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4551 - 4600 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Multiomic deep delve of synthesis and secretion processes in a model peptidergic system

  Soledad Bárez-López, et al., bioRxiv - Neuroscience 2022

  Quote: ... with 0.1% (v/v) Tween 20 (TBS-T) for 1 hour followed by incubation with the primary antibodies NOS1 (1:200, Santa Cruz biotechnology, sc-5302), phospho-nNOS (Ser852 ...
• Neutrophil Extracellular Traps contribute to the pathogenesis of leprosy type 2 reactions

  Camila Oliveira da Silva, et al., bioRxiv - Immunology 2019

  Quote: ... rabbit polyclonal anti-MPO antibody (1:50 for in vitro immunofluorescence; 1:100 for tissue; catalog number sc-16128-R; Santa Cruz Biotechnology, CA, EUA), and mouse monoclonal anti-DNA/Histona H1 antibody (1:100 ...
• Expression of Separate Foreign Proteins from the Rotavirus NSP3 Genome Segment Using a Translational 2A Stop-Restart Element

  Asha A. Philip, John T. Patton, bioRxiv - Microbiology 2020

  Quote: ... The cells were then incubated with guinea pig NSP3 polyclonal antiserum (lot 55068; 1:500) or mouse PABP-specific monoclonal antibody (10E10, Santa Cruz Biotechnology; 1:100) in PBS containing 3% BSA for 1 h at room temperature (2) ...
• Association of NQO1 C609T (Pro187Ser) with risk of Oral Submucous Fibrosis in Eastern Indian population

  Sanjit Mukherjee, et al., bioRxiv - Genetics 2021

  Quote: ... and incubated with mouse monoclonal NQO1 (1:1000) (Cell Signalling Technology, Beverly, MA) and β-Actin Antibody (C4) (1:2000) (Santa Cruz Biotechnology, USA) as primary antibodies ...
• A transient role of primary cilia in controlling direct versus indirect neurogenesis in the developing cerebral cortex

  Kerstin Hasenpusch-Theil, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-ribosomal protein phospho-S6S240/S244 (1:1000, CST #2215) and mouse anti-ribosomal protein S6 (C-8) (1:1000, Santa Cruz Technologies #sc-74459). For the detection of phosphorylated proteins goat anti-rabbit IRDye 680RD (1:15,000 ...
• Asparagine hydroxylation is likely to be a reversible post-translational modification

  Javier Rodriguez, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-GFP and anti-myc were from Cell signalling (D5.1-9B11, 1:2,000 dilution,) anti-tubulin was purchased from Santa Cruz (sc-8035, 1:1,000 dilution) and anti-V5 was obtained from Invitrogen (R96025 ...
• Light affects behavioral despair involving the clock gene Period 1

  Iwona Olejniczak, et al., bioRxiv - Genetics 2020

  Quote: ... followed by 16 hours primary antibody incubation at 4 °C (rabbit anti-PER1 antibody produced by J. Ripperger, 1:1000; mouse anti-HSP90, 1:1000 (Santa Cruz Biotechnology, sc-13119); in 5% milk ...
• Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination

  Megan E. Rowland, et al., bioRxiv - Neuroscience 2022

  Quote: ... This was followed by incubation with the appropriate horseradish peroxidase–conjugated secondary antibody for 1 hour at room temperature: mouse anti-HRP (1:3,000, Santa Cruz Cat# sc-516102, RRID:AB_2687626), rabbit anti-HRP (1:5000 ...
• Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: functional regulation of LDLR levels

  Carole Fruchart Gaillard, et al., bioRxiv - Molecular Biology 2022

  Quote: ... samples were incubated at 4°C overnight with the respective primary antibodies (LDLR, R&D Systems, 1:200 and CAP1, Santa Cruz, 1:1,000). Cells were then washed with PBS and incubated with the appropriate fluorescent secondary antibody (all from Thermo Fisher ...
• Scalable, optically-responsive human neuromuscular junction model reveals convergent mechanisms of synaptic dysfunction in familial ALS

  Daniel Chen, et al., bioRxiv - Neuroscience 2024

  Quote: The primary antibodies used for myoblasts were mouse anti-myogenin (DSHB; 1:500 dilution) and rabbit anti-MyoD (Santa Cruz Biotechnology; 1:500 dilution). The primary antibodies used for skeletal muscles were mouse anti-MHC (DSHB ...
• SIK2: A novel negative feedback regulator of FGF signaling

  Gamze Kuser-Abali, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Takemori (National Institute of Biomedical Innovation, Osaka, Japan at 1:125 dilution) and anti-Gab1 antibody (Santa Cruz-H-198, at 1:25 dilution) were used ...
• Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer

  Esther Wortmann, et al., bioRxiv - Microbiology 2024

  Quote: ... dilution 1:400) followed by a second overnight incubation with the secondary antibody (Goat Anti-Rabbit IgG, Santa Cruz sc-2780, dilution 1:400). Peroxidase activity was detected using diaminobenzidine (DAB ...
• Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection

  Cason R. King, et al., bioRxiv - Microbiology 2023

  Quote: ... blocked with 1% BSA in PBS, incubated with primary antibodies anti-RNP (1:1000, BEI Resources Repository NR-3133) and anti-dsDNA (1:100, Santa Cruz Biotechnology sc-58749), and then secondary antibodies donkey anti-goat 488 AlexaFluor (Invitrogen ...
• AI-based antibody discovery platform identifies novel, diverse and pharmacologically active therapeutic antibodies against multiple SARS-CoV-2 strains

  Cristina Moldovan Loomis, et al., bioRxiv - Immunology 2023

  Quote: ... and allowed to incubate for 1 hour at RT before captured virions were detected using a 1:5000 dilution of anti-M13-HRP (Santa Cruz Biotechnology, Dallas, TX) for 1 hour at RT ...
• Caught in the Act: targeted mutagenesis of the herpesvirus fusogen central helix captures transition states

  Momei Zhou, et al., bioRxiv - Microbiology 2023

  Quote: ... and primary antibodies to cellular proteins were used as markers for early endosomes (EEA-1; rabbit polyclonal antibody; Santa Cruz Biotechnology Inc; 1:200), and the trans-Golgi (TGN46 ...
• Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth

  Ali Rashidfarrokhi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... for 60 minutes at room temperature and then incubated with the primary antibodies pSTAT3 (CST 9145, 1:1000) and GAPDH (Santa Cruz 25778, 1:4000) in 5% BSA overnight at 4°C ...
• DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor

  Ninoslav Pandiloski, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The following day the membrane was washed twice in TBST (15 min) and incubated (1 h, room temperature) with HRP-conjugated anti-mouse or anti-rabbit secondary antibody (Santa Cruz Biotechnology, 1:5,000) diluted in MTBST ...
• Structural mechanism of angiogenin activation by the ribosome

  Anna B. Loveland, et al., bioRxiv - Biochemistry 2023

  Quote: ... the membranes were incubated with primary antibody either 1:500 mouse anti-angiogenin monoclonal antibody C-1 (sc-74528, Santa Cruz Biotechnologies, Dallas, TX) or 1:500 mouse anti-ribosomal protein s5 monoclonal antibody (A-8 ...
• Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice

  Giada Lavigna, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... Sections were incubated at 4°C overnight with primary antibody rabbit anti-Calbindin D-28k (CB38, Swant, 1:2500) or rabbit poly-clonal anti GADD153/CHOP (sc-575, Santa Cruz Biothechnology, 1:250), diluted in blocking solution ...
• Sexually dimorphic phenotypes and the role of androgen receptors in UBE3A-dependent autism spectrum disorder

  Yuan Tian, Hui Qiao, Ling-Qiang Zhu, Heng-Ye Man, bioRxiv - Neuroscience 2024

  Quote: The following antibodies were used in the indicated dilution or amount: Mouse anti-AR (WB: 1:500; IF: 1:200; IP: 1.5 µg; Santa Cruz Biotechnology; Cat# sc-7305). Mouse anti-ERα (WB ...
• The tricellular junction protein ILDR2 in glomerulopathies: insights and implications

  Florian Siegerist, et al., bioRxiv - Cell Biology 2024

  Quote: ... and incubated with rabbit anti-podocin 1:150 (IBL International, Germany) and mouse anti-integrin α3 conjugated with Alexa Fluor 647 1:500 (Santa Cruz Biotechnology, Dallas, USA) and anti-rabbit Alexa Fluor 488-conjugated IgG 1:600 (ChromoTek ...
• Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

  H. Nayanga Thirimanne, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Rabbit c-Jun (1:25, Santa Cruz Cat #sc-1694), Rabbit anti-Myc (1:25 ...
• SMURF2 phosphorylation at Thr249 modifies the stemness and tumorigenicity of glioma stem cells by regulating TGF-β receptor stability

  Manami Hiraiwa, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-β-actin (#sc-47778, 1:2000) (Santa Cruz Biotechnology), anti-Sox4 (#AB5803 ...
• Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

  Andrea Sacchetti, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and ZEB1 (rabbit, 1:200; sc-25388, Santa Cruz Biotechnology). After washing twice with PBS-Tween ...
• NMNAT promotes glioma growth through regulating post-translational modifications of p53 to inhibit apoptosis

  Jiaqi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p53(E-5) (1:50, Santa Cruz, sc-74573), p53(DO-1 ...
• Tuba1a is uniquely important for axon guidance through midline commissural structures

  Georgia Buscaglia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and mouse anti-Map1b (Santa Cruz, sc-135978; 1:500). Blots were incubated in HRP-conjugated Goat-anti-mouse (1:5,000 ...
• Esrrγa regulates nephron development and ciliogenesis by controlling prostaglandin synthesis and cooperation with Ppargc1a

  Hannah M. Wesselman, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and used anti-aPKC diluted 1:500 (Santa Cruz 2300359) to mark apical surface and anti-Na+K+ ATPase diluted 1:35 (DSHB 528092 ...
• Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states

  Xueqing Chen, Mark M. Emerson, bioRxiv - Developmental Biology 2021

  Quote: ... mouse anti-Pan Brn3 (Sc-390781, Santa Cruz, 1:100), sheep anti-Vsx2 (x1180p ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-GAPDH (1: 10,000; Santa Cruz Biotechnology sc-25778) or mouse anti-GAPDH (1:10,000 ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-TRIP6 (1:1000; Santa Cruz Biotechnology sc-365122), rabbit anti-VASP (1:1000 ...
• TRAF6 controls spinogenesis instructing synapse density and neuronal activity through binding neuroplastin

  Sampath Kumar Vemula, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-RelA (p65) rabbit (Santa Cruz, #sc-372; 1:500); anti-MAP2 guinea pig (Synaptic Systems ...
• Phosphorylation of the Anaphase Promoting Complex activator CDH1/FZR regulates the transition from Meiosis I to Meiosis II in mouse male germ cell

  Nobuhiro Tanno, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-CyclinB1(IB, 1:1000, Santa Cruz: sc-595), mouse anti-PLK1(IB ...
• Htr6 and Sstr3 ciliary targeting relies on both IC3 loops and C-terminal tails

  Pablo Barbeito, et al., bioRxiv - Cell Biology 2020

  Quote: ... adenylyl cyclase III (Santa Cruz, C-20, IF: 1:100), B9D1 (Novus Biologicals ...
• Defining totipotency using criteria of increasing stringency

  Eszter Posfai, et al., bioRxiv - Cell Biology 2020

  Quote: ... goat anti-Oct4 1:100 (sc-8629, Santa Cruz Biotechnologies); goat anti-Sox17 1:100 (AF1924 ...
• SEMA3F-deficient colorectal cancer cells Promote lymphangiogenesis: fatty acid metabolism replace glycolysis for energy supply during lymphatic endothelial cells proliferation in tumor hypoxia microenvironment

  Xiaoyuan Fu, et al., bioRxiv - Cell Biology 2019

  Quote: ... FITC-conjugated goat anti-mouse IgG (1:50, Santa Cruz), or TRITC-conjugated goat anti-mouse IgG (1:50 ...
• mRNA translation control by Dhx36 binding to 5’UTR G-quadruplex structures is essential for skeletal muscle stem cell regenerative functions

  Xiaona Chen, et al., bioRxiv - Cell Biology 2020

  Quote: ... Primary antibodies used include: MyoD (1:100) (Santa Cruz Biotechnology) and Myogenin (1:200 ...
• BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

  Yun-Ling He, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-HA (1:1,000, rabbit pAb, Santa Cruz, sc-805), anti-PP1 (1:1,000 ...
• BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

  Yun-Ling He, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-GFP (1:1,000, rabbit pAb, Santa Cruz, sc-8334), anti-HA (1:1,000 ...
• BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

  Yun-Ling He, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-PP1 (1:1,000, mouse mAb, Santa Cruz, sc-7482), anti-TOMM20 (1:5,000 ...
• Pharmacological CDK4/6 inhibition unravels a p53-induced secretory phenotype in senescent cells

  Boshi Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... p53 (clone DO-1, cat# sc-126, Santa Cruz Biotechnology), Rb (clone 4H1 ...
• ER-embedded UBE2J1/RNF26 ubiquitylation complex in spatiotemporal control of the endolysosomal pathway

  Tom Cremer, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Ubiquitin (1:25, P4D1, sc-8017, Santa Cruz), rabbit anti-LAMP1 (1:200 ...
• Single cell transcriptomic analyses reveal the impact of bHLH factors ATOH7 and Neurog2 on human retinal organoid development

  Xiangmei Zhang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-Ngn2 (1:200; Santa Cruz Biotechnology, sc-19233); mouse anti-BrdU (1:1 ...
• Single cell transcriptomic analyses reveal the impact of bHLH factors ATOH7 and Neurog2 on human retinal organoid development

  Xiangmei Zhang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-BRN3a (1:100; Santa Cruz Biotechnology, sc-31984); goat anti-pan BRN3 (1:50 ...
• Galvanic current activates the NLRP3 inflammasome to promote type I collagen production in tendon

  Alejandro Peñín-Franch, et al., bioRxiv - Immunology 2021

  Quote: ... and anti-β-Actin mouse monoclonal (1:10000, Santa Cruz). Appropriate secondary antibody conjugated with HRP was used at 1:5000 dilution (Sigma ...
• Inhibition of the SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity

  Aviad Ben-Shmuel, et al., bioRxiv - Immunology 2021

  Quote: ... Rabbit anti-SHP-1 and Mouse anti-GAPDH (Santa Cruz), Rabbit anti-pSHP-1 (S591 ...
• PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet

  Xiaodun Yang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Onecut1 (Santa Cruz Biotechnology, H-100, 1:1000), and guinea-pig anti-Insulin (Abcam ...
• Extraembryonic endoderm cells induce neuroepithelial tissue in gastruloids

  Noémie M. L. P. Bérenger-Currias, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-T (1:200, sc-17745, Santa Cruz Biotechnology), mouse anti-N-cadherin (1:200 ...
• Extraembryonic endoderm cells induce neuroepithelial tissue in gastruloids

  Noémie M. L. P. Bérenger-Currias, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-T (1:200, sc-17745, Santa Cruz Biotechnology), goat anti-T (1:100 ...
• Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

  Chloé Mayère, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mouse anti-GATA4 (1:500, Sc-25310, Santa Cruz Biotechnology), goat anti-SOX9 (1:1000 ...
• Stabilization of spine Synaptopodin by mGluR1 is required for mGluR-LTD

  Luisa Speranza, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Synaptopodin (1/200; Santa Cruz Biotech, RRID: AB_2201166), rabbit mGluR1 (1/500 ...