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4451 - 4500 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• Chlamydial protease-like activating factor targets SLC7A11 for degradation to induce ferroptosis and facilitate dissemination

  Wentao Chen, et al., bioRxiv - Microbiology 2023

  Quote: ... TfR1(1:500, Santa Cruz Biotechnology Cat# sc-32272), Vimentin (1:1000 ...
• Identification of a P62-TIF-IA axis that drives nucleolar fusion and the senescence associated secretory phenotype

  Hazel C Thoms, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Actin-HRP (Mouse 1:2000 sc-47778 Santa Cruz). Bands were quantified using ImageJ as per software instructions.
• Torques within and outside the human spindle balance twist at anaphase

  Lila Neahring, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-MKLP1 C-12 (1:50, Santa Cruz Biotechnology sc-390113 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Arp2 (1:1000; Santa Cruz; sc-166103), mouse anti-Arp3 (1:1000 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-WIP1 (1:1000, Santa Cruz; sc-271113), rabbit anti-WIP2 (1:1000 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Arp3 (1:1000; Santa Cruz; sc-48344), mouse anti-MyoG (1:30 ...
• Analyzing ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

  Michelle E. Watts, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Chx10 (Santa Cruz Biotechnology sc-365519, 1:50), and anti-TUJ1 (Biolegend 801202 ...
• A novel iPSC model reveals selective vulnerability of neurons in Multiple Sulfatase Deficiency

  Vi Pham, et al., bioRxiv - Cell Biology 2023

  Quote: ... IgM isotype control (1:100, Santa Cruz, sc-3881). Cells were subsequently washed with saponin buffer or FACS buffer and incubated for 1 hr with secondary antibodies ...
• Revisiting the potency of Tbx2 expression in transforming outer hair cells into inner hair cells at multiple ages in vivo

  Zhenghong Bi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-Prestin (goat, 1:1000; sc-22692, Santa Cruz), anti-vGlut3 (rabbit ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-PIK3CG (1:500; sc-166365; Santa Cruz Biotechnology), anti-ubiquitin (1:1000 ...
• CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality

  Tanja Sack, et al., bioRxiv - Biochemistry 2023

  Quote: ... 1:1000 and anti-WRNIP1 (Santa Cruz, sc-377402). The cells were stained with MitoTracker Deep Red (200 nM ...
• Tubular obstruction induced polycystin upregulation is pro-fibrotic and induced a severe cystic phenotype in adult mice with autosomal dominant polycystic kidney disease: the coexistence of polycystin loss and gain function in ADPKD

  Ming Wu, et al., bioRxiv - Pathology 2023

  Quote: ... anti-N-cadherin (1:1000, sc-59887, Santa Cruz), anti-vimentin (1:1000 ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GFP (Santa Cruz Bio cat.no. sc-9996, 1:1,000). The following secondary antibodies were used ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Rad51 (Santa Cruz Bio cat.no. sc-8349, 1:1,000), PARP1 (Enzo Life Sciences cat ...
• The NAD⁺ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers’ Disease

  Yu Hong, et al., bioRxiv - Neuroscience 2023

  Quote: ... Nestin (1:50, Santa Cruz Biotechnology, cat. no. sc23927), NeuN (1:500 ...
• Long-chain fatty acyl-coenzyme A activates the mitochondrial fission factors MiD49 and MiD51 by inducing their oligomerization

  Ao Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (G-9, mouse; Santa Cruz Biotechnology; 1:500), actin (mouse ...
• Amyloid β induces cardiac dysfunction and neuro-signaling impairment in the heart of an Alzheimer’s disease model

  Andrea Elia, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and GAPDH (sc-32233,6C5; Santa Cruz Biotechnology; 1: 2000), the latter which was used as the loading control ...
• Influenza A virus NS1 effector domain is required for PA-X mediated host shutoff

  Juliette Bougon, et al., bioRxiv - Microbiology 2023

  Quote: ... NP (IAV) (1:1000, mouse, Santa Cruz, sc-101352), NP (IBV ...
• Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and function

  Bryan Alava, et al., bioRxiv - Neuroscience 2023

  Quote: ... Tau46 (Santa Cruz Biotechnology Inc. sc-32274; 1:1000), or AT8 primary antibody (Thermo Fisher Scientific MN1020 ...
• Collagen fibril formation at the plasma membrane occurs independently from collagen secretion

  Adam Pickard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Syntaxin 5 (Santa Cruz, sc-365124, 1:500(WB)) PDI (Abcam ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... WAPL (A-7, Santa Cruz, sc-365189, 1:1000), CHK1 (2G1D5 ...
• Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth

  Hitoshi Matakatsu, Richard G. Fehon, bioRxiv - Developmental Biology 2024

  Quote: ... Rabbit anti-HA (1:1,000; Y-11, Santa Cruz), iFluor 555 or iFluor 647 conjugated Mouse anti-V5 (1:100 ...
• Notch1 is required to maintain supporting cell identity and vestibular function during maturation of the mammalian balance organs

  Alison Heffer, et al., bioRxiv - Developmental Biology 2024

  Quote: ... anti-Spp1(OPN) (mouse, 1:300, Santa Cruz Biotechnology), anti-Calb2 (rabbit ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-EGFR (1:50, Santa Cruz sc-120), chicken anti-GFP (1:500 ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... RAD52 (F-7, Santa Cruz, sc-365341, 1:500), POLθ (Thermo Fisher Scientific ...
• A predominately pulmonary activation of complement in a mouse model of severe COVID-19

  Peter J. Szachowicz, et al., bioRxiv - Immunology 2024

  Quote: ... anti-HopE1 (1:100, cat#sc-398703, Santa Cruz), anti-vWF (1:500 ...
• The meninges host a unique compartment of regulatory T cells that bulwarks adult hippocampal neurogenesis

  Miguel Marin-Rodero, et al., bioRxiv - Immunology 2024

  Quote: ... goat anti-doublecortin (1:500, Santa Cruz, sc-8066); CLR ...
• Glial ferritin maintains neural stem cells via transporting iron required for self-renewal in Drosophila

  Zhixin Ma, et al., bioRxiv - Developmental Biology 2024

  Quote: ... mouse anti-aPKC (1/50, Santa Cruz, Sc-17781).
• Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

  Nelson García-Vázquez, et al., bioRxiv - Biochemistry 2024

  Quote: ... cyclin E (1:1,000, Santa Cruz Biotechnology sc-247), Flag (1:2,000 ...
• Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice

  Alejandro Martín-Ávila, et al., bioRxiv - Neuroscience 2024

  Quote: ... and TRIM21 (Ro/SSA) (1:1000, Santa Cruz, mouse) in Superblock TM blocking buffer in TBS (Thermo Fisher Scientific ...
• Hematopoietic growth factors Regulate Entry of Monocytes into the Adult Brain via Chemokine Receptor CCR5

  Xuefang Ren, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-GCSFR (1:100, Santa Cruz Biotechnology, USA), rat anti-CD31 (1:200 ...
• The UFMylation pathway is impaired in Alzheimer’s disease

  Tingxiang Yan, et al., bioRxiv - Neuroscience 2024

  Quote: ... or 1 µM thapsigargin (Santa Cruz Biotechnology, sc-24017).
• Localized K63 ubiquitin signaling is regulated by VCP/p97 during oxidative stress

  Austin O. Maduka, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-VCP (1:2,500, Santa Cruz Biotechnology, #sc-57492), anti-NPLOC4 (Proteintech ...
• Genetic ablation of the DNA demethylation pathway in retinal progenitor cells impairs photoreceptor development and function, leading to retinal dystrophy

  Galina Dvoriantchikova, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Opn1sw (1:200, sc-14363, Santa Cruz Biotechnology), anti-Opn1mw (1:200 ...
• The mitochondrial stress-induced protein carboxyl-terminal alanine and threonine tailing (msiCAT-tailing) promotes glioblastoma tumorigenesis by modulating mitochondrial functions

  Ting Cai, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse anti-TOMM20 (1:500, Santa Cruz, cat. 18023S), rabbit anti-MTCO2 (1:500 ...
• Mechanosensitive FHL2 tunes endothelial function

  Shailaja Seetharaman, et al., bioRxiv - Cell Biology 2024

  Quote: ... VE-Cadherin (mouse, Santa Cruz, SC-9989, 1:2000) pMLC (rabbit ...
• Amyloid-β increases MBP and MOBP translation in oligodendrocytes through dysregulation of hnRNP A2 dependent RNA dynamics

  Adhara Gaminde-Blasco, et al., bioRxiv - Molecular Biology 2024

  Quote: ... hnRNP A2/B1 (sc-374053, 1:1000, Santa Cruz), MAG (SC-166849 ...
• Telomeric lncRNA TERRA localizes to stress granules in human ALT cells

  Luca Larini, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-NXF1 (1:150, sc-136095, Santa Cruz Biotechnology) and anti-actinin (1:1000 ...
• SARS-CoV-2 Omicron Envelope T9I adaptation confers resistance to autophagy

  Susanne Klute, et al., bioRxiv - Microbiology 2024

  Quote: ... ABCG2 antibody (1:100; Santa Cruz Biotechnology, #sc-58222), rabbit anti-Strep-tag II antibody (1:450 ...
• DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects

  A Colomer-Boronat, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-OCT4 (1:300, sc-8628, Santa Cruz Biotechnology) and anti-KLF4 (1:1000 ...
• Amyloid-β increases MBP and MOBP translation in oligodendrocytes through dysregulation of hnRNP A2 dependent RNA dynamics

  Adhara Gaminde-Blasco, et al., bioRxiv - Molecular Biology 2024

  Quote: ... hnRNP A2/B1 (sc-374053, 1:500, Santa Cruz), hnRNP F (sc-32310 ...
• ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis

  Junji Zhu, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-ARIH1 (1:500, Cat# sc-390763; Santa Cruz), anti-Actin (1:2,000 ...
• Bhlhe40 limits proliferation and prevents excessive angiogenesis in mouse embryoid bodies under hypoxia

  Barbara Acosta-Iborra, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1:1000 mouse anti-CAS9 (Santa Cruz Biotechnology, SC517386), 1:5000 mouse anti-Tubulin (Sigma ...
• Molecular differences between neonatal and adult stria vascularis from organotypic explants and transcriptomics

  Matsya Ruppari Thulasiram, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti Cldn11 (1:250; Santa Cruz sc-25711), rabbit anti Kir4.1 (1:250 ...
• Differential effects of diphenyl diselenide (PhSe)₂ on mitochondria-related pathways depending on the cellular energy status in Bovine Vascular Endothelial Cells

  Letícia Selinger Galant, et al., bioRxiv - Biochemistry 2024

  Quote: ... α-GCLC (1:1000; Santa Cruz Biotechnology, CA, USA), α-GCLM (1:1000 ...
• Missense Mutant Gain-of-Function Causes Inverted Formin 2 (INF2)-Related Focal Segmental Glomerulosclerosis (FSGS)

  Balajikarthick Subramanian, et al., bioRxiv - Genetics 2024

  Quote: ... and anti-rabbit (1:4000) (Santa Cruz Biotechnology, CA). The membranes were then developed using a chemiluminescent-based substrate (Super Signal West Dura) ...
• A long-lived pool of PINK1 imparts a molecular memory of depolarisation-induced activity

  Liam Pollock, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-p53 (mouse, sc-126, 1:1000, Santa Cruz), anti-OPA1 (rabbit ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-GAPDH (1:1000, Santa Cruz SC-32233), rabbit anti-HER2/ErbB2 (1:1000 ...
• Protein CoAlation on TXNRD2 regulates mitochondrial thioredoxin system to protect against ferroptosis

  Chao-Chieh Lin, et al., bioRxiv - Cell Biology 2024

  Quote: ... Primary antibodies: COASY (1:1000, sc-393812, Santa Cruz); PRDX1 (1:1000 ...
• Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model

  Ahmed K. Elsayed, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and mouse GAPDH (1:10,000, sc-32233, Santa Cruz). After thorough TBST washing ...