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2951 - 3000 of 10000+ citations for R + SCH 23390 hydrochloride since 2020

• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and 500 U/mL IFN-α (R&D Systems). Cells were cultured in this media for 3 additional days.
• Crosstalk between Fat Mass and Obesity-related (FTO) and multiple WNT signaling pathways

  Hyunjoon Kim, Soohyun Jang, Young-suk Lee, bioRxiv - Molecular Biology 2021

  Quote: ... human/mouse Wnt5a (R&D Systems #645-WN-010) and human R-Spondin1 (R&D Systems #4645-RS-025 ...
• The Role of Notch Signaling in Endometrial Mesenchymal Stromal/Stem-like Cells Maintenance

  Sisi Zhang, et al., bioRxiv - Cell Biology 2022

  Quote: ... recombinant human WNT3A (0.01 μg/ml, R&D Systems) or recombinant human WNT5A (0.01 μg/ml ...
• Decoding the activated stem cell phenotype of the vividly maturing neonatal pituitary

  Emma Laporte, et al., bioRxiv - Developmental Biology 2022

  Quote: ... WNT3A (200 ng/ml; R&D systems, Minneapolis, MN), WNT5A (100 ng/ml ...
• The antimicrobial peptide cathelicidin is critical for the development of Th17 responses in severe inflammatory disease

  Katie J Smith, et al., bioRxiv - Immunology 2022

  Quote: ... CD31 (rat polyclonal, R&D Systems, #AF3628, 1:100), peripheral node addressin (MECA-79 ...
• The antimicrobial peptide cathelicidin is critical for the development of Th17 responses in severe inflammatory disease

  Katie J Smith, et al., bioRxiv - Immunology 2022

  Quote: Concentrations of mouse IL-23 (R&D Systems, #DY1887) and IL-12 (R&D Systems #M1270 ...
• Human NLRP1 is activated by ZAKɑ-driven ribotoxic stress response

  Kim S. Robinson, et al., bioRxiv - Immunology 2022

  Quote: ... human IL-6 ELISA kit (R&D Systems, D6050) and a human IL-8/CXCL8 ELISA kit (R&D Systems ...
• IL-33 regulates age-dependency of long-term immune dysfunction induced by sepsis

  David F. Colon, et al., bioRxiv - Immunology 2022

  Quote: ... IL4 (10 ng/mL, M2-like, R&D Systems) or medium (M0 macrophages) ...
• Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

  Ryan J. Geusz, et al., bioRxiv - Genomics 2020

  Quote: ... and human EGF were purchased from R&D systems. Other added components included FBS (HyClone) ...
• Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

  Aereas Aung, et al., bioRxiv - Immunology 2021

  Quote: ... or Cathepsin L (1515-CY-010, R&D Systems). The buffer pH for digestion was adjusted based on manufacturer’s protocol and were 8.5 ...
• A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates

  Ryan J. Geusz, et al., bioRxiv - Genomics 2020

  Quote: ... goat anti-SOX17 (1:300 dilution, R&D systems); goat anti-HNF4A (1:1000 dilution ...
• A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates

  Ryan J. Geusz, et al., bioRxiv - Genomics 2020

  Quote: ... and human EGF were purchased from R&D systems. Other added components included FBS (HyClone) ...
• A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates

  Ryan J. Geusz, et al., bioRxiv - Genomics 2020

  Quote: ... goat anti-FOXA2 (1:300 dilution, R&D systems); goat anti-SOX17 (1:300 dilution ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... supplemented with BMP4 (40 ng/mL, R&D Systems), ACTIVIN A (30 ng/mL ...
• A modified porous silicon microparticle promotes mucosal delivery of SARS-CoV-2 antigen and induction of potent and durable systemic and mucosal T helper 1 skewed protective immunity

  Awadalkareem Adam, et al., bioRxiv - Immunology 2021

  Quote: ... or rSARS-CoV-2 spike protein (R&D Systems). To detect total IgG or IgA expressing B cells ...
• FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes

  Christopher Yanucil, et al., bioRxiv - Molecular Biology 2021

  Quote: ... mouse FGF21 (8409-FG-025/CF, R&D Systems), human soluble β-klotho (5889-KB-050/CF ...
• CBL mutations promote activation of PI3K/AKT signaling via LYN kinase

  Roger Belizaire, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 10ng/mL GM-CSF (R&D Systems, 215-GM) with 250nM dasatinib (Selleck Chemicals ...
• Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase

  Johan A Slotman, et al., bioRxiv - Developmental Biology 2020

  Quote: ... we used goat antibody anti-SYCP3 (R&D Systems), mouse monoclonal antibody anti-DMC1 (Abcam ab1837) ...
• Production and Purification of Endogenously Modified tRNA-Derived Small RNAs

  Aleksej Drino, et al., bioRxiv - Biochemistry 2020

  Quote: For cleavage reactions using recombinant ANG (R&D Systems), 500 ng of total RNA or purified tRNA-GlyGCC were melted for 5 minutes at 70 °C in H2O ...
• Neutralizing PD-L1 and PD-L2 Enhances the Efficacy of Immune Checkpoint Inhibitors in Ovarian Cancer

  Yu Rebecca Miao, et al., bioRxiv - Cancer Biology 2020

  Quote: ... αHuman PD-L1 1:500 (#AF154, R&D systems,
• Deletion of Sphingosine 1-Phosphate Receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis

  Ryan Jorgensen, et al., bioRxiv - Physiology 2020

  Quote: ... or Contactin 2 (1:1000, R&D Systems, AF4439). Membranes were incubated with secondary antibody Goat anti-rabbit IgG-HRP (1:1000 ...
• AGC kinase members phosphorylate ubiquitin

  Carl-Christian Kolbe, Eicke Latz, bioRxiv - Biochemistry 2020

  Quote: ... or GST-ubiquitin (R&D Systems; Cat. # U-540) were solubilized in 50 mM HEPES (pH= 7.4) ...
• AGC kinase members phosphorylate ubiquitin

  Carl-Christian Kolbe, Eicke Latz, bioRxiv - Biochemistry 2020

  Quote: ... or GST-ubiquitin (R&D Systems; Cat. # U-540) were incubated in 20 µl standard kinase reaction buffer (Cell Signaling Technology ...
• Generation of neuronal diversity from common progenitors via Notch signaling in the cerebellum

  Tingting Zhang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-Olig2 (1:500, R&D systems, AF2418) and Guinea pig anti-Tbr1 (1:500 ...
• Material-Driven Fibronectin Assembly Rescues Matrix Defects due to Mutations in Collagen IV in Fibroblasts

  Elie Ngandu Mpoyi, et al., bioRxiv - Bioengineering 2020

  Quote: ... human integrin alpha V/CD51 antibody (R&D Systems), mouse vinculin hVIN-1 (Sigma-Aldrich ...
• Imaging Renal Ultrastructure using a Fast and Simple Optical Clearing and Swelling Protocol

  David Unnersjö-Jess, et al., bioRxiv - Pathology 2020

  Quote: ... sheep polyclonal antibody to nephrin (R&D systems, AF4269) used at a dilution of 1:50 ...
• Comprehensive Benchmarking of CITE-seq versus DOGMA-seq Single Cell Multimodal Omics

  Zhongli Xu, et al., bioRxiv - Genomics 2021

  Quote: ... and 50 ng/ml IL-23 (R&D Systems), and either 1 uM Prostaglandin E2 (PGE2 ...
• Genoppi: an open-source software for robust and standardized integration of proteomic and genetic data

  Greta Pintacuda, et al., bioRxiv - Genetics 2020

  Quote: ... glial cell-derived neurotrophic factor (GDNF) (R&D Systems 248-BD/CF ...
• High throughput functional screening for next generation cancer immunotherapy using droplet-based microfluidics

  Yuan Wang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and 10 ng/mL IL-4 (R&D Systems). Suspended cells were harvested and confirmed to be dendritic cells by CD11c expression ...
• The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels

  Andrew P. Porter, et al., bioRxiv - Cell Biology 2020

  Quote: Tiam1 (R&D Systems, AF5038, sheep 1:200, methanol)
• CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation

  Daniel Hwang, et al., bioRxiv - Immunology 2021

  Quote: Recombinant CSF-1 (4 µg/dose; R&D Systems) was given to EAE mice on days 4 ...
• FLAMs: A self-replicating ex vivo model of alveolar macrophages for functional genetic studies

  Sean Thomas, et al., bioRxiv - Immunology 2021

  Quote: ... containing 10% fetal bovine serum (FBS, R&D Systems), 1% penicillin-streptomycin (P/S ...
• CRTC2 regulates plasma cell metabolism and survival

  Jason S Hong, et al., bioRxiv - Immunology 2021

  Quote: ... and 5 ng/ml IL-5 (R&D Systems) to monitor B cell processes during B cell differentiation or to monitor differentiation with increased plasma cell (PC ...
• CRTC2 regulates plasma cell metabolism and survival

  Jason S Hong, et al., bioRxiv - Immunology 2021

  Quote: ... and 25 ng/ml IL-4 (R&D Systems) or with 0.1 ug/ml CD40L ...
• Constitutively active TrkB kinase signalling reduces actin filopodia dynamics and cell migration

  Rohini Gupta, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-TrkB (R&D Systems, AF1494, 1:1,000), rabbit anti-pY674/675-TrkA (anti-pY706/707– TrkB ...
• A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

  Sean M. Gross, et al., bioRxiv - Systems Biology 2021

  Quote: ... 10 ng/ml OSM (R&D Systems #8475-OM), 20 ng/ml BMP2 (R&D Systems #355-BM ...
• A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

  Sean M. Gross, et al., bioRxiv - Systems Biology 2021

  Quote: ... 20 ng/ml BMP2 (R&D Systems #355-BM) + 10 ng/ml EGF ...
• A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

  Sean M. Gross, et al., bioRxiv - Systems Biology 2021

  Quote: ... 20 ng/ml IFNY (R&D Systems #258-IF) + 10 ng/ml EGF ...
• A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

  Sean M. Gross, et al., bioRxiv - Systems Biology 2021

  Quote: ... 20 ng/ml EGF (R&D Systems #236-EG), 0.5 μg/ml hydrocortisone (Sigma #H-4001) ...
• A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

  Sean M. Gross, et al., bioRxiv - Systems Biology 2021

  Quote: ... 10 ng/ml TGFβ (R&D Systems #240-B) + 10 ng/ml EGF.
• A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses

  Sean M. Gross, et al., bioRxiv - Systems Biology 2021

  Quote: ... 40 ng/ml HGF (R&D Systems #294-HG), 10 ng/ml OSM (R&D Systems #8475-OM) ...
• Spatially-Resolved Live Cell Tagging and Isolation Using Protected Photoactivatable Cell Dyes

  Alex S Genshaft, et al., bioRxiv - Systems Biology 2020

  Quote: ... ROCK inhibitor Y-27632 (10 μM, R&D Systems) was added for the first two days of culture only ...
• Synthetic genomic reconstitution reveals principles of mammalian Hox cluster regulation

  Sudarshan Pinglay, et al., bioRxiv - Synthetic Biology 2021

  Quote: ... and 3 μM GSK3 inhibitor (R&D Systems, CHIR99021). mESC medium was made from Knockout DMEM (Gibco 10829018) ...
• Secreted SARS-CoV-2 ORF8 modulates the cytokine expression profile of human macrophages

  Nisha Kriplani, et al., bioRxiv - Microbiology 2021

  Quote: ... human type I IFN (R&D systems, 11415-1) was typically added at a final concentration of 150 U/ml ...
• Microbiota-derived short chain fatty acids promote Aβ plaque deposition

  Alessio Vittorio Colombo, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-ADAM10 N-terminal (1:1000; R&D Systems) and anti-BACE1 (1:1000 ...
• Loss of PI3-kinase activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration and intestinal homeostasis

  Prasun Guha, et al., bioRxiv - Cell Biology 2020

  Quote: ... Antigen Retrieval Reagent-Universal was from R&D systems. EZview™ Red Protein G Affinity Gel was from Sigma Aldrich ...
• Endothelial Unc5B controls blood-brain barrier integrity

  Kevin Boyé, et al., bioRxiv - Cell Biology 2021

  Quote: ... Human or Rat Unc5B-ECD-Fc (R&D Systems) were immobilized on a CM5 sensor chip ...
• The DCC receptor regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

  Laura Morcom, et al., bioRxiv - Neuroscience 2020

  Quote: ... 200ng of recombinant mouse NTN1 protein (R&D Systems) was diluted in sterile PBS and added to cultures within 2 mL media ...
• SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species

  Dhiraj Kumar Singh, et al., bioRxiv - Immunology 2020

  Quote: ... LAG-3 (Polyclonal, R&D Systems, Minneapolis, MN, USA), CD123 (clone 7G3) ...
• The low-density lipoprotein receptor-related protein-1 is essential for Dengue virus infection

  Vivian Huerta, et al., bioRxiv - Biochemistry 2020

  Quote: ... sLRP1_CIII and sLRP_CIV were purchased from R&D Systems, USA ...