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5401 - 5450 of 10000+ citations for D Iditol 1 13C since 2020

• Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells

  Linda V. Sinclair, et al., bioRxiv - Immunology 2024

  Quote: ... IL-12 + IL-18 (20ng/ml; R&D Systems) or no cytokine for 24h ...
• Monitoring macrophage polarization with gene expression reporters and bioluminescence phasor analysis

  Giulia Tedeschi, et al., bioRxiv - Bioengineering 2024

  Quote: ... and IL-13 (20 ng/mL, R&D Systems). After 18–24 h incubation ...
• Inhibition of EGFR/ErbB does not protect against C. difficile toxin B

  Uswah Siddiqi, et al., bioRxiv - Microbiology 2024

  Quote: ... and anti-TcdB sheep polyclonal antibody (R&D Systems) were used with species-specific secondary antibodies (Fisher Scientific).
• Engineered Ubiquitin Variants Mitigate Pathogenic Bacterial Ubiquitin Ligase Function

  Bradley E. Dubrule, et al., bioRxiv - Microbiology 2024

  Quote: ... 1.8 µg of HA-ubiquitin (all R&D Systems), His-ΔDiGly ...
• Chlamydia-driven ISG15 expression dampens the immune response of epithelial cells independently of ISGylation

  Yongzheng Wu, et al., bioRxiv - Microbiology 2024

  Quote: ... Recombinant human ISG15 (R&D systems, #UL-601-500) resuspended in culture medium served as a positive control in this experiment.
• Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

  Arthur Wickenhagen, et al., bioRxiv - Microbiology 2024

  Quote: ... SARS-CoV-2 spike S2 (MAB10557, R&D systems), VSV-M[23H12] (Ab01404-2.0 ...
• Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles

  Xu Zheng, et al., bioRxiv - Immunology 2024

  Quote: ... according to the manufacturer’s instructions (R&D Systems, DY201). RhoA pull-down activation assay Biochem Kit (BK036-S ...
• CD4-mediated immunity shapes neutrophil-driven tuberculous pathology

  Benjamin H Gern, et al., bioRxiv - Immunology 2024

  Quote: ... CXCL2 CF555 [conjugated in house] (polyclonal; R&D Systems), FoxP3 AF700 (clone FJK-16s ...
• A Membrane Lipid Signature Unravels the Dynamic Landscape of Group 1 ILCs

  Halle C. Frey, et al., bioRxiv - Immunology 2024

  Quote: ... plus 25 ng/ml IL-18 (R&D Systems) or 5 ng/ml IL-12 (Peprotech ...
• BRWD1 establishes epigenetic states for germinal center initiation, maintenance, and function

  Nathaniel E. Wright, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/ml IL-4 (R&D Systems) were added to the media.
• Proinflammatory cytokine-induced alpha-cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism

  Kristine Henriksen, et al., bioRxiv - Cell Biology 2024

  Quote: ... and recombinant human TNF-α (R&D Systems, USA) in a 1:5:5 ratio ...
• Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during cell growth arrest

  Francesco Neri, et al., bioRxiv - Cell Biology 2024

  Quote: ... and 100 µg/mL streptomycin (R&D Systems, B21210) at 37°C ...
• Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... EGF (100 ng/ml, R&D Systems, #236-EG), B27 (1x ...
• Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... EGF (100 ng/ml, R&D Systems, #236-EG), CHIR99021 (2 μM ...
• Vimentin regulates mitochondrial ROS production and inflammatory responses of neutrophils

  Thao Ngoc Huynh, et al., bioRxiv - Immunology 2024

  Quote: ... Matrix metalloprotease 9 (MMP-9) (R&D Systems, DY6718), and IL-1β (R&D Systems ...
• Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Response

  Naseeb Kaur Malhi, et al., bioRxiv - Cell Biology 2024

  Quote: ... or rat IgG isotype control (R&D systems; MAB0061)
• Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson’s disease

  Amalie Holm Nygaard, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PDGFC 1ug/ml (R&D Systems, #1687-CC-025) or NT-3 10-20ng/ml (R&D Systems ...
• Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

  Javier Abello, et al., bioRxiv - Developmental Biology 2024

  Quote: ... FGF (R&D systems, Cat.#: 233-FB-025/CF), SCF (R&D systems ...
• Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

  Javier Abello, et al., bioRxiv - Developmental Biology 2024

  Quote: ... IL3 (R&D systems, Cat.#: 203-IL-010/CF), SDF1a (Cat.# ...
• Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

  Javier Abello, et al., bioRxiv - Developmental Biology 2024

  Quote: ... FGF (R&D systems, Cat.#: 233-FB-025/CF), and IGF-2 (R&D systems Cat.# ...
• Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

  Javier Abello, et al., bioRxiv - Developmental Biology 2024

  Quote: ... SCF (R&D systems, Cat.#: 255-SC-010/CF), IL3 (R&D systems ...
• Stress granule induction in rat retinas damaged by constant LED light

  María M. Benedetto, et al., bioRxiv - Cell Biology 2024

  Quote: ... 0.02% (v/v) Recombinant Human BDNF (R&D Systems), 2% (v/v ...
• Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Promote Establishment and Maintenance of the Legionella Replication Vacuole

  Kristin M. Kotewicz, et al., bioRxiv - Microbiology 2024

  Quote: ... or K48-linked (R&D Systems, Cat# UC-220) poly-ubiquitin and 500μM ε-NAD in 300 μl of 1X ART buffer for 2 hrs with end-over-end gentle rotation at 37°C ...
• Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Promote Establishment and Maintenance of the Legionella Replication Vacuole

  Kristin M. Kotewicz, et al., bioRxiv - Microbiology 2024

  Quote: ... or monomeric Ub (R&D Systems, Cat# U-100H) were incubated together with 100 μM β-NAD and 20 nM SdeC variants (WT ...
• Systemic inflammation modulates the levels of EBI2 and 7α,25-OHC synthesizing (CH25H, CYP7B1) and degrading (HSD3B7) enzymes in brain microvascular cells

  Fionä Caratis, et al., bioRxiv - Neuroscience 2024

  Quote: ... goat polyclonal PDGFRβ (RRID: AB_2162633, AF1042, R&D Systems), rabbit monoclonal PDGFRβ (RRID ...
• Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... EGF (100 ng/ml, R&D Systems, #236-EG), CHIR99021 (2 μM ...
• Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Response

  Naseeb Kaur Malhi, et al., bioRxiv - Cell Biology 2024

  Quote: ... Intramuscular injections of TREM2-Ab (R&D systems; MAB17291) or rat IgG isotype control (R&D systems ...
• Systematic perturbation screens decode regulators of inflammatory macrophage states and identify a role for TNF mRNA m6A modification

  Simone M Haag, et al., bioRxiv - Immunology 2024

  Quote: ... 100 ng/mL Noggin (R&D Systems, 6057-NG), 500 nM A83-01 (Tocris ...
• 3D patterns in alginate hydrogel degradation spatially guide YAP nuclear translocation and hMSC osteogenic differentiation

  Claudia A. Garrido, et al., bioRxiv - Bioengineering 2024

  Quote: ... and OCN Monoclonal Mouse IgG1 (R&D Systems, #MAB1419) at 25 µg/mL in PBS ...
• Engineered CRISPR-Base Editors as a Permanent Treatment for Familial Dysautonomia

  Shuqi Yun, et al., bioRxiv - Bioengineering 2024

  Quote: ... 25 ng/ml BDNF (R&D Systems, 248- BD), 200 uM Ascorbic Acid (Sigma ...
• Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

  Nevin K. Zacharia, et al., bioRxiv - Biochemistry 2024

  Quote: ... 5 μM ubiquitin (R&D Systems #U-100H-10M) and 2 μM His-TEV-HsIFT172C1 ...
• A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

  Hyo Jun Kwon, Devi Santhosh, Zhen Huang, bioRxiv - Neuroscience 2024

  Quote: ... goat anti-MMP2 (R&D Systems; 5 μg/ml), rabbit anti-Calretinin (Chemicon ...
• An Alzheimer’s disease-associated common regulatory variant in a PTK2B intron alters microglial function

  Erica Bello, et al., bioRxiv - Neuroscience 2024

  Quote: ... and 25 ng/ml rhIL-3 (R&D Systems). Macrophage precursor cells could be routinely harvested from dishes containing EBs every 6/7 days for up to 3/4 months ...
• β-Amyloid impairs Proteasome structure and function. Proteasome activation mitigates amyloid induced toxicity and cognitive deficits

  Kanisa Davidson, et al., bioRxiv - Molecular Biology 2024

  Quote: Purified 20S Proteasome (R&D Systems, Cat# E-360), purified 26S Proteasome (R&D Systems ...
• β-Amyloid impairs Proteasome structure and function. Proteasome activation mitigates amyloid induced toxicity and cognitive deficits

  Kanisa Davidson, et al., bioRxiv - Molecular Biology 2024

  Quote: ... purified 26S Proteasome (R&D Systems, Cat# E-365). TAT1-TOD and TAT1-DEN were generated as described in out prior study (30 ...
• The neonatal Fc receptor and DPP4 are human astrovirus receptors

  Harshad Ingle, et al., bioRxiv - Microbiology 2024

  Quote: ... or human DPP4/CD26 antibody (R&D Systems; AF1180) 12h prior to HAstV infection ...
• A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics

  Kuan-Yi Lu, et al., bioRxiv - Microbiology 2024

  Quote: ... 10% (vol/vol) heat-inactivated FBS (R&D Systems) and 20% conditioned medium.
• Assembloid model to study loop circuits of the human nervous system

  Yuki Miura, et al., bioRxiv - Neuroscience 2024

  Quote: ... and SB-431542 (10 μM, R&D Systems, 1614) and was changed every day ...
• Autophagic enhancer rescues Tau accumulation in a stem cell model of frontotemporal dementia

  Farzaneh S. Mirfakhar, et al., bioRxiv - Neuroscience 2024

  Quote: ... and laminin-coated (R&D Systems, 3400-010-03) plates to form neural rosettes ...
• IL-21 Shapes the B Cell Response in a Context-Dependent Manner

  Youngjun Kim, et al., bioRxiv - Immunology 2024

  Quote: ... or IL-21 (R&D Systems, 10 ng/mL) with fresh irradiated 40LB feeder cells ...
• Sulfatide deficiency-induced astrogliosis and myelin lipid dyshomeostasis are independent of Trem2-mediated microglial activation

  Namrata Mittra, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Serpina3N (goat, R&D systems, USA, Cat. #: AF4709), anti-Vimentin (chicken ...
• Sulfatide deficiency-induced astrogliosis and myelin lipid dyshomeostasis are independent of Trem2-mediated microglial activation

  Namrata Mittra, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Axl (goat, R&D systems, USA, Cat. #: AF854), and anti-β-actin (rabbit ...
• Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer’s Disease Revealed by Pharmacological and Genetic Microglial Depletion

  Ziying Xu, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-PGRN (sheep, R&D Systems, Minneapolis, MN, USA), anti-Phospho-PLA2G4A (Ser505 ...
• Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia

  Julian R. Buissant des Amorie, et al., bioRxiv - Cell Biology 2024

  Quote: ... recombinant human NRG1 (20 ng/ml, R&D systems), recombinant murine WNT5a (20 ng/ml ...
• Divergence in poxvirus-encoded E3-like proteins can dictate poxvirus activation of cellular necroptosis

  Junior A. Enow, et al., bioRxiv - Microbiology 2024

  Quote: ... mouse TNF-alpha (R&D Systems # AF-410-NA) and Z-NA ( Novus Biologicals # NB100-746)
• The food grade bacterium Lactobacillus helveticus VEL12193 promotes autophagy by releasing membrane vesicles

  Marie-Agnès Bringer, et al., bioRxiv - Microbiology 2024

  Quote: ... and Mouse IFN-beta DuoSet ELISA (R&D Systems) according to the manufacturers’ instructions.
• Presynapses are mitophagy pit stops that prevent axon degeneration

  Wai Kit Lam, et al., bioRxiv - Cell Biology 2024

  Quote: ... Sonic Hedgehog (200 ng/mL, R&D Systems; 1314SH) and laminin (1 μg/mL ...
• A repository of Ogden syndrome patient derived iPSC lines and isogenic pairs by X-chromosome screening and genome-editing

  Josephine Wesely, et al., bioRxiv - Genetics 2024

  Quote: Human iPSCs maintained on Cultrex (CTX, R&D Systems) in PSC Freedom Media (FRD1 ...
• Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells

  Elizabeth Elder, et al., bioRxiv - Cell Biology 2024

  Quote: ... APC-conjugated anti-Sheep IgG (R&D Systems, F0127) and Alexa Fluor™ 488-conjugated anti-Goat IgG (Thermo Fisher ...
• Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells

  Milad Rezvani, et al., bioRxiv - Developmental Biology 2024

  Quote: ... we applied 5 ng/ml FGF2 (R&D Systems), 20 ng/ml EGF (R&D Systems) ...