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• Reversal of pulmonary veno-occlusive disease phenotypes by inhibition of the integrated stress response

  Amit Prabhakar, et al., bioRxiv - Cell Biology 2023

  Quote: ... co-stained with endothelial cell marker CD31 (sc-376764; Santa Cruz Biotechnology), and immunofluorescence signal were detected by Nikon Ts2 fluorescence microscope according to the manufacturer’s protocol.
• Specificity and promiscuity of JAK recruitment regulates pleiotropy of cytokine-receptor signaling

  Eyal Zoler, et al., bioRxiv - Biochemistry 2023

  Quote: ... mouse monoclonal anti-pSTAT6 (pY641.18) (Santa Cruz Biotechnology Inc., SC-136019), mouse monoclonal anti-α-tubulin (Sigma-Aldrich ...
• Missense mutations in CMS22 patients reveal that PREPL has both enzymatic and non-enzymatic functions

  Yenthe Monnens, et al., bioRxiv - Genetics 2023

  Quote: ... Antibodies : PREPL (Santa Cruz), FLAG M2 (Sigma Aldrich)
• The CUL4-DDB1-DCAF1 E3 ubiquitin ligase complex regulates PLK4 protein levels to prevent premature centriole duplication

  Josina Grossmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... α-CUL4 (H-11, catalog no.: sc-377188) and α-cyclin E1 (HE12, catalog no.: sc-247) antibodies were purchased from Santa Cruz Biotechnology ...
• The CUL4-DDB1-DCAF1 E3 ubiquitin ligase complex regulates PLK4 protein levels to prevent premature centriole duplication

  Josina Grossmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... cells were treated with 2 mM thymidine (Santa Cruz Biotechnology, catalog no.: sc-296542A) for 18 h ...
• The CUL4-DDB1-DCAF1 E3 ubiquitin ligase complex regulates PLK4 protein levels to prevent premature centriole duplication

  Josina Grossmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... 100 μg/ml cycloheximide (ChemCruz, Santa Cruz Biotechnology, catalog no.: sc-3508) was added to block protein synthesis ...
• FOXA2 is essential for maintaining the urea cycle in acute liver failure

  Rilu Feng, et al., bioRxiv - Molecular Biology 2023

  Quote: ... A non-targeting negative stealth siRNA (scrambled, sc-37007, Santa Cruz) was used as a negative control ...
• Rapid dexamethasone treatment inhibits LPS-induced cytokine storm in mice

  Fen Zhang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 60µL of Protein A/G PLUS-agarose beads (Santa Cruz Biotechnology, Texas, USA) and 4µg of single-stranded herring sperm DNA were added to each sample ...
• The Wolfram-like variant WFS1^E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice

  Simone Patergnani, et al., bioRxiv - Neuroscience 2023

  Quote: ... cells were reconstituted for 2 hours with 5 µM coelenterazine wt (Santa Cruz Biotechnology) in DMEM high glucose supplemented of 0.1% FBS and transferred to the perfusion chamber ...
• KSR1 knockout mouse model demonstrates MAPK pathway’s key role in cisplatin- and noise-induced hearing loss

  Matthew A. Ingersoll, et al., bioRxiv - Neuroscience 2023

  Quote: ... from BD Transduction Laboratories and anti–β-actin (C4; SC- 47778) from Santa Cruz. The antibodies were used at dilutions ranging from 1:250 to 1:1,000.
• Galectin-3 depletion tames pro-tumoural microglia and restrains cancer cells growth

  Luis Cruz Hernández, et al., bioRxiv - Neuroscience 2023

  Quote: ... Cells were knocked down by small interfering RNA (siRNA) targeting galectin-3 (Santa Cruz Biotechnology, USA ref: sc-155994-SH) according to the manufacturer’s siRNA transfection protocol.
• The E3 ubiquitin ligase RNF216 contains a linear ubiquitin chain-determining-like domain that functions to regulate dendritic arborization and dendritic spine type in hippocampal neurons

  Jayashree Kadirvelu, et al., bioRxiv - Neuroscience 2023

  Quote: ... Anti-ubiquitin (P4D1) (Santa Cruz Biotechnology, sc-8017), anti-Flag (Sigma-Aldrich ...
• Tau alters global gene expression affecting chromatin in the early stages of Alzheimer’s disease

  G. Siano, et al., bioRxiv - Neuroscience 2023

  Quote: ... The antibodies for IF were as follows: mouse anti-Tau (Tau13) 1:500 (Santa Cruz Biotechnology), rabbit anti-HP1a 1:250 (Abcam) ...
• The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function – insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation

  Daniel Bull, et al., bioRxiv - Neuroscience 2023

  Quote: ... The primary antibodies: anti-PLCγ2 mouse antibody (sc-5283, 1:50, Santa Cruz) and anti-GAPDH mouse antibody (ab8245 ...
• Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome

  Kritika Bhalla, et al., bioRxiv - Neuroscience 2023

  Quote: ... PREPL deficiency in all the clones was verified by Western blot using anti-PREPL antibody (Santa Cruz). Primers for cloning of the guide sequence and Sanger sequencing for HEK293T and βTC3 cells are listed in Supplementary table 2 and 3 respectively.
• Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo

  Mohamed R. Ahmed, et al., bioRxiv - Neuroscience 2023

  Quote: ... and the supernatants were incubated overnight at 4°C with mouse anti-JNK3 antibody (Santa Cruz Biotechnology). Protein G slurry (20 μl ...
• Hyperactive PI3Kinase delta enables long distance regeneration of the rat corticospinal tract

  Kristyna Karova, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-PKCγ (1:1000, Santa Cruz, Dallas, TX, USA, sc166451 A-7 clone), mouse anti-cFOS (1:500 ...
• Tau alters global gene expression affecting chromatin in the early stages of Alzheimer’s disease

  G. Siano, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-GAPDH 1:10000 (Santa Cruz Biotechnology), HRP-conjugated anti-mouse 1:1000 (Santa Cruz Biotechnology) ...
• Reprogramming early cortical astroglia into neurons with hallmarks of fast-spiking parvalbumin-positive interneurons by phospho-site deficient Ascl1

  Nicolás Marichal, et al., bioRxiv - Neuroscience 2023

  Quote: ... The following primary antibodies were used: anti-Doublecortin (Dcx, goat, 1:250, Santa Cruz Biotechnology ...
• Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and aging

  Bidur Paudel, et al., bioRxiv - Neuroscience 2023

  Quote: ... HNF-3β RY7 (FOXA2) (mouse mAb, Santa Cruz # sc-101060, 1:100 IF), TUJ1 (mouse mAb ...
• A spatially resolved EGFR signaling model predicts the length scale of GAB1-SHP2 complex persistence

  Paul J. Myers, et al., bioRxiv - Systems Biology 2023

  Quote: ... mouse SHP2 antibody (sc-7384, 1:50; Santa Cruz Biotechnology, Santa Cruz, CA) and rabbit GAB1 antibody (HPA049599 ...
• Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model

  Ming-Song Lee, et al., bioRxiv - Bioengineering 2023

  Quote: ... and COL10A1 (Santa Cruz Biotechnology) at a 1:200 ratio for 1 hour at 4°C ...
• Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model

  Ming-Song Lee, et al., bioRxiv - Bioengineering 2023

  Quote: ... COL2A1 (Santa Cruz Biotechnology), and COL10A1 (Santa Cruz Biotechnology ...
• A developmentally-inspired hypoxia condition promotes kidney organoid differentiation from human pluripotent stem cells

  Hyeonji Lim, et al., bioRxiv - Bioengineering 2023

  Quote: ... and anti-goat (1:5000) (sc-2020, Santa Cruz Biotechnology) antibodies ...
• CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair

  Dalia Hassan, Jichao Chen, bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-homeodomain only protein (HOPX, 1:250, sc-398703 AF647, Santa Cruz). rat anti-KI67 (KI67 ...
• Left-right asymmetry is formed in the basal bodies of the mouse node cilia in a cilia motility-dependent manner

  Hiroshi Yoke, Atsushi Taniguchi, Shigenori Nonaka, bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-centriolin monoclonal antibody (sc-365521, Santa Cruz), rabbit anti-ninein polyclonal antibody (PA5-96974 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CHMP7 (sc-271805, 1:1000, Santa Cruz Biotechnology) and anti-TSG101 antibody (ab133586 ...
• APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

  Brandon L Mouery, et al., bioRxiv - Cell Biology 2023

  Quote: ... Geminin (1:3000; rabbit; sc-13015; Santa Cruz Biotechnology; milk), Cdt1 (1:1000 ...
• Elucidating the Synergistic Role of Elm1 and Gin4 Kinases in Regulating Septin Hourglass Assembly

  Joseph Marquardt, Xi Chen, Erfei Bi, bioRxiv - Cell Biology 2023

  Quote: ... and mouse anti-Cdc28 (1:3000 dilution, sc-515762, Santa Cruz, Dallas, TX, USA) primary antibodies ...
• Liver regeneration by a population of midzone-located mesenchymal-hepatocyte hybrid cells

  Guo Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Actin (1:5000, Santa Cruz Biotechnology, 81178).
• GRAMD2⁺ alveolar type I cell plasticity facilitates cell state transitions in organoid culture

  Hua Shen, et al., bioRxiv - Cell Biology 2023

  Quote: ... HOPX (1:50, #SC398703, Santa Cruz), acetylated anti-tubulin (Ac-TUB ...
• The 21-base pair deletion mutant Calpain 3 does not inhibit wild-type Calpain 3 activity

  Swati Maitra, et al., bioRxiv - Cell Biology 2023

  Quote: ... Calpastatin (Proteintech and Santa Cruz Biotechnology, 1:1000), Actin (Proteintech and Santa Cruz Biotechnology ...
• Prolonged over-expression of PLK4 amplifies centrosomes through formation of inter-connected centrosome rosette clusters

  Selahattin Can Özcan, et al., bioRxiv - Cell Biology 2023

  Quote: ... Rootletin (Santa Cruz Biotechnology; sc-374056) at 1/500 dilution ...
• Prolonged over-expression of PLK4 amplifies centrosomes through formation of inter-connected centrosome rosette clusters

  Selahattin Can Özcan, et al., bioRxiv - Cell Biology 2023

  Quote: ... Anti-C-Nap1 (Santa Cruz Biotechnology; 390540), Anti-Rootletin (Santa Cruz Biotechnology ...
• Prolonged over-expression of PLK4 amplifies centrosomes through formation of inter-connected centrosome rosette clusters

  Selahattin Can Özcan, et al., bioRxiv - Cell Biology 2023

  Quote: ... Anti-Rootletin (Santa Cruz Biotechnology; sc-374056), Anti-Nek2 (BD ...
• Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD

  Elias Adriaenssens, et al., bioRxiv - Cell Biology 2023

  Quote: ... Bafilomycin A1 (sc-201550, Santa Cruz Biotech), TBK1 inhibitor GSK8612 (S8872 ...
• Genetic Discovery Enabled by A Large Language Model

  Tao Tu, et al., bioRxiv - Genetics 2023

  Quote: ... The membranes were incubated with a 1:1000 dilution of mouse monoclonal anti-µ-crystallin antibody (F-11) (Santa Cruz Biotechnology) or with a 1:4000 dilution of a mouse monoclonal anti-α-tubulin antibody (clone B 5-1-2 ...
• The balance between ATR and DDK activities controls TopBP1-mediated locking of dormant origins at the pre-IC stage

  Stéphane Koundrioukoff, et al., bioRxiv - Genetics 2023

  Quote: Mouse anti-TFIIIB90C (sc-1887, Santa Cruz Biotechnology)
• The balance between ATR and DDK activities controls TopBP1-mediated locking of dormant origins at the pre-IC stage

  Stéphane Koundrioukoff, et al., bioRxiv - Genetics 2023

  Quote: Mouse anti-TopBP1 (sc-271043, Santa Cruz Biotechnology)
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... or mouse IgG isotype antibody (2μg, Santa Cruz Biotechnology, Cat# sc-2025) for 1h at 4°C and antibody-chromatin complexes were selectively collected by protein A spin columns ...
• NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation

  Tao Yu, et al., bioRxiv - Immunology 2023

  Quote: ... supernatant was incubated with anti-NLRP3 or anti-ZDHHC7 antibody as indicated and Protein A/G conjugated agarose beads (Santa Cruz) to immunoprecipitate endogenous NLRP3 or ZDHHC7 proteins ...
• CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy

  Marta Zaninello, et al., bioRxiv - Cell Biology 2023

  Quote: ... polyclonal rabbit anti-TOM20 (sc-114115, Santa Cruz Biotechnology), monoclonal mouse anti-β- TubulinIII (T8660 ...
• NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation

  Tao Yu, et al., bioRxiv - Immunology 2023

  Quote: ... siRNA targeting human ZDHHC7 gene (sc-93249) and mouse Zdhhc7 gene (sc-155507) were purchased from Santa Cruz Biotechnology.
• The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

  Mays Mohammed Salih, et al., bioRxiv - Immunology 2023

  Quote: ... and probed with primary antibodies overnight with either HNRNPA2B1 (1:1000, Santa Cruz Biotech, Sc-374053), pSTAT3 (1:500 ...
• Initiation of a ZAKα-dependent Ribotoxic Stress Response by the Innate Immunity Endoribonuclease RNase L

  Jiajia Xi, et al., bioRxiv - Immunology 2023

  Quote: ... IKKý inhibitor (BAY11-7082, Santa Cruz, sc-200615B); and ZAK inhibitors (3h and 6p ...
• The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization

  Devanarayanan Siva Sankar, et al., bioRxiv - Cell Biology 2023

  Quote: ... AMBRA1 (Santa Cruz Biotechnologies, sc-398204, mouse), RAB7 (ABcam ...
• Helicobacter pylori cancer associated CagA protein drives intestinal metaplastic transition in human gastric organoids

  Mar Reines, et al., bioRxiv - Cell Biology 2023

  Quote: ... We used antibodies against N-terminal CagA b-300 (Santa Cruz Cat. No. sc-25766), C-terminal CagA bk-20 (Santa Cruz Cat ...
• PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function

  Hua He, et al., bioRxiv - Developmental Biology 2023

  Quote: Primary antibodies used include: Mouse anti-HOP (Santa Cruz Biotechnology sc-398703; 1:100), Guinea Pig anti-pro-SFTPC (In house ...
• A root-specific NLR network confers resistance to plant parasitic nematodes

  Daniel Lüdke, et al., bioRxiv - Plant Biology 2023

  Quote: ... Mouse monoclonal anti-GFP antibody conjugated to HRP (B-2, Santa Cruz Biotech; 1:5000 dilution) or mouse monoclonal anti-mCherry TrueMAB antibody conjugated to HRP (OTI10G6 ...
• Glucocorticoid intermittence coordinates rescue of energy and mass in aging-related sarcopenia through the myocyte-autonomous PGC1alpha-Lipin1 transactivation

  Ashok Daniel Prabakaran, et al., bioRxiv - Physiology 2023

  Quote: ... Secondary antibodies (diluted 1:5000 for 1-hour incubation at room temperature): HRP-conjugated donkey anti-rabbit or anti-mouse (#sc-2313 and #sc-2314, Santa Cruz Biotech, Dallas, TX). Counterstain for loading control was performed with ponceau (#P7170 ...