Lam, et al., bioRxiv - Immunology 2022

  Quote: ... mouse anti-S1 mAb (clone 1035206; R&D Systems) was diluted 1:100 and applied to each well ...
• Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation

  Jack A. Bibby, et al., bioRxiv - Immunology 2022

  Quote: ... anti-sheep IgG-NL557 (R&D Systems, 1:500). IFNγ expression was analyzed using the IFN-γ Secretion Assay (PE ...
• Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain

  Anthony Fernández-Castañeda, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-PDGFRa (1:500; R&D Systems AF1062), mouse anti-CC1 (1:100 ...
• Hyperactivation of YAP/TAZ drives alterations in mesangial cells through stabilization of N-MYC in diabetic nephropathy

  Seunghyeok Choi, et al., bioRxiv - Pathology 2022

  Quote: ... anti-VE-cadherin (goat, polyclonal, AF1002, R&D systems), anti-ICAM2 (rat ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... rat anti-Vimentin (1:500; R&D Systems, MAB2105); rat anti-Cd44 (IM7 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Sox9 (1:1000, R&D systems, AF3075); goat anti-Dppa4 (1:2000 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Dppa4 (1:200; R&D Systems, AF3730), Rabbit anti-Id3 (1:200 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Cd13 (1:200, R&D systems, AF2335); rat anti-Galectin-3 (1:200 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Nestin (1:2000, R&D Systems, AF2736); rabbit alpha-smooth muscle actin (α-Sma ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Sox9 (1:500, R&D systems, AF3075); rabbit Aldh1l1 (1:1000 ...
• Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype

  T.M. O’Shea, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Oct4 (1:500, R&D systems, AF1759); goat anti-Sox9 (1:500 ...
• Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

  Hyosung Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... E-Selectin (AF724, R&D systems, 1:1000 dilution), and GAPDH (D16H11 ...
• Stable iPSC-derived NKX2-1⁺ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

  Renee F.C. Hein, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 200ng/mL NOGGIN (R&D Systems, Cat#6057-NG), 2uM CHIR99021 (APExBIO ...
• Stable iPSC-derived NKX2-1⁺ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

  Renee F.C. Hein, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 50ng/mL BMP4 (R&D Systems, Cat#314-BP) was added on day 1 ...
• Stable iPSC-derived NKX2-1⁺ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

  Renee F.C. Hein, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 100ng/mL ActivinA (R&D Systems, Cat#338-AC) was added in RPMI 1640 media (Thermo Fisher ...
• Stable iPSC-derived NKX2-1⁺ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

  Renee F.C. Hein, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 10ng/mL FGF7 (R&D Systems, Cat#251-KG) and 3µM CHIR99021(APExBIO ...
• Combined single-cell RNA-seq profiling and enhancer editing reveals critical spatiotemporal controls over thalamic nuclei formation in the murine embryo

  Kiya W. Govek, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti- Sox2 (1:100, R&D Systems, MAB2018), rabbit anti-Sox2 (1:300 ...
• Mesenchymal stem cells support human vascular endothelial cells to form vascular sprouts in human platelet lysate-based matrices

  Eva Rossmanith, et al., bioRxiv - Bioengineering 2022

  Quote: ... fibronectin (2 μg/ml clone MAB1918, R&D Systems), or a rabbit mAb specific for laminin (5 μg/ml clone ab11575 ...
• The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging

  Erna Raja, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Recombinant mouse interleukin-6 (R&D Systems, 406-ML) was added to the culture medium at the indicated concentration.
• Human MAIT cells show clonal diversity but transcriptional and functional homogeneity

  Lucy C. Garner, et al., bioRxiv - Immunology 2022

  Quote: ... and IL-18 (50 ng/ml; R&D Systems) were added to the cytokine stimulation condition ...
• Heterogeneity of Inflammation-associated Synovial Fibroblasts in Rheumatoid Arthritis and Its Drivers

  Melanie H Smith, et al., bioRxiv - Immunology 2022

  Quote: ... with 10% Fetal bovine serum (R&D systems S11550) as well as 1% penicillin/streptomycin (ThermoFisher Scientific 15070063 ...
• Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel

  Jianlong Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... goat anti-GFRα2 (1:200; R&D Systems AF429); and vasoactive intestinal peptide antibody anti-VIP (1:100 ...
• Mesenchymal Stromal Cells Donate Mitochondria to Articular Chondrocytes Exposed to Mitochondrial, Environmental, and Mechanical Stress

  Megan J. Fahey, et al., bioRxiv - Cell Biology 2022

  Quote: ... media with 10% fetal bovine serum (R&D systems), 1% Penicillin-Streptomycin (Corning ...
• Phenotypic dissection of epithelial lineages and therapeutic manipulation of differentiation programs in human Adenoid Cystic Carcinomas (ACCs)

  Sara Viragova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 10 µM Y-27632 (R&D Systems, 1254), and plated in transwell inserts (Griener Thincert ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... 100 ng ml-1 CXCL12-α (R&D Systems) and/or 100 nM VUF11207 (Cayman Chemical ...
• Single-hit genome edition for expression of single-chain immunoglobulins by edited B cells

  Natsuko Ueda, et al., bioRxiv - Immunology 2022

  Quote: ... 50 U/ml recombinant IL-2 (R&D Systems) and 100 ng/ml recombinant human soluble CD40L (Immunex ...
• Single-hit genome edition for expression of single-chain immunoglobulins by edited B cells

  Natsuko Ueda, et al., bioRxiv - Immunology 2022

  Quote: ... and 12 ng/ml IL-10 (R&D Systems) in order to promote the differentiation into plasmablasts (“2nd step differentiation cocktail”)8 ...
• Single-hit genome edition for expression of single-chain immunoglobulins by edited B cells

  Natsuko Ueda, et al., bioRxiv - Immunology 2022

  Quote: ... and 12 ng/ml IL-10 (R&D Systems).
• Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina

  Nguyet Le, et al., bioRxiv - Neuroscience 2022

  Quote: ... Goat anti-Otx2 (R&D Systems, #AF1979, 1:200), Rabbit anti-Rbpms (ThermoFisher ...
• The Modular µSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro

  Molly C. McCloskey, et al., bioRxiv - Bioengineering 2022

  Quote: ... and human fibronectin (5 µg/cm2, R&D Systems) for 1 hour at 37°C ...
• Combinatorial T cell engineering eliminates on-target off-tumor toxicity of CD229 CAR T cells while maintaining anti-tumor activity

  Erica R. Vander Mause, et al., bioRxiv - Bioengineering 2022

  Quote: ... 5 μg/ml recombinant human CD229 (R&D Systems) was immobilized on a black 96-well plate (Greiner Bio-One ...
• Receptor binding domain of SARS-CoV-2 is a functional αv-integrin agonist

  Emma G. Norris, et al., bioRxiv - Cell Biology 2022

  Quote: ... and α5β1 (3230-A5) were from R&D Systems.
• HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

  Jenny Horndahl, et al., bioRxiv - Cell Biology 2022

  Quote: For experiments using TNF (R&D Systems, Minneapolis, Canada), TNF (ranging from 5-50 ng/ml ...
• A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain

  Sofia Madsen, et al., bioRxiv - Cell Biology 2022

  Quote: ... SOX2 goat (1:500, R&D Systems AF2018-SP), tdTomato goat (1:500 ...
• Islet Gene View - a tool to facilitate islet research

  Olof Asplund, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and TNF-α (10 ng/ml, R&D Systems) in the presence of IncuCyte Caspase-3/7 green reagent (IncuCyte ...
• Islet Gene View - a tool to facilitate islet research

  Olof Asplund, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and IFN-γ (50 ng/ml, R&D Systems) and TNF-α (10 ng/ml ...