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4251 - 4300 of 8884 citations for 7 Chloro 3 methyl 3H 1 2 3 triazolo 4 5 d pyrimidine since 2019

• AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia

  Luting Poh, et al., bioRxiv - Neuroscience 2020

  Quote: ... and PECAM-1 (BD Pharmingen, 553370). Images were captured with an Olympus FluoView FV1000 (Olympus ...
• Design of Biologically Active Binary Protein 2D Materials

  Ariel J. Ben-Sasson, et al., bioRxiv - Synthetic Biology 2020

  Quote: ... CD31 (BD Biosciences 555444, 1:250); VE-cadherin (BD Biosciences 555661 ...
• Functional arrays of human pluripotent stem cell-derived cardiac microtissues

  Nimalan Thavandiran, et al., bioRxiv - Bioengineering 2019

  Quote: ... Collagen 1 (3.66 mg/mL) (BD), Glucose (0.3 g/mL ...
• Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

  Yujia Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... Ki67 (1:100, 550609, BD bioscience), ATP1A1 (1:200 ...
• RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

  Chao-Chieh Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... TAZ (1:1000, 560235, BD biosciences); YAP (1:1000 ...
• The H2A.J histone variant contributes to Interferon-Stimulated Gene expression in senescence by its weak interaction with H1 and the derepression of repeated DNA sequences

  Adèle Mangelinck, et al., bioRxiv - Genetics 2020

  Quote: ... anti-p16 (BD, 554079, 1:250), anti-p21 (Cell Signaling ...
• p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

  Chrysa Kapeni, et al., bioRxiv - Developmental Biology 2021

  Quote: ... CD34 (FITC RAM34, 1:200, BD), Phox2b (guinea pig ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... Fibronectin (BD Biosciences 610077, 1:1000), N-cadherin (BD Biosciences 610920 ...
• DYRK3-Controlled Phase Separation Organizes the Early Secretory Pathway

  Raffaella Gallo, Arpan Rai, Lucas Pelkmans, bioRxiv - Cell Biology 2020

  Quote: ... p230 (1:300, BD Biosciences, 611280), GCC1 (1:500 ...
• Hippocampal Egr1-dependent neuronal ensembles negatively regulate motor learning

  Veronica Brito, et al., bioRxiv - Neuroscience 2020

  Quote: ... DARPP32 (1:500, #611520, BD Transductions), NeuN (1:500 ...
• In vivo progressive degeneration of Huntington’s disease patient-derived neurons reveals human-specific pathological phenotypes

  Andrés Miguez, et al., bioRxiv - Neuroscience 2020

  Quote: ... DARPP-32 (1:1000, BD Biosciences), EM48 (1:100 ...
• DYRK3-Controlled Phase Separation Organizes the Early Secretory Pathway

  Raffaella Gallo, Arpan Rai, Lucas Pelkmans, bioRxiv - Cell Biology 2020

  Quote: ... GM130 (1:500, BD Biosciences, 610823), ERGIC53 (1:400 ...
• Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

  Tomokazu S. Sumida, et al., bioRxiv - Immunology 2020

  Quote: ... anti-PD-1 (EH12.1, BD Biosciences), anti-TIGIT (MBSA43 ...
• Age-associated B cells are critical for the control of latent gammaherpesvirus 68 infection

  Isobel C. Mouat, Iryna Shanina, Marc S. Horwitz, bioRxiv - Immunology 2021

  Quote: ... 1 μl/ml GolgiPlug (BD Biosciences), 10 ng/ml PMA (Sigma-Aldrich ...
• CENP-A overexpression drives distinct cell fates depending on p53 status

  Daniel Jeffery, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p21 1:500 (556431 BD Pharmingen), phospho-p53 (Ser15 ...
• The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation

  Xiaoling Li, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mouse α-PkaC1 (1:100, BD), mouse α-REPO (1:10 ...
• Dissecting human skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses

  Jian He, et al., bioRxiv - Developmental Biology 2020

  Quote: ... CD140a-BB515 (BD, 564594, 1:50), PDPN-APC (eBioscience ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Ki67 (BD Biosciences, 550609, 1:200), p-ERK (Cell Signaling Technology ...
• Premalignant Nf1, Trp53-null Oligodendrocyte Precursor Cells Become Stalled in a Heterogeneous State of Replication Stress Before Gliomagenesis

  Matthew D. Sutcliffe, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Fn1 (BD Biosciences #610077, 1:200), Actn1 (Cell Signaling #3134 ...
• Latent gammaherpesvirus exacerbates arthritis and requires age-associated B cells

  Isobel C. Mouat, et al., bioRxiv - Immunology 2021

  Quote: ... 1 μl/ml GolgiPlug (BD Biosciences), 10 ng/ml PMA (Sigma-Aldrich ...
• TGF-β1 drives Th9 but not Treg cells upon allergen exposure

  Stephanie Musiol, et al., bioRxiv - Immunology 2021

  Quote: ... and 1:1000 GolgiPlug (BD Bioscience). Flow cytometric analysis was performed using a BD LSRII Fortessa flow cytometer (BD Bioscience) ...
• Opposing effects of T cell receptor signal strength on CD4 T cells responding to acute versus chronic viral infection

  Marco Künzli, et al., bioRxiv - Immunology 2020

  Quote: ... PSGL-1 (BV605, 2PH1, BD, #740384), PD1 (BV785 ...
• Deciphering the role of mucosal immune responses and cervicovaginal microbiome in resistance to HIV infection in HIV-exposed seronegative (HESN) women

  Sivasankaran Munusamy Ponnan, et al., bioRxiv - Immunology 2021

  Quote: ... PD-1-PE (EH12.1-BD Bioscience), CD25-APC (M-A251-BD Bioscience ...
• Highly functional Cellular Immunity in SARS-CoV-2 Non-Seroconvertors is associated with immune protection

  Athina Kilpeläinen, et al., bioRxiv - Immunology 2021

  Quote: ... PD-1 (BV421, clone EH12.1, BD) and activation induced markers (AIM ...
• Design, immunogenicity and efficacy of a Pan-SARS-CoV-2 synthetic DNA vaccine

  Charles C. Reed, et al., bioRxiv - Immunology 2021

  Quote: ... PD-1 PE-CF594 (BD Biosciences), and ICOS BV650 (BD Biosciences ...
• TCR affinity controls the dynamics but not the functional specification of the Th1 response to mycobacteria

  Nayan D Bhattacharyya, et al., bioRxiv - Immunology 2020

  Quote: ... 1:1000 Golgi-plug (BD Biosciences) was added to the culture 5 h prior to flow cytometric analysis ...
• IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

  Joseph T. Clark, et al., bioRxiv - Immunology 2021

  Quote: ... and 1 μg/ml 2.4G2 (BD) in PBS for 1 hr at room temperature ...
• An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

  Mirja Harms, et al., bioRxiv - Immunology 2020

  Quote: ... CD3-BV650 (BD Bioscience, 1:250), CD19-BV605 (BD Bioscience ...
• An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

  Mirja Harms, et al., bioRxiv - Immunology 2020

  Quote: ... CD19-BV605 (BD Bioscience, 1:250), DAPI (BD Bioscience ...
• Deciphering the role of mucosal immune responses and cervicovaginal microbiome in resistance to HIV infection in HIV-exposed seronegative (HESN) women

  Sivasankaran Munusamy Ponnan, et al., bioRxiv - Immunology 2021

  Quote: ... CD45RO BUV395 (UCHL-1-BD Bioscience), CCR7-PEcy7 (G043H7-BD Bioscience) ...
• RTP801 REGULATES MOTOR CORTEX SYNAPTIC TRANSMISSION AND LEARNING

  L Pérez-Sisqués, et al., bioRxiv - Neuroscience 2020

  Quote: ... and TrkB (1:1000; BD Biosciences).
• Exosomal melanotransferrin as a potential biomarker for metastatic melanoma

  Anne Bonhoure, et al., bioRxiv - Cell Biology 2020

  Quote: ... Flotillin-1 (BD Biosciences, clone 18), hsc70 (Stressgen ...
• Slc26a9^P2ACre, a new CRE driver to regulate gene expression in the otic placode lineage and other FGFR2b-dependent epithelia

  Lisa D. Urness, et al., bioRxiv - Developmental Biology 2020

  Quote: ... CD44 (BD-Pharmingen 550538, 1:1000). Secondary antibodies (Alexa Fluor® 488 goat anti-rabbit IgG (Invitrogen ...
• Subepithelial Myofibroblasts Are Critical Regulators of Intestinal Epithelial Restoration

  Vanesa Fernández-Majada, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Ki67 (1:100, BD Biosciences), anti-α-SMA (1:100 ...
• Female mice exposed to low-doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

  Myriam P Hoyeck, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... mouse anti-PCNA (1:100, BD Transduction Laboratories ...
• Pharmacological Modulation of Autophagy Prevents Mutant SOD1^G93A Induced Neurotoxicity in Experimental Models of Amyotrophic Lateral Sclerosis (ALS)

  Yue Bi, et al., bioRxiv - Neuroscience 2022

  Quote: ... SQSTM1 (1:100; BD Transduction Laboratories). Then the slides were incubated with the corresponding secondary antibody for 2h.
• Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses

  Yang Li, et al., bioRxiv - Immunology 2022

  Quote: ... PD-1 (BD Biosciences, 744633, J43), Tim-3 (BioLegend ...
• p53 restoration in small cell lung cancer identifies a latent Cyclophilin-dependent necrosis mechanism

  Jonuelle Acosta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ASCL1 (1:200, BD Biosciences 556604), UCHL1 (1:200 ...
• p53 restoration in small cell lung cancer identifies a latent Cyclophilin-dependent necrosis mechanism

  Jonuelle Acosta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ASCL1 (1:1000, BD Biosciences 556604), PPIF (Cyclophilin D ...
• CRISPR-mediated correction of skeletal muscle Ca²⁺ handling in a novel DMD patient-derived pluripotent stem cell model

  Cristina Morera, et al., bioRxiv - Cell Biology 2022

  Quote: ... SSEA4 (BD Bioscience, 560796; 1:50), α-fetoprotein (R&D ...
• PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid

  Valerie Perea, et al., bioRxiv - Cell Biology 2022

  Quote: ... Tim23 (BD Transduction Labs, 1:1000), HSP60 [LK1] (Thermo Scientific ...
• Periostin⁺ stromal cells guide lymphovascular invasion by cancer cells

  Jamie L. Null, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD31 (BD Biosciences 550274, 1:50), F4/80 (BioRad MCA497 ...
• PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid

  Valerie Perea, et al., bioRxiv - Cell Biology 2022

  Quote: ... OPA1 (BD Transduction Labs, 1:2000).
• Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening

  A Hayat, et al., bioRxiv - Cancer Biology 2022

  Quote: ... EpCAM (BD BIOSCIENCES #347200, 1:40), MUC1 (BD BIOSCIENCES #743410 ...
• Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening

  A Hayat, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MUC1 (BD BIOSCIENCES #743410, 1:50), CD24 (BIOLEGEND #311135 ...
• Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling

  David M. Walter, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD45 (BD Biosciences, 553078, 1:200), and Ter-119 (BD Biosciences ...
• Cell surface receptors TREM2, CD14 and integrin α_Mβ₂ drive sinking engulfment in phosphatidylserine-mediated phagocytosis

  Daan Vorselen, et al., bioRxiv - Cell Biology 2022

  Quote: ... and pSYK (BD, pY348, 1:200) staining were performed for 1h ...
• Role of human HSPE1 for OPA1 processing independent of HSPD1

  Nelson Yeung, et al., bioRxiv - Cell Biology 2022

  Quote: ... TIM23 (1:5,000 dilution, 611223; BD), and GFP (1:5,000 dilution ...
• A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

  Patrick Essletzbichler, et al., bioRxiv - Genomics 2022

  Quote: ... eIF5A (611976, BD Biosciences, 1:20000), DHPS/DHS (ab190266 ...
• A helminth mimic of TGF-β, TGM, enhances regenerative cutaneous wound healing and modulates immune cell recruitment and activation

  Katherine E. Lothstein, et al., bioRxiv - Immunology 2022

  Quote: ... CD11c-BV421 (1:100, BD Biosciences), Ly6G-APC-Cy7 (1:60 ...