Labshake search
Citations for Tocris :
1551 - 1600 of 1725 citations for 4' Trifluoromethoxy 5 trifluoromethyl 1 1' biphenyl 3 carboxylic acid since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2024Quote: ... coated 6-well plates with 1-1.5 million cells per well in E8 with 10 μM ROCK inhibitor Y-27632 (Tocris 1254). At day 1 of differentiation medium was exchanged to induction medium (IM ...
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bioRxiv - Neuroscience 2020Quote: ... the GABAA channel blocker Picrotoxin (50 µM) or the GABAB antagonist CGP-54626 (3 µM) (Tocris Bioscience, Minneapolis, MN) was bath applied 80 min prior to HFS ...
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bioRxiv - Developmental Biology 2020Quote: ... day 3 NMP-like cell cultures were treated with Accutase and replated at a density of 63,000 cells//cm2 in N2B27 supplemented with CHIR99021 (3 µM, Tocris), FGF2 (100 ng/ml ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... N,N’-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride (IT1t) was purchased from Tocris (United Kingdom). Bovine serum albumin ...
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bioRxiv - Cell Biology 2024Quote: ... Cultures were passaged every 6 days and kept in a cycle of 3 days in 5μM ROCK inhibitor (Y-27632 dihydrochloride; Tocris), 3 days in the absence of rock inhibitor ...
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bioRxiv - Neuroscience 2023Quote: Pharmacological inhibition of AQP4 was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience, UK). Unless otherwise stated ...
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Sexual dimorphism of insular cortex function in persistent alcohol drinking despite aversion in micebioRxiv - Neuroscience 2023Quote: ... The causal role of aIC or pIC glutamatergic neurons on drinking was tested after injection of CNO (i.p. 3 mg/kg in NaCl, Tocris) or vehicle 30 minutes before the last session of binge (day 18) ...
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bioRxiv - Immunology 2024Quote: ... we administered 3 doses (100 uL) of either vehicle control or 50 ug of the CCR3 antagonist (SB328437, Tocris) via intraperitoneal injection before TAC and during the first week of recovery ...
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bioRxiv - Neuroscience 2020Quote: ... the N3 media was further supplemented with two factors: SB-431542 (5 µM, Tocris, 1614) and LDN-193189 (100 nM ...
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bioRxiv - Immunology 2022Quote: ... or an inhibitor of CD73 inhibitor (adenosine 5’-(α, β-methylene) diphosphate (AMP-CP; Tocris) (0.5 mg/mouse ...
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bioRxiv - Neuroscience 2021Quote: ... glutamate and GABA receptor blockers (10 μM NBQX, Tocris, UK, 1044; 5 μM CPP, Tocris, 0247 ...
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bioRxiv - Cell Biology 2021Quote: ... SB431542 (#1614) and guanosine 5′-[β,γ-imido]triphosphate (GMPPNP, #G0635) were purchased from Tocris and Sigma-Aldrich ...
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bioRxiv - Neuroscience 2022Quote: ... for 5 min at 37°C and replating in 10μM ROCK inhibitor Y-27632 (Tocris) for 24h.
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bioRxiv - Neuroscience 2021Quote: ... Cdk-5 inhibitor (Roscovitine, 10 µM) and GSK-3β inhibitor CHIR 98014 (10 µM, Tocris) were added 30 min prior to IL-13 treatment ...
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bioRxiv - Neuroscience 2022Quote: ... 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate (ARL 67156; Tocris, 1283) was perfused through the probe at concentrations of 1 mM ...
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bioRxiv - Neuroscience 2022Quote: ... The two agents used were a mixture of AMPA (5 mM) (Cat no. 0254, Tocris) and NMDA (10 mM ...
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bioRxiv - Neuroscience 2023Quote: ... we applied for 5 minutes the specific sodium channel blocker tetrodotoxin (TTX, 500 nM, Tocris) in combination with potassium channel blocker 4-aminopyridine (4-AP ...
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bioRxiv - Bioengineering 2023Quote: ... or pharmacological inhibitors of focal adhesion kinase (FAK) (FAK inhibitor 14, 5 µM, Tocris, UK), Rho-associated protein kinase (ROCK ...
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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesisbioRxiv - Cell Biology 2023Quote: ... the medium was replaced with differentiation medium containing 5 μM IWP-2 (TOCRIS, Cat.# 3533), a Wnt inhibitor ...
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bioRxiv - Cell Biology 2024Quote: ... then blocked in Tween 0.1% Tris-buffered saline containing 5% bovine serum albumin (Tocris 5217) for at least 1h at room temperature and subsequently incubated overnight at 4°C with primary antibodies ...
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bioRxiv - Neuroscience 2021Quote: ... SR95531 (gabazine) and 4-methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate) were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Animal Behavior and Cognition 2022Quote: ... Either α-cyano-4-hydroxycinnamate (CHC, daily i.p. injection of 15 mg/kg, Tocris Bioscience, Bristol, UK) plus metformin (Met ...
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bioRxiv - Physiology 2023Quote: ... Reagents added to cell culture media are as follows: 250 μM 4-octyl itaconate (Tocris Bioscience, 6662), 4μM Etomoxir (Sigma ...
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bioRxiv - Neuroscience 2021Quote: ... To interfere with group I metabotropic glutamate receptor (mGluR) signaling we used bath application of either the mGlu1 receptor antagonist YM298198 (1 μM, Tocris, Germany) or the mGluR5 receptor antagonist MPEP (10 μM ...
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bioRxiv - Neuroscience 2020Quote: ... in either plain Tyrode (stimulated condition) or Ca2+-free Tyrode containing 1mM EGTA and 1 μM TTX (#1069; Tocris Bioscience, Germany) (unstimulated condition) ...
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bioRxiv - Neuroscience 2020Quote: ... To assess the monosynaptic nature of BLA-EPSCs recordings were obtained in the presence of (in μM): 1 TTX (Tocris Bioscience), 100 4-aminopyridine (4-AP ...
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bioRxiv - Genetics 2022Quote: ... cells were seeded in a 96-well plate on a feeder layer at a low density (~ 1 cell per well) in XEN media supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris #1254) until clones appeared (approximately 5 days) ...
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bioRxiv - Neuroscience 2023Quote: ... Miniature excitatory postsynaptic currents (mEPSCs) and miniature inhibitory postsynaptic currents (mIPSCs) were recorded in the presence of 1 μM Tetrodotoxin (Tocris, 1069) at a holding voltage of -60 mV and +10mV ...
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bioRxiv - Cell Biology 2024Quote: ... + 10 μM Tranylcypromine (2-PCPA) HCl (DMSO; Selleckchem S4246) + 20 μM Forskolin (DMSO; Selleckchem S2449) + 1 μM Ch 55 (DMSO; Tocris 2020) + 5 μM EPZ004777 (DMSO ...
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bioRxiv - Neuroscience 2024Quote: ... To enhance their neuronal fate NSC medium was enriched by 1 µM dorsomorphin (Stemgent, USA) and 10 µM SB-431542 (Tocris, UK). The selected neurorosettes were allowed to form neurospheres in T25 flasks ...
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bioRxiv - Cell Biology 2024Quote: THP-1 cells were differentiated in complete media with phorbol 12-myristate-13-acetate (PMA; 100 nM) (cat no. 1201/1; Tocris, UK) for 72 hr ...
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bioRxiv - Neuroscience 2023Quote: ... maneuvered adjacent to the capillary under study and pressurized injections (200–300 ms, 7 ± 1 PSI) of 100 nM T-peptide (Tocris, USA) with tetramethylrhodamine isothiocyanate (TRITC ...
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bioRxiv - Neuroscience 2023Quote: ... Mossy fiber purity of signals was verified at the end of each recording with the application of 1 µM DCG-IV (#0975, Tocris Bioscience). All recordings with a suppression of at least 75% of the signal were used for analysis.
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bioRxiv - Genetics 2023Quote: ... and 10 µg of the Lenti guide puro/blast-gRNA plasmid using 1 mg/ml of PEI transfection reagent (Tocris, 7854). Incubation with the transfection mix was done for 5 hours at 37 °C ...
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bioRxiv - Cell Biology 2023Quote: ... Cells which efficiently depleted WAPL were identified using confocal microscopy and Western blotting after treatment of the cells with 1 µM dTAG-7 (Tocris, 6912) for 3 h ...
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bioRxiv - Cancer Biology 2023Quote: Cells grown in normal culture media supplemented with 10 ng/ml doxycycline for 48 hours to induce shRNA or treated with 1 μM TCE5003 (Tocris, 5099) for 22 hours ...
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bioRxiv - Neuroscience 2023Quote: ... To obtain an alternative blockade of N-type VGCCs we used N-[[4-(1,1-Dimethylethyl)phenyl]methyl-N-methyl-L-leucyl-N-(1,1-dimethylethyl)-O-phenylmethyl)-L-tyrosinamide (pd173212, purchased from TOCRIS, Bristol, UK) that was used at the final concentration of 5 µM ...
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bioRxiv - Physiology 2023Quote: ... the cell medium was replaced with the experimental medium (2 ml/well) consisting of DMEM containing 1 nM of 1,25-dihydroxyvitamin D3 (Tocris; Cat. #2551), as described previously58 ...
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bioRxiv - Biophysics 2024Quote: ... in the presence of 1 mM ligands (glutamate and glycine) and in the presence or absence of 30 μM GNE-9278 (Tocris Bioscience).
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bioRxiv - Neuroscience 2024Quote: ... animals were intraperitoneally (i.p.) injected with saline (Vehicle, 0.9 % NaCl) or Clonazepine N-Oxide (1 mg/kg) (CNO, Tocris Bioscience Cat# 6329). After i.p ...
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bioRxiv - Neuroscience 2021Quote: ... Hox propagation was initiated by activation of Wnt signaling using NMP media comprised of E6 medium supplemented with 200 ng/mL FGF8b and 3 μM CHIR99021 (Tocris). This constitutes the “Hox timepoint” of 0hrs ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... 0.3 or 1 mg/kg of the mGlu2/3 receptor agonist LY379268 (Cat No.: 2453, Batch No.: 9B/232416, CAS No.: 191471-52-0, Tocris Bioscience ...
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bioRxiv - Bioengineering 2023Quote: ... The media were changed at day 3 to remove the ROCK inhibitor and to add 10 µM DAPT (Tocris Bioscience), which remained until day 7 ...
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bioRxiv - Cell Biology 2023Quote: iPSCs were first differentiated into iAT2s and passaged as above in 3D cultures in iAT2 medium (CK+DCI) supplemented for the first 3 days after passaging with 10 uM Y-27632 (Tocris). To generate iAT1s ...
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bioRxiv - Neuroscience 2023Quote: ... Extracellular action potentials were recorded in 3 independent cultures for either genotype in the presence of 50nM nifedipine (Tocris Bioscience) or vehicle using the MaestroPro (Axion Biosystems ...
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bioRxiv - Developmental Biology 2024Quote: Incretin mimetic drug treatments were performed by supplementing unmodified Arc-3 medium with Metformin hydrochloride at 10 µM (Tocris, 2864), Exendin-4 at 10 nM (Tocris ...
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bioRxiv - Neuroscience 2023Quote: ... 5-HT1A-R agonist 8-OH-DPAT or antagonist NAN-190 (NAN) were from Tocris (UK). Competition was performed at concentration between 10−11 to 10−5 M ...
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bioRxiv - Neuroscience 2023Quote: ... The following peptides were delivered in 5 µL of sterile saline: GRP (295 ng, Tocris 1789), Substance P (400 ng ...
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Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutationbioRxiv - Pathology 2023Quote: ... cells were treated with RPMI enriched with insulin-free B27 and 5 µM IWP2 (Tocris Bioscience) for 48 hours and then the medium was replaced with RPMI enriched with insulin-free B27 ...
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bioRxiv - Neuroscience 2024Quote: ... All experiments were performed in the presence of SR95531 (5 mM, Tocris Bio-Techne, Minneapolis, MN) and CGP55845 (2.5 mM Tocris ...