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5701 - 5750 of 10000+ citations since 2019

• MITF regulates IDH1 and NNT and drives a transcriptional program protecting cutaneous melanoma from reactive oxygen species

  Elisabeth Roider, et al., bioRxiv - Cancer Biology 2023

  Quote: ... samples were pre-cleared with 5 μg of normal rabbit IgG (Santa Cruz Biotechnology) and 80 μl of 50% protein A/G slurry containing 0.25 mg/mL sonicated salmon sperm DNA and 1 mg/mL BSA for 2 hours at 4°C ...
• Reprogramming of 3D chromatin domains by antagonizing the β-catenin/CBP interaction attenuates insulin signaling in pancreatic cancer

  Yufan Zhou, et al., bioRxiv - Cancer Biology 2023

  Quote: RHBDD1 and control shRNA plasmids were purchased from Santa Cruz Biotechnology (sc-94654-SH ...
• The DNA Damage Response (DDR) landscape of endometrial cancer defines discrete disease subtypes and reveals therapeutic opportunities

  Xingyuan Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PCNA (Santa Cruz, #sc-56).
• Pharmacological modulation of the cytosolic oscillator affects glioblastoma cell biology

  Paula M Wagner, Mario E Guido, bioRxiv - Cancer Biology 2023

  Quote: ... CHIR99021 (GSK-3 Inhibitor XVI, Santa Cruz), or KL001 (Cryptochrome protein stabilizer ...
• An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat

  Mikaela Behm, et al., bioRxiv - Cancer Biology 2023

  Quote: Tissues or tumours were fixed overnight with 4% paraformaldehyde (PFA) (Santa Cruz Biotechnology), transferred to 70% ethanol and then embedded into paraffin ...
• An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat

  Mikaela Behm, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or II) 0.25% trypsin (Santa Cruz Biotechnology) for 2 hours followed by incubation with dissociation buffer for 1 hour ...
• Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis

  Sahar F. Bannoura, et al., bioRxiv - Cancer Biology 2023

  Quote: ... cultured cells were lysed in RIPA buffer (Santa Cruz Biotechnology) with protease and phosphatase inhibitors ...
• CtBP2 triggers CCN1-induced metastatic dissemination of osteosarcoma cells in a non-hypoxic microenvironment

  Laura Di Patria, et al., bioRxiv - Cancer Biology 2023

  Quote: ... shRNA sequences were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Briefly ...
• Selective Impact of ALK and MELK Inhibition on ERα Stability and Cell Proliferation in Cell Lines Representing Distinct Molecular Phenotypes of Breast Cancer

  Stefania Bartoloni, et al., bioRxiv - Cancer Biology 2023

  Quote: ... were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Additionally ...
• SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma

  Brianna R Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-β-actin (Sigma AC-15; 1:5,000 or Santa Cruz Biotechnology sc-47778 ...
• Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

  Yi Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Twist1 (RRID:AB_1130910; 1:500, Cat. No. CS-81417, Santa Cruz Biotechnology), anti-Vimentin (RRID:AB_10695459 ...
• Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

  Cheng Lian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-PRMT5 monoclonal antibody (Santa cruz, sc-376937); Anti-PRMT7 rabbit polyclonal antibody (Abclonal ...
• Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

  Cheng Lian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-PRMT1 monoclonal antibody (Santa cruz, sc-166963); Anti-PRMT5 monoclonal antibody (Santa cruz ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Samples were incubated with preblocked protein A/G Plus beads (Santa Cruz Biotechnology, #2003, RRID:AB_10201400) for 2 h at 4°C ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... RRID:AB_631346),anti-cyclin A (Santa Cruz Biotechnology, #sc-751, RRID:AB_631329), anti-cyclin B1 (Santa Cruz Biotechnology ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-cyclin B1 (Santa Cruz Biotechnology ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-p300 (Santa Cruz Biotechnology ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-p27 (Santa Cruz Biotechnology, #sc-527, RRID:AB_632131), anti-p300 (Santa Cruz Biotechnology ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-vinculin (Santa Cruz Biotechnology ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-cyclin E (Santa Cruz Biotechnology, #sc-198, RRID:AB_631346),anti-cyclin A (Santa Cruz Biotechnology ...
• SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma

  Brianna R Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Western blots were developed by multiplex Western blotting using anti-SOS1 (Santa Cruz sc-256; 1:500), anti-SOS2 (Santa Cruz sc-258 ...
• Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells

  Sefora Conti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:200 (Santa Cruz, cat. no. sc-271134); mouse anti-CK20 ...
• A Novel Imaging Method (FIM-ID) Reveals that Myofibrillogenesis Plays a Major Role in the Mechanically Induced Growth of Skeletal Muscle

  Kent W. Jorgenson, et al., bioRxiv - Cell Biology 2023

  Quote: ... sections were incubated overnight in blocking solution containing mouse IgG1 anti-SERCA1 (1:100, VE121G9, Santa Cruz #SC-58287) and rabbit anti-dystrophin (1:100 ...
• A Novel Imaging Method (FIM-ID) Reveals that Myofibrillogenesis Plays a Major Role in the Mechanically Induced Growth of Skeletal Muscle

  Kent W. Jorgenson, et al., bioRxiv - Cell Biology 2023

  Quote: ... sections were incubated overnight in blocking solution containing mouse IgG1 anti-SERCA1 or mouse IgG1 anti-SERCA2 (1:200, Santa Cruz #SC-53010) and rabbit anti-dystrophin ...
• Phosphorylation of MYCN and MAX by PAK family kinases is a novel tumor-suppressor mechanism in neuroblastoma with potential therapeutic implications

  Esteban J Rozen, Kim Wigglesworth, Jason Shohet, bioRxiv - Cancer Biology 2023

  Quote: ... c-MYC (sc-40) and MAX (sc-8011) from Santa Cruz Biotechnology ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-p21 (Santa Cruz Biotechnology, #sc-397, RRID:AB_632126), anti-p27 (Santa Cruz Biotechnology ...
• The anti-B7-H3 blocking antibody MJ18 does not recognize B7-H3 in murine tumor models

  Talah Nammor, et al., bioRxiv - Cancer Biology 2023

  Quote: B7-H3 (cd276) was knocked-out in tumor cell lines using CRISPR/Cas9 KO plasmids from Santa Cruz Biotechnology (human ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GAPDH 1/10,000 (Santa Cruz, sc-47724), HA-Tag (Abcam ...
• Biochemically-functionalized probes for cell type-specific targeting and recording in the brain

  Anqi Zhang, Theodore J. Zwang, Charles M. Lieber, bioRxiv - Bioengineering 2023

  Quote: ... Alomone Labs) or 5 µM of antibodies for targeting neurons with dopamine receptor 2 (D2R) (anti-D2DR, sc-5303, Santa Cruz Biotechnology) or without cell type specificity (rabbit anti-human IgG ...
• A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

  Samuel Abassah-Oppong, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Selected cryo-sections were then incubated overnight with the following primary antibodies: anti-Shox2 (1:300, Santa Cruz JK-6E, sc-81955), anti-SMA-Cy3 (1:250 ...
• A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis

  George Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and GAPDH (sc-32233, Santa Cruz Biotechnology, RRID:AB_627679) were used.
• Integrative Modelling of Signalling Network Dynamics Identifies Cell Type-selective Therapeutic Strategies for FGFR4-driven Cancers

  Sung-Young Shin, et al., bioRxiv - Systems Biology 2023

  Quote: ... The following antibodies were purchased from Santa Cruz Biotechnology ...
• The ASC inflammasome adapter controls the extent of peripheral protein aggregate deposition in inflammation-associated amyloidosis

  Marco Losa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The following assay positive controls were used at a starting concentration of 1 µg/ml: (1) Anti-ASC/TMS1/PYCARD Antibody (B-3) mouse monoclonal IgG1 (sc-514414, Santa Cruz); (2 ...
• The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions

  Mark S. Lee, et al., bioRxiv - Immunology 2023

  Quote: ... 1.5μL anti-LCK (PE conjugate, clone 3A5, Santa Cruz Biotechnology), and 1μL CTxB (AF 488 conjugate ...
• Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells

  Kyle A. Cottrell, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Fibrillarin (Santa Cruz, sc-25397), beta-tubulin (Abcam ...
• Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells

  Kyle A. Cottrell, et al., bioRxiv - Molecular Biology 2023

  Quote: ... ISG15 (Santa Cruz, sc-166755), cleaved PARP (Cell Signaling ...
• SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns

  Kazuhiro Fukumura, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The lysate was centrifuged to remove debris and the supernatant was rocked at 4°C for 2 h with an anti-Flag antibody (anti-DDDDK tag, MBL Life Science) or mouse anti-IgG antibody (Santa Cruz Biotechnology) that was conjugated with ‘Dynabeads Protein A’ (Veritas ...
• Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells

  Kyle A. Cottrell, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Fibrillarin (Santa Cruz, sc-25397), DDX54 (Novus Biologicals ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GFP (Santa Cruz Bio cat.no. sc-9996, 1:1,000). The following secondary antibodies were used ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Rad51 (Santa Cruz Bio cat.no. sc-8349, 1:1,000), PARP1 (Enzo Life Sciences cat ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... PCNA (Santa Cruz Bio cat. no. sc-56, 1:1,000), GAPDH (Abcam cat.no ...
• Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

  Hélène Lasolle, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (1:400; Santa Cruz Biotechnology), and β-Actin (1:1,1000 ...
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HOPX (#sc-398703, Santa Cruz Biotechnology, 1:50), RAGE (#sc-365154 ...
• Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors

  Anderson R Frank, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:5,000 (Santa Cruz sc-137243); anti-LDHB ...
• Lysosomal acid lipase-activity as a novel target to efficiently address triple-negative breast cancer high malignancy

  H. Steigerwald, et al., bioRxiv - Cancer Biology 2023

  Quote: ... β-actin and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) expression were determined using mouse antibodies sc-47724 and sc-47778 (Santa Cruz) (1:2500 ...
• Unlocking DNA Damage Sensitivity of Cancer Cells: The Potential of Splicing Inhibitors

  Ksenia S. Anufrieva, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and subsequently treated with pladienolide B (Santa Cruz Biotechnology ...
• Differential Activity of MAPK signalling Defines Fibroblast Subtypes in Pancreatic Cancer

  Lisa Veghini, et al., bioRxiv - Cancer Biology 2023

  Quote: ... KRT81 (sc-100929, Santa Cruz Biotechnology Inc.), and FAP (#ab53066 ...
• ASCT2 is the primary serine transporter in cancer cells

  Kelly O. Conger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PSPH (Santa Cruz, sc-365183), ERα (Cell Signaling ...
• ASCT2 is the primary serine transporter in cancer cells

  Kelly O. Conger, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ASCT1 (Santa Cruz, sc-393157), SNAT1 (Cell Signaling ...
• Small molecule STAT3/5 inhibitors exhibit therapeutic potential in acute myeloid leukemia and extra-nodal natural killer/T cell lymphoma

  Daniel Pölöske, et al., bioRxiv - Cancer Biology 2023

  Quote: ... the G-2 antibody (sc-1656, Santa Cruz Biotechnology) was used ...