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1801 - 1850 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization

  Mar Arias-Garcia, et al., bioRxiv - Cell Biology 2020

  Quote: ... YAP (G6) (Santa Cruz, 1:200), YAP/TAZ [67.3] (Santa Cruz ...
• Rapid and efficient in vivo astrocyte-to-neuron conversion with regional identity and connectivity?

  Lei-Lei Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... ALDOC (Goat; 1:100; Santa Cruz), BrdU (Rat ...
• Safb1 regulates cell fate determination in adult neural stem cells by enhancing Drosha cleavage of NFIB mRNA

  Niklas Iffländer, et al., bioRxiv - Neuroscience 2021

  Quote: ... Sox10 (Santa Cruz, goat, 1:500) and GFAP (Sigma ...
• Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation

  Tomoki Kuwahara, et al., bioRxiv - Molecular Biology 2020

  Quote: ... vacuolin-1 (500 nM, Santa Cruz), Torin 1 (1 μM ...
• Cardiac Gq receptors and calcineurin activation are not required for the hypertrophic response to mechanical left ventricular pressure overload

  Ze-Yan Yu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... CaMKIIδ (1:1000; Santa Cruz Biotechnology), p-HDAC4 (1:1500 ...
• Cardiac Gq receptors and calcineurin activation are not required for the hypertrophic response to mechanical left ventricular pressure overload

  Ze-Yan Yu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... GATA4 (1:1000; Santa Cruz Biotechnology), CaMKIIδ (1:1000 ...
• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/500 LaminB1 (Santa Cruz, 374015); 1/500 α-tubulin (BD Biosciences ...
• Mitophagy mediates beige to white transition of human primary subcutaneous adipocytes ex vivo

  Attila Vámos, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Parkin (1:750, Santa Cruz Bio-technology ...
• Prostaglandin E₁ as therapeutic molecule for Nephronophthisis and related ciliopathies

  Hugo Garcia, et al., bioRxiv - Cell Biology 2022

  Quote: ... Barttin (1/400e; Santa Cruz, sc365161), Calbindin D-28K (1/500e ...
• Hypoxia Dynamically Regulates DBC1 Ubiquitination and Stability by SIAH2 and OTUD5 in Breast Cancer Progression

  Qiangqiang Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... His (1:1000, Santa Cruz Biotech.), GST (1:1000 ...
• Hypoxia Dynamically Regulates DBC1 Ubiquitination and Stability by SIAH2 and OTUD5 in Breast Cancer Progression

  Qiangqiang Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Myc (1:1000, Santa Cruz Biotech.), HA (1:1000 ...
• Hypoxia Dynamically Regulates DBC1 Ubiquitination and Stability by SIAH2 and OTUD5 in Breast Cancer Progression

  Qiangqiang Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... HA (1:1000, Santa Cruz Biotech.), GFP (1:1000 ...
• Production and Purification of Endogenously Modified tRNA-Derived Small RNAs

  Aleksej Drino, et al., bioRxiv - Biochemistry 2020

  Quote: ... laminB (goat, Santa Cruz; 1:5.000).
• miR-1/206 down-regulates splicing factor Srsf9 to promote myogenesis

  Kristen K. Bjorkman, et al., bioRxiv - Cell Biology 2019

  Quote: ... 1:2,000 α-GFP (Santa Cruz Biotechnology ...
• An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion

  Kizhakke Mattada Sathyan, et al., bioRxiv - Molecular Biology 2019

  Quote: ... p53 (1:1000, DO1, Santa Cruz), anti-TIR1 1 ...
• OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

  Lien Verboom, et al., bioRxiv - Cancer Biology 2019

  Quote: ... IκBα (1:1000, Santa Cruz Biotechnologies), phospho-IκBα (1:1000 ...
• OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

  Lien Verboom, et al., bioRxiv - Cancer Biology 2019

  Quote: ... A20 (1:1000, Santa Cruz Biotechnologies), caspase-3 (full length and cleaved ...
• Stromal ISLR promotes intestinal regeneration and cancer by suppressing epithelial Hippo signaling

  Jiuzhi Xu, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-CD45 (1:200, Santa Cruz), anti-F4/80 (1:200 ...
• Stromal ISLR promotes intestinal regeneration and cancer by suppressing epithelial Hippo signaling

  Jiuzhi Xu, et al., bioRxiv - Cancer Biology 2019

  Quote: ... anti-Mucin2 (1:100, Santa Cruz), and anti-pSTAT3 (1:1,000 ...
• Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence

  Alberto Granzotto, et al., bioRxiv - Neuroscience 2019

  Quote: ... p-ERK1,2 1:200 (Santa Cruz); rabbit p-Akt 1:1000 (Cell Signaling) ...
• Differential effects of diet and weight on taste responses in diet-induced obese mice

  Zachary C. Ahart, et al., bioRxiv - Neuroscience 2019

  Quote: ... and PLCβ2 (1:1000, Santa Cruz). Labeling by both primary antibodies was visualized using goat-anti-rabbit CY5 secondary antibody (1:500 ...
• Rapamycin rejuvenates oral health in aging mice

  Jonathan Y. An, et al., bioRxiv - Pathology 2019

  Quote: ... RANKL (G-1, sc377079, Santa Cruz), and Mouse OPG (R&D Systems ...
• Proliferation control of kidney interstitial cells

  Sarah S. McCarthy, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-Smad4 (1:1000, Santa Cruz) and anti-β-tubulin (1:5,000 ...
• Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

  Sinae Kim, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PTGES2 (1:1000, Santa Cruz Biotechnology), anti-PTGDS (1:1000 ...
• Cyclin A2/Cdk1 is Essential for the in vivo S Phase Entry by Phosphorylating Top2a

  Miaomiao Jin, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-aPKC (1:200, Santa Cruz), anti-phos-S1213-TOP2A (1:300 ...
• Nesprin-2 accumulates at the front of the nucleus during confined cell migration

  Patricia M. Davidson, et al., bioRxiv - Cell Biology 2020

  Quote: ... and actin (Santa Cruz,1:250). For immunofluorescence experiments we used an antibody against the KASH domain of nesprin-1 (MANNES1E ...
• PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix

  Emily J Kay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GAPDH (1:1000, Santa Cruz, sc48167), β-tubulin (1:1000 ...
• Matrix Stiffness Regulates Liver Sinusoidal Endothelial Cell Function Mimicking Responses in Fatty Liver Disease

  Vaishaali Natarajan, et al., bioRxiv - Bioengineering 2020

  Quote: ... anti-ICAM-1 (Santa Cruz, CA), anti-stabilin-2 (Santa Cruz ...
• Extracellular Vesicles Analysis in the COVID-19 Era: Insights on Serum Inactivation Protocols Towards Downstream Isolation and Analysis

  Roberto Frigerio, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-Alix (1:1000, Santa Cruz), anti-TSG101 (1:1000 ...
• Defective myelination in an RNA polymerase III mutant leukodystrophic mouse

  Emilio Merheb, et al., bioRxiv - Neuroscience 2021

  Quote: ... Vinculin (Santa Cruz 73614; 1:2000), CNP (EMD MAB326R ...
• Cerebrospinal fluid formation is controlled by membrane transporters to modulate intracranial pressure

  Eva K. Oernbo, et al., bioRxiv - Neuroscience 2021

  Quote: ... sc-136239 (Santa Cruz, 1:500). Secondary antibodies ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... MyoG (1:1000, Santa Cruz Biotechnology), IGF2BP2 (1:1000 ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... MyoD (1:1000, Santa Cruz Biotechnology), MHC (0.23μg/ml ...
• Hyperglycemia enhances cancer immune evasion by inducing alternative macrophage polarization through increased O-GlcNAcylation

  Natália Rodrigues Mantuano, et al., bioRxiv - Cancer Biology 2019

  Quote: ... arginase-1 (clone H52, Santa Cruz), NOS2 (clone N20 ...
• Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing

  Fiona Jenkinson, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Clb2 1:5000 (Santa Cruz); anti-flag 1:1000 (Sigma ...
• Oxidative Modifications of Parkin Underlie its Selective Neuroprotection in Adult Human Brain

  Jacqueline M. Tokarew, et al., bioRxiv - Neuroscience 2020

  Quote: ... Lamp3 (Santa Cruz, SC5275; 1:100), LC3B (Sigma ...
• Modeling Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism–dementia Complex with Microglia Containing Cerebral Organoids Derived from Induced Pluripotent Stem Cells

  Yiling Hong, et al., bioRxiv - Neuroscience 2021

  Quote: ... Capase 1(Santa Cruz, SC-392736), Periostin/ (SC-398631 ...
• Identification of proximal SUMO-dependent interactors using SUMO-ID

  Orhi Barroso-Gomila, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-B23 (1/100) (Santa Cruz); anti-SC35 (1/100 ...
• Membrane-Tethered Mucin 1 is Stimulated by Interferon in Multiple Cell Types and Antagonizes Influenza A Virus Infection in Human Airway Epithelium

  Ethan Iverson, et al., bioRxiv - Microbiology 2021

  Quote: ... MUC4 (1G8, Santa Cruz, 1:5,000); and MX1 (N2C2 ...
• Epidermal TRPV4 ion channels regulate UVB induced sunburn by triggering inflammmasome activation and ERK signaling

  Carlene Moore, et al., bioRxiv - Physiology 2021

  Quote: ... (1:200; Santa Cruz Biotechnology Inc); rabbit anti-caspase-1(1:200 ...
• Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer

  Suzann Duan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... iNOS (1:50, Santa Cruz Biotechnology), COX-2 (1:50 ...
• THE DYNAMIC INTERPLAY BETWEEN HOMEODOMAIN TRANSCRIPTION FACTORS AND CHROMATIN ENVIRONMENT REGULATES PRONEURAL FACTOR OUTCOMES

  Cheen Euong Ang, et al., bioRxiv - Genomics 2020

  Quote: ... goat PHOX2B (1:100, Santa Cruz), rabbit-TUJI (1:1000 ...
• Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin

  Vanessa Byles, et al., bioRxiv - Cell Biology 2021

  Quote: ... SREBP-1 (Santa Cruz, sc-13551), β-actin (Sigma-Aldrich A5316) ...
• K29-Linked Ubiquitin Signaling Regulates Proteotoxic Stress Response and Cell Cycle

  Yuanyuan Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti PLK1 (Santa Cruz,1:50). Images were collected by a Leica SP5 2-photon laser scanning confocal microscope.
• K29-Linked Ubiquitin Signaling Regulates Proteotoxic Stress Response and Cell Cycle

  Yuanyuan Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti INCENP (Santa Cruz,1:100), Anti MKLP1(Santa Cruz ...
• K29-Linked Ubiquitin Signaling Regulates Proteotoxic Stress Response and Cell Cycle

  Yuanyuan Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti GAPDH (Santa Cruz, 1:2000), Anti c-Myc (Genscript ...
• Motor Protein MYO1C is Critical for Photoreceptor Opsin Trafficking and Visual Function

  Ashish K. Solanki, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rod transducin (1:250, Santa Cruz), PKCα (1:500 ...
• Motor Protein MYO1C is Critical for Photoreceptor Opsin Trafficking and Visual Function

  Ashish K. Solanki, et al., bioRxiv - Cell Biology 2021

  Quote: ... rod transducin (1:250, Santa Cruz), and 4′,6-diamidino-2-phenylendole (DAPI ...
• Akkermansia muciniphila secretome promotes α-synuclein aggregation in enteroendocrine cells

  Dionísio Pedro Amorim Neto, et al., bioRxiv - Cell Biology 2021

  Quote: ... β-actin (1:5000, Santa Cruz) or GAPDH (1:5000 ...
• Akkermansia muciniphila secretome promotes α-synuclein aggregation in enteroendocrine cells

  Dionísio Pedro Amorim Neto, et al., bioRxiv - Cell Biology 2021

  Quote: ... or GAPDH (1:5000, Santa Cruz) were used as loading controls ...