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1451 - 1500 of 10000+ citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• Deconstructing cold-induced brown adipocyte neogenesis in mice

  Rayanne B. Burl, et al., bioRxiv - Cell Biology 2022

  Quote: ... GPNMB (goat, 1:400; R&D Systems); I-A/I-E Alexa Fluor® 647 (MHCII ...
• NADPH oxidase promotes glioblastoma radiation resistance in a PTEN-dependent manner

  Kirsten Ludwig, et al., bioRxiv - Cancer Biology 2022

  Quote: ... NOX4 (1:100, R&D systems, MAB8158), and CYBA/P22 (1:100 ...
• YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER

  Sylvain Lefort, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CAIX (R&D Systems; 1/200; AF2188), CD34 (Abcam ...
• PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

  Lufei Sui, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Foxp3 (1:200; R&D Systems, MAB8214). After washing ...
• Microbiota–modulated enteric neuron translational profiling uncovers a CART+ glucoregulatory subset

  Paul A Muller, et al., bioRxiv - Neuroscience 2020

  Quote: ... CART (1:500, R&D Systems, AF163), CD9 (AF647 ...
• Aberrant induction of p19^Arf-mediated cellular senescence contributes to neurodevelopmental defects

  Muriel Rhinn, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Sox1 (1:50, R&D systems #AF3369); βIII-tubulin/Tuj1 (1:200 ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... IGF2 (R&D Systems, AF792, 1:1,000), and Ki67 (Thermo Fisher Scientific ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... ASCL1 (R&D Systems, BAF2567, 1:500), ERK1/2 (Cell Signaling ...
• Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosis

  Jennifer A Hollywood, et al., bioRxiv - Physiology 2021

  Quote: ... CD206 (1:100) (AF2534, R&D systems) in the blocking solution overnight at 4°C in a humidified chamber ...
• LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells

  Bo-Ruei Chen, et al., bioRxiv - Cell Biology 2021

  Quote: ... FANCD2 (R&D Systems, MAB93691, 1:1000), BRCA2 for human (Proteintech ...
• Cancer cells induce hepatocytes apoptosis in co-opted colorectal cancer liver metastatic lesions

  Miran Rada, et al., bioRxiv - Cancer Biology 2021

  Quote: ... elastase 1:250 (R&D Systems, #MAB91671).
• A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

  Lindsay B Alcaraz, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Recombinant SPARC (1 µM; R&D Systems) was incubated with self-activated pseudo-cath-D (5 nM ...
• Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

  Siyeon Rhee, et al., bioRxiv - Developmental Biology 2020

  Quote: ... hPROX1 (R&D Systems, AF2727, 1:250), NKX2.5 (Santa Cruz ...
• Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

  Siyeon Rhee, et al., bioRxiv - Developmental Biology 2020

  Quote: ... hPROX1 (R&D Systems, AF2727, 1:250). Secondary antibodies were Alexa Fluor conjugates (488 ...
• Adult fibroblasts retain organ-specific transcriptomic identity

  Elvira Forte, et al., bioRxiv - Cell Biology 2021

  Quote: ... HHEX (MAB83771, R&D System, 1:100), FOXD1 (TA322737 ...
• Detailed analysis of public RNAseq data and long non-coding RNA: a proposed enhancement to mesenchymal stem cell characterisation

  Sebastien Riquier, et al., bioRxiv - Genomics 2020

  Quote: ... 1 ng/mL FGF2 (R&D Systems), 2 mM L-glutamine ...
• Defining the structure, signals, and cellular elements of the gastric mesenchymal niche

  Elisa Manieri, et al., bioRxiv - Cell Biology 2023

  Quote: ... PDGFRA (R&D Systems, AF1062, 1:100); MUC5AC (Cell Signaling Technology ...
• Transgenic Mouse Models Establish a Protective Role of Type 1 IFN Response in SARS-CoV-2 infection-related Immunopathology

  Nishant Ranjan Chauhan, et al., bioRxiv - Immunology 2022

  Quote: ... ACE2 (R&D systems #AF933; 1:1000). HRP conjugated secondary antibodies were purchased from Promega (1:5000 ...
• Accurate quantification of lysyl oxidase concentration in human tissue

  Yimin Yao, et al., bioRxiv - Molecular Biology 2023

  Quote: ... LOXL2 (R&D Systems, AF2639, 1:500), rabbit anti-human LOXL4 (provided by Fernando Rodriguez-Pascual ...
• Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis

  Benjamin L.L. Clayton, et al., bioRxiv - Neuroscience 2023

  Quote: SOX10 (1:200, R&D Systems, AF2864)
• Morphodynamics of human early brain organoid development

  Akanksha Jain, et al., bioRxiv - Developmental Biology 2023

  Quote: ... CDH2 (1:100, R&D Systems, AF6426), COL4A1 (1:25 ...
• Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration

  Giovanni S. Offeddu, et al., bioRxiv - Bioengineering 2023

  Quote: ... COL-1 (#AF6220-SP, R&D Systems), ZO-1 (#33-9100 ...
• WFIKKN2 is a bifunctional axon guidance cue that signals through divergent DCC family receptors

  Kelsey R. Nickerson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and TrkC (R&D Systems, 1:200), rabbit polyclonal antibodies against TuJ1 (Biolegend ...
• Non-canonical function of folate/folate receptor 1 during neural tube formation

  Olga A. Balashova, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1:200 (R&D Systems, cat. # AF2018), anti-α-tubulin ...
• Non-canonical function of folate/folate receptor 1 during neural tube formation

  Olga A. Balashova, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1:300 (Cat # AF2018, R&D Systems), anti-α-tubulin ...
• Non-canonical function of folate/folate receptor 1 during neural tube formation

  Olga A. Balashova, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1:200 (R&D Systems, cat. # AF2018); pan-cadherin ...
• Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution

  Nicolò Caporale, et al., bioRxiv - Neuroscience 2023

  Quote: ... SOX2 (Goat, 1:1000, R&D System). The day after ...
• A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury

  Aleksandra Boikova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and IWR1 (1 µM, R&D Systems) for 48 hours and was refreshed for a further 48 hours ...
• The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

  Yanqiu Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... cisplatin (R&D systems, #15663-27-1), propidium iodide (PI ...
• The salt-and-pepper pattern in mouse blastocysts is compatible with signalling beyond the nearest neighbours

  Sabine C. Fischer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-GATA6 (R&D Systems, 1:200) They were rinsed three time in blocking buffer for 15 minutes each and incubated in secondary antibody solution for 1 hour in the dark ...
• Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

  Laura M. Pikkupeura, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Sox17 (R&D systems #AF1924, 1:300) and Gata4 (Santa Cruz #sc-25310 ...
• NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

  Abrar Choudhury, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD34 (AF7227, R&D Systems, 1:200), or NOTCH3/N3ECD as described above were used with overnight incubation at room temperature at 1:200 dilutions in TBS++++ ...
• Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids

  Davide Capauto, et al., bioRxiv - Genomics 2023

  Quote: ... SOX1 (goat, 1:100, R&D Systems), CTIP2 (rat ...
• Liver-specification of human iPSC-derived endothelial cells transplanted into mouse liver

  Kiryu K. Yap, et al., bioRxiv - Cell Biology 2023

  Quote: ... PDGFRβ (1:100, AF385, R&D Systems), glutamine synthetase (1:200 ...
• Dysregulation of mTOR Signaling Mediates Common Neurite and Migration Defects in Both Idiopathic and 16p11.2 Deletion Autism Neural Precursor Cells

  Smrithi Prem, et al., bioRxiv - Neuroscience 2022

  Quote: ... O4 (R&D Systems, MAB1326 1:500), GalC (Santa Cruz 1:250 sc-518055) ...
• Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: functional regulation of LDLR levels

  Carole Fruchart Gaillard, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-hLDLR (1:1,000; R&D system), anti-hPCSK9 (1:2,000 ...
• Slow integrin-dependent migration organizes networks of tissue-resident mast cells

  Sarah K. Bambach, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Mcpt6 (1:600, R&D Systems), anti-MITF (1:100 ...
• Nociceptive neurons interact directly with gastric cancer cells via a CGRP/Ramp1 axis to promote tumor progression

  Xiaofei Zhi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Cd31 (1:200, R&D Systems), anti-Tubb3 (1:200 ...
• Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine

  Judith M. Reyes Ballista, et al., bioRxiv - Microbiology 2024

  Quote: ... AXL (1:100, AF154, R&D Systems), GAPDH (1:2000 ...
• Lesion-remote astrocytes govern microglia-mediated white matter repair

  Sarah McCallum, et al., bioRxiv - Neuroscience 2024

  Quote: ... Sheep-TREM2 (1:250, R&D systems), Rabbit-YAP1 (1:200 ...
• Lesion-remote astrocytes govern microglia-mediated white matter repair

  Sarah McCallum, et al., bioRxiv - Neuroscience 2024

  Quote: ... Goat-SOX9 (1:200, R&D system), Mouse-SMI32 (1:3000 ...
• SARS-COV-2 induces blood-brain barrier and choroid plexus barrier impairments and vascular inflammation in mice

  Haowen Qiao, et al., bioRxiv - Neuroscience 2024

  Quote: ... CD13 (1:200; R&D System: AF2335); IBA1 (1:800 ...
• Brd4::Nutm1 fusion gene initiates NUT carcinoma in vivo

  Dejin Zheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... SOX2 (1:1000, R&D Systems, AF2018), TP63 (1:1000 ...
• NEUROG2 regulates a human-specific neurodevelopmental gene regulatory program

  Vorapin Chinchalongporn, et al., bioRxiv - Developmental Biology 2024

  Quote: ... NESTIN (1:500, R&D Systems #MAB1259), DCX (1:500 ...
• Targeting EIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer

  Na Zhao, et al., bioRxiv - Cancer Biology 2023

  Quote: ... S100A8 (1:5000, R&D Systems #MAB3059), BrdU (1:1000 ...
• Schistosoma mansoni cercarial invadolysin cleaves complement C3 and suppresses proinflammatory cytokine production

  Jacob R. Hambrook, Patrick C. Hanington, bioRxiv - Immunology 2022

  Quote: Recombinant human Eotaxin-1 (R&D systems) and recombinant IL-5 (R&D systems ...
• Periostin⁺ stromal cells guide lymphovascular invasion by cancer cells

  Jamie L. Null, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Pdpn (R&D Systems AF3244, 1:200). Antibodies were diluted in blocking buffer with 5% BSA ...
• Self-organized anteroposterior regionalization of early midbrain and hindbrain using micropatterned human embryonic stem cells

  Tianfa Xie, et al., bioRxiv - Bioengineering 2022

  Quote: ... OTX2 (goat, R&D Systems, 1:100), and PAX6 antibodies (mouse ...
• TET1 potentiates human iPS cell reprogramming by rectifying extraembryonic gene noises

  Makoto Motono, et al., bioRxiv - Cell Biology 2022

  Quote: ... and FOXA2 (1:500; R&D Systems). Alexa FluorTM-conjugated antibodies (1:500 ...
• Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration

  Benjamin Ng, et al., bioRxiv - Immunology 2022

  Quote: ... Podoplanin (R&D Systems, AF3244, 1:200), IL11 (Invitrogen ...