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1701 - 1750 of 10000+ citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

  Sarah R Anderson, et al., bioRxiv - Neuroscience 2022

  Quote: ... PE CCR2 1:200 (R&D Systems FAB5538P), and APC Ly6C 1:200 (BD Bioscience 560595) ...
• iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

  Alba Tristán-Noguero, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-FOXA2 (1:50; R&D Systems), goat anti-Nanog (1:25 ...
• iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

  Alba Tristán-Noguero, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Nanog (1:25; R&D Systems), mouse anti-OCT3/4 (1:25 ...
• Mural norrin/β-catenin signaling regulates Lama2 expression to promote neurovascular unit assembly

  Saptarshi Biswas, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-Pdgfrβ (1:200; R&D Systems; Minneapolis ...
• Phosphatidylserine within the Viral Membrane Enhances Chikungunya Virus Infectivity in a Cell-type Dependent Manner

  Kerri L. Miazgowicz, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-hTIM1(1:100, AF1750, R&D Systems), or anti-CLEC4M (L-SIGN/CD299 ...
• Epidermal basal domains organization highlights skin robustness to environmental exposure

  Sangeeta Ghuwalewala, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-Caspase3 (1:4,000, R&D Systems AF835), gamma-H2AX (1:4,000 ...
• LCK Regulates Homologous Recombination DNA Repair Identifying a New Target for Sensitizing PARP Inhibitors in HR Proficient Ovarian Cancer

  Goutam Dey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... P-LCK 394 (1:1000 R&D Systems), RAD51 (1:1000 ...
• Astroglial CD38 regulates social memory and synapse formation through SPARCL1 in the medial prefrontal cortex

  Tsuyoshi Hattori, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-CD38 (AF4947, R&D systems, 1:300), anti-β-actin (013-24553 ...
• Astroglial CD38 regulates social memory and synapse formation through SPARCL1 in the medial prefrontal cortex

  Tsuyoshi Hattori, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-SPARCL1 (AF2836, R&D systems, 1:2000); anti-BDNF (ab108319 ...
• CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism

  Nefeli Slavi, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-Msx1 (1:100, R&D systems), mouse anti-Cav1.3 (1:100 ...
• IFT20 is critical for early chondrogenesis during endochondral ossification

  Hiroyuki Yamaguchi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-GLI1 (R&D systems; AF3455, 1:500), anti-SOX9 (Santa cruz biotechnology ...
• Met/HGFR triggers detrimental reactive microglia in TBI

  Rida Rehman, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rat anti-Vitronectin (1:100, R&D systems), Mouse anti-Integrin beta 3 (1:50 ...
• Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice

  Anna Katharina Schlusche, et al., bioRxiv - Neuroscience 2021

  Quote: ... Tuj1 (mouse, MAB1195, R&D Systems, 1:100) as a marker for early neurons ...
• Cell types and clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics

  Michael Ratz, et al., bioRxiv - Neuroscience 2021

  Quote: ... Sox9 (goat, 1:300, R&D Systems, AB_2194160), Sox10 (goat ...
• Cell types and clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics

  Michael Ratz, et al., bioRxiv - Neuroscience 2021

  Quote: ... Sox10 (goat, 1:300, R&D Systems, AB_442208) or Iba1 (rabbit ...
• L-Thyroxine improves vestibular compensation in a rat model of acute peripheral vestibulopathy

  Guillaume Rastoldo, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Sox2 (1:100, R&D Systems), rabbit anti-TRα (1:200 ...
• CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

  Megan Lo, et al., bioRxiv - Biochemistry 2021

  Quote: ... 1 μg/mL recombinant SHH (R&D Systems), 30 μM 20(S)-hydroxycholesterol (Cayman Chemicals) ...
• Blood flow modeling reveals improved collateral artery performance during mammalian heart regeneration

  Suhaas Anbazhakan, et al., bioRxiv - Bioengineering 2021

  Quote: ... and Podocalyxin (1:1000, R&D Systems MAB1556) were prepared in PBS with 5%DMSO ...
• Tle4 controls both developmental acquisition and postnatal maintenance of corticothalamic projection neuron identity

  Maria J. Galazo, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1:100 (R&D Systems Cat# AF2156, RRID:AB_2153894); rabbit anti-TBR1 ...
• Arginine 65 methylation of Neurogenin 3 by PRMT1 is a prerequisite for development of hESCs into pancreatic endocrine cells

  Gahyang Cho, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-SOX17 (1:400, R&D Systems), mouse anti-GATA4 (1:400 ...
• Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling

  M. Micaela Sartoretti, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-Sox9 (AF3075, R&D Systems; 1:200), anti-Nfia (39397 ...
• Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration

  Ermelinda Porpiglia, et al., bioRxiv - Cell Biology 2022

  Quote: ... we added recombinant thrombospondin-1 (R&D Systems) at the indicated concentrations 24 hours post isolation and cultured the cells for a total of 6 days ...
• The integrated stress response induces a common cell-autonomous death receptor 5-dependent apoptosis switch

  Nerea L. Muniozguren, et al., bioRxiv - Cell Biology 2022

  Quote: ... or 1 μg/ml FcDR5 (R&D systems) as indicated ...
• Salinomycin disturbs Golgi apparatus function and specifically affects cells in epithelial-to-mesenchymal transition

  Marko Marjanović, et al., bioRxiv - Cancer Biology 2022

  Quote: ... proN-cadherin (1:500, R&D Systems, AF1388), EGFR (1:1000 ...
• Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells

  Yueyang Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... 40 uM AIP (R&D SYSTEMS #5959/1), 50 μM CAS 1090893 (Millipore ...
• Morphological profiling of human T and NK lymphocytes identifies actin-mediated control of the immunological synapse

  Yolla German, et al., bioRxiv - Immunology 2020

  Quote: ... 1 µg/ml NKp30 (R&D systems, MAB18491) and 1 µg/ml NKp46 (BD Biosciences ...
• Conserved and divergent features of DNA methylation in embryonic stem cell-derived neurons

  Sally Martin, et al., bioRxiv - Genomics 2020

  Quote: ... with 1:200 N2 Supplement (R&D Systems), 1:100 B27 supplement without retinoic acid (Miltenyi Biotec ...
• Heat Shock Protein 27 Immune Complex Altered Signaling and Transport (ICAST): Novel Mechanisms of Attenuating Inflammation

  Chunhua Shi, et al., bioRxiv - Pathology 2020

  Quote: ... and anti-CD36 (R&D System, 1:1000) antibodies with demonstrable affinities (see Western blots ...
• The transcription factor Rreb1 regulates epithelial architecture and invasiveness in gastrulating mouse embryos

  Sophie M. Morgani, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Sox17 (RRID:AB_355060, R&D Systems, AF1924, 1:100), ZO-1 (RRID:AB_87181 ...
• The transcription factor Rreb1 regulates epithelial architecture and invasiveness in gastrulating mouse embryos

  Sophie M. Morgani, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Snail (RRID:AB_2191738, R&D Systems, AF3639, 1:50), Sox2 (RRID:AB_11219471 ...
• The transcription factor Rreb1 regulates epithelial architecture and invasiveness in gastrulating mouse embryos

  Sophie M. Morgani, et al., bioRxiv - Developmental Biology 2020

  Quote: ... CD105 (RRID:AB_354735, R&D Systems, AF1320, 1:100), E-cadherin (RRID:AB_477600 ...
• Enhanced Production of Mesencephalic Dopaminergic Neurons from Lineage-Restricted Human Undifferentiated Stem Cells

  Muyesier Maimaitili, et al., bioRxiv - Neuroscience 2021

  Quote: ... sheep anti-hCOL1A1 (1:200, R&D Systems), rabbit anti-hCOL3A1 (1:1000) ...
• MEKK3-TGFβ crosstalk regulates inward arterial remodeling

  Hanqiang Deng, et al., bioRxiv - Pathology 2021

  Quote: ... TGFβ (R&D Systems MAB1835; IHC 1:400), p-Smad2 Ser465/467 (Millipore AB3849-I ...
• MEKK3-TGFβ crosstalk regulates inward arterial remodeling

  Hanqiang Deng, et al., bioRxiv - Pathology 2021

  Quote: ... MEKK3 (R&D Systems MAB6095; IB 1:1000), MEKK2 (Abcam ab33918 ...
• Motor neurons involved in fine motor control are labeled by tracing Atoh1-lineage neurons in the spinal cord

  Osita W. Ogujiofor, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1:100 mouse anti-ERR3 (R&D Systems), 1:3000 alpha-bungarotoxin 488 (Invitrogen) ...
• Fatty acid binding proteins shape the cellular response to activation of the glucocorticoid receptor

  Bonan Liu, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... FABP3 (R&D Systems MAB1678; rabbit, 1:200), FABP4 (Abcam AB92501 ...
• DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas (PanNECs) and pancreatic neuroendocrine tumors (PanNETs)

  Tincy Simon, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PDX1 (1:100, R&D Systems, mouse, MAB2419)) and SOX9 (1:100 ...
• Parental-fetal interplay of immune genes leads to intrauterine growth restriction

  Gurman Kaur, et al., bioRxiv - Immunology 2021

  Quote: Mouse VEGF R1/Flt-1 (R&D systems), PIGF-2 (R&D systems ...
• Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment

  Virginie Mournetas, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and GLI3 (1/200, AF3690, R&D systems). Gels were rinsed once in water and blotted either with “high molecular weight” or “mixed molecular weight” program of TransBlot® Turbo™ transfer system (Bio-Rad ...
• Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment

  Virginie Mournetas, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Semaphorin 6A (1/55, AF1146, R&D systems) and GLI3 (1/200 ...
• The H2A.J histone variant contributes to Interferon-Stimulated Gene expression in senescence by its weak interaction with H1 and the derepression of repeated DNA sequences

  Adèle Mangelinck, et al., bioRxiv - Genetics 2020

  Quote: ... anti-IL1α(R&D Systems, MAB200, 1:200), anti-IL6 (R&D Systems ...
• p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

  Chrysa Kapeni, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Gata3 (goat polyclonal, 1:200, R&D Systems), CD34 (FITC RAM34 ...
• Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

  Odessa R. Yabut, et al., bioRxiv - Cancer Biology 2021

  Quote: ... goat anti-Gli2 (1:1000; R&D Systems), rabbit anti-Gli3 (1:100 ...
• PDFGRα⁺ Stromal Cells Promote Salivary Gland Proacinar Differentiation Through FGF2-dependent BMP7 Signaling

  Nicholas Moskwa, et al., bioRxiv - Developmental Biology 2021

  Quote: ... PDGFRα (1:100; R&D Systems #AF1062-SP), PDGFRβ (1:200 ...
• H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion by activating TRNP1 expression

  Cemil Kerimoglu, et al., bioRxiv - Developmental Biology 2021

  Quote: ... SOX2 mouse mAb (1:100; R&D Systems), SOX2 goat (1:100 ...
• Hyperoxia Inhibits the Growth of Mouse Forebrain Oligodendrocyte Progenitors

  Lisamarie Moore, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 1 ng/mL TGFß1 (R&D Systems) [30] for 5 – 7 days[LMM1] ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Sox17 (1:200; R&D Systems), rabbit anti-Foxa2 (1:1000 ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Brachyury (1:200; R&D Systems), rabbit anti-Tbr2 (1:500 ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Brachyury (1:200; R&D Systems), goat anti-NCAM (1:200 ...
• Single-cell landscapes of primary glioblastomas and matched organoids and cell lines reveal variable retention of inter- and intra-tumor heterogeneity

  VG LeBlanc, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Mouse anti-Sox2 (R&D Systems; 1:100), Goat anti-PDGFRa (R&D Systems ...