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Citations for Tocris :
1601 - 1650 of 1725 citations for 4' Trifluoromethoxy 5 trifluoromethyl 1 1' biphenyl 3 carboxylic acid since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2021Quote: ... which is a 1:1 combination of SKSRM and neuronal maintenance medium (NMM) supplemented with 10 μM SB431542 and 1 μM dorsomorphin (both from Tocris Bioscience Inc) for 10 days for neuronal induction ...
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bioRxiv - Biophysics 2022Quote: ... or αCD45 Fab (prepared as in previous work)8 was added in a 1:10 molar ratio to the desired dye - PAJF549 (Tocris Bioscience, UK) or HM-SiR (Sarafluor-650B ...
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bioRxiv - Molecular Biology 2022Quote: ... The cell lines were maintained in mTeSR1 Plus Medium (Stemcell Technologies 100-0276 and 1 µM of Rock inhibitor (RI) (Tocris 1254). Differentiation was achieved by culturing the cells for 16 days in N2B27 media ...
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bioRxiv - Neuroscience 2022Quote: ... Non-specific binding sites were blocked by incubating the cells for 30 min in freshly-prepared blocking solution (1X TTBS, 1% bovine serum albumin (Tocris Bioscience, UK) and 0.25% Triton-X100) ...
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bioRxiv - Pathology 2023Quote: ... CoCl2 (200 μmol/L) and DPD (20 μmol/L) or the HIF-1 inhibitor chetomin (Tocris, Bristol, United Kingdom, 12 nmol/L).
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bioRxiv - Neuroscience 2021Quote: ... Amyloid plaques were stained by the β-sheet dye Methoxy-X04 (4 μg/ml in 50% ethanol, Tocris) for 30 min at RT and contrasting in 50% ethanol ...
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bioRxiv - Physiology 2023Quote: ... The dorsal muscle and skin were sutured with 4-0 sutures followed by injections of yohimbine (1.2 mg/kg, s.c.; Tocris), lactated Ringer’s solution (5 mL ...
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Pathogenic CD8 T cell responses are driven by neutrophil-mediated hypoxia in cutaneous leishmaniasisbioRxiv - Immunology 2023Quote: ... the sections were counter-stained with the nuclear probe 4’,6-diamino-2-phenylindole (DAPI, Biotechne-Tocris, UK). Slides were covered with Prolong™ Gold Antifade Mountant (Invitrogen ...
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bioRxiv - Cell Biology 2024Quote: ... Cells were washed twice with PBS and pretreated either with vehicle (media) or 100nM Ex-4 (Tocris, 1933) for 3-hours ...
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bioRxiv - Cell Biology 2020Quote: ... and diabetic NOD mice (14-26 weeks; n=3) were intra-peritoneally injected with 50mg/kg of Chloroquine diphosphate (Tocris #4109). Two hours post injection ...
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bioRxiv - Systems Biology 2020Quote: ... On Day 3 we changed the medium to RPMI + 2% B-27 (minus insulin) + 1uM Xav 939 (Tocris Bioscience, cat. 3748) and incubated the cells for 48 hours ...
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bioRxiv - Cell Biology 2020Quote: ... into fibronectin-coated wells of two 96 well plates per biological replicate to assess proliferation on day 0 (D0) and day 3 (D3) in the presence or absence of 10 μM RARβ antagonist LE135 (Tocris Bioscience) using the cell viability MTS assay ...
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bioRxiv - Physiology 2023Quote: ... PAH was induced by a single subcutaneous injection of SU5416 (SU:3-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydroindol-2-one) (Tocris, Bristol, United Kingdom) in 0.5% carboxymethyl cellulose followed by 3-weeks chronic hypoxia (9-10% O2) ...
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bioRxiv - Neuroscience 2021Quote: ... were dissolved in magnesium-free HEPES-aCSF in the presence of non-NMDA glutamate receptor blockers (CNQX, Tocris, 0190, 40 μM; Nimodipine, Tocris, 0600, 1 μM; LY-367385, Sigma, L4420, 100 μM; MPEP, Tocris, 1212, 10 μM). Type I mGluR agonist DHPG (Tocris ...
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bioRxiv - Neuroscience 2020Quote: ... slices were equilibrated for 10 minutes while being continuously superfused at room temperature with oxygenated aCSF at 1-2 ml/min containing picrotoxin (50 μM, Tocris Bioscience, MO, USA) to block GABAA receptor-mediated inhibitory responses.
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bioRxiv - Neuroscience 2022Quote: ... dissociated hiPSCs were plated at 1×104 cells/cm2 into 6-well plates in the presence of 10 µM ROCK inhibitor (Y-27632, Tocris Bioscience, Bristol, UK). Cortical and hypothalamic differentiation took place on a substrate of geltrex (1:100 ...
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bioRxiv - Neuroscience 2024Quote: ... a third group of animals were treated as those in group 2 with the addition of CB1 receptor antagonist AM251 (1 µM) (Tocris Bioscience, Bristol, UK). After 8 DIV ...
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bioRxiv - Neuroscience 2023Quote: ... The [11C]MeOTf was slowly bubbled into a reaction vial containing 0.2mg 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine precursor (Tocris, Bio-Techne Corp., Minneapolis, MN) and 0.3mL anhydrous MeCN (ThermoFisher Scientific ...
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bioRxiv - Cancer Biology 2023Quote: ... USA), nicotinamide (final concentration, 10 mmol/L) (MilliporeSigma, St. Louis, MO, USA), prostaglandin E2 (final concentration, 1 μmol/L) (Tocris Bioscience, Bristol, UK) B27 supplement (final concentration ...
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bioRxiv - Neuroscience 2023Quote: ... were dissolved in HEPES-aCSF in the presence of non-NMDA glutamate receptor blockers (CNQX, Tocris, 0190, 40 µM; Nimodipine, Tocris, 0600, 1 µM; LY-367385, Sigma, L4420, 100 µM; MPEP, Tocris, 1212, 10 µM). Type I mGluR agonist DHPG (Tocris ...
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bioRxiv - Neuroscience 2024Quote: ... hiPSCs were plated in 6-well plates in Basal Neural Maintenance media (BNMM) (Suppl. Table 1) supplemented with 10 μM SB-431542 (Tocris, Bristol, United Kingdom) and 0.5 μM LDN-193189 (Tocris ...
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bioRxiv - Animal Behavior and Cognition 2021Quote: ... ketamine hydrochloride (1.0-10.0mg/kg, t=-5 min), and nicotine (0.01-0.1mg/kg, t=-10 min) were purchased from Tocris Bioscience ...
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bioRxiv - Cell Biology 2021Quote: ... the medium was changed to differentiation medium with the addition of 5 μM of IWP2 (Tocris, 3533) for 2 days ...
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bioRxiv - Neuroscience 2022Quote: ... at the end of each experiment we applied ∼25-50µL NBQX (5 mM, Tocris, dissolved in H2O) to the surface of the cord to block recurrent excitation ...
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bioRxiv - Bioengineering 2023Quote: ... Glioblastoma medium was added to the basal side and BBB medium with 5 μM Vincristine (Tocris, 1257) added to the apical side ...
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bioRxiv - Neuroscience 2023Quote: ... behavior sessions were initiated 30 min after intraperitoneal administration of CNO (5 mg/kg, Tocris, #4936/10) or saline (200 μL) ...
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bioRxiv - Cell Biology 2024Quote: The following reagents were used at the indicated concentrations in this study: 5 µM GsMTx4 (Tocris Bioscience), 100 µM blebbistatin (Sigma ...
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bioRxiv - Cell Biology 2024Quote: ... and continuously perfused with the Ringer solution throughout the entire imaging session: Tetrodotoxin (TTX 5 µM, Tocris), D-(-)-2-Amino-5-phosphonopentanoic acid (D-APV 50 µM ...
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bioRxiv - Developmental Biology 2022Quote: ... zebrafish embryos were dechorionated with 1mg/ml pronase at 9 hpf and washed thoroughly with fresh Danieau’s buffer before being treated with 10μM (Z)-4-hydroxytamoxifen (#3412, Tocris, UK) for 2h at 28°C in the dark ...
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bioRxiv - Neuroscience 2024Quote: Recordings were performed at ∼34°C in ACSF (flow rate 2–4 ml / min) containing inhibitory receptor blockers picrotoxin (20µM; Tocris), CGP 55845 (1µM ...
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bioRxiv - Neuroscience 2021Quote: ... n=20) group were randomized to receive either saline or GLP-1R antagonist Exendin-3(9-39)amide (Ex-9) (Tocris Bioscience, UK) (85 μg/kg dissolved in saline ...
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bioRxiv - Genomics 2022Quote: ... iPS cells were grown to 80– 90% confluence and changed into CM Media supplemented with 3 μM CHIR99021 (Tocris Biosciences, Bristol, UK) for 2 days ...
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bioRxiv - Cancer Biology 2022Quote: ... Proteins were then transferred onto PVDF membranes (Cytiva, Catalog #: 10600023) using a wet transfer approach and membranes were then blocked with 3% bovine serum albumin (Tocris, Catalog #: 5217) and probed for CDC42 (Cell Signaling Technology ...
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bioRxiv - Neuroscience 2022Quote: ... food was removed for 3 hours (3 pm – 6 pm) and mice received either vehicle or CCK-8s (20 μg/kg BW; i.p.; Tocris, St. Louis, USA) injection at dark onset (6 pm ...
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bioRxiv - Neuroscience 2021Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 μM; Nimodipine, Tocris, 0600, 1 μM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
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bioRxiv - Developmental Biology 2020Quote: ... cells were treated with 1 µM SB431542 (S4317, MilliporeSigma, Burlington, MA, USA) to inhibit TGFβR1 activity or 3µM SIS3 (5291, Tocris/R&D Systems, Minneapolis, MN, USA) to inhibit SMAD3 solubilized in 50 mM DMSO ...
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bioRxiv - Cell Biology 2023Quote: ... 20 μM forskolin (solvent: DMSO, 063-02193, Fujifilm Wako Pure Chemicals, Osaka, Japan) and 1 μM LDN193189 (solvent: DMSO, 6053-10, Tocris Bioscience Bristol United Kingdom), with an induction period of 10 days.
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bioRxiv - Neuroscience 2023Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...
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bioRxiv - Neuroscience 2023Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 µM; Nimodipine, Tocris, 0600, 1 µM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
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bioRxiv - Bioengineering 2024Quote: ... FAST-STEM hiPSCs grown to 80% confluency were dissociated into single cells using TypLE for 5 minutes and seeded into the Aggrewell at a density of 1.2×105 cells per-well in 1 mL of mTesR Plus with 10 μg/mL ROCK Inhibitor Y-27632 (Tocris Bioscience, Bristol, UK; 1254) and 1% Penicillin-Streptomycin (Life Technologies ...
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bioRxiv - Bioengineering 2024Quote: ... was obtained through the administration of exponential doses with concentrations of 1 nM to 10 mM at 2 min intervals before the administration of 10 μM scopolamine (Tocris Bioscience Cat#1414/1G). After another equilibrium period ...
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bioRxiv - Neuroscience 2021Quote: ... C57bl/6j and global Gabrd-/- mice were infused with saline solution (0.9 % NaCl) or 5 μg allo (2.5 μg/μl, Tocris). For chronic unpredictable stress (CUS) ...
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bioRxiv - Molecular Biology 2020Quote: ... and 200 μL of flow buffer supplemented to a final concentration of 5 μM DFHO dye (TOCRIS Bioscience) was added prior to analysis by flow cytometry.
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bioRxiv - Genomics 2022Quote: ... and cultured for 24 hours in iPS media supplemented with 5 μM Y-27632 (Tocris Biosciences, Bristol, UK) prior to maintenance in iPS media ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... or the α7-selective nAChR antagonist methyllycaconitine citrate (MLA; 5 mg/kg in sterile saline; Tocris, Bristol, UK). These pharmacological reagents were injected s.c ...
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bioRxiv - Neuroscience 2023Quote: Gabra6-Cre::Thy1-ChR2::DREADD mice received intra-peritoneal injections of CNO (5 mg/kg; Tocris Bioscience, #4936) 60-90 min before starting eyeblink experiments.
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bioRxiv - Cancer Biology 2023Quote: ... the STING inhibitor C-176 was used at a final concentration of 5 µM (Tocris Bioscience (Bio-Techne), Bristol ...
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bioRxiv - Cell Biology 2023Quote: ... differentiation was initiated by treating the hESCs with cardiomyocyte differentiation basal medium (CDBM) with 5 mM CHIR99021 (Tocris) to activate Wnt/β-catenin signaling and form the mesendoderm layer ...
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bioRxiv - Cell Biology 2024Quote: To induce DNA damage cells were treated with 5 µM or 25 µM of cisplatin (CSP; Tocris #2251) and 13 µM of bleomycin (BLE ...
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bioRxiv - Physiology 2024Quote: ... the medium was replaced by RPMI1640 medium supplemented with B27 minus insulin and 5 μM IWP2 (Tocris Biosciences). On day 5 ...