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51 - 100 of 8417 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma

  Dhana Sekhar Reddy Bandi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-beta actin (Santa Cruz #sc-47724; 1:3,000). Incubation with HRP-linked secondary antibodies (CST ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... GFP (1:1,000, Santa Cruz Biotechnology, clone B-2), Parkin (1:1,000 ...
• THE STABILIZATAION OF C-MYC BY THE NOVEL CELL CYCLE REGULATOR, SPY1, DECREASES EFFICACY OF BREAST CANCER TREATMENTS

  Rosa-Maria Ferraiuolo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and anti-ERK1/2 (Santa Cruz Biotechnology; 1:1000). Secondary antibodies were used at 1:10000 dilution in blocker for 1 hour at room temperature ...
• Sugar transporter Slc37a2 regulates bone metabolism via a dynamic tubular lysosomal network in osteoclasts

  Pei Ying Ng, et al., bioRxiv - Cell Biology 2022

  Quote: ... pERK1/2 (Santa Cruz sc-7383, 1/500 dilution), t-ERK1/2 (Promega V114A ...
• Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

  Rachel Ulferts, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-ATP6V1B1/2 (sc55544, Santa Cruz, WB 1:1000), anti-FLAG (F1804 ...
• Identification of SSX2IP/Msd1 as a Wtip-binding partner by targeted proximity biotinylation

  Bo Xiang, et al., bioRxiv - Biochemistry 2021

  Quote: ... GFP (1:1000, B-2, Santa Cruz, mouse monoclonal), Biotin (1:10000 ...
• PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 controls the transport of E-cadherin

  Giovanna Grimaldi, et al., bioRxiv - Cell Biology 2020

  Quote: ... tankyrase-1/2-rabbit polyclonal antibody (Santa Cruz Biotechnology) was used at 1:1000 for western blotting ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti Erk1/2 (1:5000; Santa Cruz Biotechnology), rabbit anti-TrkB (1:1000 ...
• Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine β-hydroxylase deficient mice

  Darshana Kapri, et al., bioRxiv - Neuroscience 2022

  Quote: ... 2) goat DCX (1:250; Santa Cruz Biotechnology, USA); 3 ...
• CDK4/6 inhibition and dsRNA sensor agonism co-operate to enhance anti-cancer effects through ER stress and immune modulation of tumour cells

  Victoria Roulstone, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PARP-1 (F-2) (sc-8007, Santa Cruz Biotechnology), anti-DNMT (ab92314 ...
• Dynamic mRNA stability changes buffer transcriptional activation during neuronal differentiation and are regulated by RNA binding proteins

  Yuan Zhou, et al., bioRxiv - Molecular Biology 2023

  Quote: ... MAP-2 (Santa Cruz, Cat# Sc-5359, 1:50), β-tubulin-III (Cell signaling ...
• Myocardin-related transcription factor drives epithelial fibrogenesis in polycystic kidney disease

  Zsuzsanna Lichner, et al., bioRxiv - Cell Biology 2024

  Quote: ... Polycystin 2 (1:500, sc-28331, Santa Cruz Biotechnology), MRTF-A (1:1000 ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... EF-2 (Santa Cruz Biotechnology, SC-166415, 1:5000) and B-TUB (Proteintech ...
• Neural mechanism of acute stress management by trace aminergic signalling in the lateral habenula

  Soo Hyun Yang, et al., bioRxiv - Neuroscience 2022

  Quote: ... Membranes were immunoblotted overnight at 4°C with anti-GFP (1:1000; B-2, Santa Cruz) as the primary antibody ...
• RCC1 depletion drives protein transport defects and rupture in micronuclei

  Molly G Zych, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-RCC1 (1:200; 2 h, refix with 4% pfa; sc-376049; Santa Cruz Biotechnology), rabbit anti-Nup133 (1:100 ...
• Parallel evolution of direct development in frogs – Skin and thyroid gland development in African Squeaker Frogs (Anura: Arthroleptidae: Arthroleptis)

  Benjamin Naumann, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Primary antibodies against proliferating cell nuclear antigen (PCNA-1, 1/200, sc-7907, Santa Cruz; PCNA-2, 1/200, M087901, Dako) were applied overnight at 4°C ...
• Characterization of basal forebrain glutamate neurons suggests a role in control of arousal and avoidance behavior

  James T. McKenna, et al., bioRxiv - Neuroscience 2020

  Quote: ... placed in a blocking solution (0.5% TX-100 in PBS + 3% NDS) and then incubated for 2 days at 4°C in goat anti-calbindin (1:200; Cat#SC7691; Santa Cruz Biotechnology, Dallas, Texas), followed by 2.5 hours incubation at RT of secondary antibody coupled to a green fluorophore (1:200 ...
• Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations

  Teresa Cunha-Oliveira, et al., bioRxiv - Cell Biology 2022

  Quote: ... with the primary antibodies against GPx-1/2 (1:1000, sc-133152, RRID: AB_2112240, Santa Cruz), catalase (1:1000 ...
• Suppressive effects of oroxylin A on intracellular proliferation of Toxoplasma gondii via host cell ERK phosphorylation inhibition

  Ziyue Z Zhang, et al., bioRxiv - Microbiology 2024

  Quote: ... mouse monoclonal antibody p-ERK 1/2 (1:1,000 dilution, sc-7383; Santa Cruz Biotechnology, Inc.), and rabbit polyclonal antibody beta-actin (1:5,000 dilution ...
• MicroRNA Profiles in Calcified and Healthy Aorta Differ: Therapeutic Impact of miR-145 and miR-378

  Ying Tang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Polyclonal total SMAD 1/5/9(8) (Santa Cruz Biotechnology ...
• Chromosome segregation fidelity is controlled by small changes in phospho-occupancy at the kinetochore-microtubule interface

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2021

  Quote: ... GAPDH (Santa Cruz G-9; IB at 1:1000), phospho-Histone H3 Ser10 (Cell Signaling Technologies #9701 ...
• A chemical biology toolbox to investigate in-cell target engagement and specificity of PRMT5-inhibitors

  Elisabeth M. Rothweiler, et al., bioRxiv - Systems Biology 2022

  Quote: ... and G-9 (s-365062, Santa Cruz, 1:200) and imaged at the Odyssey CLx (Li-cor ...
• The master energy homeostasis regulator PGC-1α couples transcriptional co-activation and mRNA nuclear export

  Simeon R. Mihaylov, et al., bioRxiv - Molecular Biology 2021

  Quote: ... TFAM (C-9) [1:1000] (Santa Cruz sc-376672), c-myc [1:1000] (Thermo Fisher MA1-980) ...
• Structural basis for BIRC6 to balance apoptosis and autophagy

  Shuo-Shuo Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Anti-procaspase-9 mouse IgG (1:100, Santa Cruz) and anti-LC3 rabbit IgG (1:100 ...
• Long-chain fatty acyl-coenzyme A activates the mitochondrial fission factors MiD49 and MiD51 by inducing their oligomerization

  Ao Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (G-9, mouse; Santa Cruz Biotechnology; 1:500), actin (mouse ...
• Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging

  María Latorre-Leal, et al., bioRxiv - Animal Behavior and Cognition 2021

  Quote: ... anti- ER-beta (Santa Cruz Biotechnology sc-53494, 1:1000), Arc (Santa Cruz Biotechnology sc-15325 ...
• GRAMD2⁺ alveolar type I cell plasticity facilitates cell state transitions in organoid culture

  Hua Shen, et al., bioRxiv - Cell Biology 2023

  Quote: ... Beta-actin (#sc-47778, 1:1000, Santa Cruz, Dallas, Texas) or GAPDH (#AM4300 ...
• Inorganic Pyrophosphate Promotes Osteoclastogenic Commitment and Survival of Bone Marrow Derived Monocytes mediated by Egr-1 up-regulation and MITF phosphorylation

  Samir M. Abdelmagid, et al., bioRxiv - Cell Biology 2020

  Quote: ... Rabbit anti-mouse phospho-ERK 1/2 (Thr202, Tyr204) (Cat# sc-136521) and ERK 1/2 (Cat# sc-292838) were purchased from Santa Cruz (Santa Cruz, CA). Anti-mouse phospho-MITF-S307 was gift from Dr Michael Ostrowski (Ohio State University ...
• DNA density is a better indicator of a nuclear bleb than lamin B loss

  Samantha Bunner, et al., bioRxiv - Cell Biology 2024

  Quote: ... Cells were incubated overnight at 4◦C or for 1 h at RT in 2%BSA PBS containing primary antibody mouse anti-lamin B1 (Santa Cruz, sc-365214, 1/500). Cells were washed using PBS and incubated for 1 h at room temperature with secondary antibody in 2% BSA PBS ...
• Ehrlichia Wnt short linear motif ligand mimetic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis

  Caitlan D. Byerly, et al., bioRxiv - Microbiology 2023

  Quote: ... α-Yap, α-TEAD(1, 3, and 4)(Santa Cruz Biotechnology, Dallas, TX), α-active β-catenin ...
• Effects of gypenosides on enteroendocrine L-cell function and GLP-1 secretion

  Chinmai Patibandla, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... cells were fixed with 4% paraformaldehyde for 10 mins at 4°C followed by 30mins blocking with 2% BSA and stained with anti-GLP-1 antibody (1:200) (Gt pAb to GLP-1, SC-26637, Santa Cruz Biotechnology) overnight in a humid chamber at 4°C ...
• Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations

  Teresa Cunha-Oliveira, et al., bioRxiv - Cell Biology 2022

  Quote: ... SOD-2 (1:1000, sc-133134, RRID: AB_2191814, Santa Cruz), SOD1 (1:2000 ...
• The “Proxitome” of Arabidopsis Processing Bodies Reveals a Condensate-Membrane Interface Instructing Actin-Driven Directional Growth

  Chen Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... rat anti-tubulin YL1/2 (1:200; Santa Cruz Biotechnology), mouse anti-DCP1 (diluted 1:100 ...
• Human-specific progenitor sub-domain contributes to extended neurogenesis and increased motor neuron production

  Sumin Jang, Elias Gunmit, Hynek Wichterle, bioRxiv - Developmental Biology 2022

  Quote: ... FOXP1 (Mouse, 1:400 Santa Cruz A-2 sc-398811), NKX2-2 (Mouse ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-TSG101 (1:200, C-2, Santa Cruz Biotechnology), mouse anti-ALIX (1:500 ...
• Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

  Christina Plattner, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-mucin 2 (Santa Cruz Biotechnology, #sc-515032, 1:500), anti-EpCAM (R&D ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... MRCKβ (A-2) (1:100; Santa Cruz Biotechnology sc-390127), Tubulin (1:200 ...
• Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors

  Sameer Farouk Sait, et al., bioRxiv - Cancer Biology 2022

  Quote: ... with ERK-2 (sc-1647; Santa Cruz Biotechnology; 1:1000) used as a loading control.
• Phase-specific signatures of wound fibroblasts and matrix patterns define cancer-associated fibroblast subtypes

  Mateusz S. Wietecha, et al., bioRxiv - Genomics 2022

  Quote: ... 2) mouse anti-periostin (1:100; Santa Cruz; #sc-398631) and rabbit anti-MFAP4 (1:100 ...
• In vitro reconstitution reveals requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

  Susanne Hellmuth, Olaf Stemmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-Rad21 (1:800; B-2, Santa Cruz Biotechnology), rabbit anti-Rad21 (1:1,000 ...
• Control of telomere length in yeast by SUMOylated PCNA and the Elg1 PCNA unloader

  Pragyan Singh, Inbal Gazy, Martin Kupiec, bioRxiv - Molecular Biology 2023

  Quote: ... 2 μl of (HA, Santa Cruz Biotechnology (sc7392; 1:1,000) or MYC ...
• Targeting the deNEDDylating enzyme NEDP1 to ameliorate ALS phenotypes through Stress Granules dissolution

  Toufic Kassouf, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-PARP-1 (F-2) (#sc-8007, Santa Cruz), mouse anti-TIA-1 (G-3 ...
• Phase transitions of a SEC14-like condensate at Arabidopsis plasma membranes regulate root growth

  Chen Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat α-tubulin YL1/2 (1:200; Santa Cruz Biotechnology), mouse α-FLAG (1:250) ...
• Thermo-optoplasmonic single-molecule sensing on optical microcavities

  Nikita A. Toropov, et al., bioRxiv - Biophysics 2023

  Quote: ... 2 µL of 1 µM tryptamine (Santa Cruz SC-206065) was added to the chamber in order to observe steps in the Δλ of the WGM.
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-TSG101 (dilution 1/200; Santa Cruz Biotechnology; C-2), anti-CD81 (dilution 1/500 ...
• Dramatic Changes in Mitochondrial Subcellular Location and Morphology Accompany Activation of the CO₂ Concentrating Mechanism

  Justin Findinier, et al., bioRxiv - Plant Biology 2024

  Quote: ... and anti-α-Tubulin (B-5-1-2, 1/500 dilution; Santa Cruz Biotechnology, Dallas, TX, USA). After a 4 h incubation with the primary antibodies at 37°C ...
• PP1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission

  Karl Foley, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PP1 (1:1,000; E-9, Santa Cruz Biotechnology, Inc.), and anti-GFP (1:1000 ...
• Multiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health

  James L. Daly, et al., bioRxiv - Neuroscience 2022

  Quote: ... ATP7A (Santa Cruz; D-9, sc-376467; 1:1000 WB), Cathepsin D (Proteintech ...
• Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development

  Cody McKee, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PP1 (1:1,000; E-9, Santa Cruz Biotechnology, Inc.), anti-pAKT (Ser473 ...
• CRISPR/Cas9-mediated knockout of the ubiquitin variant Ub^KEKS reveals a role in regulating nucleolar structures and composition

  Julie Frion, et al., bioRxiv - Cell Biology 2023

  Quote: ... UBF (F-9, sc-13125, Santa Cruz Biotechnology , 1:300) or fibrillarin (38F3 ...