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6001 - 6050 of 8884 citations for 7 Chloro 3 methyl 3H 1 2 3 triazolo 4 5 d pyrimidine since 2019

• A phospho-regulated signal motif determines subcellular localization of α-TAT1 for dynamic microtubule acetylation

  Abhijit Deb Roy, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-exportin-1 (mouse; BD Transduction Laboratories™; 611832). Secondary HRP antibodies were all purchased from Jackson ImmunoResearch.
• Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes

  Marco Gründl, et al., bioRxiv - Molecular Biology 2019

  Quote: ... 1:5000 and HRP Protein A (BD Biosciences, 610438) 1:5000 ...
• Mechanistic insights of radiation-induced endothelial senescence impelling glioblastoma genomic instability at relapse

  Charlotte Degorre, et al., bioRxiv - Cancer Biology 2021

  Quote: ... followed by 1/1500 mouse anti-BrdU mAb (BD) overnight to detect IdU ...
• Over-expression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification

  Masakazu Yamamoto, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and anti-CD45-bv711 (1:500; BD Biosciences, #563709). 7-AAD was also added to cell suspensions at 0.5µg/mL 10 minutes prior to identify and exclude dead/dying cells ...
• Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex

  Stephen D. Glasgow, et al., bioRxiv - Neuroscience 2020

  Quote: ... and mouse anti-DCC (1:1000; BD PharMingen, RRID:AB_395314). Blots were transferred to PBS containing horseradish peroxidase (HRP ...
• Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

  Michael Devos, et al., bioRxiv - Immunology 2020

  Quote: ... and CD44#PE (1/400; 553134) were from BD Biosciences ...
• SARS-CoV-2 induces human plasmacytoid pre-dendritic cell diversification via UNC93B and IRAK4

  Fanny Onodi, et al., bioRxiv - Immunology 2021

  Quote: ... and stained with IFNα-V450 (BD, clone 7N4-1) and TNF-α-APC (BD ...
• Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis

  Semir Beyaz, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mouse monoclonal β-catenin (1:100, BD Biosciences 610154), rabbit monoclonal OLFM4 (1:10,000 ...
• The m⁶A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

  Fugui Niu, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Strn (Striatin) (1:500, BD Biosciences 610838), rabbit anti-CART (1:2000 ...
• Immunogenicity of non-canonical HLA-I tumor ligands identified through proteogenomics

  Maria Lozano-Rabella, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and CD137-APC (BD, clone 4B4-1, 0.5:40), and in some cases mTRB-FITC (eBiosciences ...
• Mutation in the matricellular gene fibulin-4 leads to endothelial dysfunction in resistance arteries

  Michelle Lin, et al., bioRxiv - Physiology 2022

  Quote: ... primary anti-Golgi antibody (1:100, GM130, BD Biociences) at 4°C overnight ...
• Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity

  Elien Grajchen, et al., bioRxiv - Immunology 2022

  Quote: ... CD25 PE-Cy7 (clone PC61, 1:200; BD Biosciences), FOXP3 Alexa Fluor 647 (clone MF-14 ...
• Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity

  Elien Grajchen, et al., bioRxiv - Immunology 2022

  Quote: ... CD25 PE-Cy7 (clone PC61, 1:200; BD Biosciences), CD62L APC (clone MEL1 ...
• The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

  Katharina Hutter, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CD4-APC-Cy7 (BD Biosciences; 552051, 1 : 300), anti-CD8-BV421 (BioLegend ...
• Parkinson mutations in DNAJC6 cause lipid defects and neurodegeneration that are rescued by Synj1

  Julie Jacquemyn, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse α-Dynamin [1:50 (BD Biosciences, clone 41)] ...
• Adaptive immunity is required for durable responses to alectinib in murine models of EML4-ALK lung cancer

  Emily K. Kleczko, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD11c-APC/Cy7 (clone HL3; 1:100; BD Biosciences), MHCI-eF450 (clone 28-14-8 ...
• Adaptive immunity is required for durable responses to alectinib in murine models of EML4-ALK lung cancer

  Emily K. Kleczko, et al., bioRxiv - Cancer Biology 2022

  Quote: ... SigF-A647 (clone E50-2440; 1:100; BD Biosciences), CD45-AF700 (clone 30-F11 ...
• Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment

  Debolina Ganguly, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-mouse Ly-6G (1:200, BD Biosciences,551459), anti-mouse S100A9 (1:500 ...
• Caveolae couple mechanical stress to integrin recycling and activation

  Fidel-Nicolás Lolo, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-EEA-1 (BD transduction, clone 14) and mouse monoclonal anti-LBPA (Echelon Z-SLBPA) ...
• Immune-modulatory effects of low dose γ-radiation on wax moth (Galleria mellonella) larvae

  David Copplestone, et al., bioRxiv - Immunology 2022

  Quote: ... attached to a 1 ml syringe (BD Plastipak™). Treated larvae (n = 30 per condition over 3 independent experiments ...
• The Ketogenic Diet Metabolite β-Hydroxybutyrate Promotes Mitochondrial Elongation via Deacetylation and Improves Autism-like Behavior in Zebrafish

  Golam M. Uddin, et al., bioRxiv - Molecular Biology 2022

  Quote: ... DRP1 (BD Biosciences, San Jose, CA, USA; 1:1000); pDRP1S616 at (Cell Signaling ...
• The nuclear receptor NR4A1 is regulated by SUMO modification to induce autophagic cell death

  Gabriela Zárraga-Granados, et al., bioRxiv - Biochemistry 2019

  Quote: ... UBC9 (1:250, #610748 BD Biosciences, San Jose, CA); UBIQUITIN (1:1000 ...
• Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo

  Ivan-Maximiliano Kur, et al., bioRxiv - Neuroscience 2019

  Quote: ... rat anti-mouse CD31 (BD Pharmingen 557355, 1:100) and mouse Olig2 (Millipore MABN50 ...
• LSD1-mediated enhancer silencing enables endocrine cell development through attenuation of retinoic acid signalling

  Nicholas K. Vinckier, et al., bioRxiv - Developmental Biology 2019

  Quote: ... PE-conjugated anti-INS (1:50 dilution, BD Biosciences).
• Xmas ESC: A new female embryonic stem cell system that reveals the BAF complex as a key regulator of the establishment of X chromosome inactivation

  Andrew Keniry, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-mouse BV421 EpCAM (BD Biosciences, 563214; 1:100) anti-mouse ...
• Epithelial Vegfa specifies a distinct endothelial population in the mouse lung

  Lisandra Vila Ellis, et al., bioRxiv - Developmental Biology 2019

  Quote: ... BV786 rat anti-CD31 (1:250, 740870, BD Biosciences), PE/Cy7 rat anti-CD45 (1:250 ...
• JunB controls intestinal effector programs in regulatory T cells

  Joshua D. Wheaton, Maria Ciofani, bioRxiv - Immunology 2019

  Quote: ... anti-mouse IgG1 (for surface staining;A85-1; BD) and Fixable Viability Dye (Thermo-Fisher) ...
• Inhibitor of Differentiation 4 (ID4) represses myoepithelial differentiation of mammary stem cells through its interaction with HEB

  Holly Holliday, et al., bioRxiv - Developmental Biology 2020

  Quote: ... CD45-biotin (1:100, BD Biosciences, Clone 30-F11), CD31-biotin (1:40 ...
• C/EBPδ demonstrates a dichotomous role in tumor initiation and promotion of epithelial carcinoma

  Ramlogan Sowamber, et al., bioRxiv - Cancer Biology 2019

  Quote: Base agar (1% agarose Difco Agar Noble, BD biosciences) was added to 6 well plates and allowed to solidify for 5 min ...
• Vinculin anchors contractile actin to the cardiomyocyte adherens junction

  Chelsea D. Merkel, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-β-Catenin (1:250; BD Transduction Laboratories 610154), anti-Plakoglobin (1:100 ...
• Selective Liposomal Transport Through Blood Brain Barrier Disruption in Ischaemic Stroke Reveals Two Distinct Therapeutic Opportunities

  Zahraa S. Al-Ahmady, et al., bioRxiv - Neuroscience 2019

  Quote: ... Rat Anti-mouse CD31 (BD Pharmingen, 550274, 1:100), Mouse anti-mouse Cav1 (BD Biosciences ...
• Xmas ESC: A new female embryonic stem cell system that reveals the BAF complex as a key regulator of the establishment of X chromosome inactivation

  Andrew Keniry, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-mouse BV421 EpCAM (BD Biosciences, 563214; 1:100) anti-mouse ...
• pHluo_M153R-CD63, a bright, versatile live cell reporter of exosome secretion and uptake, reveals pathfinding behavior of migrating cells

  Bong Hwan Sung, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-flotillin (610820, BD Biosciences, 1:1,000 for WB), anti-GM130 (610822 ...
• pHluo_M153R-CD63, a bright, versatile live cell reporter of exosome secretion and uptake, reveals pathfinding behavior of migrating cells

  Bong Hwan Sung, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-GM130 (610822, BD Biosciences, 1:250 for WB), anti-Rab27a (69295 ...
• Wnt Regulation: Exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex

  Kristina N. Schaefer, et al., bioRxiv - Cell Biology 2019

  Quote: ... Primary antibodies used: anti-βCatenin (BD Transduction, 1:800) and anti-M2-Flag (Sigma ...
• Telophase correction refines division orientation in stratified epithelia

  Kendall J. Lough, et al., bioRxiv - Cell Biology 2019

  Quote: ... NuMA (mouse IgM, BD Transduction Labs 610562, 1:300), α-tubulin (rat ...
• Intraventricular CXCL12 is neuroprotective and increases neurogenesis in a murine model of stroke

  Laura N. Zamproni, Marimelia A. Porcionatto, bioRxiv - Neuroscience 2019

  Quote: ... and anti-CD31 (1:200, BD, Franklin Lakes, USA). After washing with PBS ...
• ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin

  Rachelle R. Olsen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Primary antibodies include: ASCL1 (556604, BD Pharmingen, 1:300), SOX9 (ab185966 ...
• Transarterial embolization modulates the immune response within target and non-target hepatocellular carcinomas

  David Tischfield, et al., bioRxiv - Immunology 2020

  Quote: ... and anti-CD45-PE-Cy5 (BD, OX1, 1:100). After surface staining ...
• Transarterial embolization modulates the immune response within target and non-target hepatocellular carcinomas

  David Tischfield, et al., bioRxiv - Immunology 2020

  Quote: ... anti-CD4-PE-Cy7 (BD, OX-35, 1:100), anti-CD8-BV510 (BD ...
• Glycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation machinery

  Vignesh Venkatakrishnan, et al., bioRxiv - Biochemistry 2020

  Quote: ... and sLex (mouse monoclonal, clone CSLEX-1, BD Biosciences). For the detection of Lewis antigens by immunoblots ...
• Polymeric Pathogen-like Particles-Based Combination Adjuvants Elicit Potent Mucosal T Cell Immunity to Influenza A Virus

  Brock Kingstad-Bakke, et al., bioRxiv - Immunology 2020

  Quote: ... and brefeldin A (1 μl/ml, GolgiPlug, BD Biosciences), with one of the following peptides ...
• IBEX: A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

  Andrea J. Radtke, et al., bioRxiv - Immunology 2020

  Quote: ... and 1% mouse or human Fc block (BD Biosciences). For conventional IF ...
• The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson’s disease

  Aurelie de Rus Jacquet, et al., bioRxiv - Neuroscience 2021

  Quote: ... and anti-CD44 (1:500, BD Biosciences, cat. # 550538) in BSA buffer (1 % BSA in PBS) ...
• Bisphosphonate drugs have actions outside the skeleton and inhibit the mevalonate pathway in alveolar macrophages

  Marcia A. Munoz, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... and streptavidin-BV421 (1:400) were purchased from BD Biosciences ...
• Time-resolved single-cell transcriptomics uncovers dynamics of cardiac neutrophil diversity in murine myocardial infarction

  Ehsan Vafadarnejad, et al., bioRxiv - Immunology 2019

  Quote: ... anti-LY6G-V450 (1:300, BD Biosciences, Clone 1A8) and Fixable Viability Staining e780 (1:1000 ...
• Arginine Methylation Regulates SARS-CoV-2 Nucleocapsid Protein Function and Viral Replication

  Ting Cai, et al., bioRxiv - Molecular Biology 2021

  Quote: ... mouse anti-SMN antibody (610646, BD Biosciences, 1:2000); rabbit anti-G3BP1 antibody (1F1 ...
• Global gene-expression analysis reveals the molecular processes underlying ClC-5 loss-of-function in novel Dent Disease 1 cellular models

  Mónica Durán, et al., bioRxiv - Pathology 2020

  Quote: ... E-Cadherin (dilution 1:1000, BD Transduction Labs, #610181), PERK (dilution 1:1000 ...
• Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

  Jeziel D. Damasceno, et al., bioRxiv - Microbiology 2019

  Quote: ... and anti-BrdU clone B44 (1: 500, BD Bioscience). Commercial secondary antibodies used here were ...
• Brain-Derived Extracellular Vesicles are Highly Enriched in the Prion Protein and Its C1 Fragment: Relevance for Cellular Uptake and Implications in Stroke

  Santra Brenna, et al., bioRxiv - Neuroscience 2019

  Quote: ... mouse antibody against GM130 (1:1000; 610822, BD Biosciences), rabbit antibody against PLP (1:1000 ...