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4201 - 4250 of 8884 citations for 7 Chloro 3 methyl 3H 1 2 3 triazolo 4 5 d pyrimidine since 2019

• Interferon regulates stem cell function at all ages by orchestrating mTOR and cell cycle

  Damian Carvajal Ibañez, et al., bioRxiv - Neuroscience 2022

  Quote: ... CD45 APC-Cy7 (BD; 1:200), Prominin1-APC (eBioscience ...
• Synaptic Location Is a Determinant of the Detrimental Effects of α-Synuclein Pathology to Glutamatergic Transmission in the Basolateral Amygdala

  Liqiang Chen, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-αSyn (1:1,000, BD Biosciences Cat# 610787 ...
• An isogenic collection of pluripotent stem cell lines with elevated α-synuclein expression

  Ammar Natalwala, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-αSyn (1:1000, BD) overnight at 4°C ...
• Single-cell RNA sequencing identifies phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow

  Hongzhe Li, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1% ITS+ culture supplements (BD Biosciences) and 0.01 µg/ml TGF-ß3 (R&D Systems) ...
• Endothelial Rbpj is essential for the education of tumour-associated macrophages

  Ronja Mülfarth, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and CD45 (1:500) (BD 553076) overnight at 4°C ...
• Chemotherapy coupled to macrophage inhibition leads to enhanced T and B cell infiltration and durable triple negative breast cancer regression

  Swarnima Singh, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and Gr-1 (#559971, BD Pharmingen) and magnetically sorting using EasySep Mouse Biotin Positive Selection kit (#18559 ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Ki67 (#550609, BD Biosciences, 1:200), CD8 (4SM15 ...
• Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions

  Yingjun Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... synaptophysin (1:5000, BD Biosciences, BD611880) and PrP (1:5000 ...
• Dexamethasone Inhibits Cytokine-Induced, DUOX2-Related VEGF-A Expression and DNA damage in Human Pancreatic Cancer Cells and Growth of Pancreatic Cancer Xenografts

  Yongzhong Wu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... CD45R (BD Biosciences #553086, 1:400), CD45 (BD Biosciences #550539) ...
• Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes

  Judith Pineau, et al., bioRxiv - Cell Biology 2022

  Quote: ... DAPI (BD Bioscience, 564907, 1/1000), Saponin (Sigma ...
• Mural norrin/β-catenin signaling regulates Lama2 expression to promote neurovascular unit assembly

  Saptarshi Biswas, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rat anti-Pdgfrα (1:100; BD Biosciences ...
• Macrophage network dynamics depend on haptokinesis for optimal local surveillance

  Neil Paterson, Tim Lämmermann, bioRxiv - Immunology 2022

  Quote: ... anti-B220 (1:200 BD Horizon), anti-GFP Dylight™ 488 (1:500 ...
• High-throughput Oligopaint screen identifies druggable regulators of genome folding

  Daniel S. Park, et al., bioRxiv - Genetics 2022

  Quote: ... GSK3B (BD Biosciences 610201, 1:50). Each slide was mounted onto a coverslip and sealed with rubber cement (Elmer’s ...
• High-throughput Oligopaint screen identifies druggable regulators of genome folding

  Daniel S. Park, et al., bioRxiv - Genetics 2022

  Quote: ... GSK3B (BD Biosciences 610201, 1:1000), HDAC2 (Cell Signaling Technology 5113 ...
• E-cadherin in developing murine T cells controls spindle alignment and differentiation during β-selection

  Mirren Charnley, et al., bioRxiv - Cell Biology 2022

  Quote: ... CD25 (1:1000; BD Pharmingen, 553070), β-catenin (1:500 ...
• Separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

  Lei Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... B56 alpha (BD, 610615, 1:1000).
• Substrate trapping approach identifies TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes

  Emily Yang, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1:5000 anti-TRIM25 (BD Biosciences), 1:100 anti-RIG-I (Cell Signaling Technology ...
• A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain

  Sofia Madsen, et al., bioRxiv - Cell Biology 2022

  Quote: ... CD31 rat (1:100 BD 550274), DCX guinea pig (1:500 Merck Millipore AB253) ...
• Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis

  Tiziana Petrozziello, et al., bioRxiv - Neuroscience 2021

  Quote: ... DRP1 (1:500, BD Bioscience, CA), pDRP1-S616 (1:500 ...
• Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis

  Tiziana Petrozziello, et al., bioRxiv - Neuroscience 2021

  Quote: ... OPA1 (1:500, BD Bioscience, CA), Tomm20 (1:500 ...
• In vivo high-throughput screening of novel adeno-associated viral capsids targeting adult neural stem cells in the subventricular zone

  Sascha Dehler, et al., bioRxiv - Neuroscience 2021

  Quote: ... CD45-APC-Cy7 (BD; 1:200), GLAST (ACSA-1)-PE (Miltenyi ...
• In vivo high-throughput screening of novel adeno-associated viral capsids targeting adult neural stem cells in the subventricular zone

  Sascha Dehler, et al., bioRxiv - Neuroscience 2021

  Quote: ... CD45-APC-Cy7 (BD; 1:200), Ter119-APC-Cy7 (Biologend ...
• The KSHV ORF20 Protein Interacts With The Viral Processivity Factor ORF59 And Promote Viral Reactivation

  D. Hoffman, et al., bioRxiv - Microbiology 2020

  Quote: ... 1 μg/ml doxycycline (BD Biosciences), and 500 ng/ml ionomycin (Fisher Scientific ...
• β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

  Shikai Hu, et al., bioRxiv - Pathology 2021

  Quote: ... β- catenin (BD Biosciences, 610154, 1:500), CK-19 (DSHB ...
• DYRK3-Controlled Phase Separation Organizes the Early Secretory Pathway

  Raffaella Gallo, Arpan Rai, Lucas Pelkmans, bioRxiv - Cell Biology 2020

  Quote: ... Vti1a (1:200, BD Biosciences, 611220), TGN46 (1:600 ...
• Choroid-resident macrophages maintain local vasculature and RPE integrity and spontaneously regenerate following depletion

  Xiao Yang, et al., bioRxiv - Immunology 2019

  Quote: ... MHC-II (1:200; BD Pharmingen), or RPE65 (1:200 ...
• Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA-binding, and long term behavioral consequences

  Nathan D. Kopp, et al., bioRxiv - Genetics 2019

  Quote: ... Mouse anti-GTF2I (1:1000 BD Transduction Laboratories ...
• TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway

  Prasanna Vasudevan Iyengar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-Serine 1:1000 (612546, BD), SMURF1 1:1000 (45-K ...
• Gammaherpesvirus infection licenses age-associated B cells for pathogenicity in MS and EAE

  Isobel C. Mouat, et al., bioRxiv - Immunology 2021

  Quote: ... 1 μl/ml GolgiPlug (BD Biosciences), 10 ng/ml PMA (Sigma-Aldrich ...
• NDR1/2 kinases regulate membrane trafficking, enable efficient autophagy and prevent neurodegeneration

  Flavia Roșianu, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse GM130 (1:200, BD 610822), rabbit VPS35 (1:200 ...
• Direct specification of lymphatic endothelium from non-venous angioblasts

  Irina-Elena Lupu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... VEGFR2 (BD Pharmingen, #550549, 1:200), PECAM1 (R&D Systems ...
• Aiolos modulates the T_FH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25

  Kaitlin A. Read, et al., bioRxiv - Immunology 2022

  Quote: ... PD-1-BV421 (MIH4, BD Biosciences), CD62L-BV605 (DREG-56 ...
• Direct specification of lymphatic endothelium from non-venous angioblasts

  Irina-Elena Lupu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GM130 (BD Pharmingen, #610823, 1:100), RFP (Rockland ...
• A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer

  Zinab O. Doha, et al., bioRxiv - Cancer Biology 2022

  Quote: ... B220 (BD Bioscience #550286, 1:100); RORgt (Abcam #ab207082 ...
• Population level genetic memory of prior metabolic adaptation in E. coli

  Sophia Katz, et al., bioRxiv - Evolutionary Biology 2022

  Quote: ... 15 g L−1 agar (BD) were added to the same formulation ...
• RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

  Chao-Chieh Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... TAZ (1:100, 560235, BD biosciences); pho-histone H2AX-S139 (1:100 ...
• Antigen-driven PD-1⁺TOX⁺EOMES⁺ and PD-1⁺TOX⁺BHLHE40⁺ synovial T lymphocytes regulate chronic inflammation in situ

  Patrick Maschmeyer, et al., bioRxiv - Immunology 2019

  Quote: ... Golgi stop (1/1500; BD Biosciences) was added for the last 3 hours of stimulation ...
• NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development

  Jie Li, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-CD31 (BD, MEC13.3, 1:100), anti-PDGFR-β (R&D Systems ...
• NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development

  Jie Li, et al., bioRxiv - Developmental Biology 2019

  Quote: ... CD25-APC (BD, PC61, 1:150) or CD44-PerCP (BioLegend ...
• Macrophages Enforce the Blood Nerve Barrier

  Liza Malong, et al., bioRxiv - Neuroscience 2019

  Quote: ... CD31 (BD pharmingen 550274, 1/100), CD34 (abcam ab81289 ...
• Ureteric Bud Cells Programmed from Embryonic Stem Cells Obtain Competence for Secondary Induction in the Kidney

  Zenglai Tan, et al., bioRxiv - Developmental Biology 2019

  Quote: ... CD31 (1:100, #550274 BD Biosciences), Laminin (1:200 ...
• BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

  Drake Edwards, et al., bioRxiv - Cancer Biology 2020

  Quote: ... BrdU (1:20IF, 347580, BD Biosciences); BrdU (1:80IF ...
• Distinct cancer-associated fibroblast states drive clinical outcomes in high-grade serous ovarian cancer and are regulated by TCF21

  Ali Hussain, et al., bioRxiv - Cancer Biology 2019

  Quote: ... CD49e-PE (BD Biosciences; 1:100), EpCAM-APC (BioLegend ...
• Fine-tuned repression of Drp1 driven mitochondrial fission primes a ‘stem/progenitor-like state’ to accelerate neoplastic transformation

  B Spurlock, et al., bioRxiv - Cell Biology 2021

  Quote: ... HSP-60 (1:200; BD Bioscience); Cytokeratin 15 (western blotting ...
• FACT subunit SUPT16H associates with BRD4 and contributes to silencing of antiviral interferon signaling

  Dawei Zhou, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1 × Perm/Wash buffer (BD Biosciences) containing saponin was used for cell permeabilization ...
• The Vpu-interacting protein ATP6V0C regulates expression of tetherin and HIV-1 release

  Abdul A. Waheed, et al., bioRxiv - Microbiology 2020

  Quote: ... and anti-LAMP-1 from BD Biosciences (San Jose ...
• Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons

  ChangHui Pak, et al., bioRxiv - Neuroscience 2020

  Quote: ... MUNC18 (1:500; BD Transduction; 610336), SYT1 (1:1000 ...
• Matrix-trapped viruses can protect bacterial biofilms from invasion by colonizing cells

  Matthew C. Bond, et al., bioRxiv - Microbiology 2020

  Quote: ... Media syringes (1 mL BD plastic) were prepared by loading 1mL of 1% tryptone broth (W/V ...
• MEKK3-TGFβ crosstalk regulates inward arterial remodeling

  Hanqiang Deng, et al., bioRxiv - Pathology 2021

  Quote: ... eNOS (BD 610297; IHC 1:400), TGFβR1 (Santa Cruz sc-398 ...
• Induction Of Chronic Stress Reveals An Interplay Of Stress Granules And TDP-43 Pathological Aggregates In Human ALS Fibroblasts And iPSC-Neurons

  Antonia Ratti, et al., bioRxiv - Neuroscience 2020

  Quote: ... TIAR (1:20, BD transduction Laboratories) and TDP-43 (1:20 ...