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1201 - 1250 of 3428 citations for 3 1 3 Dioxan 2 yl 3' methoxypropiophenone since 2020

• Patient-derived tumoroids of advanced high-grade neuroendocrine neoplasms mimic patient chemotherapy responses and guide the design of personalized combination therapies

  Simon L. April-Monn, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ARX (1:1500, R&D Systems, AF7068), PDX1 (1:100 ...
• ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

  Alexandre Jourdon, et al., bioRxiv - Neuroscience 2023

  Quote: ... SOX1 (goat, 1:100, R&D Systems), TBR1 (rabbit ...
• Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cells

  Kevin W. Southerland, et al., bioRxiv - Genomics 2023

  Quote: ... IGF-1 (R&D systems, 791-MG), FGF2 (Thermo Fisher ...
• A transient dermal niche and dual epidermal programs underlie sweat gland development

  Heather L. Dingwall, et al., bioRxiv - Developmental Biology 2023

  Quote: ... EDAR (1:100, R&D Systems AF745), PDGFRA (1:100 ...
• A transient dermal niche and dual epidermal programs underlie sweat gland development

  Heather L. Dingwall, et al., bioRxiv - Developmental Biology 2023

  Quote: ... PDGFRA (1:100, R&D Systems AF1062), and GFP (1:1000 ...
• Deep Visual Proteomics advances human colon organoid models by revealing a switch to an in vivo-like phenotype upon xenotransplantation

  Frederik Post, et al., bioRxiv - Cell Biology 2024

  Quote: ... Lrig1 (R&D Systems AF3688, 1:50), PDGFR (EPR22059-270 ...
• Stepwise developmental mimicry generates proximal-biased kidney organoids

  Jack Schnell, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PAX2 (R&D Systems, AF3364, 1:50), SIX1 (Cell Signaling Technology ...
• Stepwise developmental mimicry generates proximal-biased kidney organoids

  Jack Schnell, et al., bioRxiv - Developmental Biology 2024

  Quote: ... HAVCR1 (R&D Systems, AF1750, 1:200), γH2AX (Cell Signaling Technology ...
• Stepwise developmental mimicry generates proximal-biased kidney organoids

  Jack Schnell, et al., bioRxiv - Developmental Biology 2024

  Quote: ... JAG1 (R&D Systems, AF599, 1:300), HNF1B (Thermo Fisher Scientific ...
• Stepwise developmental mimicry generates proximal-biased kidney organoids

  Jack Schnell, et al., bioRxiv - Developmental Biology 2024

  Quote: ... HNF4A (R&D Systems, MAB4605, 1:200), CDH1 (BD Biosciences ...
• A foundational atlas of autism protein interactions reveals molecular convergence

  Belinda Wang, et al., bioRxiv - Systems Biology 2024

  Quote: ... FOXP2 (R&D Systems #AF5647 1:500), FOXG1 (Abcam #ab18259 1:1000) ...
• The gag-like gene RTL8 antagonizes PEG10-mediated virus like particles

  Will Campodonico, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1% L-glutamine (R&D Systems, Inc.), and 10% FBS (Millipore Sigma) ...
• Focused ultrasound enhanced antibody delivery for the treatment of Parkinson’s Disease

  Nancy Kwon, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:500 (R&D Systems; Minneapolis, MN), microglia with Iba-1 ...
• Elastase mediated white matter damage in cerebral small vessel disease: Microglia - neutrophils pas de deux

  Cheng-Ya Dong, et al., bioRxiv - Neuroscience 2024

  Quote: ... and Neuropilin-1 (AF566, R&D Systems). Samples were run on a FACSAria (BD Biosciences ...
• Influenza A virus-induced PI4P production at the endoplasmic reticulum involves ATG16L1 and promotes the egress of viral ribonucleoproteins

  Carla Alemany, et al., bioRxiv - Microbiology 2024

  Quote: ... CLIMP63 (R&D systems AF7355, 1:500), RNT3 (Santa Cruz sc-374599 ...
• Influenza A virus-induced PI4P production at the endoplasmic reticulum involves ATG16L1 and promotes the egress of viral ribonucleoproteins

  Carla Alemany, et al., bioRxiv - Microbiology 2024

  Quote: ... CLIMP63 (R&D systems AF7355, 1:500), ATG16L1 (MBL PM040 ...
• A central role for Numb/Nbl in multiple Shh-mediated axon repulsion processes

  Tiphaine Dolique, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Tag-1 (R&D Systems, AF4439) and anti-L1 (Chemicon MAB5272) ...
• DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects

  A Colomer-Boronat, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Sox17 (1:200, AF1924, R&D Systems) and Pax6 (1:200 ...
• mRNA stability fine tunes gene expression in the developing cortex to control neurogenesis

  Lucas D. Serdar, et al., bioRxiv - Neuroscience 2024

  Quote: ... RORβ (R&D Systems N7927, 1:100), LHX2 (Millipore ABE1402 ...
• G3BP1 Maintains Vascular Endothelial Barrier Integrity by Negatively Regulating the MYD88-ARNO-ARF6 Signaling Pathway

  Weiyue Sun, et al., bioRxiv - Physiology 2024

  Quote: ... CD31 (1: 100, AF3628; R&D system), G3BP1 (1:1000,13057-2-AP;Proteintech) ...
• Ablation of LRP6 in alpha-smooth muscle actin-expressing cells abrogates lung inflammation and fibrosis upon bleomycin-induced lung injury

  Eun-Ah Sung, et al., bioRxiv - Pathology 2024

  Quote: ... DKK1 (1:1500, AF1096, R&D Systems), IL-11 (1:1500 ...
• Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension

  Jose Gomez-Arroyo, et al., bioRxiv - Genomics 2024

  Quote: ... FOXF1 (1:50, AF4798, R&D Systems), ERG (1:100,AB92513 ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... R&D Systems)/Fibronectin (1 µg/mL; R&D Systems)-coated plates or coverslips ...
• Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans

  Xue Wen Ng, et al., bioRxiv - Cell Biology 2024

  Quote: ... glucagon (MAB1249; 1:100; R&D Systems) or somatostatin (MAB2358 ...
• Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

  Kaitlin P. McCreery, et al., bioRxiv - Cell Biology 2024

  Quote: ... SOX7 (R&D Systems, AF1924; 1:1000), YAP1 (Santa Cruz sc-101199 ...
• Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

  Jin Young Lee, et al., bioRxiv - Cancer Biology 2024

  Quote: ... FAP (1:200, R&D systems, AF3715). Images were captured using Zeiss Imager M1 or Leica Stellaris 5.
• Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

  Kaitlin P. McCreery, et al., bioRxiv - Cell Biology 2024

  Quote: ... SOX1 (R&D Systems, AF3369; 1:200), SOX7 (R&D Systems ...
• Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

  Kaitlin P. McCreery, et al., bioRxiv - Cell Biology 2024

  Quote: ... Brachyury (R&D Systems, AF2085; 1:1000), GATA6 (AF1700 ...
• Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans

  Xue Wen Ng, et al., bioRxiv - Cell Biology 2024

  Quote: ... glucagon (MAB1249; 1:100; R&D Systems) or somatostatin (MAB2358 ...
• Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors

  María A. Gómez-Muñoz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Nestin mouse (1:1000 R&D Systems), α-tubulin mouse (1:1000 Sigma) ...
• Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

  Rocío Hernández-Martínez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... or T(1:500 R&D systems), KDR (1:50 ...
• Tertiary lymphoid structures induced by CXCL13-producing CD4⁺ T cells increase tumor infiltrating CD8⁺ T cells and B cells in ovarian cancer

  Masayo Ukita, et al., bioRxiv - Immunology 2021

  Quote: ... Human T cells were also cultured under conditions where 5 µg/ml neutralizing anti-IL-2 antibody (R&D Systems, Minneapolis, MN, USA) or 10 ng/ml IL-12 (PeproTech ...
• Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

  José Alexandre Salerno, et al., bioRxiv - Cell Biology 2021

  Quote: ... IL-8 and TNF-α were quantified in the supernatants from uninfected and SARS-CoV-2-infected hiPSC-CMs by ELISA (R&D Systems), following manufacturer’s instructions ...
• Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

  Michael T. Meister, et al., bioRxiv - Cancer Biology 2022

  Quote: ... culture medium was supplemented with 0.1 to 0.5 % BME (Cultrex Reduced Growth Factor Basement Membrane Extract, type 2, Pathclear, R&D Systems, 3533-005-02). We observed batch-to-batch variations of this product ...
• SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly

  Anna Onnis, et al., bioRxiv - Immunology 2022

  Quote: ... were incubated for 30 min at 20°C in 50 μl RPMI-HEPES in the absence of BCS with 2 μg/ml anti-ACE2 antibody (R&D Systems, #AF933) (Hoffmann et al. ...
• The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension

  Anastasia Gorelova, et al., bioRxiv - Cell Biology 2022

  Quote: ... Samples were blocked in 2% goat serum for 45 mins at room temperature and incubated with anti-Snail (R&D Systems, Minneapolis, MN), anti-Zeb1 (Invitrogen ...
• A novel anti-inflammatory treatment for bradykinin-induced sore throat or pharyngitis

  Victor Leyva-Grado, Pavel Pugach, Nazlie Latefi, bioRxiv - Immunology 2021

  Quote: ... Cyclooxygenase-2-derived prostaglandin E2 (PGE2) and LTB4 release were measured with enzyme-linked immunosorbent assay kits (ELISA; R&D systems, Minneapolis, MN) according to the manufacturer’s instructions ...
• Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer’s disease pathology

  Zhengrong Zhang, et al., bioRxiv - Neuroscience 2021

  Quote: ... 2) anti-CD31 antibodies (#550274, BD Biosciences, San Jose, CA, USA; #ab28364, Abcam, Cambridge, MA, USA; #BBA7, R&D systems, Minneapolis, MN, USA); 3 ...
• A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

  Tanya Grancharova, et al., bioRxiv - Cell Biology 2021

  Quote: ... Media was replaced after 48 hours (Day 2) with RPMI-1640 supplemented with B27 without insulin and 5 µM IWP2 (R&D Systems #3533). Media was again replaced after an additional 48 hours (Day 4 ...
• Mammalian cells internalize bacteriophages and utilize them as a food source to enhance cellular growth and survival

  Marion C. Bichet, et al., bioRxiv - Microbiology 2023

  Quote: ... Murine IP-10 production was measured from 100 μL of the supernatant from the BMDMs using Mouse CXCL10/IP-10/CRG-2 Duo Set ELISA (R&D systems, #Dy466) according to the manufacturer’s protocol.
• Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors

  Jan Silhan, et al., bioRxiv - Biophysics 2023

  Quote: ... and rTv20S-inhibitor complex were diluted with 50 mM HEPES pH 7.5 then mixed with 2 μM MV151 (R&D Systems #I-190). After MV151 addition ...
• Small fibre neuropathy in Fabry disease: a human-derived neuronal in vitro disease model

  Thomas Klein, et al., bioRxiv - Neuroscience 2023

  Quote: ... ectodermal paired box 6 and SRY-box transcription factor 2 (PAX6/SOX2, Biolegend, San Diego, CA, USA / R&D Systems, Minneapolis, MN, USA), and forkhead box protein A2 (FOXA2 ...
• Inhibitory input directs astrocyte morphogenesis through glial GABA_BR

  Yi-Ting Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3mg of nuclear lysates were used for IP with 2 μg IgG or 5 μg primary antibodies (normal mouse IgG, Santa Cruz Biotechnology, sc-2025; normal rabbit IgG, R&D Systems, AB-105-C ...
• APOE Expression and Secretion are Modulated by Mitochondrial Dysfunction

  Meghan E. Wynne, et al., bioRxiv - Cell Biology 2022

  Quote: ... viability was measured with the BioTek Synergy HT plate reader using Gen5 software after a 2 hour incubation in Alamar blue (R&D Systems, AR002). Wells without cells and incubated in Alamar blue were used as a background reading.
• A multiadjuvant polysaccharide-amino acid-lipid (PAL) subunit nanovaccine generates robust systemic and lung-specific mucosal immune responses against SARS-CoV-2 in mice

  Bhawana Pandey, et al., bioRxiv - Bioengineering 2023

  Quote: ... Plates were incubated with PBSTBA diluted 500 ng/mL (25 ng/well) recombinant biotinylated human ACE-2 (R&D Systems, Cat# BT933-020) for 2 h at RT ...
• CCR9 signal termination is governed by an arrestin-independent phosphorylation mechanism

  Thomas D. Lamme, et al., bioRxiv - Biochemistry 2024

  Quote: ... cells were washed twice with cold FACS buffer and consequently incubated with anti-mouse F(ab)2 IgG (H+L) PE-conjugated antibody (R&D systems, F0102B) for 1h in the dark at 4 °C ...
• Generating human parvalbumin interneurons through 3D glia reprogramming

  Christina-Anastasia Stamouli, et al., bioRxiv - Neuroscience 2024

  Quote: ... small molecules (CHIR99021[2 mM, Axon, Groningen, Netherlands]; SB-431542[10 mM, Axon, Groningen, Netherlands]; noggin[0.5 mg/ml, R&D Systems R&D Systems, Minneapolis ...
• TGF-β induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis

  Zhenghan Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cells were cultured in media containing 2% FBS and treated with recombinant human Wnt-3a protein (R&D systems, Cat# 5036-WN-010) at a final concentration of 200ng/mL for 2h.
• TGF-β induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis

  Zhenghan Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 10 IU/ml of penicillin/streptomycin) containing 1,000 U/ml of murine recombinant IL-2 (R&D Systems, Cat# 402-ML-020).
• HIF-stabilization prevents delayed fracture healing

  Annemarie Lang, et al., bioRxiv - Bioengineering 2020

  Quote: For immunofluorescence staining the following primary antibodies: CD31/PECAM-1 (goat polyclonal unconjugated, AF2628, R&D Systems, 1:100), Emcn (V.7C7 unconjugated ...