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5101 - 5150 of 8287 citations for 6 Phenyl 1H imidazo 1 2 b pyrazole since 2019

• Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD-LID interaction

  Qiong Fan, et al., bioRxiv - Molecular Biology 2019

  Quote: ... RXRα (sc-553, Santa Cruz Biotechnology, Dallas, TX, USA; 1:1000), ChREBP (NB400-135 ...
• Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

  Hebah Sindi, et al., bioRxiv - Cell Biology 2019

  Quote: ... human/mouse p65 (1:1000, Santa Cruz Biotechnology, SC-372-G) and human/mouse pSer536-p65 (1:1000 ...
• Positive allosteric modulation of metabotropic glutamate receptor 5 modulates Akt and GSK3β signaling in vivo

  Kari A Johnson, P. Jeffrey Conn, bioRxiv - Neuroscience 2019

  Quote: ... and total GSK3α/β (Santa Cruz Biotechnology #sc-7291, 1:250). Membranes were then incubated with IRDye-conjugated secondary antibodies (IRDye 680 for phosphoproteins ...
• Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

  Yuta Higashikuse, et al., bioRxiv - Developmental Biology 2019

  Quote: ... myc (1:400 in 5% BSA/TBST, clone 9E10, Santa Cruz), GAPDH (1:1000 in 5% BSA/TBST ...
• In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of cardiomyocyte proliferative potential

  Stephen Cutie, Dominic Lunn, Guo N. Huang, bioRxiv - Developmental Biology 2019

  Quote: ... rabbit anti-PCM1 (H262) (1:200) (Santa Cruz Biotechnology SC-67204), Alexa Fluor 488 donkey anti-rabbit IgG (Molecular Probes 1874771 ...
• Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes

  Laura N. Zamproni, et al., bioRxiv - Neuroscience 2019

  Quote: ... and HRP-conjugated secondary antibodies (1:5000, Santa Cruz, Dallas, USA.). The blots were then visualized using the SuperSignal™ West Pico (Thermo Fischer ...
• Knocking out non-muscle myosin II in retinal ganglion cells promotes long-distance optic nerve regeneration

  Xue-Wei Wang, et al., bioRxiv - Neuroscience 2019

  Quote: ... Mouse anti-Atf3 primary antibody (1:100) was from Santa Cruz Biotechnology ...
• The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGF-beta; signaling in triple-negative breast cancer

  Zane A Gibbs, et al., bioRxiv - Cancer Biology 2020

  Quote: ... c-Myc (sc-789; 1:1000; Santa Cruz Biotechnology; Dallas, TX), V5 (13202 ...
• Synergic action of Vitamin D₃ and 17β-estradiol on behavioral impairments induced by unpredictable mild stress in the adult ovariectomized female rats

  Denis Baranenko, et al., bioRxiv - Animal Behavior and Cognition 2019

  Quote: ... the membranes were probed with anti-BDNF (1:1000, Santa Cruz) and β-actin (1:1000 ...
• Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

  Sinae Kim, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-PTGES1 (1:500; Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-PTGES2 (1:1000 ...
• Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

  Sinae Kim, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-PTGES1 (1:500; Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-PTGES2 (1:1000 ...
• Colocalization of IQGAP1 with DLC-1 and PLC-δ1; Its potential role in coronary spasm

  Makoto Tanaka, et al., bioRxiv - Molecular Biology 2019

  Quote: ... rabbit polyclonal anti-p122RhoGAP/DLC-1 (sc-32931; Santa Cruz Biotechnology), mouse monoclonal ant-PLC-δ1 (sc-374329 ...
• Cortical Foxp2 supports behavioral flexibility and developmental dopamine D1 receptor expression

  Marissa Co, et al., bioRxiv - Neuroscience 2019

  Quote: ... mouse a-DARPP-32 (#sc-271111, Santa Cruz Biotechnology, 1:250), rabbit a-FOXP2 (#5337S ...
• Low oxygen enhances trophoblast column growth by potentiating the extravillous lineage and promoting LOX activity

  Jenna Treissman, et al., bioRxiv - Developmental Biology 2019

  Quote: ... mouse monoclonal IgG (1:50, RCK105, Santa Cruz Biotechnology, Dallas, TX); anti-cytokeratin 7 ...
• NMD is required for timely cell fate transitions by fine-tuning gene expression and controlling translation

  Elena Galimberti, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:15000 for goat anti-mouse IgG (Santa Cruz, sc-2064). Chemiluminescence signal from antibody binding was detected using ECL Select detection kit (GE healthcare ...
• TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy

  Xi Yang, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse anti-GFP (1:500; sc-9996, Santa Cruz Biotechnology, Inc.), rabbit anti-GFP (1:3000 ...
• Measuring mRNA translation in neuronal processes and somata by tRNA-FRET

  Bella Koltun, et al., bioRxiv - Neuroscience 2019

  Quote: ... and ß-actin (1:12,000; #sc1616, Santa Cruz Biotechnology, Dallas, TX) in 5% BSA in TBST at 4°C and subsequently washed thrice for 5 minutes with TBST ...
• Pkd1 mutation has no apparent effects on peroxisome structure or lipid metabolism

  Takeshi Terabayashi, et al., bioRxiv - Genetics 2021

  Quote: ... a rabbit anti-Tom20 (Santa Cruz Biotechnology, FL-145, 1: 100), or a mouse anti-HA (MBL ...
• The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis

  Samuel Rivero-Hinojosa, et al., bioRxiv - Genomics 2021

  Quote: ... and 1:2000 of anti-goat secondary antibody (sc2020, Santa Cruz). CTCF protein was detected with anti-CTCF B-5 (sc-271514 ...
• LIN28B controls the regenerative capacity of neonatal murine auditory supporting cells through activation of mTOR signaling

  Xiaojun Li, Angelika Doetzlhofer, bioRxiv - Developmental Biology 2020

  Quote: ... goat anti-SOX2 (Santa Cruz Biotechnology, no. sc-17320, 1:500) and rabbit anti-p-S6 (Ser240/244 ...
• Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

  Karine Pozo, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and rabbit anti-β-tubulin (1:2000, Santa Cruz sc-5274). Secondary antibodies were HRP-conjugated goat anti-Rabbit IgG (H+L ...
• The dynamic equilibrium of nascent and parental MCMs safeguards replicating genomes

  Hana Sedlackova, et al., bioRxiv - Cell Biology 2019

  Quote: ... cyclin A (rabbit, Santa Cruz, sc-751, 1:500 for IF), FLAG M2 (mouse ...
• Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia

  Derek H. Janssens, et al., bioRxiv - Genomics 2021

  Quote: ... and Mouse anti-KMT2A (1:100, Santa Cruz Cat #sc-374392) refered to as KMT2A-C2 ...
• Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories

  Sophie G Kellaway, et al., bioRxiv - Genomics 2020

  Quote: ... at 1:200 or anti-CBFβ (sc-56751, Santa Cruz Biotechnology) and secondary Alexa Fluor 488-conjugated anti-rabbit (Jackson ImmunoResearch ...
• Subcellular dynamics and functional activity of the cleaved Na⁺ channel β1 subunit intracellular domain

  Alexander S. Haworth, et al., bioRxiv - Cell Biology 2021

  Quote: ... and L-685,458 (1 - 10 μM, 24 h, Santa Cruz Biotech). DMSO was the vehicle for all drugs and DMSO concentration did not exceed 1:1000 at working concentration ...
• Chronic Exposure to Glucocorticoids Induces Suboptimal Decision-Making in Mice

  Lidia Cabeza, et al., bioRxiv - Neuroscience 2020

  Quote: ... or anti-CRF (mouse; 1:250; sc-293187, Santa Cruz Biotechnology) primary antibodies and HRP anti-Mouse Ig (goat ...
• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... Synaptophysin (1:200, Santa Cruz Biotechnology, Santa Cruz, CA, cat. # 17750), BDNF (1:200 ...
• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... BDNF (1:200, Santa Cruz Biotechnology, Santa Cruz, CA, cat. # 546), PSD95 (1:1000 ...
• The role of sigma-1 receptor in organization of endoplasmic reticulum signaling microdomains

  Vladimir Zhemkov, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-TOM20 antibodies (FL-145, 1:500, Santa Cruz Biotechnology) overnight at 4°C ...
• p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis

  André-Claude Mbouombouo Mfossa, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-γ-tubulin (goat, 1:100, Santa Cruz Biotechnology (sc-7396)) ...
• p53 drives premature neuronal differentiation in response to radiation-induced DNA damage during early neurogenesis

  André-Claude Mbouombouo Mfossa, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-β-catenin (mouse, 1:100, Santa Cruz Biotechnology (sc-7963)) ...
• Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain

  Johannes Knabbe, et al., bioRxiv - Neuroscience 2020

  Quote: ... and Ankyrin G (1:200, Santa Cruz, Company ID: sc-28561)
• Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

  Julia E. Gerson, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-A1UP for UBQLN4 (Santa Cruz, cat. #sc-136145; 1:2000), anti-Histone H3 (Cell Signaling ...
• Structural and functional elucidation of NF-κB signaling by the p75 neurotrophin receptor through recruitment of TRADD

  Ning Zhang, et al., bioRxiv - Biophysics 2021

  Quote: ... polyclonal anti-P65 NF-κB (Santa cruz, sc-372, 1:500) and polyclonal anti-cleaved caspase 3 (Cell signal ...
• DYT-TOR1A Subcellular Proteomics Reveals Selective Vulnerability of the Nuclear Proteome to Cell Stress

  Kunal Shroff, Zachary F. Caffall, Nicole Calakos, bioRxiv - Neuroscience 2021

  Quote: ... anti-Na+/K+ - ATPase (Santa Cruz Biotechnology; sc-21712; 1:500), anti-BiP (Santa Cruz Biotechnology ...
• RAD51AP1 mediates RAD51 activity through nucleosome interaction

  Elena Pires, et al., bioRxiv - Biochemistry 2021

  Quote: ... α-RAD54 (F-11; sc-374598; Santa Cruz Biotechnology; 1:500); α-RAD51 (Ab-1 ...
• Cell Surface Glycan Engineering Reveals that Matriglycan Alone can Recapitulate Dystroglycan Binding and Function

  M. Osman Sheikh, et al., bioRxiv - Biochemistry 2021

  Quote: ... The anti-core β-DG mAb 7D11 (1:1000, Santa Cruz) was detected by secondary antibody donkey anti-mouse IgG IR680RD (1:10,000 ...
• Modeling airway dysfunction in asthma using synthetic mucus biomaterials

  Daniel Song, et al., bioRxiv - Bioengineering 2020

  Quote: ... and mouse monoclonal anti-MUC5B (Santa Cruz, sc-21768, 1:100). Primary antibody incubation was over night at 4°C in 1% BSA in PBS ...
• Convergent evolution between PALI1 and JARID2 for the allosteric activation of PRC2

  Qi Zhang, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-rabbit HRP-conjugated (Santa Cruz Biotechnology #sc-2357, 1:5000).
• beta-blocker reverses inhibition of beta-2 adrenergic receptor resensitization by hypoxia

  Yu Sun, et al., bioRxiv - Biochemistry 2020

  Quote: ... Anti-phospho-β2AR 355/356 [40] antibody (1:500, Santa cruz) diluted in 1% goat serum was used as primary antibody ...
• Bimolecule detection for Extracellular Vesicle Screening

  Hisako Kaneda, et al., bioRxiv - Biochemistry 2020

  Quote: ... or HRP-conjugated anti-rat IgG (Santa Cruz; 1:3000-5000) were reacted at room temperature for 1 hour ...
• Bimolecule detection for Extracellular Vesicle Screening

  Hisako Kaneda, et al., bioRxiv - Biochemistry 2020

  Quote: ... HRP-conjugated anti-goat IgG (Santa Cruz, TX; 1:3000-5000), Rabbit or Mouse TrueBlot® ...
• Human Deep Cortical Neurons Promote Regeneration and Recovery After Cervical Spinal Cord Injury

  Vanessa M. Doulames, et al., bioRxiv - Neuroscience 2021

  Quote: ... NCAM (106, 1:500 dilution; Santa Cruz Biotechnology, Inc., Dallas, TX), Neurofilament-H (NFH ...
• A functional network signature in the developing cerebellum: evidence from a preclinical model of autism

  María Berenice Soria-Ortiz, et al., bioRxiv - Neuroscience 2021

  Quote: ... or rabbit anti-Actin 1:1000 (Santa Cruz, Dallas TX, USA).
• The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the lateral amygdala via cholecystokinin

  Hemin Feng, et al., bioRxiv - Neuroscience 2021

  Quote: ... sections were counter-stained with DAPI (1:10000, Santa Cruz Biotechnology) for 10 min and mounted onto slides with 70% glycerol (Santa Cruz Biotechnology ...
• Wt1 positive neurons in the hindbrain are essential for respiration

  Danny Schnerwitzki, et al., bioRxiv - Neuroscience 2019

  Quote: ... Wt1 1:100 (Santa Cruz Biotechnology, Inc., Santa Cruz, California, USA), Wt1 1:1000 (abcam ...
• Autophagy is required for midbrain dopaminergic axon development and their responsiveness to guidance cues

  M.S. Profes, A. Saghatelyan, M. Lévesque, bioRxiv - Neuroscience 2020

  Quote: ... and donkey anti-sheep HRP (1:5000; Santa Cruz, sc-2473). Membranes were covered with ECL for 1 min (Western Lightning Plus-ECL ...
• Functional diversity of PFKFB3 splice variants in glioblastomas

  Ulli Heydasch, et al., bioRxiv - Cancer Biology 2020

  Quote: ... donkey-anti-goat IgG POD (1:120000; Santa Cruz Biotechnology, Heidelberg) or goat-anti-mouse IRDye 800CW (1:15000 ...
• A genome-wide genetic screen uncovers novel determinants of human pigmentation

  Vivek K. Bajpai, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat SOX10 (1:50; 4°C overnight; Santa Cruz, sc-17342), mouse HMB45 (1:20 ...
• The beta-tubulin isotype TUBB6 controls microtubule and actin dynamics in osteoclasts

  Justine Maurin, et al., bioRxiv - Cell Biology 2021

  Quote: ... or α-tubulin (1:200, YOL3/4 Santa Cruz Biotechnologies sc53030), ARHGAP10 (1:200) ...